The network for 'cellular modified amino acid biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular modified amino acid biosynthetic process

The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents.

NameDescriptionProbabilityFunc Analog Organism
Txnrd1thioredoxin reductase 10.243
Ubqln1ubiquilin 10.196
Gclcglutamate-cysteine ligase, catalytic subunit0.188
Shmt1serine hydroxymethyltransferase 1 (soluble)0.174
Pgam2phosphoglycerate mutase 2 (muscle)0.152
Gclmglutamate cysteine ligase, modifier subunit0.123
Tstthiosulfate sulfurtransferase0.090
Aladaminolevulinate, delta-, dehydratase0.081
Slc25a10solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 100.067
Tfrctransferrin receptor0.065
Ahcyadenosylhomocysteinase0.060
Pecrperoxisomal trans-2-enoyl-CoA reductase0.058
Pctpphosphatidylcholine transfer protein0.057
Csnk2bcasein kinase 2, beta polypeptide0.057
Dph1DPH1 homolog (S. cerevisiae)0.056
Ugt1a6UDP glucuronosyltransferase 1 family, polypeptide A60.054
Sh3bgrSH3 domain binding glutamic acid-rich protein0.054
Me1malic enzyme 1, NADP(+)-dependent, cytosolic0.053
Hrsp12heat-responsive protein 120.052
Acy1aminoacylase 10.051
Tff3trefoil factor 3, intestinal0.051
Nqo1NAD(P)H dehydrogenase, quinone 10.048
Pygmphosphorylase, glycogen, muscle0.046
Hsd17b12hydroxysteroid (17-beta) dehydrogenase 120.045
Pygbphosphorylase, glycogen; brain0.043
Slc7a5solute carrier family 7 (cationic amino acid transporter, y+ system), member 50.043
Sf3b3splicing factor 3b, subunit 30.042
Mtpnmyotrophin0.040
Mgst3microsomal glutathione S-transferase 30.040
Cyp2d2cytochrome P450, family 2, subfamily d, polypeptide 20.039
Krt34keratin 340.039
UgdhUDP-glucose dehydrogenase0.039
LOC1003636626-phosphogluconate dehydrogenase, decarboxylating-like0.039
Gsta5glutathione S-transferase Yc2 subunit0.038
Coq10bcoenzyme Q10 homolog B (S. cerevisiae)0.037
Aldh4a1aldehyde dehydrogenase 4 family, member A10.036
Tecrtrans-2,3-enoyl-CoA reductase0.035
RGD1306682similar to RIKEN cDNA 1810046J190.035
Arl2ADP-ribosylation factor-like 20.035
Hsd17b11hydroxysteroid (17-beta) dehydrogenase 110.035
Atad3aATPase family, AAA domain containing 3A0.034
Rnps1ribonucleic acid binding protein S10.034
Hnf4ahepatocyte nuclear factor 4, alpha0.034
Arl5aADP-ribosylation factor-like 5A0.034
Gssglutathione synthetase0.032
Piglphosphatidylinositol glycan anchor biosynthesis, class L0.032
Mylpfmyosin light chain, phosphorylatable, fast skeletal muscle0.032
Desdesmin0.031
Srd5a1steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)0.031
Mapk6mitogen-activated protein kinase 60.029
Pacs1phosphofurin acidic cluster sorting protein 10.029
Unguracil-DNA glycosylase0.029
Ahraryl hydrocarbon receptor0.029
Akr7a3aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)0.029
Vtcn1V-set domain containing T cell activation inhibitor 10.028
Fen1flap structure-specific endonuclease 10.028
Lhcgrluteinizing hormone/choriogonadotropin receptor0.027
Akr7a2aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)0.027
Rpa2replication protein A20.027
Sult5a1sulfotransferase family 5A, member 10.026
Odc1ornithine decarboxylase 10.026
Psmd2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.026
Qprtquinolinate phosphoribosyltransferase0.025
Reep6receptor accessory protein 60.025
Ube4aubiquitination factor E4A (UFD2 homolog, yeast)0.025
RhdRh blood group, D antigen0.025
Mybbp1aMYB binding protein (P160) 1a0.025
Aldh7a1aldehyde dehydrogenase 7 family, member A10.024
Pgrmc1progesterone receptor membrane component 10.024
Nmuneuromedin U0.024
Hn1lhematological and neurological expressed 1-like0.024
Eif4heukaryotic translation initiation factor 4H0.023
Ccl28chemokine (C-C motif) ligand 280.023
Mef2dmyocyte enhancer factor 2D0.022
Polr1bpolymerase (RNA) I polypeptide B0.022
Hmbshydroxymethylbilane synthase0.022
Sfrs3splicing factor, arginine/serine-rich 30.022
Myl1myosin, light chain 10.022
Rnf5ring finger protein 50.022
Cyp2c23cytochrome P450, family 2, subfamily c, polypeptide 230.022
Pafah1b2platelet-activating factor acetylhydrolase, isoform 1b, subunit 20.022
Atp2a3ATPase, Ca++ transporting, ubiquitous0.021
Polr1epolymerase (RNA) I polypeptide E0.021
Cdcp1CUB domain containing protein 10.021
Pde5aphosphodiesterase 5A, cGMP-specific0.021
Fxyd4FXYD domain-containing ion transport regulator 40.021
Aldh18a1aldehyde dehydrogenase 18 family, member A10.021
Srxn1sulfiredoxin 1 homolog (S. cerevisiae)0.021
Exosc5exosome component 50.020
Phka1phosphorylase kinase, alpha 10.020
Catcatalase0.020
Dhrs7cdehydrogenase/reductase (SDR family) member 7C0.020
Shmt2serine hydroxymethyltransferase 2 (mitochondrial)0.020
Qdprquinoid dihydropteridine reductase0.019
Gja5gap junction protein, alpha 50.019
Josd2Josephin domain containing 20.019
Stub1STIP1 homology and U-Box containing protein 10.019
Aslargininosuccinate lyase0.019
Aqp9aquaporin 90.019
Stmn4stathmin-like 40.019
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
sams-3Protein SAMS-30.168
C53C9.2Protein C53C9.20.042
T22D1.3Protein T22D1.30.031
F55G1.5Protein F55G1.50.029
F22B5.10Protein F22B5.100.024
tram-1Protein TRAM-10.023
nduf-2.2Protein NDUF-2.20.022
sams-4Protein SAMS-40.020
F42G4.2Protein F42G4.20.020
mel-32Protein MEL-320.020
acs-5Protein ACS-50.018
asb-1Protein ASB-10.017
ssp-9Protein SSP-90.014
CELE_C01G12.3Protein C01G12.30.014
CELE_F36A4.1Protein F36A4.10.013
aagr-4Protein AAGR-40.013
iglr-2Protein IGLR-20.013
CELE_Y39G10AR.8Protein Y39G10AR.80.012
crm-1Protein CRM-10.012
arf-3Protein ARF-30.012
CELE_Y50E8A.2Protein Y50E8A.20.012
mthf-1Protein MTHF-10.012
apg-1Protein APG-10.012
cmd-1Protein CMD-10.011
trap-2Protein TRAP-20.011
CELE_Y57G11C.15Protein Y57G11C.150.011
ZK930.7Protein ZK930.70.011
CELE_Y75B8A.24Protein Y75B8A.240.011
Y48A6B.3Protein Y48A6B.30.011
mtrr-1Protein MTRR-10.011
ncbp-2Protein NCBP-20.011
CELE_F46F2.3Protein F46F2.30.010
ksr-1Protein KSR-10.010
CELE_F36D1.4Protein F36D1.40.010
tag-267Protein TAG-2670.010
ahcy-1Protein AHCY-10.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
GCLCglutamate-cysteine ligase, catalytic subunit0.662
GCLMglutamate-cysteine ligase, modifier subunit0.589
TFGTRK-fused gene0.446
SOD1superoxide dismutase 1, soluble0.351
PRDX1peroxiredoxin 10.197
NECAP2NECAP endocytosis associated 20.162
PLSCR4phospholipid scramblase 40.137
DLG2discs, large homolog 2 (Drosophila)0.125
SP100SP100 nuclear antigen0.075
CALCAcalcitonin-related polypeptide alpha0.061
PRDX2peroxiredoxin 20.049
METRNmeteorin, glial cell differentiation regulator0.046
STT3ASTT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)0.037
NDUFA1NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa0.035
CRY1cryptochrome 1 (photolyase-like)0.029
TXNthioredoxin0.028
MBNL1muscleblind-like (Drosophila)0.028
ATP5JATP synthase, H+ transporting, mitochondrial Fo complex, subunit F60.027
DAD1defender against cell death 10.026
ACLYATP citrate lyase0.026
MAPK3mitogen-activated protein kinase 30.025
LASP1LIM and SH3 protein 10.025
NONOnon-POU domain containing, octamer-binding0.024
MAGEA11melanoma antigen family A, 110.024
EIF2S3eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa0.023
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.023
NDUFA4NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa0.023
WWP1WW domain containing E3 ubiquitin protein ligase 10.021
NME4non-metastatic cells 4, protein expressed in0.021
PRDX4peroxiredoxin 40.020
AK2adenylate kinase 20.020
OSBPL8oxysterol binding protein-like 80.019
NTN4netrin 40.019
OCLNoccludin0.019
ME1malic enzyme 1, NADP(+)-dependent, cytosolic0.018
NAMPTnicotinamide phosphoribosyltransferase0.018
PPP3CAprotein phosphatase 3, catalytic subunit, alpha isozyme0.017
RHOXF2Rhox homeobox family, member 20.017
PRDX5peroxiredoxin 50.017
TCTN3tectonic family member 30.017
IFI16interferon, gamma-inducible protein 160.017
ERBB2IPerbb2 interacting protein0.016
DLG1discs, large homolog 1 (Drosophila)0.016
NEU4sialidase 40.016
FAM103A1family with sequence similarity 103, member A10.015
SRSF5serine/arginine-rich splicing factor 50.015
CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 10.015
ADCY7adenylate cyclase 70.014
CDK17cyclin-dependent kinase 170.014
RCC2regulator of chromosome condensation 20.014
MYLPFmyosin light chain, phosphorylatable, fast skeletal muscle0.013
SOD2superoxide dismutase 2, mitochondrial0.013
BANPBTG3 associated nuclear protein0.013
SDCBPsyndecan binding protein (syntenin)0.013
ADAM17ADAM metallopeptidase domain 170.013
TMED5transmembrane emp24 protein transport domain containing 50.013
SERPINB1serpin peptidase inhibitor, clade B (ovalbumin), member 10.012
ARL15ADP-ribosylation factor-like 150.012
C10orf10chromosome 10 open reading frame 100.012
TNNI2troponin I type 2 (skeletal, fast)0.011
PRDX6peroxiredoxin 60.011
HPD4-hydroxyphenylpyruvate dioxygenase0.011
KIAA0090KIAA00900.011
PHLDA1pleckstrin homology-like domain, family A, member 10.011
MAPK7mitogen-activated protein kinase 70.010
DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked0.010
PIRpirin (iron-binding nuclear protein)0.010
ZFAND2Bzinc finger, AN1-type domain 2B0.010
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Gclmglutamate-cysteine ligase, modifier subunit0.950
Gclcglutamate-cysteine ligase, catalytic subunit0.946
Ldb3LIM domain binding 30.171
Tcaptitin-cap0.149
Hrchistidine rich calcium binding protein0.117
Sgcasarcoglycan, alpha (dystrophin-associated glycoprotein)0.094
Gp9glycoprotein 9 (platelet)0.094
Casq1calsequestrin 10.076
Pgam2phosphoglycerate mutase 20.074
Actn2actinin alpha 20.064
Alox15arachidonate 15-lipoxygenase0.054
Rab25RAB25, member RAS oncogene family0.051
Cox8bcytochrome c oxidase, subunit VIIIb0.049
Apobec2apolipoprotein B mRNA editing enzyme, catalytic polypeptide 20.049
Tmem40transmembrane protein 400.049
Campcathelicidin antimicrobial peptide0.049
Mybphmyosin binding protein H0.042
Qdprquinoid dihydropteridine reductase0.039
Gcshglycine cleavage system protein H (aminomethyl carrier)0.035
Abp1amiloride binding protein 1 (amine oxidase, copper-containing)0.035
Myl3myosin, light polypeptide 30.034
Fbp2fructose bisphosphatase 20.034
Pgls6-phosphogluconolactonase0.032
Atp2a1ATPase, Ca++ transporting, cardiac muscle, fast twitch 10.032
Plin4perilipin 40.031
Krt15keratin 150.031
Fbp1fructose bisphosphatase 10.031
Rexo2REX2, RNA exonuclease 2 homolog (S. cerevisiae)0.030
Zfp385azinc finger protein 385A0.030
Thoc1THO complex 10.029
Agpat11-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)0.029
Adigadipogenin0.029
Art1ADP-ribosyltransferase 10.028
Xirp1xin actin-binding repeat containing 10.028
Myom2myomesin 20.028
Cox6a2cytochrome c oxidase, subunit VI a, polypeptide 20.028
Mthfd1methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase0.027
Galnt6UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 60.027
Retnresistin0.027
Padi1peptidyl arginine deiminase, type I0.026
Tnni2troponin I, skeletal, fast 20.026
Ltflactotransferrin0.025
Kcna7potassium voltage-gated channel, shaker-related subfamily, member 70.025
Pcxpyruvate carboxylase0.024
Itgb3integrin beta 30.024
Tnnt3troponin T3, skeletal, fast0.023
FcgbpFc fragment of IgG binding protein0.023
Reep6receptor accessory protein 60.022
Cratcarnitine acetyltransferase0.021
Sult2b1sulfotransferase family, cytosolic, 2B, member 10.020
Sit1suppression inducing transmembrane adaptor 10.020
Nrapnebulin-related anchoring protein0.020
Dctpp1dCTP pyrophosphatase 10.020
D17H6S56E-3DNA segment, Chr 17, human D6S56E 30.020
S100a3S100 calcium binding protein A30.019
Fbxo9f-box protein 90.019
Mrps25mitochondrial ribosomal protein S250.019
Dus1ldihydrouridine synthase 1-like (S. cerevisiae)0.019
Myh6myosin, heavy polypeptide 6, cardiac muscle, alpha0.019
Pnpopyridoxine 5'-phosphate oxidase0.019
Gsrglutathione reductase0.018
Fam83gfamily with sequence similarity 83, member G0.018
Dmpkdystrophia myotonica-protein kinase0.018
Ggt1gamma-glutamyltransferase 10.017
Tmem93transmembrane protein 930.017
Alpk3alpha-kinase 30.017
Myh2myosin, heavy polypeptide 2, skeletal muscle, adult0.017
Pebp1phosphatidylethanolamine binding protein 10.017
Fam83ffamily with sequence similarity 83, member F0.017
Slc25a45solute carrier family 25, member 450.017
Gykglycerol kinase0.017
Itgb1bp2integrin beta 1 binding protein 20.016
Clic3chloride intracellular channel 30.016
Ei24etoposide induced 2.4 mRNA0.016
Rif1Rap1 interacting factor 1 homolog (yeast)0.016
MdfiMyoD family inhibitor0.016
Starsteroidogenic acute regulatory protein0.015
Zfp335zinc finger protein 3350.015
Ltc4sleukotriene C4 synthase0.015
Tuba8tubulin, alpha 80.014
Pnliprp2pancreatic lipase-related protein 20.014
Gch1GTP cyclohydrolase 10.014
Aladaminolevulinate, delta-, dehydratase0.014
Mtch1mitochondrial carrier homolog 1 (C. elegans)0.014
Hspa8heat shock protein 80.014
Cideacell death-inducing DNA fragmentation factor, alpha subunit-like effector A0.014
Glo1glyoxalase 10.013
Lgals7lectin, galactose binding, soluble 70.013
Gpr132G protein-coupled receptor 1320.013
Phkg1phosphorylase kinase gamma 10.013
Col11a2collagen, type XI, alpha 20.013
Pparaperoxisome proliferator activated receptor alpha0.013
Ccl11chemokine (C-C motif) ligand 110.013
Tbxa2rthromboxane A2 receptor0.013
Mrpl28mitochondrial ribosomal protein L280.013
Actn3actinin alpha 30.013
Crct1cysteine-rich C-terminal 10.013
Stc2stanniocalcin 20.013
Ttntitin0.012
Mbmyoglobin0.012
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
ADE4Ade4p0.024
MET6Met6p0.021
YBR220Chypothetical protein0.020
CDS1Cds1p0.019
SDS3Sds3p0.018
ERG7Erg7p0.018
LCB2Lcb2p0.017
ADE5,7Ade5,7p0.015
TGL1Tgl1p0.015
TRM5Trm5p0.014
SPE3Spe3p0.014
OPT1Opt1p0.014
ERG8Erg8p0.013
YGR210Chypothetical protein0.013
CNE1Cne1p0.013
URA3Ura3p0.013
CKB1Ckb1p0.012
ADH6Adh6p0.012
BNA7Bna7p0.012
YML018Chypothetical protein0.012
YLR108Chypothetical protein0.012
EHT1Eht1p0.012
AST1Ast1p0.012
TSC3Tsc3p0.012
ADE13Ade13p0.012
RRT2Rrt2p0.012
IXR1Ixr1p0.011
YCR015Chypothetical protein0.011
ALT1Alt1p0.011
CHS1Chs1p0.011
ADE12Ade12p0.011
KAP104Kap104p0.011
VCX1Vcx1p0.011
YFR016Chypothetical protein0.011
ADH4Adh4p0.011
NIF3Nif3p0.011
YIR035Chypothetical protein0.011
YBL055Chypothetical protein0.011
IPT1Ipt1p0.011
COT1Cot1p0.011
CYS3Cys3p0.011
APT2Apt2p0.011
CHO2Cho2p0.011
PTK1Ptk1p0.011
YFR006Whypothetical protein0.011
GLN1Gln1p0.011
YGR017Whypothetical protein0.011
SRD1Srd1p0.011
BRN1Brn1p0.011
ARP10Arp10p0.010
MRS1Mrs1p0.010
PBP4Pbp4p0.010
SSP120Ssp120p0.010
MCX1Mcx1p0.010
YLR162Whypothetical protein0.010
ARG8Arg8p0.010
YLR057Whypothetical protein0.010
YOL098Chypothetical protein0.010
PRS2Prs2p0.010
FCY21Fcy21p0.010
TRP1Trp1p0.010
YKL023Whypothetical protein0.010
YLR264C-Ahypothetical protein0.010
OYE2Oye2p0.010
PUS6Pus6p0.010
ECT1Ect1p0.010
YOL038C-Ahypothetical protein0.010
MET8Met8p0.010