The network for 'folic acid containing compound metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

folic acid containing compound metabolic process

The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units.

NameDescriptionProbabilityFunc Analog Organism
Rnaseh2bribonuclease H2, subunit B0.346
Ahcyadenosylhomocysteinase0.297
Pcdhga11protocadherin gamma subfamily A, 110.102
Kmokynurenine 3-monooxygenase (kynurenine 3-hydroxylase)0.095
Hfehemochromatosis0.092
Bmp7bone morphogenetic protein 70.092
Casp6caspase 60.092
Parp1poly (ADP-ribose) polymerase 10.091
Shmt2serine hydroxymethyltransferase 2 (mitochondrial)0.088
Nde1nudE nuclear distribution gene E homolog 1 (A. nidulans)0.083
Pctpphosphatidylcholine transfer protein0.080
Slc25a13solute carrier family 25, member 13 (citrin)0.076
Unguracil-DNA glycosylase0.075
Wdr77WD repeat domain 770.059
Polr1bpolymerase (RNA) I polypeptide B0.056
Sf3b3splicing factor 3b, subunit 30.053
Msh2mutS homolog 2 (E. coli)0.052
Olr1701olfactory receptor 17010.051
Hn1lhematological and neurological expressed 1-like0.051
Mlh1mutL homolog 1 (E. coli)0.049
Hnf1aHNF1 homeobox A0.045
Casp7caspase 70.045
Srprsignal recognition particle receptor ('docking protein')0.044
Aldh18a1aldehyde dehydrogenase 18 family, member A10.040
Gspt1G1 to S phase transition 10.040
Nolc1nucleolar and coiled-body phosphoprotein 10.038
Acsm3acyl-CoA synthetase medium-chain family member 30.037
Procprotein C0.035
Cyp2c23cytochrome P450, family 2, subfamily c, polypeptide 230.033
Tymsthymidylate synthetase0.032
Rad51cRad51 homolog c (S. cerevisiae)0.031
Sardhsarcosine dehydrogenase0.031
Creb1cAMP responsive element binding protein 10.030
LOC259245alpha-2u globulin PGCL50.029
Dhfrdihydrofolate reductase0.028
Rbp2retinol binding protein 2, cellular0.028
Rpa2replication protein A20.028
Cyp1a1cytochrome P450, family 1, subfamily a, polypeptide 10.028
FasFas (TNF receptor superfamily, member 6)0.028
Prim2primase, DNA, polypeptide 20.028
Afpalpha-fetoprotein0.028
Clptm1lCLPTM1-like0.027
Agpsalkylglycerone phosphate synthase0.026
Dio1deiodinase, iodothyronine, type I0.025
Hspb2heat shock protein beta 20.025
Brca1breast cancer 10.025
Pck1phosphoenolpyruvate carboxykinase 1 (soluble)0.023
Cyp2d2cytochrome P450, family 2, subfamily d, polypeptide 20.023
Rassf9Ras association (RalGDS/AF-6) domain family (N-terminal) member 90.022
Ces1ccarboxylesterase 1C0.022
Shmt1serine hydroxymethyltransferase 1 (soluble)0.022
Slc17a1solute carrier family 17 (sodium phosphate), member 10.021
Pola1polymerase (DNA directed), alpha 10.021
Ccne1cyclin E10.021
Rgnregucalcin (senescence marker protein-30)0.021
Akr1c14aldo-keto reductase family 1, member C140.020
Mthfd1methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase0.020
Timelesstimeless homolog (Drosophila)0.020
Chek1CHK1 checkpoint homolog (S. pombe)0.020
RGD1305274similar to RIKEN cDNA 2010305A190.020
Foxm1forkhead box M10.019
Srmspermidine synthase0.019
Sec61a1Sec61 alpha 1 subunit (S. cerevisiae)0.019
Gulogulonolactone (L-) oxidase0.019
Mipepmitochondrial intermediate peptidase0.018
Tmem185btransmembrane protein 185B0.018
F10coagulation factor X0.017
Soat1sterol O-acyltransferase 10.017
Psmc3ipPSMC3 interacting protein0.017
Abcb11ATP-binding cassette, subfamily B (MDR/TAP), member 110.017
Mgst2microsomal glutathione S-transferase 20.016
Acvr1bactivin A receptor, type IB0.016
Tk1thymidine kinase 1, soluble0.016
Aldh6a1aldehyde dehydrogenase 6 family, member A10.016
Enpp3ectonucleotide pyrophosphatase/phosphodiesterase 30.015
Fabp1fatty acid binding protein 1, liver0.015
Slc30a7solute carrier family 30 (zinc transporter), member 70.015
Emdemerin0.015
Ppp1r3bprotein phosphatase 1, regulatory (inhibitor) subunit 3B0.015
Mybbp1aMYB binding protein (P160) 1a0.015
Slco2a1solute carrier organic anion transporter family, member 2a10.014
Polr3bpolymerase (RNA) III (DNA directed) polypeptide B0.014
Aqp9aquaporin 90.014
Anp32bacidic (leucine-rich) nuclear phosphoprotein 32 family, member B0.014
Gcgroup specific component0.014
Ddx54DEAD (Asp-Glu-Ala-Asp) box polypeptide 540.014
Dph1DPH1 homolog (S. cerevisiae)0.014
Cenpicentromere protein I0.014
Tmpothymopoietin0.014
Gcs1glucosidase 10.014
Fert2fer (fms/fps related) protein kinase, testis specific 20.013
Aldh4a1aldehyde dehydrogenase 4 family, member A10.013
Atxn3ataxin 30.013
Pold3polymerase (DNA-directed), delta 3, accessory subunit0.013
Gcgrglucagon receptor0.013
Fdxrferredoxin reductase0.013
Agxt2alanine-glyoxylate aminotransferase 20.013
Irf2interferon regulatory factor 20.013
Slc19a1solute carrier family 19 (folate transporter), member 10.012
Rcc2regulator of chromosome condensation 20.012
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
pycardPYD and CARD domain containing0.016
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
YARStyrosyl-tRNA synthetase0.073
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Asnsasparagine synthetase0.782
Slc11a2solute carrier family 11 (proton-coupled divalent metal ion transporters), member 20.694
Psat1phosphoserine aminotransferase 10.450
Hpd4-hydroxyphenylpyruvic acid dioxygenase0.298
Aldh18a1aldehyde dehydrogenase 18 family, member A10.296
Slc7a5solute carrier family 7 (cationic amino acid transporter, y+ system), member 50.290
Slc26a1solute carrier family 26 (sulfate transporter), member 10.267
Klf1Kruppel-like factor 1 (erythroid)0.250
Narsasparaginyl-tRNA synthetase0.245
Shmt2serine hydroxymethyltransferase 2 (mitochondrial)0.219
F13bcoagulation factor XIII, beta subunit0.177
Garsglycyl-tRNA synthetase0.165
Slc6a13solute carrier family 6 (neurotransmitter transporter, GABA), member 130.153
Hnf4ahepatic nuclear factor 4, alpha0.138
Slc40a1solute carrier family 40 (iron-regulated transporter), member 10.131
Timd2T-cell immunoglobulin and mucin domain containing 20.130
Apomapolipoprotein M0.121
Abcc6ATP-binding cassette, sub-family C (CFTR/MRP), member 60.113
Hsd3b4hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 40.102
Gjb1gap junction protein, beta 10.093
Pipoxpipecolic acid oxidase0.085
Hgdhomogentisate 1, 2-dioxygenase0.079
Nr1h4nuclear receptor subfamily 1, group H, member 40.079
Ppatphosphoribosyl pyrophosphate amidotransferase0.078
BC048355cDNA sequence BC0483550.072
Apoc1apolipoprotein C-I0.070
Iarsisoleucine-tRNA synthetase0.069
Bhmt2betaine-homocysteine methyltransferase 20.068
Tmem48transmembrane protein 480.067
Lrp2low density lipoprotein receptor-related protein 20.067
Unguracil DNA glycosylase0.066
Serpina6serine (or cysteine) peptidase inhibitor, clade A, member 60.064
Clcn2chloride channel 20.063
Cyp2d26cytochrome P450, family 2, subfamily d, polypeptide 260.063
Aadataminoadipate aminotransferase0.062
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.061
Gcgrglucagon receptor0.054
Sdslserine dehydratase-like0.050
Slc16a2solute carrier family 16 (monocarboxylic acid transporters), member 20.050
Yarstyrosyl-tRNA synthetase0.049
Prkar2aprotein kinase, cAMP dependent regulatory, type II alpha0.049
Gldcglycine decarboxylase0.046
Cyp2d10cytochrome P450, family 2, subfamily d, polypeptide 100.045
Kng1kininogen 10.044
Car5acarbonic anhydrase 5a, mitochondrial0.043
Cldn2claudin 20.042
1300017J02RikRIKEN cDNA 1300017J02 gene0.042
Prodh2proline dehydrogenase (oxidase) 20.041
F2coagulation factor II0.040
Umpsuridine monophosphate synthetase0.039
Procprotein C0.038
Mpzl2myelin protein zero-like 20.038
Masp2mannan-binding lectin serine peptidase 20.037
Slc22a2solute carrier family 22 (organic cation transporter), member 20.037
Pparaperoxisome proliferator activated receptor alpha0.037
Slc7a1solute carrier family 7 (cationic amino acid transporter, y+ system), member 10.037
Serpinf2serine (or cysteine) peptidase inhibitor, clade F, member 20.037
Slc2a2solute carrier family 2 (facilitated glucose transporter), member 20.036
Ero1lERO1-like (S. cerevisiae)0.035
Slc12a1solute carrier family 12, member 10.035
Dmgdhdimethylglycine dehydrogenase precursor0.035
Plgplasminogen0.034
Acy1aminoacylase 10.033
Pycr1pyrroline-5-carboxylate reductase 10.033
Sall1sal-like 1 (Drosophila)0.032
Itih1inter-alpha trypsin inhibitor, heavy chain 10.032
Gamtguanidinoacetate methyltransferase0.032
G6pcglucose-6-phosphatase, catalytic0.032
F7coagulation factor VII0.032
Ctpscytidine 5'-triphosphate synthase0.032
Orc2origin recognition complex, subunit 20.031
Cyp2a12cytochrome P450, family 2, subfamily a, polypeptide 120.031
Gcgroup specific component0.030
Onecut1one cut domain, family member 10.029
Rad51RAD51 homolog (S. cerevisiae)0.029
Cldn1claudin 10.029
Fpgsfolylpolyglutamyl synthetase0.029
Cidebcell death-inducing DNA fragmentation factor, alpha subunit-like effector B0.029
Larsleucyl-tRNA synthetase0.029
Exo1exonuclease 10.029
MgmtO-6-methylguanine-DNA methyltransferase0.028
Hsd3b6hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 60.027
Slc6a12solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 120.026
Serpina1cserine (or cysteine) peptidase inhibitor, clade A, member 1C0.026
Lama1laminin, alpha 10.025
Upp2uridine phosphorylase 20.025
Iydiodotyrosine deiodinase0.025
Tdo2tryptophan 2,3-dioxygenase0.024
Phgdh3-phosphoglycerate dehydrogenase0.024
Ttrtransthyretin0.024
Orc1origin recognition complex, subunit 10.024
Mcm10minichromosome maintenance deficient 10 (S. cerevisiae)0.024
Lhx1LIM homeobox protein 10.024
Cdc6cell division cycle 6 homolog (S. cerevisiae)0.024
Pde6bphosphodiesterase 6B, cGMP, rod receptor, beta polypeptide0.023
Gnmtglycine N-methyltransferase0.023
Slc3a1solute carrier family 3, member 10.023
Aldobaldolase B, fructose-bisphosphate0.023
Apoa2apolipoprotein A-II0.023
Clcnkachloride channel Ka0.023
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism