The network for 'positive regulation of nuclear division' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of nuclear division

Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.

NameDescriptionProbabilityFunc Analog Organism
Rps3ribosomal protein S30.057
Rpl23ribosomal protein L230.048
Rpl27ribosomal protein L270.044
Rpl15ribosomal protein L150.036
FauFinkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed0.028
Rps12ribosomal protein S120.022
Rps26ribosomal protein S260.021
Eef1b2eukaryotic translation elongation factor 1 beta 20.021
Psmb1proteasome (prosome, macropain) subunit, beta type 10.020
Rps5ribosomal protein S50.019
Rps6ribosomal protein S60.018
Rps17ribosomal protein S170.017
Rpl35ribosomal protein L350.016
Rps7ribosomal protein S70.016
Rps11ribosomal protein S110.015
Rps10ribosomal protein S100.015
LOC10036049160S ribosomal protein L13-like0.013
Rps19ribosomal protein S190.013
Rpl31ribosomal protein L310.013
Rps21ribosomal protein S210.013
Rps15ribosomal protein S150.013
Ostcoligosaccharyltransferase complex subunit0.013
Rpl26ribosomal protein L260.013
Rps15aribosomal protein S15a0.013
Rpl3ribosomal protein L30.013
Rpsaribosomal protein SA0.013
Rps3aribosomal protein S3a0.012
LOC100188932dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 40.012
Rpl17ribosomal protein L170.012
Rps14ribosomal protein S140.012
Btf3basic transcription factor 30.012
Tceb1transcription elongation factor B (SIII), polypeptide 10.012
Rps2ribosomal protein S20.012
Rpl18ribosomal protein L180.011
Rpl27aribosomal protein L27a0.011
Rpl36aribosomal protein L36a0.011
Rpl36alribosomal protein L36a-like0.011
Rpl18aribosomal protein L18A0.011
Rps27aribosomal protein S27a0.011
LOC100362751ribosomal protein P2-like0.011
Psma2proteasome (prosome, macropain) subunit, alpha type 20.011
Rpl29ribosomal protein L290.011
Rps9ribosomal protein S90.011
Uba52ubiquitin A-52 residue ribosomal protein fusion product 10.010
Rpl19ribosomal protein L190.010
Rps4xribosomal protein S4, X-linked0.010
LOC499782similar to 60S ribosomal protein L120.010
Atp5eATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit0.010
Rpl37ribosomal protein L370.010
LOC301124hypothetical LOC3011240.010
Rps20ribosomal protein S200.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
CG15019CG15019 gene product from transcript CG15019-RB0.015
l(2)03709lethal (2) 037090.013
CG6459CG6459 gene product from transcript CG6459-RA0.012
mRpL49mitochondrial ribosomal protein L490.012
Rpb10CG13628 gene product from transcript CG13628-RA0.011
Trx-2thioredoxin-20.011
CG3887CG3887 gene product from transcript CG3887-RA0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.817
CDC27cell division cycle 27 homolog (S. cerevisiae)0.722
IL1R1interleukin 1 receptor, type I0.398
CDK2cyclin-dependent kinase 20.393
EGFRepidermal growth factor receptor0.368
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.325
ANAPC4anaphase promoting complex subunit 40.305
GRB10growth factor receptor-bound protein 100.270
CCNA2cyclin A20.250
CD80CD80 molecule0.247
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.246
CAV1caveolin 1, caveolae protein, 22kDa0.216
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.168
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.148
AURKBaurora kinase B0.144
SMC6structural maintenance of chromosomes 60.118
CCNB1cyclin B10.111
PTPN1protein tyrosine phosphatase, non-receptor type 10.087
APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)0.082
IGF1Rinsulin-like growth factor 1 receptor0.082
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.080
IRS1insulin receptor substrate 10.078
CDC26cell division cycle 26 homolog (S. cerevisiae)0.073
PLK1polo-like kinase 10.066
JAK2Janus kinase 20.066
CDC20cell division cycle 20 homolog (S. cerevisiae)0.064
RB1retinoblastoma 10.063
RBL2retinoblastoma-like 2 (p130)0.062
ANAPC5anaphase promoting complex subunit 50.062
ANAPC7anaphase promoting complex subunit 70.054
CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1)0.052
CDKN3cyclin-dependent kinase inhibitor 30.051
CAMK2Acalcium/calmodulin-dependent protein kinase II alpha0.051
APPamyloid beta (A4) precursor protein0.050
NRP1neuropilin 10.050
AXIN1axin 10.049
GSK3Bglycogen synthase kinase 3 beta0.048
GHRgrowth hormone receptor0.048
FZR1fizzy/cell division cycle 20 related 1 (Drosophila)0.047
PTTG1pituitary tumor-transforming 10.047
MKNK1MAP kinase interacting serine/threonine kinase 10.046
GAB1GRB2-associated binding protein 10.042
DAZ1deleted in azoospermia 10.039
INSRinsulin receptor0.039
RBL1retinoblastoma-like 1 (p107)0.037
CCNB2cyclin B20.033
SIRT2sirtuin 20.032
ITGB1BP3integrin beta 1 binding protein 30.031
PRRC2Cproline-rich coiled-coil 2C0.028
MIS18BP1MIS18 binding protein 10.028
PGFplacental growth factor0.027
GRAP2GRB2-related adaptor protein 20.027
ANAPC1anaphase promoting complex subunit 10.027
ANAPC11anaphase promoting complex subunit 110.026
CDC14BCDC14 cell division cycle 14 homolog B (S. cerevisiae)0.026
HDAC6histone deacetylase 60.025
MAD2L2MAD2 mitotic arrest deficient-like 2 (yeast)0.025
PDGFAplatelet-derived growth factor alpha polypeptide0.025
CKS2CDC28 protein kinase regulatory subunit 20.024
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.024
IER3immediate early response 30.024
ENGendoglin0.024
CDCA8cell division cycle associated 80.023
TERF2IPtelomeric repeat binding factor 2, interacting protein0.022
CENPFcentromere protein F, 350/400kDa (mitosin)0.022
NTRK3neurotrophic tyrosine kinase, receptor, type 30.022
TTKTTK protein kinase0.021
CLSPNclaspin0.021
MBNL1muscleblind-like (Drosophila)0.021
VEGFAvascular endothelial growth factor A0.021
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.020
THBS1thrombospondin 10.020
RBBP8retinoblastoma binding protein 80.020
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)0.019
PLCG1phospholipase C, gamma 10.019
GAS2L3growth arrest-specific 2 like 30.019
BCAR1breast cancer anti-estrogen resistance 10.018
MAD2L1MAD2 mitotic arrest deficient-like 1 (yeast)0.018
NSMCE1non-SMC element 1 homolog (S. cerevisiae)0.018
UBR3ubiquitin protein ligase E3 component n-recognin 3 (putative)0.018
TINF2TERF1 (TRF1)-interacting nuclear factor 20.017
HGFhepatocyte growth factor (hepapoietin A; scatter factor)0.017
NR4A1nuclear receptor subfamily 4, group A, member 10.017
ORC1origin recognition complex, subunit 10.017
CKS1BCDC28 protein kinase regulatory subunit 1B0.017
PTBP2polypyrimidine tract binding protein 20.017
CCNE1cyclin E10.017
TGFB3transforming growth factor, beta 30.017
PRC1protein regulator of cytokinesis 10.017
STAT5Bsignal transducer and activator of transcription 5B0.017
CAPRIN2caprin family member 20.016
PTPRZ1protein tyrosine phosphatase, receptor-type, Z polypeptide 10.016
KIF20Akinesin family member 20A0.016
PRKCAprotein kinase C, alpha0.016
ASPMasp (abnormal spindle) homolog, microcephaly associated (Drosophila)0.016
CDK1cyclin-dependent kinase 10.016
TNRC6Ctrinucleotide repeat containing 6C0.016
TOP3Atopoisomerase (DNA) III alpha0.016
SMC3structural maintenance of chromosomes 30.015
ADRBK1adrenergic, beta, receptor kinase 10.015
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog0.874
Nos3nitric oxide synthase 3, endothelial cell0.420
Ascl1achaete-scute complex homolog 1 (Drosophila)0.384
Grb10growth factor receptor bound protein 100.380
Lrp6low density lipoprotein receptor-related protein 60.333
Tgfb2transforming growth factor, beta 20.299
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.296
Vegfavascular endothelial growth factor A0.290
Dkk1dickkopf homolog 1 (Xenopus laevis)0.282
Hoxa13homeobox A130.275
Pax8paired box gene 80.272
Ccnb2cyclin B20.246
Ror2receptor tyrosine kinase-like orphan receptor 20.239
Pax3paired box gene 30.216
Hand1heart and neural crest derivatives expressed transcript 10.205
Lhx1LIM homeobox protein 10.203
Otx2orthodenticle homolog 2 (Drosophila)0.202
Plcg1phospholipase C, gamma 10.193
Foxc2forkhead box C20.185
Ccnb1cyclin B10.182
Hoxd13homeobox D130.168
Prrx2paired related homeobox 20.165
Myf5myogenic factor 50.161
Csf1colony stimulating factor 1 (macrophage)0.160
Wnt3awingless-related MMTV integration site 3A0.152
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)0.151
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.148
Onecut1one cut domain, family member 10.145
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.144
Tbrachyury0.143
Fgf8fibroblast growth factor 80.129
Neurog3neurogenin 30.127
En1engrailed 10.126
Ctnnb1catenin (cadherin associated protein), beta 10.126
Cenpfcentromere protein F0.123
Msx1homeobox, msh-like 10.119
Col1a1collagen, type I, alpha 10.119
Notch2Notch gene homolog 2 (Drosophila)0.116
Pax9paired box gene 90.114
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.110
Apcadenomatosis polyposis coli0.108
Runx2runt related transcription factor 20.108
Ccna2cyclin A20.108
CblCasitas B-lineage lymphoma0.103
Axin1axin 10.102
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.099
Gab1growth factor receptor bound protein 2-associated protein 10.098
Bmp7bone morphogenetic protein 70.096
MecomMDS1 and EVI1 complex locus0.094
Cdca8cell division cycle associated 80.090
Alx4aristaless-like homeobox 40.090
Amhr2anti-Mullerian hormone type 2 receptor0.089
Wnt6wingless-related MMTV integration site 60.087
Atoh1atonal homolog 1 (Drosophila)0.082
Prkccprotein kinase C, gamma0.081
Actn2actinin alpha 20.076
Csf3colony stimulating factor 3 (granulocyte)0.076
Hand2heart and neural crest derivatives expressed transcript 20.074
Foxc1forkhead box C10.074
Tbx3T-box 30.072
Meox2mesenchyme homeobox 20.072
Pax6paired box gene 60.071
Jag2jagged 20.071
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.068
Rargretinoic acid receptor, gamma0.067
TyrobpTYRO protein tyrosine kinase binding protein0.065
Gsk3bglycogen synthase kinase 3 beta0.064
Sox17SRY-box containing gene 170.061
Spag5sperm associated antigen 50.061
Tcf3transcription factor 30.061
MdfiMyoD family inhibitor0.060
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.060
Nhlh1nescient helix loop helix 10.060
Cdkn2acyclin-dependent kinase inhibitor 2A0.059
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.059
Six3sine oculis-related homeobox 3 homolog (Drosophila)0.059
Prrx1paired related homeobox 10.058
Lyz2lysozyme 20.057
Kif22kinesin family member 220.057
Eya4eyes absent 4 homolog (Drosophila)0.057
Acanaggrecan0.057
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.055
Prc1protein regulator of cytokinesis 10.054
Foxf1aforkhead box F1a0.054
Cdc25ccell division cycle 25 homolog C (S. pombe)0.054
Sox18SRY-box containing gene 180.054
Sim2single-minded homolog 2 (Drosophila)0.053
Smosmoothened homolog (Drosophila)0.052
Trp53transformation related protein 530.052
Mad2l1MAD2 mitotic arrest deficient-like 1 (yeast)0.051
Kitlkit ligand0.051
Emx1empty spiracles homolog 1 (Drosophila)0.050
D2Ertd750eDNA segment, Chr 2, ERATO Doi 750, expressed0.050
Pcdh12protocadherin 120.049
Birc5baculoviral IAP repeat-containing 50.049
Pou3f1POU domain, class 3, transcription factor 10.049
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.048
Mki67antigen identified by monoclonal antibody Ki 670.048
Jak2Janus kinase 20.048
Cdh5cadherin 50.048
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
CDC27Cdc27p0.020
APC2Apc2p0.017
CDC6Cdc6p0.017
CDC23Cdc23p0.017
SLK19Slk19p0.016
CDC26Cdc26p0.014
RAD53Rad53p0.013
CDC16Cdc16p0.012
CDC20Cdc20p0.011
NSE4Nse4p0.011
CLB4Clb4p0.010