The network for 'reproduction' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms


The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms.

NameDescriptionProbabilityFunc Analog Organism
Hcrtr1hypocretin (orexin) receptor 10.540
Pfn1profilin 10.514
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.440
Ptprhprotein tyrosine phosphatase, receptor type, H0.386
Neflneurofilament, light polypeptide0.380
Cd44Cd44 molecule0.346
Olr1493olfactory receptor gene Olr14930.331
Nedd4neural precursor cell expressed, developmentally down-regulated 40.323
Gipgastric inhibitory polypeptide0.305
Mapk3mitogen activated protein kinase 30.293
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.292
Slco2a1solute carrier organic anion transporter family, member 2a10.286
Ywhaqtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.281
Serpine1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.280
Fgf2fibroblast growth factor 20.280
Ptafrplatelet-activating factor receptor0.273
Trhr2thyrotropin releasing hormone receptor 20.262
Gad2glutamate decarboxylase 20.261
Hspd1heat shock protein 1 (chaperonin)0.260
Ugt2b7UDP glucuronosyltransferase 2 family, polypeptide B70.260
Sstr1somatostatin receptor 10.260
Scnn1gsodium channel, nonvoltage-gated 1, gamma0.260
Ptgs2prostaglandin-endoperoxide synthase 20.259
Tpm4tropomyosin 40.258
Pipprolactin induced protein0.257
Fth1ferritin, heavy polypeptide 10.255
Makmale germ cell-associated kinase0.255
Cgaglycoprotein hormones, alpha polypeptide0.250
Tpm3tropomyosin 3, gamma0.248
Ednrbendothelin receptor type B0.245
Fgfr2fibroblast growth factor receptor 20.242
Aqp9aquaporin 90.238
Pde1cphosphodiesterase 1C0.237
Leprleptin receptor0.236
Apba1amyloid beta (A4) precursor protein-binding, family A, member 10.231
Fat2FAT tumor suppressor homolog 2 (Drosophila)0.230
Trhrthyrotropin releasing hormone receptor0.229
Lalbalactalbumin, alpha0.226
Scn4asodium channel, voltage-gated, type IV, alpha subunit0.224
Myh9myosin, heavy chain 9, non-muscle0.223
CnbpCCHC-type zinc finger, nucleic acid binding protein0.223
Bbxbobby sox homolog (Drosophila)0.222
Snap25synaptosomal-associated protein 250.220
Acvr1cactivin A receptor, type IC0.220
Atp12aATPase, H+/K+ transporting, nongastric, alpha polypeptide0.220
Pthparathyroid hormone0.219
Tas2r118taste receptor, type 2, member 1180.216
Prl8a7prolactin family 8, subfamily a, member 70.212
Cand1cullin-associated and neddylation-dissociated 10.211
Flt1FMS-related tyrosine kinase 10.210
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.210
Anxa2annexin A20.208
Syt4synaptotagmin IV0.206
Caprin1cell cycle associated protein 10.203
Homer3homer homolog 3 (Drosophila)0.201
Grin3aglutamate receptor, ionotropic, N-methyl-D-aspartate 3A0.199
Olr857olfactory receptor 8570.198
Nfibnuclear factor I/B0.197
Cxcl2chemokine (C-X-C motif) ligand 20.196
Nfianuclear factor I/A0.195
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.195
Arf1ADP-ribosylation factor 10.194
Cct3chaperonin containing Tcp1, subunit 3 (gamma)0.189
Snap91synaptosomal-associated protein 910.188
Lhbluteinizing hormone beta0.185
Rap1bRAP1B, member of RAS oncogene family0.185
Thoc2THO complex 20.184
Chrna2cholinergic receptor, nicotinic, alpha 2 (neuronal)0.183
Cacnb4calcium channel, voltage-dependent, beta 4 subunit0.183
Capza3capping protein (actin filament) muscle Z-line, alpha 30.182
Kcnh1potassium voltage-gated channel, subfamily H (eag-related), member 10.182
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.181
Cltcclathrin, heavy chain (Hc)0.180
Il8rbinterleukin 8 receptor, beta0.180
Adarb2adenosine deaminase, RNA-specific, B20.180
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.178
Pebp1phosphatidylethanolamine binding protein 10.177
Tacr1tachykinin receptor 10.175
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.175
Aqp2aquaporin 2 (collecting duct)0.174
Bmpr1abone morphogenetic protein receptor, type IA0.173
Ptgfrprostaglandin F receptor0.172
Actr3ARP3 actin-related protein 3 homolog (yeast)0.171
Nr4a1nuclear receptor subfamily 4, group A, member 10.171
Testintestin gene0.171
Ifitm3interferon induced transmembrane protein 30.171
Avpr2arginine vasopressin receptor 20.170
Eef2eukaryotic translation elongation factor 20.169
Odf1outer dense fiber of sperm tails 10.169
Jak2Janus kinase 20.168
Prlhrprolactin releasing hormone receptor0.168
Kalrnkalirin, RhoGEF kinase0.168
Cryba1crystallin, beta A10.168
Nab1Ngfi-A binding protein 10.166
Gjb3gap junction protein, beta 30.165
Egr1early growth response 10.165
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
piwil1piwi-like 1 (Drosophila)0.913
rpl19ribosomal protein L190.843
bmp2bbone morphogenetic protein 2b0.785
cyp11a1cytochrome P450, subfamily XIA, polypeptide 10.778
neo1neogenin 10.770
pkd2polycystic kidney disease 20.769
tcp1t-complex polypeptide 10.744
metmet proto-oncogene (hepatocyte growth factor receptor)0.737
nop58NOP58 ribonucleoprotein homolog (yeast)0.732
gro1groucho 10.729
nanos3nanos homolog 30.714
tp53tumor protein p530.709
rps3aribosomal protein S3A0.707
slc12a2solute carrier family 12 (potassium/chloride transporters), member 20.666
notch3notch homolog 30.642
notch1anotch homolog 1a0.635
cct7chaperonin containing TCP1, subunit 7 (eta)0.612
tfap2atranscription factor AP-2 alpha0.586
rps15aribosomal protein S15a0.577
mibmind bomb0.567
cct5chaperonin containing TCP1, subunit 5 (epsilon)0.556
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.543
snrpcsmall nuclear ribonucleoprotein polypeptide C0.538
psmb3proteasome (prosome, macropain) subunit, beta type, 30.530
top2atopoisomerase (DNA) II alpha0.503
hspa5heat shock protein 50.480
fgfr1afibroblast growth factor receptor 1a0.479
rps18ribosomal protein S180.478
atp6v0caATPase, H+ transporting, lysosomal, V0 subunit c, a0.472
rpl7ribosomal protein L70.459
pabpc1apoly A binding protein, cytoplasmic 1 a0.456
atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.451
gpr126G protein-coupled receptor 1260.451
plcg1phospholipase C, gamma 10.431
rps8aribosomal protein S8a0.430
sema3aasemaphorin 3aa0.427
psmb4proteasome (prosome, macropain) subunit, beta type, 40.423
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.422
bmp4bone morphogenetic protein 40.419
bmp2abone morphogenetic protein 2a0.416
alcambactivated leukocyte cell adhesion molecule b0.392
gli1GLI-Kruppel family member 10.392
rpl28ribosomal protein L280.379
lhx1aLIM homeobox 1a0.368
gdf6agrowth differentiation factor 6a0.365
ruvbl2RuvB-like 2 (E. coli)0.363
hsp90a.1heat shock protein 90-alpha 10.360
pax2apaired box gene 2a0.355
rpl35ribosomal protein L350.355
rpsaribosomal protein SA0.355
wnt11rwingless-type MMTV integration site family, member 11, related0.354
smosmoothened homolog (Drosophila)0.352
atp1a1a.4ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide0.352
dlatdihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)0.349
rps11ribosomal protein S110.347
rpl12ribosomal protein L120.347
eif3deukaryotic translation initiation factor 3, subunit D0.346
rpl36aribosomal protein L36A0.339
rps29ribosomal protein S290.339
crabp2acellular retinoic acid binding protein 2, a0.334
egr1early growth response 10.319
pbx4pre-B-cell leukemia transcription factor 40.314
rps7ribosomal protein S70.309
tpbgltrophoblast glycoprotein-like0.309
mef2camyocyte enhancer factor 2ca0.307
ilkintegrin linked kinase0.307
eif3geukaryotic translation initiation factor 3, subunit G0.305
zmat2zinc finger, matrin type 20.304
six4bsine oculis homeobox homolog 4b0.298
per3period homolog 3 (Drosophila)0.290
mef2dmyocyte enhancer factor 2d0.284
rpl7l1ribosomal protein L7-like 10.282
pou5f1POU domain, class 5, transcription factor 10.282
got2bglutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate aminotransferase 2)0.274
sf3b14splicing factor 3B0.274
ptpn11aprotein tyrosine phosphatase, non-receptor type 11, a0.273
rpl6ribosomal protein L60.269
aurkbaurora kinase B0.266
eif3ceukaryotic translation initiation factor 3, subunit C0.252
khdrbs1bKH domain containing, RNA binding, signal transduction associated 1b0.251
ptgs2aprostaglandin-endoperoxide synthase 2a0.250
hhiphedgehog interacting protein0.237
gata3GATA-binding protein 30.237
rpl21ribosomal protein L210.235
mef2amyocyte enhancer factor 2a0.234
fanclFanconi anemia, complementation group L0.231
psmc6proteasome (prosome, macropain) 26S subunit, ATPase, 60.228
mllmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.227
rbb4retinoblastoma binding protein 40.226
pax7apaired box gene 7a0.225
slc6a6solute carrier family 6 (neurotransmitter transporter, taurine), member 60.225
rps12ribosomal protein S120.224
ptch2patched 20.223
snai1bsnail homolog 1b (Drosophila)0.221
ppm1gprotein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform0.219
myhz2myosin, heavy polypeptide 2, fast muscle specific0.218
cct6achaperonin containing TCP1, subunit 6A (zeta 1)0.217
hn1lhematological and neurological expressed 1-like0.214
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.981
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.929
RB1retinoblastoma 10.778
QKIquaking homolog, KH domain RNA binding (mouse)0.765
CDK2cyclin-dependent kinase 20.750
HNRNPKheterogeneous nuclear ribonucleoprotein K0.739
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.695
CSNK2Bcasein kinase 2, beta polypeptide0.689
PSMD1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.688
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.584
CCT2chaperonin containing TCP1, subunit 2 (beta)0.579
CDC5LCDC5 cell division cycle 5-like (S. pombe)0.579
DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked0.565
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.527
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.511
SP1Sp1 transcription factor0.492
TP53tumor protein p530.473
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.459
BRCA1breast cancer 1, early onset0.405
HSPA9heat shock 70kDa protein 9 (mortalin)0.394
EP300E1A binding protein p3000.389
CAND1cullin-associated and neddylation-dissociated 10.377
ATXN1ataxin 10.369
MAPK14mitogen-activated protein kinase 140.368
CCT3chaperonin containing TCP1, subunit 3 (gamma)0.357
RNPS1RNA binding protein S1, serine-rich domain0.353
NPM1nucleophosmin (nucleolar phosphoprotein B23, numatrin)0.352
HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 10.336
HNRNPUheterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)0.332
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.319
CSNK2A1casein kinase 2, alpha 1 polypeptide0.318
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.312
AKT1v-akt murine thymoma viral oncogene homolog 10.306
PSMA4proteasome (prosome, macropain) subunit, alpha type, 40.300
CREBBPCREB binding protein0.299
COPS5COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)0.296
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.293
SRSF2serine/arginine-rich splicing factor 20.292
SNW1SNW domain containing 10.292
PSMA7proteasome (prosome, macropain) subunit, alpha type, 70.279
TARDBPTAR DNA binding protein0.272
JUNjun proto-oncogene0.258
ATF2activating transcription factor 20.254
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.250
PRPF4PRP4 pre-mRNA processing factor 4 homolog (yeast)0.245
TCP1t-complex 10.243
ILF3interleukin enhancer binding factor 3, 90kDa0.240
ESR1estrogen receptor 10.239
EIF3Aeukaryotic translation initiation factor 3, subunit A0.235
MSH2mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)0.235
KPNA2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)0.232
CCT7chaperonin containing TCP1, subunit 7 (eta)0.230
PSMB3proteasome (prosome, macropain) subunit, beta type, 30.225
EBNA1BP2EBNA1 binding protein 20.213
NCOA3nuclear receptor coactivator 30.212
RUVBL2RuvB-like 2 (E. coli)0.209
SNRPA1small nuclear ribonucleoprotein polypeptide A'0.208
RBFOX2RNA binding protein, fox-1 homolog (C. elegans) 20.206
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.201
EIF2S1eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa0.198
RFC4replication factor C (activator 1) 4, 37kDa0.198
AHSA1AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)0.196
PPP2R1Aprotein phosphatase 2, regulatory subunit A, alpha0.196
RAD21RAD21 homolog (S. pombe)0.193
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.193
FOSFBJ murine osteosarcoma viral oncogene homolog0.193
CUL1cullin 10.192
MCM7minichromosome maintenance complex component 70.189
EIF3Beukaryotic translation initiation factor 3, subunit B0.183
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.182
PSMD13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.181
EGFRepidermal growth factor receptor0.180
CCNB1cyclin B10.178
UCHL5ubiquitin carboxyl-terminal hydrolase L50.177
U2AF1U2 small nuclear RNA auxiliary factor 10.177
TRA2Btransformer 2 beta homolog (Drosophila)0.175
RANRAN, member RAS oncogene family0.174
CBX5chromobox homolog 50.169
PSMB5proteasome (prosome, macropain) subunit, beta type, 50.168
SRPK2SRSF protein kinase 20.157
UBCubiquitin C0.153
EIF4A1eukaryotic translation initiation factor 4A10.152
SRPK1SRSF protein kinase 10.152
CCNA2cyclin A20.152
XIAPX-linked inhibitor of apoptosis0.151
KARSlysyl-tRNA synthetase0.151
CHEK1CHK1 checkpoint homolog (S. pombe)0.150
MATR3matrin 30.149
PRPF19PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)0.148
SF3B1splicing factor 3b, subunit 1, 155kDa0.147
EIF4A3eukaryotic translation initiation factor 4A30.147
MCM4minichromosome maintenance complex component 40.145
CCT6Achaperonin containing TCP1, subunit 6A (zeta 1)0.142
RPL21ribosomal protein L210.142
MCM3minichromosome maintenance complex component 30.140
SFPQsplicing factor proline/glutamine-rich0.139
CCT4chaperonin containing TCP1, subunit 4 (delta)0.139
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.138
MAGOHmago-nashi homolog, proliferation-associated (Drosophila)0.137
NME1non-metastatic cells 1, protein (NM23A) expressed in0.136
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism