The network for 'gland development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

gland development

The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion.

NameDescriptionProbabilityFunc Analog Organism
Metmet proto-oncogene0.914
Cyp2a1cytochrome P450, family 2, subfamily a, polypeptide 10.901
Bcl2B-cell CLL/lymphoma 20.885
Ech1enoyl coenzyme A hydratase 1, peroxisomal0.795
Decr12,4-dienoyl CoA reductase 1, mitochondrial0.748
Otcornithine carbamoyltransferase0.725
Ptprqprotein tyrosine phosphatase, receptor type, Q0.708
Fabp1fatty acid binding protein 1, liver0.700
Plauplasminogen activator, urokinase0.551
Slco2a1solute carrier organic anion transporter family, member 2a10.551
Mug1murinoglobulin 10.531
Chrm1cholinergic receptor, muscarinic 10.526
Acadlacyl-Coenzyme A dehydrogenase, long-chain0.507
Acaa2acetyl-Coenzyme A acyltransferase 20.474
Gata6GATA binding protein 60.468
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.457
Ugt2b5UDP glucuronosyltransferase 2 family, polypeptide B50.447
Ceacam1carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)0.425
Prrx1paired related homeobox 10.419
Apobapolipoprotein B0.394
Htr1d5-hydroxytryptamine (serotonin) receptor 1D0.392
Sardhsarcosine dehydrogenase0.391
Tgfbr2transforming growth factor, beta receptor II0.364
Agxt2alanine-glyoxylate aminotransferase 20.362
Mbl2mannose-binding lectin (protein C) 20.353
Sod3superoxide dismutase 3, extracellular0.352
Smad7SMAD family member 70.351
Il13interleukin 130.337
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.335
C8bcomplement component 8, beta polypeptide0.335
Icam1intercellular adhesion molecule 10.333
Tpsb2tryptase beta 20.326
Ppp1r3bprotein phosphatase 1, regulatory (inhibitor) subunit 3B0.325
Erbb4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.315
RT1-EC2RT1 class Ib, locus EC20.314
Apoa2apolipoprotein A-II0.313
Mapk4mitogen-activated protein kinase 40.306
Cd44Cd44 molecule0.304
Cyp2b3cytochrome P450, family 2, subfamily b, polypeptide 30.299
Aldobaldolase B, fructose-bisphosphate0.295
Fgfr1Fibroblast growth factor receptor 10.293
Ces2ccarboxylesterase 2C0.293
Foxa3forkhead box A30.290
Igfbp5insulin-like growth factor binding protein 50.287
Gna15guanine nucleotide binding protein, alpha 150.287
Cd4Cd4 molecule0.285
Cyp4a2cytochrome P450, family 4, subfamily a, polypeptide 20.281
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.267
Uoxurate oxidase0.266
Slc5a1solute carrier family 5 (sodium/glucose cotransporter), member 10.266
Chrna7cholinergic receptor, nicotinic, alpha 70.261
Gcgroup specific component0.260
Dpep1dipeptidase 1 (renal)0.260
Svs4seminal vesicle secretory protein 40.259
Sult1b1sulfotransferase family, cytosolic, 1B, member 10.258
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.258
Tacr1tachykinin receptor 10.257
Tgfbr3transforming growth factor, beta receptor III0.256
Pzppregnancy-zone protein0.256
Kmokynurenine 3-monooxygenase (kynurenine 3-hydroxylase)0.254
Serpind1serpin peptidase inhibitor, clade D (heparin cofactor), member 10.239
Etfdhelectron-transferring-flavoprotein dehydrogenase0.236
B4galt1UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 10.235
Nr2f6nuclear receptor subfamily 2, group F, member 60.233
Pik3c2gphosphoinositide-3-kinase, class 2, gamma polypeptide0.233
Rararetinoic acid receptor, alpha0.230
Bmp7bone morphogenetic protein 70.228
Ces1ccarboxylesterase 1C0.226
Gja5gap junction protein, alpha 50.225
Lipclipase, hepatic0.216
Gdf10growth differentiation factor 100.215
Ugt1a7cUDP glucuronosyltransferase 1 family, polypeptide A7C0.213
Ugt2b37UDP-glucuronosyltransferase 2 family, member 370.212
Eif4ebp1eukaryotic translation initiation factor 4E binding protein 10.211
Cyp2d2cytochrome P450, family 2, subfamily d, polypeptide 20.211
Miamelanoma inhibitory activity0.209
Olr1493olfactory receptor gene Olr14930.208
Cybbcytochrome b-245, beta polypeptide0.205
Igfalsinsulin-like growth factor binding protein, acid labile subunit0.204
Ctdsp1CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 10.201
Errfi1ERBB receptor feedback inhibitor 10.200
Fbp1fructose-1,6-bisphosphatase 10.199
Il12binterleukin 12B0.198
Krt5keratin 50.196
Nr5a2nuclear receptor subfamily 5, group A, member 20.195
Ghrhrgrowth hormone releasing hormone receptor0.192
Hsd17b10hydroxysteroid (17-beta) dehydrogenase 100.188
Agtr1aangiotensin II receptor, type 1a0.187
Unc5bunc-5 homolog B (C. elegans)0.187
G6pcglucose-6-phosphatase, catalytic subunit0.186
Rhobras homolog gene family, member B0.185
Col12a1collagen, type XII, alpha 10.185
Cyp2b2cytochrome P450, family 2, subfamily b, polypeptide 20.182
Amhanti-Mullerian hormone0.181
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
fgf3fibroblast growth factor 30.994
tbx1T-box 10.992
kdrlkinase insert domain receptor like0.983
hnf1baHNF1 homeobox Ba0.983
six3bsine oculis homeobox homolog 3b0.981
bmp2abone morphogenetic protein 2a0.966
jag2jagged 20.962
tp53tumor protein p530.955
flhfloating head0.952
ascl1aachaete-scute complex-like 1a (Drosophila)0.947
gli1GLI-Kruppel family member 10.946
shhasonic hedgehog a0.945
hhexhematopoietically expressed homeobox0.934
crabp2acellular retinoic acid binding protein 2, a0.904
eya1eyes absent homolog 10.900
fgf8afibroblast growth factor 8 a0.886
smosmoothened homolog (Drosophila)0.874
bmp2bbone morphogenetic protein 2b0.863
pax6bpaired box gene 6b0.861
foxa2forkhead box A20.857
tbx2bT-box 2b0.857
sox9bSRY-box containing gene 9b0.854
fn1fibronectin 10.834
rx3retinal homeobox gene 30.827
pcdh8protocadherin 80.821
dkk1bdickkopf 1b0.817
evx1even-skipped homeobox 10.809
gata4GATA-binding protein 40.802
gata3GATA-binding protein 30.798
nrp2bneuropilin 2b0.768
foxa1forkhead box A10.763
lhx2bLIM homeobox 2b0.761
mibmind bomb0.753
shhbsonic hedgehog b0.752
pitx2paired-like homeodomain transcription factor 20.733
wnt2bbwingless-type MMTV integration site family, member 2Bb0.718
gata6GATA-binding protein 60.695
itgavintegrin, alpha V0.679
efnb2aephrin B2a0.677
jag1bjagged 1b0.675
ndr2nodal-related 20.671
pcnaproliferating cell nuclear antigen0.664
bocbrother of CDO0.664
wnt3wingless-type MMTV integration site family, member 30.663
fzd7afrizzled homolog 7a0.655
wnt5bwingless-type MMTV integration site family, member 5b0.649
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.643
hey1hairy/enhancer-of-split related with YRPW motif 10.626
ikzf1IKAROS family zinc finger 1 (Ikaros)0.620
pax2apaired box gene 2a0.617
notch1anotch homolog 1a0.617
tp63tumor protein p630.615
gata5GATA-binding protein 50.614
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.597
ptgs2aprostaglandin-endoperoxide synthase 2a0.590
foxj1bforkhead box J1b0.577
sox2SRY-box containing gene 20.571
spry4sprouty (Drosophila) homolog 40.561
sfrp1asecreted frizzled-related protein 1a0.557
gli2aGLI-Kruppel family member GLI2a0.556
cdh1cadherin 1, epithelial0.554
foxi1forkhead box I10.552
tcf7transcription factor 7 (T-cell specific, HMG-box)0.551
sox9aSRY-box containing gene 9a0.538
tshbthyroid stimulating hormone, beta subunit0.527
metmet proto-oncogene (hepatocyte growth factor receptor)0.516
nanos3nanos homolog 30.516
dlx3bdistal-less homeobox gene 3b0.513
cxcl12bchemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)0.510
otpborthopedia homolog b0.507
sox10SRY-box containing gene 100.504
mitfamicrophthalmia-associated transcription factor a0.503
rargaretinoic acid receptor gamma a0.496
msxcmuscle segment homeobox C0.495
znf503zinc finger protein 5030.492
ephb4beph receptor B4b0.484
pitx3paired-like homeodomain transcription factor 30.481
hbbe3hemoglobin beta embryonic-30.480
fzd8afrizzled homolog 8a0.465
vax2ventral anterior homeobox 20.464
dlx5adistal-less homeobox gene 5a0.462
notch2notch homolog 20.455
otx5orthodenticle homolog 50.453
foxa3forkhead box A30.452
alcamaactivated leukocyte cell adhesion molecule a0.451
nr2f5nuclear receptor subfamily 2, group F, member 50.451
her6hairy-related 60.443
ldb2aLIM-domain binding factor 2a0.439
il17rdinterleukin 17 receptor D0.439
lmx1b.1LIM homeobox transcription factor 1, beta 10.436
raraaretinoic acid receptor, alpha a0.432
snai1bsnail homolog 1b (Drosophila)0.431
nog2noggin 20.426
cdh5cadherin 50.425
foxe3forkhead box E30.424
hoxa2bhomeo box A2b0.423
plagl2pleiomorphic adenoma gene-like 20.420
gdf6agrowth differentiation factor 6a0.414
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
MadMothers against dpp0.993
Stat92ESignal-transducer and activator of transcription protein at 92E0.976
EcREcdysone receptor0.945
Atg1Autophagy-specific gene 10.942
PtenCG5671 gene product from transcript CG5671-RB0.933
cicubitus interruptus0.921
E(spl)Enhancer of split0.893
abd-Aabdominal A0.804
slp1sloppy paired 10.768
Su(H)Suppressor of Hairless0.757
jingCG9397 gene product from transcript CG9397-RI0.748
Cdc42CG12530 gene product from transcript CG12530-RA0.683
ik2IkappaB kinase-like 20.626
TorTarget of rapamycin0.626
Ras85DRas oncogene at 85D0.624
HLHmdeltaE(spl) region transcript mdelta0.622
rapretina aberrant in pattern0.621
snssticks and stones0.613
gcmglial cells missing0.581
EgfrEpidermal growth factor receptor0.576
fz2frizzled 20.566
ftz-f1ftz transcription factor 10.566
slmbsupernumerary limbs0.559
eastenhanced adult sensory threshold0.543
HLHmbetaE(spl) region transcript mbeta0.534
mewmultiple edematous wings0.532
RalaRas-related protein0.527
Pi3K92ECG4141 gene product from transcript CG4141-RB0.514
Wnt5Wnt oncogene analog 50.511
RpS29Ribosomal protein S290.500
Fmr1CG6203 gene product from transcript CG6203-RC0.499
wbwing blister0.498
Rac1CG2248 gene product from transcript CG2248-RA0.496
Akt1CG4006 gene product from transcript CG4006-RA0.485
B52CG10851 gene product from transcript CG10851-RB0.461
HLHm7E(spl) region transcript m70.456
par-1CG8201 gene product from transcript CG8201-RA0.450
zfh1Zn finger homeodomain 10.443
sqhspaghetti squash0.430
Unc-76CG3981 gene product from transcript CG3981-RB0.416
Src42ASrc oncogene at 42A0.415
PvrPDGF- and VEGF-receptor related0.410
MED24Mediator complex subunit 240.407
SmoxSmad on X0.399
Grasp65CG7809 gene product from transcript CG7809-RA0.391
HLHmgammaE(spl) region transcript mgamma0.383
LanB2Laminin B20.364
vvlventral veins lacking0.357
TomTwin of m40.346
DadDaughters against dpp0.346
eveeven skipped0.342
CG14869CG14869 gene product from transcript CG14869-RB0.340
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ESR1estrogen receptor 10.999
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.995
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.986
EP300E1A binding protein p3000.985
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.983
ARandrogen receptor0.977
EGFRepidermal growth factor receptor0.974
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.956
FLNAfilamin A, alpha0.952
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.951
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.930
SMAD2SMAD family member 20.928
FN1fibronectin 10.918
FGFR2fibroblast growth factor receptor 20.893
DAXXdeath-domain associated protein0.870
TP53tumor protein p530.866
JAG1jagged 10.851
INSRinsulin receptor0.745
CREBBPCREB binding protein0.733
PTPN1protein tyrosine phosphatase, non-receptor type 10.731
CCNE1cyclin E10.728
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.706
FGFR1fibroblast growth factor receptor 10.706
BRCA1breast cancer 1, early onset0.682
TAL1T-cell acute lymphocytic leukemia 10.678
NOTCH1notch 10.660
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.652
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.650
DVL3dishevelled, dsh homolog 3 (Drosophila)0.618
MDM2Mdm2 p53 binding protein homolog (mouse)0.612
BBS10Bardet-Biedl syndrome 100.562
PAX3paired box 30.554
MYOD1myogenic differentiation 10.534
PSEN1presenilin 10.505
METmet proto-oncogene (hepatocyte growth factor receptor)0.488
NCOA1nuclear receptor coactivator 10.475
SMAD1SMAD family member 10.472
RARAretinoic acid receptor, alpha0.470
HNF4Ahepatocyte nuclear factor 4, alpha0.469
BMP2bone morphogenetic protein 20.452
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.449
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.437
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.419
GATA4GATA binding protein 40.417
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.415
CDK2cyclin-dependent kinase 20.412
POU3F2POU class 3 homeobox 20.390
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.390
NOTCH3notch 30.386
NR4A1nuclear receptor subfamily 4, group A, member 10.376
SMAD4SMAD family member 40.372
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.366
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.330
BCL2B-cell CLL/lymphoma 20.328
NCOA3nuclear receptor coactivator 30.323
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.305
THBS1thrombospondin 10.297
FHL2four and a half LIM domains 20.284
COL2A1collagen, type II, alpha 10.277
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.273
IGF1Rinsulin-like growth factor 1 receptor0.273
PMLpromyelocytic leukemia0.271
CDX2caudal type homeobox 20.263
NCOA2nuclear receptor coactivator 20.255
E2F8E2F transcription factor 80.253
SMAD7SMAD family member 70.252
NRP1neuropilin 10.249
PTPRCprotein tyrosine phosphatase, receptor type, C0.249
SOX2SRY (sex determining region Y)-box 20.243
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.243
RXRAretinoid X receptor, alpha0.239
RBPMSRNA binding protein with multiple splicing0.236
FOXA2forkhead box A20.236
SYKspleen tyrosine kinase0.234
VEGFAvascular endothelial growth factor A0.232
HOXB5homeobox B50.230
TBX2T-box 20.229
PKD2polycystic kidney disease 2 (autosomal dominant)0.223
E2F7E2F transcription factor 70.221
HSPG2heparan sulfate proteoglycan 20.218
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.215
NCOA6nuclear receptor coactivator 60.210
VDRvitamin D (1,25- dihydroxyvitamin D3) receptor0.210
FGF1fibroblast growth factor 1 (acidic)0.208
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.206
DDIT3DNA-damage-inducible transcript 30.204
TBX5T-box 50.197
EGR1early growth response 10.195
TCF4transcription factor 40.191
HOXA11homeobox A110.183
KAT2BK(lysine) acetyltransferase 2B0.180
PDX1pancreatic and duodenal homeobox 10.173
HOXA10homeobox A100.164
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.155
HIC1hypermethylated in cancer 10.154
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.154
LCKlymphocyte-specific protein tyrosine kinase0.153
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Fgfr2fibroblast growth factor receptor 21.000
Shhsonic hedgehog1.000
Lhx3LIM homeobox protein 31.000
Ptenphosphatase and tensin homolog1.000
Pax2paired box gene 21.000
Pax8paired box gene 81.000
Sox2SRY-box containing gene 21.000
Egfrepidermal growth factor receptor1.000
Pitx2paired-like homeodomain transcription factor 20.999
Trp63transformation related protein 630.999
Vangl2vang-like 2 (van gogh, Drosophila)0.999
Fgfr1fibroblast growth factor receptor 10.999
Gli3GLI-Kruppel family member GLI30.999
Rargretinoic acid receptor, gamma0.999
Arandrogen receptor0.998
Drd2dopamine receptor D20.998
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.998
Otx2orthodenticle homolog 2 (Drosophila)0.997
Rxraretinoid X receptor alpha0.997
Gli2GLI-Kruppel family member GLI20.996
Nr5a1nuclear receptor subfamily 5, group A, member 10.996
Esr1estrogen receptor 1 (alpha)0.995
Gata3GATA binding protein 30.995
Trp53transformation related protein 530.995
Notch1Notch gene homolog 1 (Drosophila)0.995
Hes1hairy and enhancer of split 1 (Drosophila)0.994
Vegfavascular endothelial growth factor A0.993
Pax3paired box gene 30.993
Pax6paired box gene 60.993
Nr3c1nuclear receptor subfamily 3, group C, member 10.992
Fgfr3fibroblast growth factor receptor 30.992
Gata4GATA binding protein 40.991
Tbx3T-box 30.990
Notch2Notch gene homolog 2 (Drosophila)0.990
Ctnnb1catenin (cadherin associated protein), beta 10.990
Itgb1integrin beta 1 (fibronectin receptor beta)0.989
Meox2mesenchyme homeobox 20.989
Foxn1forkhead box N10.989
Hoxd13homeobox D130.988
Bmp4bone morphogenetic protein 40.987
Emx1empty spiracles homolog 1 (Drosophila)0.986
Eya1eyes absent 1 homolog (Drosophila)0.986
Ptpn11protein tyrosine phosphatase, non-receptor type 110.986
Chd7chromodomain helicase DNA binding protein 70.983
Foxc1forkhead box C10.981
Cdkn1bcyclin-dependent kinase inhibitor 1B0.980
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.978
Onecut1one cut domain, family member 10.978
Thrbthyroid hormone receptor beta0.978
Fgf8fibroblast growth factor 80.977
Tnftumor necrosis factor0.976
Kiss1KiSS-1 metastasis-suppressor0.973
Emx2empty spiracles homolog 2 (Drosophila)0.969
Fgf10fibroblast growth factor 100.969
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.968
Hoxd11homeobox D110.967
Lmx1aLIM homeobox transcription factor 1 alpha0.966
Hoxa13homeobox A130.966
Ikzf1IKAROS family zinc finger 10.964
Fgf3fibroblast growth factor 30.961
Foxa2forkhead box A20.960
Nr2f2nuclear receptor subfamily 2, group F, member 20.960
Lamc1laminin, gamma 10.960
Apcadenomatosis polyposis coli0.959
Itga3integrin alpha 30.959
Smad4MAD homolog 4 (Drosophila)0.959
Jak2Janus kinase 20.957
Dlx5distal-less homeobox 50.956
En1engrailed 10.955
Pthlhparathyroid hormone-like peptide0.953
Tcfap2atranscription factor AP-2, alpha0.953
Socs1suppressor of cytokine signaling 10.947
Jag1jagged 10.945
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.942
Fshrfollicle stimulating hormone receptor0.941
Ptch1patched homolog 10.941
Tlx3T-cell leukemia, homeobox 30.939
Rb1retinoblastoma 10.939
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.939
Sox7SRY-box containing gene 70.937
Bcl2B-cell leukemia/lymphoma 20.936
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.935
Pax1paired box gene 10.933
Tbx1T-box 10.933
Sall4sal-like 4 (Drosophila)0.930
Pbx1pre B-cell leukemia transcription factor 10.929
Lrp1low density lipoprotein receptor-related protein 10.928
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.927
Tgfb1transforming growth factor, beta 10.926
Rarbretinoic acid receptor, beta0.924
Lef1lymphoid enhancer binding factor 10.923
Sox3SRY-box containing gene 30.920
Tnfsf11tumor necrosis factor (ligand) superfamily, member 110.916
Hoxa1homeobox A10.915
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.912
AxlAXL receptor tyrosine kinase0.909
Myod1myogenic differentiation 10.908
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism