The network for 'negative regulation of inflammatory response to antigenic stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of inflammatory response to antigenic stimulus

Any process that stops, prevents, or reduces the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.

NameDescriptionProbabilityFunc Analog Organism
FauFinkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed0.066
Mrpl27mitochondrial ribosomal protein L270.046
RGD1304704similar to Hypothetical protein CGI-990.045
Ndufa2NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 20.041
Myeov2myeloma overexpressed 20.040
Rpl35ribosomal protein L350.039
LOC100361944hypothetical protein LOC1003619440.028
Rps17ribosomal protein S170.022
Cox5bcytochrome c oxidase subunit Vb0.022
Cycscytochrome c, somatic0.019
Rps8ribosomal protein S80.019
Psmb4proteasome (prosome, macropain) subunit, beta type 40.017
Atp5jATP synthase, H+ transporting, mitochondrial F0 complex, subunit F60.017
Rpl7aribosomal protein L7a0.015
Uqcrbubiquinol-cytochrome c reductase binding protein0.015
Mrps16mitochondrial ribosomal protein S160.014
Timm23translocase of inner mitochondrial membrane 23 homolog (yeast)0.013
Ndufb10NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 100.012
Ndufa13NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 130.011
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
HLA-DMAmajor histocompatibility complex, class II, DM alpha0.586
PSMB7proteasome (prosome, macropain) subunit, beta type, 70.199
PSMB1proteasome (prosome, macropain) subunit, beta type, 10.195
HLA-DPA1major histocompatibility complex, class II, DP alpha 10.136
HLA-DRAmajor histocompatibility complex, class II, DR alpha0.073
HLA-DRB1major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 10.068
HLA-DRB5major histocompatibility complex, class II, DR beta 50.031
HLA-DMBmajor histocompatibility complex, class II, DM beta0.025
POMPproteasome maturation protein0.024
PSMB5proteasome (prosome, macropain) subunit, beta type, 50.024
PSMB2proteasome (prosome, macropain) subunit, beta type, 20.016
CD74CD74 molecule, major histocompatibility complex, class II invariant chain0.013
PSMA7proteasome (prosome, macropain) subunit, alpha type, 70.013
DERL1Der1-like domain family, member 10.013
HLA-DPB1major histocompatibility complex, class II, DP beta 10.011
PSMA6proteasome (prosome, macropain) subunit, alpha type, 60.010
HLA-DRB4major histocompatibility complex, class II, DR beta 40.010
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Lyz2lysozyme 21.000
Tnftumor necrosis factor1.000
Tlr4toll-like receptor 41.000
Ifnginterferon gamma0.999
Rag1recombination activating gene 10.999
Cd44CD44 antigen0.998
Foxp3forkhead box P30.998
Fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.997
FasFas (TNF receptor superfamily member 6)0.996
Prf1perforin 1 (pore forming protein)0.993
LynYamaguchi sarcoma viral (v-yes-1) oncogene homolog0.993
Mmp9matrix metallopeptidase 90.984
Ccr1chemokine (C-C motif) receptor 10.981
Ptprcprotein tyrosine phosphatase, receptor type, C0.981
Il10interleukin 100.973
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.962
Il6interleukin 60.931
TcraT-cell receptor alpha chain0.926
Myd88myeloid differentiation primary response gene 880.907
Ccr2chemokine (C-C motif) receptor 20.906
Nos2nitric oxide synthase 2, inducible0.878
Il4interleukin 40.863
Itgb2integrin beta 20.854
Cd19CD19 antigen0.852
Inpp5dinositol polyphosphate-5-phosphatase D0.851
Ifngr1interferon gamma receptor 10.801
Nlrp3NLR family, pyrin domain containing 30.794
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.776
Il1r1interleukin 1 receptor, type I0.732
Apoeapolipoprotein E0.710
Il2interleukin 20.709
Ccl2chemokine (C-C motif) ligand 20.706
Il6stinterleukin 6 signal transducer0.659
Stat3signal transducer and activator of transcription 30.658
FaslFas ligand (TNF superfamily, member 6)0.647
TyrobpTYRO protein tyrosine kinase binding protein0.642
Casp1caspase 10.628
MefvMediterranean fever0.570
C1qbcomplement component 1, q subcomponent, beta polypeptide0.500
Casp4caspase 4, apoptosis-related cysteine peptidase0.499
Il1binterleukin 1 beta0.477
PycardPYD and CARD domain containing0.413
C3ar1complement component 3a receptor 10.368
Unc93b1unc-93 homolog B1 (C. elegans)0.368
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.353
Tlr2toll-like receptor 20.347
Emr1EGF-like module containing, mucin-like, hormone receptor-like sequence 10.334
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.333
Tgfb1transforming growth factor, beta 10.323
Il2rginterleukin 2 receptor, gamma chain0.323
Rag2recombination activating gene 20.306
C1qacomplement component 1, q subcomponent, alpha polypeptide0.305
Iqcb1IQ calmodulin-binding motif containing 10.269
C1qccomplement component 1, q subcomponent, C chain0.266
Clec4nC-type lectin domain family 4, member n0.238
Cxcr2chemokine (C-X-C motif) receptor 20.232
Foxn1forkhead box N10.227
Gpx1glutathione peroxidase 10.227
Csf1rcolony stimulating factor 1 receptor0.218
Ikzf1IKAROS family zinc finger 10.217
Col1a1collagen, type I, alpha 10.209
Hmox1heme oxygenase (decycling) 10.208
Psma3proteasome (prosome, macropain) subunit, alpha type 30.192
Spp1secreted phosphoprotein 10.165
Cd28CD28 antigen0.156
Ooepoocyte expressed protein homolog (dog)0.146
Tnip1TNFAIP3 interacting protein 10.137
Trem3triggering receptor expressed on myeloid cells 30.125
Pilrb1paired immunoglobin-like type 2 receptor beta 10.124
Nfe2l2nuclear factor, erythroid derived 2, like 20.116
Map3k14mitogen-activated protein kinase kinase kinase 140.110
Selpselectin, platelet0.100
Psma6proteasome (prosome, macropain) subunit, alpha type 60.099
Trp53transformation related protein 530.099
Msr1macrophage scavenger receptor 10.095
Fcgr2bFc receptor, IgG, low affinity IIb0.094
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.091
Il22interleukin 220.089
Cd14CD14 antigen0.086
Ms4a6dmembrane-spanning 4-domains, subfamily A, member 6D0.085
Il10rainterleukin 10 receptor, alpha0.085
Il27rainterleukin 27 receptor, alpha0.084
Stat6signal transducer and activator of transcription 60.084
Vdrvitamin D receptor0.084
Csf1colony stimulating factor 1 (macrophage)0.084
Cd68CD68 antigen0.082
Ccl9chemokine (C-C motif) ligand 90.079
Pik3cgphosphoinositide-3-kinase, catalytic, gamma polypeptide0.076
Ptgs2prostaglandin-endoperoxide synthase 20.074
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.074
Tnfaip8l2tumor necrosis factor, alpha-induced protein 8-like 20.068
Lyz1lysozyme 10.068
Aif1allograft inflammatory factor 10.066
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.066
Sfpi1SFFV proviral integration 10.065
Cd40CD40 antigen0.065
Mrc1mannose receptor, C type 10.065
Ctsscathepsin S0.064
Il23ainterleukin 23, alpha subunit p190.063
Irf1interferon regulatory factor 10.063
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism