The network for 'dopamine secretion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

dopamine secretion

The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone.

NameDescriptionProbabilityFunc Analog Organism
Chrnecholinergic receptor, nicotinic, epsilon0.210
Chrna7cholinergic receptor, nicotinic, alpha 70.191
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.176
Chrna1cholinergic receptor, nicotinic, alpha 1 (muscle)0.172
FevFEV (ETS oncogene family)0.168
Kcnj4potassium inwardly-rectifying channel, subfamily J, member 40.135
Chrnb1cholinergic receptor, nicotinic, beta 1 (muscle)0.112
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.099
Smad3SMAD family member 30.088
Avpr1barginine vasopressin receptor 1B0.085
Atp2b4ATPase, Ca++ transporting, plasma membrane 40.083
Oprd1opioid receptor, delta 10.073
Chrna6cholinergic receptor, nicotinic, alpha 60.073
Ctrcchymotrypsin C (caldecrin)0.064
Gpr12G protein-coupled receptor 120.060
Il13interleukin 130.059
Gcm1glial cells missing homolog 1 (Drosophila)0.055
Grik3glutamate receptor, ionotropic, kainate 30.054
Scn4asodium channel, voltage-gated, type IV, alpha subunit0.054
Rin1Ras and Rab interactor 10.053
Il2rainterleukin 2 receptor, alpha0.052
Gng7guanine nucleotide binding protein (G protein), gamma 70.052
Magmyelin-associated glycoprotein0.050
Toretrispanning orphan0.049
Olr1361olfactory receptor 13610.049
Olr416olfactory receptor 4160.048
Fgf14fibroblast growth factor 140.048
Cldn16claudin 160.047
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.047
Csf3colony stimulating factor 3 (granulocyte)0.045
LOC60591calcium-activated potassium channel beta subunit0.044
Olr226olfactory receptor 2260.042
RT1-DOaRT1 class II, locus DOa0.037
Dlg4discs, large homolog 4 (Drosophila)0.037
Svs3aseminal vesicle secretory protein 3A0.035
Ppp2r2cprotein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform0.035
Olr287olfactory receptor 2870.035
Atp7bATPase, Cu++ transporting, beta polypeptide0.034
Olr1078olfactory receptor 10780.033
Syn2synapsin II0.033
Gpr83G protein-coupled receptor 830.032
Cacnb1calcium channel, voltage-dependent, beta 1 subunit0.031
Cmtm2aCKLF-like MARVEL transmembrane domain containing 2A0.030
Kcnab2potassium voltage-gated channel, shaker-related subfamily, beta member 20.029
Mchr1melanin-concentrating hormone receptor 10.028
Gucy2dguanylate cyclase 2d0.028
Arpp21cAMP-regulated phosphoprotein 210.026
Foxe3forkhead box E30.026
Myh3myosin, heavy chain 3, skeletal muscle, embryonic0.025
Ptafrplatelet-activating factor receptor0.025
Edn2endothelin 20.024
Gabrr1gamma-aminobutyric acid (GABA) receptor, rho 10.024
Akp3alkaline phosphatase 3, intestine, not Mn requiring0.024
Pthparathyroid hormone0.024
Cntn2contactin 2 (axonal)0.023
Olr1641olfactory receptor 16410.023
Syn1synapsin I0.023
Arandrogen receptor0.023
Slc16a8solute carrier family 16, member 8 (monocarboxylic acid transporter 3)0.022
Rgs14regulator of G-protein signaling 140.022
Atxn1ataxin 10.022
Myt1lmyelin transcription factor 1-like0.022
Cyfip2cytoplasmic FMR1 interacting protein 20.022
Cd79bCd79b molecule, immunoglobulin-associated beta0.022
Htr1d5-hydroxytryptamine (serotonin) receptor 1D0.022
Vom2r53vomeronasal 2 receptor, 530.021
Kcnmb1potassium large conductance calcium-activated channel, subfamily M, beta member 10.021
Aqp2aquaporin 2 (collecting duct)0.021
Gria2glutamate receptor, ionotropic, AMPA 20.021
Gjb5gap junction protein, beta 50.021
Prm2protamine 20.021
Slc8a2solute carrier family 8 (sodium/calcium exchanger), member 20.020
Crxcone-rod homeobox0.020
Hrh2histamine receptor H 20.020
Olr1082olfactory receptor 10820.020
Oprk1opioid receptor, kappa 10.020
Aif1lallograft inflammatory factor 1-like0.020
Clcn1chloride channel 10.020
RGD1564664similar to LOC387763 protein0.020
Hrh4histamine receptor H40.020
Pparaperoxisome proliferator activated receptor alpha0.020
Gabregamma-aminobutyric acid (GABA) A receptor, epsilon0.019
Rgs8regulator of G-protein signaling 80.019
Rab15RAB15, member RAS oncogene family0.019
Muc3amucin 3A, cell surface associated0.019
Strnstriatin, calmodulin binding protein0.019
Cd46CD46 molecule, complement regulatory protein0.019
Prrxl1paired related homeobox protein-like 10.018
Svs1seminal vesicle secretory protein 10.018
Grm4glutamate receptor, metabotropic 40.018
Cyp4f4cytochrome P450, family 4, subfamily f, polypeptide 40.018
Map2k1mitogen activated protein kinase kinase 10.018
Fat3FAT tumor suppressor homolog 3 (Drosophila)0.018
Psg19pregnancy specific glycoprotein 190.018
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 31.000
Chrnb2cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)0.998
Chrnb4cholinergic receptor, nicotinic, beta polypeptide 40.994
Chrna3cholinergic receptor, nicotinic, alpha polypeptide 30.962
Drd2dopamine receptor D20.853
Nos1nitric oxide synthase 1, neuronal0.530
Pitx3paired-like homeodomain transcription factor 30.338
Slc18a2solute carrier family 18 (vesicular monoamine), member 20.276
Cacna1bcalcium channel, voltage-dependent, N type, alpha 1B subunit0.241
Lhx3LIM homeobox protein 30.231
Oprm1opioid receptor, mu 10.213
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.212
Gabbr2gamma-aminobutyric acid (GABA) B receptor, 20.193
Cplx1complexin 10.137
Chrna10cholinergic receptor, nicotinic, alpha polypeptide 100.126
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.125
Grm2glutamate receptor, metabotropic 20.113
Lpar5lysophosphatidic acid receptor 50.097
Kcns2K+ voltage-gated channel, subfamily S, 20.093
Hcn3hyperpolarization-activated, cyclic nucleotide-gated K+ 30.081
Emx1empty spiracles homolog 1 (Drosophila)0.074
Stk32bserine/threonine kinase 32B0.073
Thrbthyroid hormone receptor beta0.068
Oprl1opioid receptor-like 10.068
Rit2Ras-like without CAAX 20.066
Htr5a5-hydroxytryptamine (serotonin) receptor 5A0.066
Drd1adopamine receptor D1A0.063
Sult4a1sulfotransferase family 4A, member 10.063
Chrna7cholinergic receptor, nicotinic, alpha polypeptide 70.060
C1ql1complement component 1, q subcomponent-like 10.058
Gjd2gap junction protein, delta 20.056
Fshrfollicle stimulating hormone receptor0.056
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.053
Mab21l2mab-21-like 2 (C. elegans)0.053
Neurod2neurogenic differentiation 20.052
Pcsk1nproprotein convertase subtilisin/kexin type 1 inhibitor0.052
Cnr1cannabinoid receptor 1 (brain)0.051
Alkanaplastic lymphoma kinase0.050
Rgs8regulator of G-protein signaling 80.048
Syt1synaptotagmin I0.048
Syt13synaptotagmin XIII0.046
Esrrbestrogen related receptor, beta0.045
Nell2NEL-like 2 (chicken)0.043
Chrna6cholinergic receptor, nicotinic, alpha polypeptide 60.043
Ebf3early B-cell factor 30.041
Pde1bphosphodiesterase 1B, Ca2+-calmodulin dependent0.040
Kcnq2potassium voltage-gated channel, subfamily Q, member 20.040
Pde6bphosphodiesterase 6B, cGMP, rod receptor, beta polypeptide0.040
Rs1retinoschisis (X-linked, juvenile) 1 (human)0.040
Ank1ankyrin 1, erythroid0.038
Kcne1lpotassium voltage-gated channel, Isk-related family, member 1-like, pseudogene0.037
Htr1d5-hydroxytryptamine (serotonin) receptor 1D0.037
Slc6a5solute carrier family 6 (neurotransmitter transporter, glycine), member 50.036
Opn1swopsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)0.034
Rapsnreceptor-associated protein of the synapse0.031
Olfr140olfactory receptor 1400.029
Cgaglycoprotein hormones, alpha subunit0.028
Adora2aadenosine A2a receptor0.027
Lcn8lipocalin 80.027
Scgnsecretagogin, EF-hand calcium binding protein0.026
Mybphmyosin binding protein H0.026
Cox8ccytochrome c oxidase, subunit VIIIc0.026
Slc30a3solute carrier family 30 (zinc transporter), member 30.026
Cntn2contactin 20.025
Gnb3guanine nucleotide binding protein (G protein), beta 30.025
Krt12keratin 120.024
Apc2adenomatosis polyposis coli 20.023
Opn1mwopsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)0.023
Tff1trefoil factor 10.023
Ywhahtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.023
Cacna1dcalcium channel, voltage-dependent, L type, alpha 1D subunit0.023
Fgf3fibroblast growth factor 30.023
Myod1myogenic differentiation 10.022
Vsx2visual system homeobox 20.022
Sncasynuclein, alpha0.022
Chrna9cholinergic receptor, nicotinic, alpha polypeptide 90.022
Cdk5r2cyclin-dependent kinase 5, regulatory subunit 2 (p39)0.022
Calb2calbindin 20.022
Sstr1somatostatin receptor 10.020
Gnrh1gonadotropin releasing hormone 10.020
Thtyrosine hydroxylase0.020
Glra1glycine receptor, alpha 1 subunit0.020
Atp7bATPase, Cu++ transporting, beta polypeptide0.019
Slc18a3solute carrier family 18 (vesicular monoamine), member 30.018
Nhlh1nescient helix loop helix 10.018
Naa11N(alpha)-acetyltransferase 11, NatA catalytic subunit0.018
Ptprnprotein tyrosine phosphatase, receptor type, N0.018
Psapl1prosaposin-like 10.018
Gnao1guanine nucleotide binding protein, alpha O0.018
Smyd1SET and MYND domain containing 10.017
Gng3guanine nucleotide binding protein (G protein), gamma 30.017
Muskmuscle, skeletal, receptor tyrosine kinase0.017
Znrf4zinc and ring finger 40.017
Accn4amiloride-sensitive cation channel 4, pituitary0.017
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism