The network for 'insulin secretion involved in cellular response to glucose stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

insulin secretion involved in cellular response to glucose stimulus

The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus.

NameDescriptionProbabilityFunc Analog Organism
Rps5ribosomal protein S50.046
Rpl18aribosomal protein L18A0.035
Rps3ribosomal protein S30.031
Rpl10ribosomal protein L100.029
Rps26ribosomal protein S260.024
LOC10036049160S ribosomal protein L13-like0.022
Rps17ribosomal protein S170.021
Rpl8ribosomal protein L80.020
Rplp1ribosomal protein, large, P10.020
Rpl10aribosomal protein L10A0.019
Rplp0ribosomal protein, large, P00.019
Uba52ubiquitin A-52 residue ribosomal protein fusion product 10.017
Rpl18ribosomal protein L180.017
Rps9ribosomal protein S90.017
Rpsaribosomal protein SA0.017
Rps10ribosomal protein S100.016
Rps6ribosomal protein S60.016
Rps16ribosomal protein S160.016
LOC100362298ribosomal protein S18-like0.015
Gnb2l1guanine nucleotide binding protein (G protein), beta polypeptide 2 like 10.015
Rps27aribosomal protein S27a0.014
Rpl17ribosomal protein L170.014
Rpl11ribosomal protein L110.014
Rpl24ribosomal protein L240.014
Rpl19ribosomal protein L190.014
Rps2ribosomal protein S20.013
Rps4xribosomal protein S4, X-linked0.012
Psmb1proteasome (prosome, macropain) subunit, beta type 10.012
Rpl34ribosomal protein L340.012
Rpl37ribosomal protein L370.012
Rpl3ribosomal protein L30.012
FauFinkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed0.012
Rpl27aribosomal protein L27a0.012
LOC100360150eukaryotic translation elongation factor 1 alpha 20.012
Rpl7aribosomal protein L7a0.012
LOC100362751ribosomal protein P2-like0.011
Rpl4ribosomal protein L40.011
Rpl6ribosomal protein L60.011
Rpl23ribosomal protein L230.011
Rpl27ribosomal protein L270.011
Rpl28ribosomal protein L280.011
Rpl31ribosomal protein L310.011
Cox5bcytochrome c oxidase subunit Vb0.010
Rpl5ribosomal protein L50.010
Psmb3proteasome (prosome, macropain) subunit, beta type 30.010
Rps7ribosomal protein S70.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CCNYcyclin Y0.141
SNAP25synaptosomal-associated protein, 25kDa0.087
VAMP3vesicle-associated membrane protein 3 (cellubrevin)0.081
HLA-DMBmajor histocompatibility complex, class II, DM beta0.047
HLA-DQA1major histocompatibility complex, class II, DQ alpha 10.045
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.034
SNAP23synaptosomal-associated protein, 23kDa0.033
HLA-DRB5major histocompatibility complex, class II, DR beta 50.033
MPDZmultiple PDZ domain protein0.031
NAPAN-ethylmaleimide-sensitive factor attachment protein, alpha0.028
HLA-DRAmajor histocompatibility complex, class II, DR alpha0.020
CRHR1corticotropin releasing hormone receptor 10.015
HLA-DMAmajor histocompatibility complex, class II, DM alpha0.013
MAFAv-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)0.013
INCENPinner centromere protein antigens 135/155kDa0.012
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Efnb2ephrin B20.985
Gli3GLI-Kruppel family member GLI30.976
Pax2paired box gene 20.834
Ctnnb1catenin (cadherin associated protein), beta 10.750
Rargretinoic acid receptor, gamma0.730
Fgfr2fibroblast growth factor receptor 20.693
Eya1eyes absent 1 homolog (Drosophila)0.582
Nrxn1neurexin I0.555
Psen1presenilin 10.540
Pax8paired box gene 80.526
Epha4Eph receptor A40.482
Fgfr1fibroblast growth factor receptor 10.457
Pbx1pre B-cell leukemia transcription factor 10.418
Lef1lymphoid enhancer binding factor 10.395
Nkx2-1NK2 homeobox 10.372
Ephb2Eph receptor B20.368
Ptpn11protein tyrosine phosphatase, non-receptor type 110.353
Fgf8fibroblast growth factor 80.352
Bmp4bone morphogenetic protein 40.346
Nrxn3neurexin III0.333
Retret proto-oncogene0.314
Jag1jagged 10.298
LOC100048884novel member of the major urinary protein (Mup) gene family0.288
Pitx2paired-like homeodomain transcription factor 20.284
Tgfb2transforming growth factor, beta 20.272
Gata4GATA binding protein 40.256
Hey2hairy/enhancer-of-split related with YRPW motif 20.242
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.226
Lhx1LIM homeobox protein 10.224
Efnb1ephrin B10.206
Grid2glutamate receptor, ionotropic, delta 20.189
Bcl2B-cell leukemia/lymphoma 20.174
Nf1neurofibromatosis 10.168
Dock1dedicator of cytokinesis 10.155
Cbln1cerebellin 1 precursor protein0.151
Pax3paired box gene 30.149
Tbx3T-box 30.141
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.135
Ldb3LIM domain binding 30.134
Foxa2forkhead box A20.132
Sox4SRY-box containing gene 40.127
Foxc2forkhead box C20.126
Nrxn2neurexin II0.123
Pim2proviral integration site 20.118
Hes1hairy and enhancer of split 1 (Drosophila)0.113
Ephb3Eph receptor B30.112
Nos3nitric oxide synthase 3, endothelial cell0.111
Mup13major urinary protein 130.105
Thrathyroid hormone receptor alpha0.102
Mup19major urinary protein 190.101
Pou3f2POU domain, class 3, transcription factor 20.097
Mup9major urinary protein 90.095
SrcRous sarcoma oncogene0.093
Nr3c1nuclear receptor subfamily 3, group C, member 10.092
Smad6MAD homolog 6 (Drosophila)0.092
Mup10major urinary protein 100.090
Vangl2vang-like 2 (van gogh, Drosophila)0.089
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.089
Fgf3fibroblast growth factor 30.088
Hoxa1homeobox A10.087
Mup7major urinary protein 70.084
Mapk3mitogen-activated protein kinase 30.084
Fgfr3fibroblast growth factor receptor 30.082
Prkacaprotein kinase, cAMP dependent, catalytic, alpha0.082
Ppp3r1protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)0.082
Prkceprotein kinase C, epsilon0.081
Mup1major urinary protein 10.080
Rxraretinoid X receptor alpha0.080
Itgb1integrin beta 1 (fibronectin receptor beta)0.079
Notch1Notch gene homolog 1 (Drosophila)0.078
Dlg1discs, large homolog 1 (Drosophila)0.077
Rdh10retinol dehydrogenase 10 (all-trans)0.077
Hif1ahypoxia inducible factor 1, alpha subunit0.076
Shhsonic hedgehog0.076
LOC100048885major urinary protein LOC1000488850.075
Mup5major urinary protein 50.073
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.073
Coro1bcoronin, actin binding protein 1B0.072
Foxc1forkhead box C10.071
Mup17major urinary protein 170.070
Mapk8ip1mitogen-activated protein kinase 8 interacting protein 10.069
Lrp5low density lipoprotein receptor-related protein 50.069
Ilkintegrin linked kinase0.065
Gpc3glypican 30.064
Gsk3bglycogen synthase kinase 3 beta0.064
Epha5Eph receptor A50.063
Drd2dopamine receptor D20.063
Otx1orthodenticle homolog 1 (Drosophila)0.062
Lrp6low density lipoprotein receptor-related protein 60.061
Slc17a8solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 80.061
Adam19a disintegrin and metallopeptidase domain 19 (meltrin beta)0.060
Thrbthyroid hormone receptor beta0.060
Sox11SRY-box containing gene 110.060
Mup4major urinary protein 40.059
Rarbretinoic acid receptor, beta0.057
Amhanti-Mullerian hormone0.057
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.057
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism