The network for 'positive regulation of cellular catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of cellular catabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.

NameDescriptionProbabilityFunc Analog Organism
Junbjun B proto-oncogene0.249
FosFBJ osteosarcoma oncogene0.166
JunJun oncogene0.155
Btg2BTG family, member 20.147
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.129
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.128
Atf3activating transcription factor 30.121
Homer1homer homolog 1 (Drosophila)0.118
Myl9myosin, light chain 9, regulatory0.114
Pja2praja 2, RING-H2 motif containing0.107
Pctk2PCTAIRE protein kinase 20.103
Egr1early growth response 10.097
Prkcbprotein kinase C, beta0.086
Anxa2annexin A20.085
Zfp36zinc finger protein 360.084
Dusp1dual specificity phosphatase 10.081
Top2atopoisomerase (DNA) II alpha0.078
Pik3cdphosphoinositide-3-kinase, catalytic, delta polypeptide0.076
Egr2early growth response 20.074
Stip1stress-induced phosphoprotein 10.074
Syt4synaptotagmin IV0.073
Epas1endothelial PAS domain protein 10.065
Amphamphiphysin0.064
Cpt2carnitine palmitoyltransferase 20.063
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.063
Nr4a3nuclear receptor subfamily 4, group A, member 30.062
Rplp0ribosomal protein, large, P00.061
Arpc2actin related protein 2/3 complex, subunit 20.056
Arl1ADP-ribosylation factor-like 10.056
Anapc5anaphase-promoting complex subunit 50.056
Gria2glutamate receptor, ionotropic, AMPA 20.054
Kifc1kinesin family member C10.053
Zfp260zinc finger protein 2600.052
Myo1cmyosin IC0.051
Kcnab2potassium voltage-gated channel, shaker-related subfamily, beta member 20.051
Hk1hexokinase 10.051
Usf2upstream transcription factor 2, c-fos interacting0.049
Klf6Kruppel-like factor 60.049
Olr416olfactory receptor 4160.048
Atp1b2ATPase, Na+/K+ transporting, beta 2 polypeptide0.048
Gabrb3gamma-aminobutyric acid (GABA) A receptor, beta 30.048
Ccl22chemokine (C-C motif) ligand 220.047
Traf4af1TRAF4 associated factor 10.047
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.047
Eef2eukaryotic translation elongation factor 20.047
Racgap1Rac GTPase-activating protein 10.047
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)0.047
Dpp6dipeptidylpeptidase 60.046
Dusp5dual specificity phosphatase 50.046
Rph3arabphilin 3A0.045
Shank2SH3 and multiple ankyrin repeat domains 20.044
Mtus1mitochondrial tumor suppressor 10.043
Scn8asodium channel, voltage gated, type VIII, alpha subunit0.043
Ccne1cyclin E10.043
Tnftumor necrosis factor (TNF superfamily, member 2)0.042
Vegfbvascular endothelial growth factor B0.042
Lhx5LIM homeobox 50.041
Tarsthreonyl-tRNA synthetase0.041
Espnespin0.041
Gabra4gamma-aminobutyric acid (GABA) A receptor, alpha 40.041
Camk2acalcium/calmodulin-dependent protein kinase II alpha0.040
Phc1polyhomeotic homolog 1 (Drosophila)0.040
Errfi1ERBB receptor feedback inhibitor 10.040
Gng7guanine nucleotide binding protein (G protein), gamma 70.040
Ube2cubiquitin-conjugating enzyme E2C0.040
Ier2immediate early response 20.040
Cfpcomplement factor properdin0.040
Sncasynuclein, alpha (non A4 component of amyloid precursor)0.039
Tas2r119taste receptor, type 2, member 1190.039
Hand2heart and neural crest derivatives expressed 20.039
Usp19ubiquitin specific peptidase 190.039
Robo2roundabout homolog 2 (Drosophila)0.039
Chrm1cholinergic receptor, muscarinic 10.038
Lphn2latrophilin 20.038
Prrx1paired related homeobox 10.037
Egr3early growth response 30.036
Slc6a6solute carrier family 6 (neurotransmitter transporter, taurine), member 60.036
Mapk8ip1mitogen-activated protein kinase 8 interacting protein 10.036
Dusp6dual specificity phosphatase 60.036
Ccl3chemokine (C-C motif) ligand 30.036
Phf1PHD finger protein 10.036
Atp4bATPase, H+/K+ exchanging, beta polypeptide0.035
Epn1Epsin 10.035
Rac1ras-related C3 botulinum toxin substrate 10.035
Dlgap5discs, large (Drosophila) homolog-associated protein 50.035
Grifingalectin-related inter-fiber protein0.034
Pum1pumilio homolog 1 (Drosophila)0.034
Ceacam10carcinoembryonic antigen-related cell adhesion molecule 100.034
Vcsa1variable coding sequence A10.034
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.034
Eif4a2eukaryotic translation initiation factor 4A, isoform 20.033
Mdm2Mdm2 p53 binding protein homolog (mouse)0.033
Cap2CAP, adenylate cyclase-associated protein, 2 (yeast)0.033
Epha2Eph receptor A20.033
Slc6a9solute carrier family 6 (neurotransmitter transporter, glycine), member 90.033
Hpcahippocalcin0.033
Actbactin, beta0.033
Camk4calcium/calmodulin-dependent protein kinase IV0.033
Akap1A kinase (PRKA) anchor protein 10.032
Copb2coatomer protein complex, subunit beta 2 (beta prime)0.032
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
mpk-1Protein MPK-10.238
nhr-34Protein NHR-340.235
CELE_F47G4.4Protein F47G4.40.172
sem-5Protein SEM-50.167
atg-2Protein ATG-20.117
lin-36Protein LIN-360.113
unc-51Protein UNC-510.112
egl-18Protein EGL-180.106
elt-6Protein ELT-60.105
unc-62Protein UNC-620.104
mei-1Protein MEI-10.090
cas-1Protein CAS-10.089
F36D4.5Protein F36D4.50.088
trr-1Protein TRR-10.082
mrck-1Protein MRCK-10.071
scd-1Protein SCD-10.066
cks-1Protein CKS-10.065
atfs-1Protein ATFS-10.065
tpxl-1Protein TPXL-10.064
trcs-2Protein TRCS-20.063
egl-46Protein EGL-460.062
sax-3Protein SAX-30.062
cpr-4Protein CPR-40.058
rhgf-2Protein RHGF-20.057
stau-1Protein STAU-10.056
zoo-1Protein ZOO-10.054
imb-2Protein IMB-20.052
ptr-2Protein PTR-20.052
goa-1Protein GOA-10.051
mcm-7Protein MCM-70.051
toe-4Protein TOE-40.050
fntb-1Protein FNTB-10.050
F21A10.2Protein F21A10.20.049
let-607Protein LET-6070.048
imp-2Protein IMP-20.047
jnk-1Protein JNK-10.047
pat-12Protein PAT-120.046
Y55F3AM.9Protein Y55F3AM.90.046
C16A3.4Protein C16A3.40.046
nhr-6Protein NHR-60.045
Y71H2AM.20Protein Y71H2AM.200.045
cyld-1Protein CYLD-10.045
sams-4Protein SAMS-40.045
sli-1Protein SLI-10.045
zyg-9Protein ZYG-90.044
lin-48Protein LIN-480.044
dpl-1Protein DPL-10.043
ajm-1Protein AJM-10.043
mcm-2Protein MCM-20.043
rpn-1Protein RPN-10.043
ptp-1Protein PTP-10.042
lag-1Protein LAG-10.041
mat-3Protein MAT-30.041
rgl-1Protein RGL-10.041
CELE_Y41E3.11Protein Y41E3.110.041
trap-2Protein TRAP-20.040
pat-3Protein PAT-30.040
hsr-9Protein HSR-90.039
pkg-1Protein PKG-10.039
tag-343Protein TAG-3430.039
rme-4Protein RME-40.039
F52G3.1Protein F52G3.10.038
R90.1Protein R90.10.038
egl-8Protein EGL-80.038
vav-1Protein VAV-10.038
K08E3.5Protein K08E3.50.037
rnr-1Protein RNR-10.037
nhr-256Protein NHR-2560.037
magi-1Protein MAGI-10.037
smp-1Protein SMP-10.037
ttx-1Protein TTX-10.036
let-60Protein LET-600.036
cam-1Protein CAM-10.036
rab-5Protein RAB-50.036
cdc-48.2Protein CDC-48.20.035
klp-16Protein KLP-160.035
C11E4.6Protein C11E4.60.035
itr-1Protein ITR-10.034
ptp-3Protein PTP-30.034
sma-9Protein SMA-90.034
ubq-1Protein UBQ-10.034
F31C3.2Protein F31C3.20.034
ptp-4Protein PTP-40.034
eef-2Protein EEF-20.034
pme-3Protein PME-30.033
lon-2Protein LON-20.033
gei-8Protein GEI-80.033
abl-1Protein ABL-10.033
crt-1Protein CRT-10.033
spp-8Protein SPP-80.033
nhr-35Protein NHR-350.033
T14B1.1Protein T14B1.10.032
csn-1Protein CSN-10.032
gar-3Protein GAR-30.032
rpl-11.1Protein RPL-11.10.032
Y54E5A.7Protein Y54E5A.70.032
sea-2Protein SEA-20.031
rgs-7Protein RGS-70.031
F10B5.8Protein F10B5.80.031
F13E6.4Protein F13E6.40.031
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
foxa2forkhead box A20.658
hspa4aheat shock protein 4a0.407
hif1abhypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b0.399
cfl2lcofilin 2, like0.348
cnn2calponin 20.348
rtcd1RNA terminal phosphate cyclase domain 10.348
adrb2aadrenergic receptor, beta 2a0.344
tagln2transgelin 20.328
baxabcl2-associated X protein, a0.310
bcl2B-cell leukemia/lymphoma 20.309
junjun proto-oncogene0.302
ahctf1AT hook containing transcription factor 10.295
mcl1bmyeloid cell leukemia sequence 1b0.290
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.288
unc5bunc-5 homolog B (C. elegans)0.288
psen1presenilin 10.286
bmperBMP binding endothelial regulator0.282
si:dkey-233h2.3si:dkey-233h2.30.271
rtn1areticulon 1a0.251
dtngdystrobrevin, gamma and dystrobrevin, gamma-like0.249
ncor1nuclear receptor co-repressor 10.246
mxi1max interacting protein0.243
ccnb1cyclin B10.241
si:dkey-145p14.5si:dkey-145p14.50.226
ctnnb1catenin (cadherin-associated protein), beta 10.222
nf1aneurofibromin 1a0.220
smad2MAD homolog 2 (Drosophila)0.212
ilkintegrin linked kinase0.201
pak2ap21 (CDKN1A)-activated kinase 2a0.199
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.194
hnrnpkheterogeneous nuclear ribonucleoprotein K0.193
eomesaeomesodermin homolog a0.193
nanos3nanos homolog 30.191
mapre1lmicrotubule-associated protein, RP/EB family, member 1, like0.190
tp73tumor protein p730.189
pdlim1PDZ and LIM domain 1 (elfin)0.185
bidaBH3 interacting domain death agonist0.182
limk2LIM domain kinase 20.177
gata5GATA-binding protein 50.176
zgc:55891zgc:558910.176
dnmt4DNA (cytosine-5-)-methyltransferase 40.175
midnmidnolin0.175
kctd15apotassium channel tetramerisation domain containing 15a0.165
si:dkey-12o15.1si:dkey-12o15.10.164
dag1dystroglycan 10.162
nrasneuroblastoma RAS viral (v-ras) oncogene homolog0.159
tpm4tropomyosin 40.158
cited3Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 30.157
gna12guanine nucleotide binding protein (G protein) alpha 120.155
rasl11bRAS-like, family 11, member B0.155
gro2groucho 20.154
pole2polymerase (DNA directed), epsilon 20.152
sf3b1splicing factor 3b, subunit 10.152
csadcysteine sulfinic acid decarboxylase0.150
birc5abaculoviral IAP repeat-containing 5a0.149
foxo3bforkhead box O3b0.149
s100bS100 calcium binding protein, beta (neural)0.148
sirt1sirtuin (silent mating type information regulation 2 homolog) 10.147
depdc1aDEP domain containing 1a0.147
yes1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 10.145
dusp6dual specificity phosphatase 60.144
ccna2cyclin A20.143
hmgb1ahigh-mobility group box 1a0.142
klf4aKruppel-like transcription factor 4a0.141
bag6BCL2-associated athanogene 60.141
yap1Yes-associated protein 10.140
atp1b1bATPase, Na+/K+ transporting, beta 1b polypeptide0.139
arnt2aryl hydrocarbon receptor nuclear translocator 20.138
slc4a2asolute carrier family 4, anion exchanger, member 2a0.138
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.136
ccnb2cyclin B20.136
ccng1cyclin G10.136
mcl1amyeloid cell leukemia sequence 1a0.135
efnb2aephrin B2a0.134
si:dkey-7c22.2si:dkey-7c22.20.134
cul1acullin 1a0.133
hsp90a.2heat shock protein 90-alpha 20.132
csnk1dacasein kinase 1, delta a0.132
plxnb2aplexin b2a0.131
gpibglucose phosphate isomerase b0.130
stau1staufen, RNA binding protein, homolog 1 (Drosophila)0.130
c6complement component 60.129
rhoabras homolog gene family, member Ab0.127
tpst1tyrosylprotein sulfotransferase 10.127
cotl1coactosin-like 1 (Dictyostelium)0.127
plk1polo-like kinase 1 (Drosophila)0.126
zgc:153061zgc:1530610.125
acvr1bactivin A receptor, type IB0.125
hsp70lheat shock cognate 70-kd protein, like0.124
suv39h1bsuppressor of variegation 3-9 homolog 1b0.124
bcl2l10BCL2-like 10 (apoptosis facilitator)0.123
si:dkeyp-84f11.5si:dkeyp-84f11.50.123
adra2badrenergic, alpha-2B-, receptor0.122
slc25a25asolute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a0.122
chaf1bchromatin assembly factor 1, subunit B0.122
LOC100151531zinc finger protein Gfi-1b-like0.121
slc25a22solute carrier family 25 (mitochondrial carrier: glutamate), member 220.121
mecp2methyl CpG binding protein 20.121
cdiptCDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)0.121
tomm34translocase of outer mitochondrial membrane 340.120
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Pi3K92ECG4141 gene product from transcript CG4141-RB0.926
mspsmini spindles0.710
pucpuckered0.699
RhebCG1081 gene product from transcript CG1081-RA0.535
Stat92ESignal-transducer and activator of transcription protein at 92E0.506
Rac1CG2248 gene product from transcript CG2248-RA0.503
Atg18Autophagy-specific gene 180.466
Dcr-2Dicer-20.457
PknProtein kinase related to protein kinase N0.453
dysdysfusion0.406
RhoGAP68FCG6811 gene product from transcript CG6811-RA0.376
Hnf4Hepatocyte nuclear factor 40.341
14-3-3epsilonCG31196 gene product from transcript CG31196-RA0.337
Su(H)Suppressor of Hairless0.321
dmdiminutive0.312
cenG1Acentaurin gamma 1A0.309
Dhc64CDynein heavy chain 64C0.288
MerMerlin0.281
ctaconcertina0.280
HrsHepatocyte growth factor regulated tyrosine kinase substrate0.263
Atg13Autophagy-specific gene 130.257
Rho1CG8416 gene product from transcript CG8416-RB0.253
dosdaughter of sevenless0.245
NNotch0.241
Ras85DRas oncogene at 85D0.241
MarfMitochondrial assembly regulatory factor0.238
Akt1CG4006 gene product from transcript CG4006-RA0.235
aubaubergine0.235
rprreaper0.228
LnkCG17367 gene product from transcript CG17367-RC0.218
CG11486CG11486 gene product from transcript CG11486-RG0.215
carcarnation0.210
bskbasket0.209
Itp-r83AInositol 1,4,5,-tris-phosphate receptor0.207
Top1Topoisomerase 10.200
htlheartless0.188
dikdiskette0.187
shishibire0.185
trioCG18214 gene product from transcript CG18214-RA0.177
Su(dx)Suppressor of deltex0.177
Sin3ACG8815 gene product from transcript CG8815-RC0.177
CycACyclin A0.172
simasimilar0.170
Ced-12CG5336 gene product from transcript CG5336-RA0.168
Trim9CG31721 gene product from transcript CG31721-RB0.162
chicchickadee0.155
NaCP60ENa channel protein 60E0.154
CG4771CG4771 gene product from transcript CG4771-RA0.152
stgstring0.151
ykiyorkie0.146
rlrolled0.143
neurneuralized0.142
mtsmicrotubule star0.141
MtlMig-2-like0.139
mei-41meiotic 410.137
Mekk1CG7717 gene product from transcript CG7717-RB0.136
cnocanoe0.134
shgshotgun0.134
Top3alphaTopoisomerase 3alpha0.132
RhoGAP93BCG3421 gene product from transcript CG3421-RA0.131
eIF-4EEukaryotic initiation factor 4E0.130
RhoGEF2CG9635 gene product from transcript CG9635-RF0.130
gwlgreatwall0.129
PtenCG5671 gene product from transcript CG5671-RB0.127
CG1021CG1021 gene product from transcript CG1021-RE0.126
rokRho-kinase0.125
Smg1CG32743 gene product from transcript CG32743-RA0.124
Hr96Hormone receptor-like in 960.122
Toll-7CG8595 gene product from transcript CG8595-RA0.121
EcREcdysone receptor0.120
WnkCG7177 gene product from transcript CG7177-RA0.119
SmoxSmad on X0.119
drkdownstream of receptor kinase0.119
feofascetto0.119
Gap69CGTPase-activating protein 69C0.118
gekgenghis khan0.115
spinspinster0.114
Pk61CProtein kinase 61C0.113
HLH106Helix loop helix protein 1060.112
mus209mutagen-sensitive 2090.110
edlETS-domain lacking0.109
drprdraper0.109
rinrasputin0.108
cpacapping protein alpha0.108
InRInsulin-like receptor0.107
Orc2Origin recognition complex subunit 20.106
pxplexus0.105
jarjaguar0.104
S6kRPS6-p70-protein kinase0.103
msnmisshapen0.102
rhirhino0.100
l(2)k16918lethal (2) k169180.100
Sir2CG5216 gene product from transcript CG5216-RA0.100
GitCG16728 gene product from transcript CG16728-RA0.100
tmodtropomodulin0.099
KlcKinesin light chain0.098
sharkSrc homology 2, ankyrin repeat, tyrosine kinase0.098
G-ialpha65AG protein alphai subunit 65A0.098
dupdouble parked0.097
Dap160Dynamin associated protein 1600.096
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.999
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.998
SQSTM1sequestosome 10.997
MDM2Mdm2 p53 binding protein homolog (mouse)0.996
DNM2dynamin 20.989
HTThuntingtin0.982
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.979
RB1retinoblastoma 10.960
SMURF2SMAD specific E3 ubiquitin protein ligase 20.960
BCL2B-cell CLL/lymphoma 20.956
SMAD3SMAD family member 30.956
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.954
UBCubiquitin C0.954
IGF1Rinsulin-like growth factor 1 receptor0.951
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.933
NCF2neutrophil cytosolic factor 20.929
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.929
EGFRepidermal growth factor receptor0.928
BCL2L1BCL2-like 10.924
SMAD2SMAD family member 20.917
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.898
MDM4Mdm4 p53 binding protein homolog (mouse)0.874
ARRB1arrestin, beta 10.870
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.869
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.867
JUNjun proto-oncogene0.867
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.851
SMAD4SMAD family member 40.846
TOB1transducer of ERBB2, 10.834
BCAR1breast cancer anti-estrogen resistance 10.829
FGFR2fibroblast growth factor receptor 20.824
TNRC6Atrinucleotide repeat containing 6A0.816
SMAD7SMAD family member 70.804
SFNstratifin0.794
RHOAras homolog gene family, member A0.792
S100A11S100 calcium binding protein A110.789
S100A6S100 calcium binding protein A60.786
SHC1SHC (Src homology 2 domain containing) transforming protein 10.780
CDC27cell division cycle 27 homolog (S. cerevisiae)0.774
EXOSC3exosome component 30.768
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.759
BBS10Bardet-Biedl syndrome 100.752
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.739
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.733
CDC20cell division cycle 20 homolog (S. cerevisiae)0.731
SH3RF1SH3 domain containing ring finger 10.711
EXOSC10exosome component 100.680
PTK2PTK2 protein tyrosine kinase 20.679
SNX9sorting nexin 90.679
RAC2ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)0.673
MAP3K5mitogen-activated protein kinase kinase kinase 50.657
FGFR1fibroblast growth factor receptor 10.654
RIN3Ras and Rab interactor 30.651
MAP2K4mitogen-activated protein kinase kinase 40.651
SMAD1SMAD family member 10.650
DUSP1dual specificity phosphatase 10.631
FASLGFas ligand (TNF superfamily, member 6)0.626
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.625
S100A4S100 calcium binding protein A40.611
SH3KBP1SH3-domain kinase binding protein 10.601
FOSFBJ murine osteosarcoma viral oncogene homolog0.596
CSNK1Ecasein kinase 1, epsilon0.578
GRB10growth factor receptor-bound protein 100.577
ADRBK1adrenergic, beta, receptor kinase 10.576
EXOSC7exosome component 70.574
ATG3ATG3 autophagy related 3 homolog (S. cerevisiae)0.565
GIT1G protein-coupled receptor kinase interacting ArfGAP 10.563
BADBCL2-associated agonist of cell death0.558
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.558
BCL2L11BCL2-like 11 (apoptosis facilitator)0.553
SKILSKI-like oncogene0.548
CSNK1Dcasein kinase 1, delta0.543
NEDD4neural precursor cell expressed, developmentally down-regulated 40.543
PSEN1presenilin 10.539
SMAD5SMAD family member 50.535
LAMTOR1late endosomal/lysosomal adaptor, MAPK and MTOR activator 10.534
S100A8S100 calcium binding protein A80.532
SYNJ1synaptojanin 10.530
ARFGEF1ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)0.528
DVL1dishevelled, dsh homolog 1 (Drosophila)0.527
DVL3dishevelled, dsh homolog 3 (Drosophila)0.516
IRS2insulin receptor substrate 20.509
MAPTmicrotubule-associated protein tau0.509
GABARAPL1GABA(A) receptor-associated protein like 10.507
FKBP4FK506 binding protein 4, 59kDa0.505
LRRK2leucine-rich repeat kinase 20.502
NCK2NCK adaptor protein 20.501
HIPK2homeodomain interacting protein kinase 20.501
PLK1polo-like kinase 10.493
NCLnucleolin0.491
MARK3MAP/microtubule affinity-regulating kinase 30.488
S100BS100 calcium binding protein B0.486
RALAv-ral simian leukemia viral oncogene homolog A (ras related)0.483
DNM1dynamin 10.483
PKN3protein kinase N30.482
ZFYVE9zinc finger, FYVE domain containing 90.464
TP53tumor protein p530.453
EPS15epidermal growth factor receptor pathway substrate 150.452
NCKAP1NCK-associated protein 10.444
HSPA5heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)0.426
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ctnnb1catenin (cadherin associated protein), beta 10.989
Pnpla2patatin-like phospholipase domain containing 20.988
Grb2growth factor receptor bound protein 20.959
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.939
Ppargperoxisome proliferator activated receptor gamma0.913
Efnb2ephrin B20.874
Gsk3bglycogen synthase kinase 3 beta0.848
Rac1RAS-related C3 botulinum substrate 10.841
Plxna1plexin A10.828
BrafBraf transforming gene0.827
Git1G protein-coupled receptor kinase-interactor 10.813
Ptenphosphatase and tensin homolog0.811
Pafah1b1platelet-activating factor acetylhydrolase, isoform 1b, subunit 10.800
Axin1axin 10.800
Foxo1forkhead box O10.787
Mdm2transformed mouse 3T3 cell double minute 20.785
Hmha1histocompatibility (minor) HA-10.784
Itsn1intersectin 1 (SH3 domain protein 1A)0.774
Ccna2cyclin A20.762
Adam19a disintegrin and metallopeptidase domain 19 (meltrin beta)0.747
Dlg4discs, large homolog 4 (Drosophila)0.745
Klklotho0.741
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.730
Cyldcylindromatosis (turban tumor syndrome)0.718
Trp73transformation related protein 730.718
Arrb2arrestin, beta 20.705
Trp53transformation related protein 530.700
Mki67antigen identified by monoclonal antibody Ki 670.676
Ccnb2cyclin B20.654
Hdac7histone deacetylase 70.652
Usp9xubiquitin specific peptidase 9, X chromosome0.649
Vav1vav 1 oncogene0.641
Per2period homolog 2 (Drosophila)0.633
Rasgrp2RAS, guanyl releasing protein 20.631
Arhgef11Rho guanine nucleotide exchange factor (GEF) 110.618
Gfra2glial cell line derived neurotrophic factor family receptor alpha 20.604
Plxnb1plexin B10.599
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.598
Nf1neurofibromatosis 10.586
Gata5GATA binding protein 50.577
Tspan9tetraspanin 90.569
Pim1proviral integration site 10.568
Lepleptin0.565
Ptk2bPTK2 protein tyrosine kinase 2 beta0.564
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.561
Ccnb1cyclin B10.555
Ranbp9RAN binding protein 90.553
Tsc1tuberous sclerosis 10.534
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.532
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.520
Atf2activating transcription factor 20.518
Adrb1adrenergic receptor, beta 10.514
Socs1suppressor of cytokine signaling 10.513
Selplgselectin, platelet (p-selectin) ligand0.509
Appamyloid beta (A4) precursor protein0.508
Insrinsulin receptor0.505
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.504
Laptm5lysosomal-associated protein transmembrane 50.500
Dctn1dynactin 10.497
Asap1ArfGAP with SH# domain, ankyrin repeat and PH domain10.476
Nrp1neuropilin 10.476
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.475
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.472
Pde1bphosphodiesterase 1B, Ca2+-calmodulin dependent0.470
Irs2insulin receptor substrate 20.464
Akt1thymoma viral proto-oncogene 10.463
Ciccapicua homolog (Drosophila)0.457
Tbx3T-box 30.451
Adam11a disintegrin and metallopeptidase domain 110.436
Klf3Kruppel-like factor 3 (basic)0.427
Cdk1cyclin-dependent kinase 10.426
Atxn7l3ataxin 7-like 30.426
Efna1ephrin A10.422
Chrm1cholinergic receptor, muscarinic 1, CNS0.421
Mapk8ip3mitogen-activated protein kinase 8 interacting protein 30.417
Lystlysosomal trafficking regulator0.411
Prkcdprotein kinase C, delta0.411
Kcnab2potassium voltage-gated channel, shaker-related subfamily, beta member 20.401
Tnfsf14tumor necrosis factor (ligand) superfamily, member 140.400
Adam9a disintegrin and metallopeptidase domain 9 (meltrin gamma)0.396
Jag2jagged 20.396
Bglapbone gamma carboxyglutamate protein0.395
Rhobras homolog gene family, member B0.391
Epha4Eph receptor A40.390
Gfra1glial cell line derived neurotrophic factor family receptor alpha 10.384
Nr3c1nuclear receptor subfamily 3, group C, member 10.379
Irf5interferon regulatory factor 50.375
Pdpk13-phosphoinositide dependent protein kinase 10.374
Atf4activating transcription factor 40.373
Smurf2SMAD specific E3 ubiquitin protein ligase 20.368
Cd37CD37 antigen0.367
Trim32tripartite motif-containing 320.367
Phlpp1PH domain and leucine rich repeat protein phosphatase 10.367
Mapk14mitogen-activated protein kinase 140.365
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.361
Leprleptin receptor0.358
Ppp1r9bprotein phosphatase 1, regulatory subunit 9B0.357
Scn5asodium channel, voltage-gated, type V, alpha0.354
Ccne1cyclin E10.354
Epha1Eph receptor A10.353
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
MIG1Mig1p0.158
RHO1Rho1p0.156
STE11Ste11p0.153
SPA2Spa2p0.135
BEM4Bem4p0.123
GYL1Gyl1p0.120
HSV2Hsv2p0.119
DCP2Dcp2p0.115
CDC16Cdc16p0.112
YDJ1Ydj1p0.111
GRR1Grr1p0.105
KEM1Kem1p0.100
BCY1Bcy1p0.100
RAD23Rad23p0.099
VAC7Vac7p0.095
ROM2Rom2p0.093
SLT2Slt2p0.093
PUB1Pub1p0.091
CDC23Cdc23p0.083
HSL1Hsl1p0.083
NTO1Nto1p0.082
SWC4Swc4p0.081
STE20Ste20p0.081
SUI2Sui2p0.080
MOB1Mob1p0.078
SUI3Sui3p0.076
TOM1Tom1p0.075
MNN9Mnn9p0.074
YAK1Yak1p0.072
SEC3Sec3p0.070
HMO1Hmo1p0.068
BEM3Bem3p0.068
TUS1Tus1p0.067
YTA7Yta7p0.067
RPN14Rpn14p0.066
GCD6Gcd6p0.066
RAD14Rad14p0.065
MKK1Mkk1p0.065
CAK1Cak1p0.064
GLN3Gln3p0.064
ITC1Itc1p0.062
ATG3Atg3p0.062
RGA2Rga2p0.061
CDC12Cdc12p0.061
PIP2Pip2p0.061
MET4Met4p0.060
RTT106Rtt106p0.060
UBP14Ubp14p0.059
HHO1Hho1p0.059
MIG2Mig2p0.058
VPS27Vps27p0.058
TAO3Tao3p0.057
PCL2Pcl2p0.057
AVO1Avo1p0.057
CKS1Cks1p0.056
UBR1Ubr1p0.056
PTP2Ptp2p0.056
UFO1Ufo1p0.056
RPT3Rpt3p0.056
DST1Dst1p0.054
SSC1Ssc1p0.054
BRO1Bro1p0.054
MYO4Myo4p0.053
VID28Vid28p0.053
MOB2Mob2p0.052
ATG13Atg13p0.052
STI1Sti1p0.052
DHH1Dhh1p0.052
YML081Whypothetical protein0.052
GDS1Gds1p0.051
VPS41Vps41p0.049
AFT1Aft1p0.049
YPT53Ypt53p0.048
CYC8Cyc8p0.048
VPS4Vps4p0.048
GCD7Gcd7p0.047
MIG3Mig3p0.047
YIP4Yip4p0.047
PKP2Pkp2p0.047
FIG4Fig4p0.046
YAP1Yap1p0.045
SET2Set2p0.045
HXT3Hxt3p0.044
VMA8Vma8p0.044
BNI4Bni4p0.044
YPT31Ypt31p0.044
PDE2Pde2p0.044
APC2Apc2p0.044
MDM10Mdm10p0.044
PXA1Pxa1p0.043
SSA4Ssa4p0.043
TPK3Tpk3p0.043
FAA2Faa2p0.043
KIC1Kic1p0.043
SEC16Sec16p0.043
YLR455Whypothetical protein0.042
MMS21Mms21p0.042
LYS5Lys5p0.042
MON1Mon1p0.041
SAS5Sas5p0.041