IMP
Process View
The network for 'insulin secretion involved in cellular response to glucose stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
insulin secretion involved in cellular response to glucose stimulus
The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Rps5 | ribosomal protein S5 | 0.046 | |
| Rpl18a | ribosomal protein L18A | 0.035 | |
| Rps3 | ribosomal protein S3 | 0.031 | |
| Rpl10 | ribosomal protein L10 | 0.029 | |
| Rps26 | ribosomal protein S26 | 0.024 | |
| LOC100360491 | 60S ribosomal protein L13-like | 0.022 | |
| Rps17 | ribosomal protein S17 | 0.021 | |
| Rpl8 | ribosomal protein L8 | 0.020 | |
| Rplp1 | ribosomal protein, large, P1 | 0.020 | |
| Rpl10a | ribosomal protein L10A | 0.019 | |
| Rplp0 | ribosomal protein, large, P0 | 0.019 | |
| Uba52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | 0.017 | |
| Rpl18 | ribosomal protein L18 | 0.017 | |
| Rps9 | ribosomal protein S9 | 0.017 | |
| Rpsa | ribosomal protein SA | 0.017 | |
| Rps10 | ribosomal protein S10 | 0.016 | |
| Rps6 | ribosomal protein S6 | 0.016 | |
| Rps16 | ribosomal protein S16 | 0.016 | |
| LOC100362298 | ribosomal protein S18-like | 0.015 | |
| Gnb2l1 | guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 | 0.015 | |
| Rps27a | ribosomal protein S27a | 0.014 | |
| Rpl17 | ribosomal protein L17 | 0.014 | |
| Rpl11 | ribosomal protein L11 | 0.014 | |
| Rpl24 | ribosomal protein L24 | 0.014 | |
| Rpl19 | ribosomal protein L19 | 0.014 | |
| Rps2 | ribosomal protein S2 | 0.013 | |
| Rps4x | ribosomal protein S4, X-linked | 0.012 | |
| Psmb1 | proteasome (prosome, macropain) subunit, beta type 1 | 0.012 | |
| Rpl34 | ribosomal protein L34 | 0.012 | |
| Rpl37 | ribosomal protein L37 | 0.012 | |
| Rpl3 | ribosomal protein L3 | 0.012 | |
| Fau | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | 0.012 | |
| Rpl27a | ribosomal protein L27a | 0.012 | |
| LOC100360150 | eukaryotic translation elongation factor 1 alpha 2 | 0.012 | |
| Rpl7a | ribosomal protein L7a | 0.012 | |
| LOC100362751 | ribosomal protein P2-like | 0.011 | |
| Rpl4 | ribosomal protein L4 | 0.011 | |
| Rpl6 | ribosomal protein L6 | 0.011 | |
| Rpl23 | ribosomal protein L23 | 0.011 | |
| Rpl27 | ribosomal protein L27 | 0.011 | |
| Rpl28 | ribosomal protein L28 | 0.011 | |
| Rpl31 | ribosomal protein L31 | 0.011 | |
| Cox5b | cytochrome c oxidase subunit Vb | 0.010 | |
| Rpl5 | ribosomal protein L5 | 0.010 | |
| Psmb3 | proteasome (prosome, macropain) subunit, beta type 3 | 0.010 | |
| Rps7 | ribosomal protein S7 | 0.010 |
Loading network...
Homo sapiens| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| CCNY | cyclin Y | 0.141 | |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.087 | |
| VAMP3 | vesicle-associated membrane protein 3 (cellubrevin) | 0.081 | |
| HLA-DMB | major histocompatibility complex, class II, DM beta | 0.047 | |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.045 | |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.034 | |
| SNAP23 | synaptosomal-associated protein, 23kDa | 0.033 | |
| HLA-DRB5 | major histocompatibility complex, class II, DR beta 5 | 0.033 | |
| MPDZ | multiple PDZ domain protein | 0.031 | |
| NAPA | N-ethylmaleimide-sensitive factor attachment protein, alpha | 0.028 | |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 0.020 | |
| CRHR1 | corticotropin releasing hormone receptor 1 | 0.015 | |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 0.013 | |
| MAFA | v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) | 0.013 | |
| INCENP | inner centromere protein antigens 135/155kDa | 0.012 |
Loading network...
Mus musculus| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Efnb2 | ephrin B2 | 0.985 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.976 | |
| Pax2 | paired box gene 2 | 0.834 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.750 | |
| Rarg | retinoic acid receptor, gamma | 0.730 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.693 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.582 | |
| Nrxn1 | neurexin I | 0.555 | |
| Psen1 | presenilin 1 | 0.540 | |
| Pax8 | paired box gene 8 | 0.526 | |
| Epha4 | Eph receptor A4 | 0.482 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.457 | |
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.418 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.395 | |
| Nkx2-1 | NK2 homeobox 1 | 0.372 | |
| Ephb2 | Eph receptor B2 | 0.368 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.353 | |
| Fgf8 | fibroblast growth factor 8 | 0.352 | |
| Bmp4 | bone morphogenetic protein 4 | 0.346 | |
| Nrxn3 | neurexin III | 0.333 | |
| Ret | ret proto-oncogene | 0.314 | |
| Jag1 | jagged 1 | 0.298 | |
| LOC100048884 | novel member of the major urinary protein (Mup) gene family | 0.288 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.284 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.272 | |
| Gata4 | GATA binding protein 4 | 0.256 | |
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.242 | |
| Grin1 | glutamate receptor, ionotropic, NMDA1 (zeta 1) | 0.226 | |
| Lhx1 | LIM homeobox protein 1 | 0.224 | |
| Efnb1 | ephrin B1 | 0.206 | |
| Grid2 | glutamate receptor, ionotropic, delta 2 | 0.189 | |
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.174 | |
| Nf1 | neurofibromatosis 1 | 0.168 | |
| Dock1 | dedicator of cytokinesis 1 | 0.155 | |
| Cbln1 | cerebellin 1 precursor protein | 0.151 | |
| Pax3 | paired box gene 3 | 0.149 | |
| Tbx3 | T-box 3 | 0.141 | |
| Gnaq | guanine nucleotide binding protein, alpha q polypeptide | 0.135 | |
| Ldb3 | LIM domain binding 3 | 0.134 | |
| Foxa2 | forkhead box A2 | 0.132 | |
| Sox4 | SRY-box containing gene 4 | 0.127 | |
| Foxc2 | forkhead box C2 | 0.126 | |
| Nrxn2 | neurexin II | 0.123 | |
| Pim2 | proviral integration site 2 | 0.118 | |
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.113 | |
| Ephb3 | Eph receptor B3 | 0.112 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.111 | |
| Mup13 | major urinary protein 13 | 0.105 | |
| Thra | thyroid hormone receptor alpha | 0.102 | |
| Mup19 | major urinary protein 19 | 0.101 | |
| Pou3f2 | POU domain, class 3, transcription factor 2 | 0.097 | |
| Mup9 | major urinary protein 9 | 0.095 | |
| Src | Rous sarcoma oncogene | 0.093 | |
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.092 | |
| Smad6 | MAD homolog 6 (Drosophila) | 0.092 | |
| Mup10 | major urinary protein 10 | 0.090 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.089 | |
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.089 | |
| Fgf3 | fibroblast growth factor 3 | 0.088 | |
| Hoxa1 | homeobox A1 | 0.087 | |
| Mup7 | major urinary protein 7 | 0.084 | |
| Mapk3 | mitogen-activated protein kinase 3 | 0.084 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.082 | |
| Bsn | bassoon | 0.082 | |
| Prkaca | protein kinase, cAMP dependent, catalytic, alpha | 0.082 | |
| Ppp3r1 | protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) | 0.082 | |
| Prkce | protein kinase C, epsilon | 0.081 | |
| Mup1 | major urinary protein 1 | 0.080 | |
| Rxra | retinoid X receptor alpha | 0.080 | |
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.079 | |
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.078 | |
| Dlg1 | discs, large homolog 1 (Drosophila) | 0.077 | |
| Rdh10 | retinol dehydrogenase 10 (all-trans) | 0.077 | |
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.076 | |
| Shh | sonic hedgehog | 0.076 | |
| LOC100048885 | major urinary protein LOC100048885 | 0.075 | |
| Mup5 | major urinary protein 5 | 0.073 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.073 | |
| Coro1b | coronin, actin binding protein 1B | 0.072 | |
| Foxc1 | forkhead box C1 | 0.071 | |
| Mup17 | major urinary protein 17 | 0.070 | |
| Mapk8ip1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.069 | |
| Lrp5 | low density lipoprotein receptor-related protein 5 | 0.069 | |
| T | brachyury | 0.068 | |
| Ilk | integrin linked kinase | 0.065 | |
| Gpc3 | glypican 3 | 0.064 | |
| Gsk3b | glycogen synthase kinase 3 beta | 0.064 | |
| Epha5 | Eph receptor A5 | 0.063 | |
| Drd2 | dopamine receptor D2 | 0.063 | |
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.062 | |
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.061 | |
| Slc17a8 | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 | 0.061 | |
| Adam19 | a disintegrin and metallopeptidase domain 19 (meltrin beta) | 0.060 | |
| Thrb | thyroid hormone receptor beta | 0.060 | |
| Sox11 | SRY-box containing gene 11 | 0.060 | |
| Mup4 | major urinary protein 4 | 0.059 | |
| Nog | noggin | 0.057 | |
| Rarb | retinoic acid receptor, beta | 0.057 | |
| Amh | anti-Mullerian hormone | 0.057 | |
| Sema6a | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.057 |