The network for 'negative regulation of developmental growth' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of developmental growth

Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth.

NameDescriptionProbabilityFunc Analog Organism
Cav1caveolin 1, caveolae protein0.195
Cd37CD37 molecule0.151
Smad7SMAD family member 70.088
Nek9NIMA (never in mitosis gene a)- related kinase 90.077
LOC100362824caveolin 2-like0.071
Usf2upstream transcription factor 2, c-fos interacting0.058
Cishcytokine inducible SH2-containing protein0.054
Itgamintegrin, alpha M0.048
Tgfbr2transforming growth factor, beta receptor II0.045
Nos3nitric oxide synthase 3, endothelial cell0.043
Inpp5dinositol polyphosphate-5-phosphatase D0.037
Fgfr1Fibroblast growth factor receptor 10.030
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.030
Hk1hexokinase 10.029
A3galt2alpha 1,3-galactosyltransferase 20.028
Pld2phospholipase D20.024
Pkn2protein kinase N20.024
Fgfr2fibroblast growth factor receptor 20.023
Ubtfupstream binding transcription factor, RNA polymerase I0.022
Ptafrplatelet-activating factor receptor0.022
Mpripmyosin phosphatase Rho interacting protein0.021
Olfml2bolfactomedin-like 2B0.021
Sod3superoxide dismutase 3, extracellular0.021
Gna15guanine nucleotide binding protein, alpha 150.020
Mcammelanoma cell adhesion molecule0.020
Adrb2adrenergic, beta-2-, receptor, surface0.020
Cav2caveolin 20.019
Grin2aglutamate receptor, ionotropic, N-methyl D-aspartate 2A0.019
Fmnl1formin-like 10.018
Rab1bRAB1B, member RAS oncogene family0.018
Nedd4neural precursor cell expressed, developmentally down-regulated 40.018
Ptprcprotein tyrosine phosphatase, receptor type, C0.017
Timp3TIMP metallopeptidase inhibitor 30.017
Bcl2B-cell CLL/lymphoma 20.017
Tcof1Treacher Collins-Franceschetti syndrome 1 homolog (human)0.017
RGD1559896similar to RIKEN cDNA 2310022B050.016
Pgrprogesterone receptor0.016
Cpxm2carboxypeptidase X (M14 family), member 20.016
Il2rginterleukin 2 receptor, gamma0.015
Tubtubby homolog (mouse)0.015
Acvr1activin A receptor, type I0.015
Cyfip1cytoplasmic FMR1 interacting protein 10.015
Pld1phospholipase D10.015
Sox2SRY (sex determining region Y)-box 20.014
Sema6bsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B0.014
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.014
Gabbr2gamma-aminobutyric acid (GABA) B receptor 20.014
Nfianuclear factor I/A0.014
Nos1nitric oxide synthase 1, neuronal0.013
Alox5arachidonate 5-lipoxygenase0.013
Fzd2frizzled homolog 2 (Drosophila)0.013
Sept8septin 80.013
Nfibnuclear factor I/B0.013
B4galt1UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 10.013
Gcn1l1GCN1 general control of amino-acid synthesis 1-like 1 (yeast)0.013
Shank1SH3 and multiple ankyrin repeat domains 10.013
Prkcaprotein kinase C, alpha0.013
Cd38CD38 molecule0.013
Irf2interferon regulatory factor 20.013
Ptprsprotein tyrosine phosphatase, receptor type, S0.012
Rararetinoic acid receptor, alpha0.012
Epn2epsin 20.012
Fgf17fibroblast growth factor 170.012
Glg1golgi apparatus protein 10.012
Sirpasignal-regulatory protein alpha0.012
Adrbk1adrenergic, beta, receptor kinase 10.012
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.012
Serpine2serine (or cysteine) peptidase inhibitor, clade E, member 20.012
Prkchprotein kinase C, eta0.012
Gja1gap junction protein, alpha 10.012
Cyp2s1cytochrome P450, family 2, subfamily s, polypeptide 10.011
Camk2acalcium/calmodulin-dependent protein kinase II alpha0.011
Prkcdprotein kinase C, delta0.011
Gna12guanine nucleotide binding protein (G protein) alpha 120.011
Nr2f6nuclear receptor subfamily 2, group F, member 60.011
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.011
Socs3suppressor of cytokine signaling 30.011
Nlgn2neuroligin 20.011
Fnbp1formin binding protein 10.011
Jak1Janus kinase 10.011
Hspb2heat shock protein beta 20.011
Rab27aRAB27A, member RAS oncogene family0.011
Tcf4transcription factor 40.011
Plcg2phospholipase C, gamma 20.011
Ageradvanced glycosylation end product-specific receptor0.011
Vav1vav 1 guanine nucleotide exchange factor0.010
Smurf2SMAD specific E3 ubiquitin protein ligase 20.010
Casp1caspase 10.010
Muskmuscle, skeletal, receptor tyrosine kinase0.010
Rab3il1RAB3A interacting protein (rabin3)-like 10.010
Rock2Rho-associated coiled-coil containing protein kinase 20.010
Prkar2aprotein kinase, cAMP dependent regulatory, type II alpha0.010
Olr857olfactory receptor 8570.010
Cops7aCOP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)0.010
Fam65afamily with sequence similarity 65, member A0.010
Pecam1platelet/endothelial cell adhesion molecule 10.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
cst-1Protein CST-10.022
ttyh-1Protein TTYH-10.021
cst-2Protein CST-20.016
ain-1Protein AIN-10.014
unc-68Protein UNC-680.013
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
efnb2aephrin B2a0.466
lhx2bLIM homeobox 2b0.383
bocbrother of CDO0.312
robo2roundabout homolog 20.258
slit3slit (Drosophila) homolog 30.189
nf1aneurofibromin 1a0.174
foxa1forkhead box A10.129
bmp2bbone morphogenetic protein 2b0.115
fgfr3fibroblast growth factor receptor 30.112
nog1noggin 10.105
ptpraprotein tyrosine phosphatase, receptor type, A0.104
wnt11rwingless-type MMTV integration site family, member 11, related0.103
cdh2cadherin 2, neuronal0.102
fzd7afrizzled homolog 7a0.081
fzd2frizzled homolog 20.080
notch2notch homolog 20.075
col7a1lcollagen type VII alpha 1-like0.074
nrp2bneuropilin 2b0.073
efnb3bephrin B3b0.063
fgfr4fibroblast growth factor receptor 40.063
pea3ETS-domain transcription factor pea30.060
sh3gl1bSH3-domain GRB2-like 1b0.056
nkd1naked cuticle homolog 1 (Drosophila)0.054
ptprsaprotein tyrosine phosphatase, receptor type, s, a0.054
ascl1aachaete-scute complex-like 1a (Drosophila)0.048
rbfox1lRNA binding protein, fox-1 homolog (C. elegans) 1-like0.047
crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.046
cdkn1acyclin-dependent kinase inhibitor 1A0.045
slit2slit (Drosophila) homolog 20.043
adrb2aadrenergic receptor, beta 2a0.043
fstl1bfollistatin-like 1b0.041
ets1av-ets erythroblastosis virus E26 oncogene homolog 1a0.040
sdc2syndecan 20.039
zbtb4zinc finger and BTB domain containing 40.037
bambiaBMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a0.036
fgfrl1afibroblast growth factor receptor-like 1a0.036
ntn2netrin 20.035
msxbmuscle segment homeobox B0.034
igf2binsulin-like growth factor 2b0.034
fmr1fragile X mental retardation 10.033
sulf1sulfatase 10.033
mycbp2MYC binding protein 20.033
llgl2lethal giant larvae homolog 2 (Drosophila)0.033
gli3GLI-Kruppel family member GLI30.031
arnt2aryl hydrocarbon receptor nuclear translocator 20.031
atp6v1baATPase, H+ transporting, lysosomal, V1 subunit B, member a0.030
mapk1mitogen-activated protein kinase 10.028
itgb1b.1integrin, beta 1b.10.028
gap43growth associated protein 430.028
pcdh8protocadherin 80.027
ntn1anetrin 1a0.027
adipoqladiponectin, C1Q and collagen domain containing, like0.027
has2hyaluronan synthase 20.026
ptprkprotein tyrosine phosphatase, receptor type, K0.026
fzd7bfrizzled homolog 7b0.026
sfrp1asecreted frizzled-related protein 1a0.025
ldb2aLIM-domain binding factor 2a0.025
pou1f1POU domain, class 1, transcription factor 10.025
ptk2.1protein tyrosine kinase 2a0.025
notch3notch homolog 30.024
nav3neuron navigator 30.024
sema3fbsemaphorin 3fb0.024
neo1neogenin 10.024
col5a2lcollagen, type V, alpha 2-like0.023
csf3rcolony stimulating factor 3 receptor (granulocyte)0.023
traf4atnf receptor-associated factor 4a0.022
ctsl1bcathepsin L, 1 b0.022
sgk1serum/glucocorticoid regulated kinase 10.022
zdhhc8bzinc finger, DHHC-type containing 8b0.022
sema3dsemaphorin 3d0.020
nrg2aneuregulin 2a0.020
acvr1bactivin A receptor, type IB0.020
nrg1neuregulin 10.020
notum3notum 30.019
sox2SRY-box containing gene 20.019
tbx1T-box 10.019
fgfr1bfibroblast growth factor receptor 1b0.019
olfm2olfactomedin 20.019
tcf7transcription factor 7 (T-cell specific, HMG-box)0.019
grnbgranulin b0.018
gli1GLI-Kruppel family member 10.018
ntrk2aneurotrophic tyrosine kinase, receptor, type 2a0.018
mecomMDS1 and EVI1 complex locus0.018
nrarpanotch-regulated ankyrin repeat protein a0.018
grem2gremlin 2, cysteine knot superfamily0.018
tnctenascin C0.017
ephb4beph receptor B4b0.017
plxnb2aplexin b2a0.017
ebf3early B-cell factor 30.016
chatcholine acetyltransferase0.016
npc1Niemann-Pick disease, type C10.016
kif5bbkinesin family member 5B, b0.016
tnfsf10ltumor necrosis factor (ligand) superfamily, member 10 like0.016
cacnb1calcium channel, voltage-dependent, beta 1 subunit0.016
eomesbeomesodermin homolog b0.016
axin1axin 10.015
ucn3lurocortin 3, like0.015
bmp2abone morphogenetic protein 2a0.015
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Rac1CG2248 gene product from transcript CG2248-RA0.847
Fak56DFocal Adhesion Kinase0.829
Mob2CG11711 gene product from transcript CG11711-RC0.805
jebjelly belly0.794
PtenCG5671 gene product from transcript CG5671-RB0.767
witwishful thinking0.620
neuroliginCG13772 gene product from transcript CG13772-RA0.618
Pi3K92ECG4141 gene product from transcript CG4141-RB0.610
Pk61CProtein kinase 61C0.570
kibrakibra ortholog0.558
Vap-33-1CG5014 gene product from transcript CG5014-RB0.440
MadMothers against dpp0.429
S6kRPS6-p70-protein kinase0.406
CG14869CG14869 gene product from transcript CG14869-RB0.406
wbwing blister0.346
trioCG18214 gene product from transcript CG18214-RA0.338
DadDaughters against dpp0.310
Dap160Dynamin associated protein 1600.288
Wnt5Wnt oncogene analog 50.280
CycDCyclin D0.277
HGTXCG13475 gene product from transcript CG13475-RB0.268
Liprin-alphaCG11199 gene product from transcript CG11199-RB0.262
nwknervous wreck0.253
shotshort stop0.248
CG13253CG13253 gene product from transcript CG13253-RB0.237
drkdownstream of receptor kinase0.218
Tsc1CG6147 gene product from transcript CG6147-RA0.210
CkIIalphaCasein kinase II alpha subunit0.207
AdoRAdenosine receptor0.202
LanALaminin A0.196
mewmultiple edematous wings0.196
S6kIIRPS6-protein kinase-II0.187
unc-104CG8566 gene product from transcript CG8566-RB0.179
unc-5CG8166 gene product from transcript CG8166-RA0.178
Mst57DbMale-specific RNA 57Db0.174
Nf1Neurofibromin 10.172
Zyx102EFCG32018 gene product from transcript CG32018-RA0.171
cicubitus interruptus0.168
TbhTyramine beta hydroxylase0.162
Trim9CG31721 gene product from transcript CG31721-RB0.158
fz2frizzled 20.154
RanBPMRan-binding protein M0.154
Cdk4Cyclin-dependent kinase 40.148
Ten-aTenascin accessory0.147
chicoCG5686 gene product from transcript CG5686-RB0.146
LanB2Laminin B20.146
chbchromosome bows0.145
X11LCG5675 gene product from transcript CG5675-RB0.144
AlkCG8250 gene product from transcript CG8250-RA0.144
Ras85DRas oncogene at 85D0.140
FsnCG4643 gene product from transcript CG4643-RA0.137
Akt1CG4006 gene product from transcript CG4006-RA0.137
stnBstoned B0.134
vavCG7893 gene product from transcript CG7893-RB0.127
RagACG11968 gene product from transcript CG11968-RA0.126
Octbeta2RCG33976 gene product from transcript CG33976-RA0.123
Aplip1APP-like protein interacting protein 10.119
dcodiscs overgrown0.116
stumpsCG31317 gene product from transcript CG31317-RC0.116
Fmr1CG6203 gene product from transcript CG6203-RC0.112
EphrinCG1862 gene product from transcript CG1862-RA0.110
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
FYNFYN oncogene related to SRC, FGR, YES0.898
CREBBPCREB binding protein0.755
ARandrogen receptor0.562
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.362
TSC2tuberous sclerosis 20.353
FGF1fibroblast growth factor 1 (acidic)0.334
SNX9sorting nexin 90.315
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.290
STK3serine/threonine kinase 30.207
WIPF1WAS/WASL interacting protein family, member 10.206
BMPR1Abone morphogenetic protein receptor, type IA0.157
SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)0.118
SMAD1SMAD family member 10.104
ATG13ATG13 autophagy related 13 homolog (S. cerevisiae)0.103
RASSF1Ras association (RalGDS/AF-6) domain family member 10.092
PSTPIP1proline-serine-threonine phosphatase interacting protein 10.085
VEGFAvascular endothelial growth factor A0.070
LUC7L2LUC7-like 2 (S. cerevisiae)0.068
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.068
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.067
STK4serine/threonine kinase 40.061
MAGI3membrane associated guanylate kinase, WW and PDZ domain containing 30.056
SPRR2Asmall proline-rich protein 2A0.056
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.055
MED28mediator complex subunit 280.053
NCOA6nuclear receptor coactivator 60.052
SCHIP1schwannomin interacting protein 10.049
NCOA2nuclear receptor coactivator 20.048
FSTL1follistatin-like 10.047
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.047
NXF1nuclear RNA export factor 10.047
FGFR2fibroblast growth factor receptor 20.046
SIRT1sirtuin 10.044
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.043
YAP1Yes-associated protein 10.042
SPG21spastic paraplegia 21 (autosomal recessive, Mast syndrome)0.041
TSC1tuberous sclerosis 10.041
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.037
CABLES1Cdk5 and Abl enzyme substrate 10.037
TGFB3transforming growth factor, beta 30.037
PDCD6IPprogrammed cell death 6 interacting protein0.037
BAIAP2BAI1-associated protein 20.037
MLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.036
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.036
CLASP1cytoplasmic linker associated protein 10.036
LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.032
SPG20spastic paraplegia 20 (Troyer syndrome)0.031
GAS7growth arrest-specific 70.030
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.029
RASSF3Ras association (RalGDS/AF-6) domain family member 30.029
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.027
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.022
PTENphosphatase and tensin homolog0.021
KAT2BK(lysine) acetyltransferase 2B0.020
COL4A3BPcollagen, type IV, alpha 3 (Goodpasture antigen) binding protein0.020
GRB2growth factor receptor-bound protein 20.020
GRB7growth factor receptor-bound protein 70.019
BTKBruton agammaglobulinemia tyrosine kinase0.019
MOBKL1BMOB1, Mps One Binder kinase activator-like 1B (yeast)0.019
SUV39H1suppressor of variegation 3-9 homolog 1 (Drosophila)0.019
CYFIP2cytoplasmic FMR1 interacting protein 20.019
SATB2SATB homeobox 20.019
BMP7bone morphogenetic protein 70.019
ITGB2integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)0.018
BTRCbeta-transducin repeat containing0.018
RASSF5Ras association (RalGDS/AF-6) domain family member 50.017
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.017
SMAD2SMAD family member 20.017
FASLGFas ligand (TNF superfamily, member 6)0.016
PTK2PTK2 protein tyrosine kinase 20.016
PTPRCprotein tyrosine phosphatase, receptor type, C0.016
INO80BINO80 complex subunit B0.016
RNF11ring finger protein 110.015
RB1CC1RB1-inducible coiled-coil 10.015
NCOA1nuclear receptor coactivator 10.015
FHL2four and a half LIM domains 20.015
SMAD7SMAD family member 70.015
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.015
PRKCZprotein kinase C, zeta0.015
FOXO1forkhead box O10.015
LCKlymphocyte-specific protein tyrosine kinase0.014
DCCdeleted in colorectal carcinoma0.014
PIAS4protein inhibitor of activated STAT, 40.014
TNKStankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase0.014
CREB1cAMP responsive element binding protein 10.014
AXIN1axin 10.014
FGF10fibroblast growth factor 100.013
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.013
WWOXWW domain containing oxidoreductase0.013
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.013
RB1retinoblastoma 10.013
APPL1adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 10.012
KRT5keratin 50.012
NCK1NCK adaptor protein 10.012
FAT1FAT tumor suppressor homolog 1 (Drosophila)0.012
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism