The network for 'regulation of mesenchymal cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of mesenchymal cell proliferation

Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.

NameDescriptionProbabilityFunc Analog Organism
Nek9NIMA (never in mitosis gene a)- related kinase 90.694
Tgfbr2transforming growth factor, beta receptor II0.537
Myo1cmyosin IC0.504
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.501
Parp14poly (ADP-ribose) polymerase family, member 140.499
Lamc1laminin, gamma 10.487
Gbp2guanylate binding protein 20.344
Myh9myosin, heavy chain 9, non-muscle0.329
Akt2v-akt murine thymoma viral oncogene homolog 20.326
Clic4chloride intracellular channel 40.324
Arntaryl hydrocarbon receptor nuclear translocator0.318
Unc5bunc-5 homolog B (C. elegans)0.266
Ddx58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.254
Itpr2inositol 1,4,5-triphosphate receptor, type 20.250
Calcrlcalcitonin receptor-like0.246
Ednraendothelin receptor type A0.241
Rnf213ring finger protein 2130.240
Stat1signal transducer and activator of transcription 10.238
Timp3TIMP metallopeptidase inhibitor 30.230
Eif2ak2eukaryotic translation initiation factor 2-alpha kinase 20.220
LOC100360403ATP-binding cassette, sub-family C, member 9-like0.203
Ptmaprothymosin alpha0.195
Acvr1activin A receptor, type I0.192
Smad7SMAD family member 70.189
Flt1FMS-related tyrosine kinase 10.185
Igtpinterferon gamma induced GTPase0.182
Igfbp5insulin-like growth factor binding protein 50.181
Prrx1paired related homeobox 10.167
Tceb3transcription elongation factor B (SIII), polypeptide 30.160
Irs1insulin receptor substrate 10.155
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.154
Itgb4integrin, beta 40.154
Smad1SMAD family member 10.153
Notch2Notch homolog 2 (Drosophila)0.148
Itga6integrin, alpha 60.144
Ifi35interferon-induced protein 350.143
Capn5calpain 50.140
Elovl5ELOVL family member 5, elongation of long chain fatty acids (yeast)0.138
Irf7interferon regulatory factor 70.131
Olfml2bolfactomedin-like 2B0.122
Map3k3mitogen activated protein kinase kinase kinase 30.118
LOC100362108poly (ADP-ribose) polymerase family, member 100.118
Sod3superoxide dismutase 3, extracellular0.114
Rxraretinoid X receptor alpha0.113
Nab1Ngfi-A binding protein 10.108
Gna12guanine nucleotide binding protein (G protein) alpha 120.105
Irgmimmunity-related GTPase family, M0.103
Lims1LIM and senescent cell antigen-like domains 10.100
Nr2f2nuclear receptor subfamily 2, group F, member 20.100
RT1-S3RT1 class Ib, locus S30.098
Elf1E74-like factor 10.093
Hdac7histone deacetylase 70.092
Lbrlamin B receptor0.091
Socs3suppressor of cytokine signaling 30.090
Smad3SMAD family member 30.088
Myo1bmyosin Ib0.087
Dtx3ldeltex 3-like (Drosophila)0.086
Epas1endothelial PAS domain protein 10.086
Glg1golgi apparatus protein 10.080
Fgfr2fibroblast growth factor receptor 20.079
Stx2syntaxin 20.077
Tcfe2atranscription factor E2a0.077
Metmet proto-oncogene0.076
Scarf2scavenger receptor class F, member 20.075
Pik3r1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.075
Irf9interferon regulatory factor 90.070
Ptpn14protein tyrosine phosphatase, non-receptor type 140.068
Nrasneuroblastoma ras oncogene0.067
Dhx9DEAH (Asp-Glu-Ala-His) box polypeptide 90.066
Gpamglycerol-3-phosphate acyltransferase, mitochondrial0.063
Antxr1anthrax toxin receptor 10.063
Sardhsarcosine dehydrogenase0.063
Efnb1ephrin B10.062
Pip4k2bphosphatidylinositol-5-phosphate 4-kinase, type II, beta0.061
Rtp4receptor (chemosensory) transporter protein 40.060
Ptprkprotein tyrosine phosphatase, receptor type, K, extracellular region0.060
NmiN-myc (and STAT) interactor0.060
Ednrbendothelin receptor type B0.058
Wnt5awingless-type MMTV integration site family, member 5A0.057
Irf1interferon regulatory factor 10.057
Plcg2phospholipase C, gamma 20.056
Tgfb2transforming growth factor, beta 20.056
Rab3il1RAB3A interacting protein (rabin3)-like 10.055
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.053
Gdf11growth differentiation factor 110.053
Srebf1sterol regulatory element binding transcription factor 10.052
Tcf3transcription factor 30.051
Frmd4bFERM domain containing 4B0.050
Crygbcrystallin, gamma B0.049
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.048
Gabra2gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 20.048
Trim5tripartite motif-containing 50.047
Glt25d1glycosyltransferase 25 domain containing 10.047
Nfyanuclear transcription factor-Y alpha0.047
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
dlx5adistal-less homeobox gene 5a0.828
dlx3bdistal-less homeobox gene 3b0.759
shhasonic hedgehog a0.669
nkx3.2NK3 homeobox 20.660
bocbrother of CDO0.623
bmp4bone morphogenetic protein 40.610
ptch1patched 10.523
bmp2bbone morphogenetic protein 2b0.507
hoxd4ahomeo box D4a0.459
fgfr4fibroblast growth factor receptor 40.386
sulf1sulfatase 10.355
fn1fibronectin 10.300
mab21l2mab-21-like 20.292
grem2gremlin 2, cysteine knot superfamily0.277
fgf10afibroblast growth factor 10a0.268
ndr2nodal-related 20.224
wif1wnt inhibitory factor 10.214
ptch2patched 20.206
bmp2abone morphogenetic protein 2a0.203
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.196
slit3slit (Drosophila) homolog 30.190
fgfrl1afibroblast growth factor receptor-like 1a0.187
fli1afriend leukemia integration 1a0.186
mmp15bmatrix metallopeptidase 15b0.184
itgavintegrin, alpha V0.167
col2a1acollagen type II, alpha-1a0.165
ptgs1prostaglandin-endoperoxide synthase 10.164
nkx2.5NK2 transcription factor related 50.162
pea3ETS-domain transcription factor pea30.157
hoxb5bhomeo box B5b0.152
mychmyelocytomatosis oncogene homolog0.147
sox9aSRY-box containing gene 9a0.138
ihhaIndian hedgehog homolog a0.128
pcdh18aprotocadherin 18a0.124
six4bsine oculis homeobox homolog 4b0.123
oprd1bopioid receptor, delta 1b0.122
col8a1acollagen, type VIII, alpha 1a0.122
fgf3fibroblast growth factor 30.122
fzd7afrizzled homolog 7a0.113
nkx2.1aNK2 homeobox 1a0.109
alpialkaline phosphatase, intestinal0.109
foxi1forkhead box I10.105
dlx4adistal-less homeobox gene 4a0.104
cdoncell adhesion molecule-related/down-regulated by oncogenes0.103
flt4fms-related tyrosine kinase 40.100
notch2notch homolog 20.098
wlswntless homolog (Drosophila)0.094
bmpr1abbone morphogenetic protein receptor, type 1ab0.093
jag1bjagged 1b0.093
flhfloating head0.092
cyp26b1cytochrome P450, family 26, subfamily b, polypeptide 10.092
foxa2forkhead box A20.091
tcf7transcription factor 7 (T-cell specific, HMG-box)0.089
wnt9awingless-type MMTV integration site family, member 9A0.086
bmp3bone morphogenetic protein 30.086
trpv4transient receptor potential cation channel, subfamily V, member 40.085
lef1lymphocyte enhancer binding factor 10.084
hand2heart and neural crest derivatives expressed transcript 20.083
pmp22aperipheral myelin protein 22a0.083
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.083
eya1eyes absent homolog 10.082
gli3GLI-Kruppel family member GLI30.079
pdgfaaplatelet-derived growth factor alpha a0.078
hoxc4ahomeo box C4a0.078
sema3aasemaphorin 3aa0.078
tie2endothelium-specific receptor tyrosine kinase 20.077
dlx1adistal-less homeobox gene 1a0.077
lhx2bLIM homeobox 2b0.076
runx2brunt-related transcription factor 2b0.076
nr2e1nuclear receptor subfamily 2, group E, member 10.075
msxdmuscle segment homeobox D0.074
rargaretinoic acid receptor gamma a0.074
foxa1forkhead box A10.073
myod1myogenic differentiation 10.072
arxaristaless related homeobox0.072
notch3notch homolog 30.072
col5a1procollagen, type V, alpha 10.070
angpt1angiopoietin 10.070
pitx2paired-like homeodomain transcription factor 20.067
emp2epithelial membrane protein 20.067
nkx2.3NK2 transcription factor related 30.067
rereaarginine-glutamic acid dipeptide (RE) repeats a0.066
dlx4bdistal-less homeobox gene 4b0.065
sox1aSRY-box containing gene 1a0.065
meis3myeloid ecotropic viral integration site 30.064
dlx2adistal-less homeobox gene 2a0.064
six2asine oculis-related homeobox 2a0.063
rbp4retinol binding protein 4, plasma0.062
hoxb6ahomeo box B6a0.061
dlx2bdistal-less homeobox gene 2b0.060
cxcl12bchemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)0.059
mef2camyocyte enhancer factor 2ca0.059
fzd7bfrizzled homolog 7b0.058
tie1endothelium-specific receptor tyrosine kinase 10.058
acvr1lactivin A receptor, type I like0.057
tnfsf10l3tumor necrosis factor (ligand) superfamily, member 10 like 30.057
irx5airoquois homeobox protein 5a0.056
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.964
INSRinsulin receptor0.876
BMPR1Abone morphogenetic protein receptor, type IA0.731
BMP2bone morphogenetic protein 20.451
NRP1neuropilin 10.395
GRB10growth factor receptor-bound protein 100.320
EGFRepidermal growth factor receptor0.311
FGF1fibroblast growth factor 1 (acidic)0.310
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.241
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.237
PTPN1protein tyrosine phosphatase, non-receptor type 10.149
APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)0.143
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.139
PLCG1phospholipase C, gamma 10.136
JUPjunction plakoglobin0.135
TCF4transcription factor 40.092
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.082
FSTL1follistatin-like 10.069
CDH5cadherin 5, type 2 (vascular endothelium)0.057
BMP1bone morphogenetic protein 10.044
FGF10fibroblast growth factor 100.042
APPamyloid beta (A4) precursor protein0.040
MAXMYC associated factor X0.038
CTBP1C-terminal binding protein 10.036
FGFR1fibroblast growth factor receptor 10.035
IGF1Rinsulin-like growth factor 1 receptor0.034
FGF2fibroblast growth factor 2 (basic)0.032
PDGFCplatelet derived growth factor C0.032
FZD1frizzled homolog 1 (Drosophila)0.029
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.028
SMAD3SMAD family member 30.028
CAV1caveolin 1, caveolae protein, 22kDa0.027
IRS1insulin receptor substrate 10.027
BTRCbeta-transducin repeat containing0.025
SHC2SHC (Src homology 2 domain containing) transforming protein 20.020
FGFR2fibroblast growth factor receptor 20.020
SOCS5suppressor of cytokine signaling 50.019
FGF7fibroblast growth factor 70.019
SATB2SATB homeobox 20.018
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.017
CABLES1Cdk5 and Abl enzyme substrate 10.015
DKK1dickkopf homolog 1 (Xenopus laevis)0.014
PGFplacental growth factor0.013
TGFB1transforming growth factor, beta 10.013
HOXD9homeobox D90.013
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.012
IRS2insulin receptor substrate 20.012
KRT5keratin 50.012
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.012
TCF7L2transcription factor 7-like 2 (T-cell specific, HMG-box)0.012
TGFB3transforming growth factor, beta 30.011
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.010
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Fgfr2fibroblast growth factor receptor 21.000
Tbx3T-box 30.999
Gli3GLI-Kruppel family member GLI30.998
Pax3paired box gene 30.998
Sox9SRY-box containing gene 90.995
Nos3nitric oxide synthase 3, endothelial cell0.994
Fgf10fibroblast growth factor 100.994
Prrx1paired related homeobox 10.992
Pax2paired box gene 20.991
Gli2GLI-Kruppel family member GLI20.991
Meox2mesenchyme homeobox 20.983
Fgf8fibroblast growth factor 80.982
Fgfr1fibroblast growth factor receptor 10.976
Wnt3awingless-related MMTV integration site 3A0.974
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.972
Zeb1zinc finger E-box binding homeobox 10.970
Ptenphosphatase and tensin homolog0.966
Pitx2paired-like homeodomain transcription factor 20.956
Gata4GATA binding protein 40.950
Bmp4bone morphogenetic protein 40.947
Hoxa1homeobox A10.927
Vegfavascular endothelial growth factor A0.909
Sox7SRY-box containing gene 70.900
Pitx1paired-like homeodomain transcription factor 10.894
Ror2receptor tyrosine kinase-like orphan receptor 20.888
Tgfb2transforming growth factor, beta 20.887
Foxc1forkhead box C10.877
Retret proto-oncogene0.858
Tbx15T-box 150.856
Col1a1collagen, type I, alpha 10.785
Twist2twist homolog 2 (Drosophila)0.771
Trp63transformation related protein 630.761
Alx4aristaless-like homeobox 40.755
Pax6paired box gene 60.748
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.720
Smad6MAD homolog 6 (Drosophila)0.716
Pax8paired box gene 80.712
Hoxd13homeobox D130.711
Hoxa13homeobox A130.710
Otx1orthodenticle homolog 1 (Drosophila)0.699
Fgfr3fibroblast growth factor receptor 30.689
Flt4FMS-like tyrosine kinase 40.683
Lhx1LIM homeobox protein 10.680
Sox2SRY-box containing gene 20.678
Rararetinoic acid receptor, alpha0.678
Cdh5cadherin 50.660
Apcadenomatosis polyposis coli0.653
Dkk1dickkopf homolog 1 (Xenopus laevis)0.645
Pou3f3POU domain, class 3, transcription factor 30.645
Rargretinoic acid receptor, gamma0.641
Tcf21transcription factor 210.633
Hoxd11homeobox D110.624
Tbx2T-box 20.624
Nr5a1nuclear receptor subfamily 5, group A, member 10.620
Hoxa11homeobox A110.620
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.602
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.601
Ghrgrowth hormone receptor0.595
Hand1heart and neural crest derivatives expressed transcript 10.580
Gdnfglial cell line derived neurotrophic factor0.559
Lrp6low density lipoprotein receptor-related protein 60.532
Tbx1T-box 10.523
Nkx2-1NK2 homeobox 10.522
Pou5f1POU domain, class 5, transcription factor 10.522
Msx1homeobox, msh-like 10.519
Wnt4wingless-related MMTV integration site 40.517
Nfibnuclear factor I/B0.485
Dlx5distal-less homeobox 50.463
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.460
Foxc2forkhead box C20.457
Amhr2anti-Mullerian hormone type 2 receptor0.452
Arandrogen receptor0.447
Fzd8frizzled homolog 8 (Drosophila)0.446
Tcfap2atranscription factor AP-2, alpha0.445
Kdrkinase insert domain protein receptor0.422
Ptpn11protein tyrosine phosphatase, non-receptor type 110.411
Isl1ISL1 transcription factor, LIM/homeodomain0.407
Slc9a3r2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.403
Ptprbprotein tyrosine phosphatase, receptor type, B0.403
Rarbretinoic acid receptor, beta0.391
Wt1Wilms tumor 1 homolog0.384
Runx2runt related transcription factor 20.378
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.368
Lmx1aLIM homeobox transcription factor 1 alpha0.356
Lef1lymphoid enhancer binding factor 10.356
Msx2homeobox, msh-like 20.345
Wnt5awingless-related MMTV integration site 5A0.342
Gata6GATA binding protein 60.342
En1engrailed 10.334
Shesrc homology 2 domain-containing transforming protein E0.333
Foxf1aforkhead box F1a0.332
Bmp7bone morphogenetic protein 70.331
Csf1colony stimulating factor 1 (macrophage)0.330
Sox11SRY-box containing gene 110.327
Pax7paired box gene 70.317
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism