The network for 'glomerular filtration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

glomerular filtration

The process in which plasma is filtered through the glomerular membrane which consists of capillary endothelial cells, the basement membrane, and epithelial cells. The glomerular filtrate is the same as plasma except it has no significant amount of protein.

NameDescriptionProbabilityFunc Analog Organism
Ptafrplatelet-activating factor receptor0.351
Serpine2serine (or cysteine) peptidase inhibitor, clade E, member 20.285
Gja5gap junction protein, alpha 50.247
Gfapglial fibrillary acidic protein0.124
Nrg1neuregulin 10.115
Tff1trefoil factor 10.081
Marcksmyristoylated alanine rich protein kinase C substrate0.068
Vdrvitamin D (1,25- dihydroxyvitamin D3) receptor0.066
Ednraendothelin receptor type A0.062
S1pr2sphingosine-1-phosphate receptor 20.056
Ptgfrprostaglandin F receptor0.048
Cyp21a1cytochrome P450, family 21, subfamily a, polypeptide 10.047
Il1ainterleukin 1 alpha0.040
Tnfrsf4tumor necrosis factor receptor superfamily, member 40.036
Gnb4guanine nucleotide binding protein (G protein), beta polypeptide 40.036
Olr287olfactory receptor 2870.035
Prss22protease, serine, 220.035
Fcgr3aFc fragment of IgG, low affinity IIIa, receptor0.031
Nraddneurotrophin receptor associated death domain0.030
Magmyelin-associated glycoprotein0.029
Cd83CD83 molecule0.028
Acvrl1activin A receptor type II-like 10.026
Igfbp5insulin-like growth factor binding protein 50.025
Dock8dedicator of cytokinesis 80.025
Esamendothelial cell adhesion molecule0.024
Tcf4transcription factor 40.020
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.020
Sfrp4secreted frizzled-related protein 40.019
Vcanversican0.019
Prkchprotein kinase C, eta0.018
Wwtr1WW domain containing transcription regulator 10.018
Slc1a3solute carrier family 1 (glial high affinity glutamate transporter), member 30.018
Pspparotid secretory protein0.018
Itga6integrin, alpha 60.017
Atp4aATPase, H+/K+ exchanging, alpha polypeptide0.017
Gnrhrgonadotropin releasing hormone receptor0.017
Rhojras homolog gene family, member J0.016
Dnah2dynein, axonemal, heavy chain 20.016
Atxn1ataxin 10.015
Olfml2bolfactomedin-like 2B0.015
Thbdthrombomodulin0.015
Stra6stimulated by retinoic acid gene 60.015
Ppap2bphosphatidic acid phosphatase type 2B0.015
Vom2r27vomeronasal 2 receptor, 270.015
Slc7a2solute carrier family 7 (cationic amino acid transporter, y+ system), member 20.015
Cst12cystatin 120.014
Serinc5serine incorporator 50.014
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.014
Olr1469olfactory receptor Olr14690.014
Sirpasignal-regulatory protein alpha0.013
Efnb1ephrin B10.013
Colqcollagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase0.013
Padi1peptidyl arginine deiminase, type I0.013
Fgf2fibroblast growth factor 20.013
Ctnnd1catenin (cadherin associated protein), delta 10.013
Tnftumor necrosis factor (TNF superfamily, member 2)0.013
Cgaglycoprotein hormones, alpha polypeptide0.013
Akap12A kinase (PRKA) anchor protein 120.013
Podxlpodocalyxin-like0.013
Eaf1ELL associated factor 10.013
Dll3delta-like 3 (Drosophila)0.013
Fam70bfamily with sequence similarity 70, member B0.013
Scn7asodium channel, voltage-gated, type VII, alpha0.012
F2rl1coagulation factor II (thrombin) receptor-like 10.012
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.012
Strnstriatin, calmodulin binding protein0.012
Ptk7PTK7 protein tyrosine kinase 70.011
Prp15proline-rich protein 150.011
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.011
Sstr4somatostatin receptor 40.011
Trhthyrotropin releasing hormone0.011
Olr226olfactory receptor 2260.011
Pde5aphosphodiesterase 5A, cGMP-specific0.011
Lypd3Ly6/Plaur domain containing 30.011
Opn1mwopsin 1 (cone pigments), medium-wave-sensitive0.010
Aqp4aquaporin 40.010
Slc44a4solute carrier family 44, member 40.010
Olr1701olfactory receptor 17010.010
Socs3suppressor of cytokine signaling 30.010
Csf1colony stimulating factor 1 (macrophage)0.010
Nos3nitric oxide synthase 3, endothelial cell0.010
Sult5a1sulfotransferase family 5A, member 10.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
etv2ets variant gene 20.299
podxlpodocalyxin-like0.195
sulf1sulfatase 10.141
sulf2lsulfatase 2, like0.103
crb3bcrumbs homolog 3b0.100
crb2bcrumbs homolog 2b0.090
nr2f1anuclear receptor subfamily 2, group F, member 1a0.069
epb41l5erythrocyte membrane protein band 4.1 like 50.059
nphs2nephrosis 2, idiopathic, steroid-resistant (podocin)0.046
f2rcoagulation factor II (thrombin) receptor0.045
crb3acrumbs homolog 3a0.035
smchd1structural maintenance of chromosomes flexible hinge domain containing 10.033
wt1bwilms tumor 1b0.027
crb2acrumbs homolog 2a0.027
rykreceptor-like tyrosine kinase0.025
jam2bjunctional adhesion molecule 2b0.025
vegfabvascular endothelial growth factor Ab0.025
lrp2low density lipoprotein-related protein 20.024
sfrp2secreted frizzled-related protein 20.023
st14asuppression of tumorigenicity 14 (colon carcinoma) a0.022
crb1crumbs homolog 1 (Drosophila)0.020
ift88intraflagellar transport 88 homolog0.020
aqp8a.1aquaporin 8a, tandem duplicate 10.019
pde6cphosphodiesterase 6C, cGMP-specific, cone, alpha prime0.018
kif17kinesin family member 170.018
tcf12transcription factor 120.018
dtngdystrobrevin, gamma and dystrobrevin, gamma-like0.017
dnmt8DNA (cytosine-5-)-methyltransferase 80.017
vsg1vessel-specific 10.014
tjp2atight junction protein 2a (zona occludens 2)0.014
grk7aG-protein-coupled receptor kinase 7a0.013
col5a1procollagen, type V, alpha 10.012
fzd7afrizzled homolog 7a0.012
ahr2aryl hydrocarbon receptor 20.012
myocmyocilin0.011
cplx4acomplexin 4a0.011
f2rl1.2coagulation factor II (thrombin) receptor-like 1.20.011
kdrlkinase insert domain receptor like0.011
hapln1ahyaluronan and proteoglycan link protein 1a0.010
si:ch211-235f6.2si:ch211-235f6.20.010
zgc:63721zgc:637210.010
jag1ajagged 1a0.010
wtipWilms tumor 1 interacting protein0.010
slc4a1asolute carrier family 4, anion exchanger, member 1a0.010
colec11collectin sub-family member 110.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
AXLAXL receptor tyrosine kinase0.289
CAV1caveolin 1, caveolae protein, 22kDa0.049
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.035
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.023
COL4A1collagen, type IV, alpha 10.018
DPYSL4dihydropyrimidinase-like 40.015
COL5A1collagen, type V, alpha 10.012
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Nos3nitric oxide synthase 3, endothelial cell0.169
Kdrkinase insert domain protein receptor0.126
Ece1endothelin converting enzyme 10.102
Flt4FMS-like tyrosine kinase 40.097
Tgfb2transforming growth factor, beta 20.073
Flt1FMS-like tyrosine kinase 10.071
Nphs2nephrosis 2 homolog, podocin (human)0.067
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.059
Ush1cUsher syndrome 1C homolog (human)0.054
Fgfr1fibroblast growth factor receptor 10.053
Acvr1activin A receptor, type 10.051
Nrp1neuropilin 10.047
Trpv1transient receptor potential cation channel, subfamily V, member 10.045
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.042
Plxnd1plexin D10.039
Ush1gUsher syndrome 1G homolog (human)0.037
Epas1endothelial PAS domain protein 10.034
Ren1renin 1 structural0.032
Prrx1paired related homeobox 10.031
Wt1Wilms tumor 1 homolog0.029
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.029
Foxc2forkhead box C20.025
Cd151CD151 antigen0.025
Fzd4frizzled homolog 4 (Drosophila)0.024
Acvrl1activin A receptor, type II-like 10.023
Grxcr1glutaredoxin, cysteine rich 10.020
Ltbp1latent transforming growth factor beta binding protein 10.019
Myo15myosin XV0.019
Vclvinculin0.018
Pcdh15protocadherin 150.016
Whrnwhirlin0.015
Tbx1T-box 10.015
Notch2Notch gene homolog 2 (Drosophila)0.015
Thbdthrombomodulin0.014
Fgfr2fibroblast growth factor receptor 20.013
Phldb2pleckstrin homology-like domain, family B, member 20.013
Pdgfbplatelet derived growth factor, B polypeptide0.013
Wwtr1WW domain containing transcription regulator 10.013
Lmnalamin A0.012
Tinagl1tubulointerstitial nephritis antigen-like 10.012
Tgfbr2transforming growth factor, beta receptor II0.012
Col4a3collagen, type IV, alpha 30.012
Gata6GATA binding protein 60.011
Myo7amyosin VIIA0.011
Mkl2MKL/myocardin-like 20.011
Wwc2WW, C2 and coiled-coil domain containing 20.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism