The network for 'intermediate filament based process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

intermediate filament based process

Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins.

NameDescriptionProbabilityFunc Analog Organism
Neflneurofilament, light polypeptide0.645
Nefmneurofilament, medium polypeptide0.525
Anxa2annexin A20.092
Nefhneurofilament, heavy polypeptide0.088
Anxa5annexin A50.045
Actc1actin, alpha, cardiac muscle 10.032
Inainternexin neuronal intermediate filament protein, alpha0.029
Mgpmatrix Gla protein0.028
Col5a2collagen, type V, alpha 20.027
Hspb1heat shock protein 10.025
Cplx1complexin 10.024
Cox6ccytochrome c oxidase, subunit VIc0.024
Dync1i1dynein cytoplasmic 1 intermediate chain 10.022
Slc16a3solute carrier family 16, member 3 (monocarboxylic acid transporter 4)0.022
Spock2sparc/osteonectin, cwcv and kazal-like domains proteoglycan 20.022
Fn1fibronectin 10.021
RGD1563319similar to RIKEN cDNA 6330512M04 gene0.020
Fgf9fibroblast growth factor 90.020
CadpsCa++-dependent secretion activator0.020
Capgcapping protein (actin filament), gelsolin-like0.018
Sparcsecreted protein, acidic, cysteine-rich (osteonectin)0.017
Kcna1potassium voltage-gated channel, shaker-related subfamily, member 10.016
Ifitm3interferon induced transmembrane protein 30.016
Loxlysyl oxidase0.016
Uchl1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)0.016
Crabp1cellular retinoic acid binding protein 10.016
Kif5ckinesin family member 5C0.015
RGD1309906similar to RIKEN cDNA 2310004I24 gene0.015
Chgbchromogranin B0.015
Cryabcrystallin, alpha B0.015
VgfVGF nerve growth factor inducible0.015
Flncfilamin C, gamma0.013
Sox10SRY (sex determining region Y)-box 100.013
Klk6kallikrein related-peptidase 60.013
Csrp3cysteine and glycine-rich protein 30.012
Taglntransgelin0.012
Kcnmb4potassium large conductance calcium-activated channel, subfamily M, beta member 40.012
Galgalanin prepropeptide0.011
Elavl2ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)0.011
Calcbcalcitonin-related polypeptide, beta0.011
Sigmar1sigma non-opioid intracellular receptor 10.011
Snap91synaptosomal-associated protein 910.011
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.011
S1pr2sphingosine-1-phosphate receptor 20.011
Capn2calpain 20.011
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.011
Ckmcreatine kinase, muscle0.011
Ctgfconnective tissue growth factor0.011
Prphperipherin0.011
Ascl2achaete-scute complex homolog 2 (Drosophila)0.011
P2ry2purinergic receptor P2Y, G-protein coupled, 20.010
Scn3bsodium channel, voltage-gated, type III, beta0.010
Campcathelicidin antimicrobial peptide0.010
Dynlrb1dynein light chain roadblock-type 10.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
CELE_ZK1025.3Protein ZK1025.30.011
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
BEAF-32Boundary element-associated factor of 32kD0.335
SetCG4299 gene product from transcript CG4299-RA0.103
Aos1CG12276 gene product from transcript CG12276-RA0.095
phlpole hole0.077
CG9797CG9797 gene product from transcript CG9797-RA0.038
Rpb11CG6840 gene product from transcript CG6840-RA0.038
RPA2Replication protein A20.038
U2af50U2 small nuclear riboprotein auxiliary factor 500.037
CG6961CG6961 gene product from transcript CG6961-RA0.031
bafbarrier to autointegration factor0.030
Nup62Nucleoporin 620.025
Nup50Nucleoporin 500.024
U2af38U2 small nuclear riboprotein auxiliary factor 380.023
CG8289CG8289 gene product from transcript CG8289-RA0.023
SsrpStructure specific recognition protein0.021
RnpS1RNA-binding protein S10.021
Arp14DActin-related protein 14D0.021
nop5CG10206 gene product from transcript CG10206-RA0.021
mormoira0.020
MED22Mediator complex subunit 220.019
CG12155CG12155 gene product from transcript CG12155-RA0.019
CG14464CG14464 gene product from transcript CG14464-RC0.018
l(2)03709lethal (2) 037090.017
Su(var)205Suppressor of variegation 2050.016
CG2982CG2982 gene product from transcript CG2982-RB0.016
CG3887CG3887 gene product from transcript CG3887-RA0.016
Tif-IACG3278 gene product from transcript CG3278-RA0.016
T-cp1Tcp1-like0.015
CG11076CG11076 gene product from transcript CG11076-RB0.015
E2f2E2F transcription factor 20.015
AP-1sigmaCG5864 gene product from transcript CG5864-RA0.015
RipalphaRPA-interacting protein alpha0.014
Top2Topoisomerase 20.014
CG17202CG17202 gene product from transcript CG17202-RA0.014
CG6610CG6610 gene product from transcript CG6610-RA0.014
G-ialpha65AG protein alphai subunit 65A0.014
CG2691CG2691 gene product from transcript CG2691-RA0.013
CG7006CG7006 gene product from transcript CG7006-RA0.013
CG5525CG5525 gene product from transcript CG5525-RA0.013
Rpb5CG11979 gene product from transcript CG11979-RA0.013
Arc-p34CG10954 gene product from transcript CG10954-RA0.013
eIF4AIIICG7483 gene product from transcript CG7483-RA0.013
vig2CG11844 gene product from transcript CG11844-RB0.012
Art1Arginine methyltransferase 10.012
Prp8pre-mRNA processing factor 80.012
CG10286CG10286 gene product from transcript CG10286-RA0.012
CG14220CG14220 gene product from transcript CG14220-RA0.012
Nedd8CG10679 gene product from transcript CG10679-RA0.011
Su(var)3-9Suppressor of variegation 3-90.011
CG1542CG1542 gene product from transcript CG1542-RA0.011
CG11583CG11583 gene product from transcript CG11583-RA0.011
PdswCG8844 gene product from transcript CG8844-RA0.011
modmodulo0.011
Ranbp9CG5252 gene product from transcript CG5252-RA0.011
ATPsyn-gammaATP synthase-gamma chain0.011
CG3436CG3436 gene product from transcript CG3436-RA0.011
CG5220CG5220 gene product from transcript CG5220-RA0.010
eIF2B-gammaCG8190 gene product from transcript CG8190-RA0.010
CrkCG1587 gene product from transcript CG1587-RC0.010
LaLa autoantigen-like0.010
Rrp1Recombination repair protein 10.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
KRT15keratin 151.000
KRT6Bkeratin 6B1.000
KRT19keratin 190.999
ERBB2IPerbb2 interacting protein0.997
KRT6Akeratin 6A0.986
KRT18keratin 180.985
KRT8keratin 80.984
KRT14keratin 140.973
PKP1plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)0.958
KRT17keratin 170.928
KRT5keratin 50.903
PSEN1presenilin 10.844
SMAD9SMAD family member 90.839
JUPjunction plakoglobin0.821
MTMR12myotubularin related protein 120.804
KRT34keratin 340.783
APCadenomatous polyposis coli0.756
PPP2R2Bprotein phosphatase 2, regulatory subunit B, beta0.711
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.696
UBQLN1ubiquilin 10.680
KRT33Bkeratin 33B0.672
EPS15epidermal growth factor receptor pathway substrate 150.670
KRT81keratin 810.627
TP63tumor protein p630.623
MTM1myotubularin 10.606
CCDC85Bcoiled-coil domain containing 85B0.500
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)0.494
DTNAdystrobrevin, alpha0.482
TRIM29tripartite motif containing 290.428
KRT16keratin 160.407
SPRR1Asmall proline-rich protein 1A0.405
PKP2plakophilin 20.345
KRT32keratin 320.337
ITGB4integrin, beta 40.331
EXOC8exocyst complex component 80.326
ALBalbumin0.288
DSPdesmoplakin0.281
KRT1keratin 10.273
TEKT4tektin 40.241
DMDdystrophin0.226
KRT36keratin 360.193
KIAA0408KIAA04080.193
KRT4keratin 40.180
MARK3MAP/microtubule affinity-regulating kinase 30.169
KRT6Ckeratin 6C0.166
MTMR9myotubularin related protein 90.163
TJP1tight junction protein 1 (zona occludens 1)0.157
COL17A1collagen, type XVII, alpha 10.154
DSG3desmoglein 30.143
KRT75keratin 750.141
KRT31keratin 310.141
TOR1Atorsin family 1, member A (torsin A)0.138
STON2stonin 20.133
KRT33Akeratin 33A0.121
KRT13keratin 130.100
KRT2keratin 20.093
KRT9keratin 90.089
KRT37keratin 370.089
IVLinvolucrin0.083
KRT38keratin 380.075
PKP4plakophilin 40.075
KRT35keratin 350.073
GJB5gap junction protein, beta 5, 31.1kDa0.071
KLK10kallikrein-related peptidase 100.071
SPRR1Bsmall proline-rich protein 1B0.070
EXOC1exocyst complex component 10.069
RAD23BRAD23 homolog B (S. cerevisiae)0.064
BAIAP2BAI1-associated protein 20.061
RHODras homolog gene family, member D0.055
SPRR3small proline-rich protein 30.052
FRMD5FERM domain containing 50.052
SLURP1secreted LY6/PLAUR domain containing 10.052
PHLPP1PH domain and leucine rich repeat protein phosphatase 10.048
PTPRJprotein tyrosine phosphatase, receptor type, J0.047
SPTBN1spectrin, beta, non-erythrocytic 10.044
GJB3gap junction protein, beta 3, 31kDa0.042
TJP2tight junction protein 2 (zona occludens 2)0.041
ELF3E74-like factor 3 (ets domain transcription factor, epithelial-specific )0.041
KIAA1217KIAA12170.039
SMAD4SMAD family member 40.038
KIF5Bkinesin family member 5B0.038
TOR1Btorsin family 1, member B (torsin B)0.038
DSC3desmocollin 30.037
DSC2desmocollin 20.036
SOS1son of sevenless homolog 1 (Drosophila)0.036
MTMR6myotubularin related protein 60.036
PPLperiplakin0.035
DSG1desmoglein 10.034
LY6G6Clymphocyte antigen 6 complex, locus G6C0.034
KRT85keratin 850.034
TCHPtrichoplein, keratin filament binding0.033
ATF7IPactivating transcription factor 7 interacting protein0.033
VIMvimentin0.032
S100A14S100 calcium binding protein A140.031
BAG1BCL2-associated athanogene0.031
PAX9paired box 90.030
LORloricrin0.029
RHPN1rhophilin, Rho GTPase binding protein 10.029
LY6Dlymphocyte antigen 6 complex, locus D0.028
CASKcalcium/calmodulin-dependent serine protein kinase (MAGUK family)0.028
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Krt17keratin 170.962
Krt5keratin 50.952
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.947
Krt6akeratin 6A0.934
Pafah1b1platelet-activating factor acetylhydrolase, isoform 1b, subunit 10.914
Krt19keratin 190.909
Sprr1asmall proline-rich protein 1A0.894
Krt14keratin 140.891
Krtap8-1keratin associated protein 8-10.840
Krt13keratin 130.811
Pkp1plakophilin 10.777
Nphp4nephronophthisis 4 (juvenile) homolog (human)0.768
Krt1keratin 10.748
Krt71keratin 710.736
Pplperiplakin0.706
Tgm3transglutaminase 3, E polypeptide0.685
Psapl1prosaposin-like 10.657
Krt33bkeratin 33B0.578
Krt35keratin 350.578
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.574
Lgals7lectin, galactose binding, soluble 70.517
Il1f5interleukin 1 family, member 5 (delta)0.489
Krt72-pskeratin 72, pseudogene0.472
Krt7keratin 70.467
Serpinb5serine (or cysteine) peptidase inhibitor, clade B, member 50.447
Cdsncorneodesmosin0.423
Wnt10awingless related MMTV integration site 10a0.422
Capn8calpain 80.416
Krt33akeratin 33A0.404
Smad4MAD homolog 4 (Drosophila)0.343
Krt36keratin 360.340
Fgfr2fibroblast growth factor receptor 20.335
Dlx3distal-less homeobox 30.328
Krt8keratin 80.325
Syncsyncoilin0.319
Egfrepidermal growth factor receptor0.314
Krt6bkeratin 6B0.314
Krt86keratin 860.298
Krtap6-2keratin associated protein 6-20.297
Krt85keratin 850.288
Pthlhparathyroid hormone-like peptide0.280
5430421N21RikRIKEN cDNA 5430421N21 gene0.255
Nphp1nephronophthisis 1 (juvenile) homolog (human)0.238
Krt84keratin 840.238
Trp63transformation related protein 630.237
Sfnstratifin0.230
Syt8synaptotagmin VIII0.222
Lypd3Ly6/Plaur domain containing 30.218
Desdesmin0.214
Krt27keratin 270.211
Tff1trefoil factor 10.209
Klk6kallikrein related-peptidase 60.208
Nefmneurofilament, medium polypeptide0.205
S100a3S100 calcium binding protein A30.205
S100a14S100 calcium binding protein A140.199
Trim29tripartite motif-containing 290.197
Krtdapkeratinocyte differentiation associated protein0.196
Alox8arachidonate 8-lipoxygenase0.187
Krtap5-1keratin associated protein 5-10.159
Calm4calmodulin 40.155
Krt4keratin 40.149
Pitx1paired-like homeodomain transcription factor 10.146
Foxn1forkhead box N10.145
Krtap3-1keratin associated protein 3-10.139
Ly6g6clymphocyte antigen 6 complex, locus G6C0.139
Krt82keratin 820.130
Sprr3small proline-rich protein 30.130
Crct1cysteine-rich C-terminal 10.128
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.126
Neflneurofilament, light polypeptide0.125
Epha2Eph receptor A20.125
Krt15keratin 150.125
Gfapglial fibrillary acidic protein0.123
Tacstd2tumor-associated calcium signal transducer 20.122
Endouendonuclease, polyU-specific0.121
Krt32keratin 320.113
Pscaprostate stem cell antigen0.110
Slc46a2solute carrier family 46, member 20.110
Rcvrnrecoverin0.103
Padi3peptidyl arginine deiminase, type III0.103
Cyp2b19cytochrome P450, family 2, subfamily b, polypeptide 190.102
Sncbsynuclein, beta0.100
Arhgef2rho/rac guanine nucleotide exchange factor (GEF) 20.100
Slurp1secreted Ly6/Plaur domain containing 10.100
Hrhairless0.100
Klk7kallikrein related-peptidase 7 (chymotryptic, stratum corneum)0.099
Krt16keratin 160.098
Ppt1palmitoyl-protein thioesterase 10.098
Krtap16-8keratin associated protein 16-80.098
Krt78keratin 780.096
Mt4metallothionein 40.093
Tagln3transgelin 30.091
Asprv1aspartic peptidase, retroviral-like 10.089
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.089
Prss22protease, serine, 220.084
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.082
Krtap3-3keratin associated protein 3-30.082
Gpr87G protein-coupled receptor 870.079
Fgf9fibroblast growth factor 90.079
Atp2a1ATPase, Ca++ transporting, cardiac muscle, fast twitch 10.078
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism