The network for 'response to sterol' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to sterol

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus.

NameDescriptionProbabilityFunc Analog Organism
Sc4molsterol-C4-methyl oxidase-like0.473
Idi1isopentenyl-diphosphate delta isomerase 10.412
DbpD site of albumin promoter (albumin D-box) binding protein0.139
Fdpsfarnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)0.127
Nr1d2nuclear receptor subfamily 1, group D, member 20.117
Fdft1farnesyl diphosphate farnesyl transferase 10.078
Sqlesqualene epoxidase0.060
Acat3acetyl-Coenzyme A acetyltransferase 30.050
Fcn1ficolin (collagen/fibrinogen domain containing) 10.047
C1qccomplement component 1, q subcomponent, C chain0.041
Il1ainterleukin 1 alpha0.038
Il1binterleukin 1 beta0.031
Tmem176btransmembrane protein 176B0.029
Il2rbinterleukin 2 receptor, beta0.029
Cd86CD86 molecule0.025
FcgrtFc fragment of IgG, receptor, transporter, alpha0.024
Stat6signal transducer and activator of transcription 60.022
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.022
Cyp51cytochrome P450, family 510.022
Cd14CD14 molecule0.022
Anpepalanyl (membrane) aminopeptidase0.021
Ephx1epoxide hydrolase 1, microsomal0.020
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.020
Insig1insulin induced gene 10.019
Il1rninterleukin 1 receptor antagonist0.019
Cfdcomplement factor D (adipsin)0.018
Cldn7claudin 70.018
Cst3cystatin C0.017
Slc6a12solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 120.017
Mvdmevalonate (diphospho) decarboxylase0.017
Aspgasparaginase homolog (S. cerevisiae)0.017
Prf1perforin 1 (pore forming protein)0.016
Mmp3matrix metallopeptidase 30.016
Hmgcr3-hydroxy-3-methylglutaryl-Coenzyme A reductase0.016
Cd68Cd68 molecule0.015
Serpinb2serpin peptidase inhibitor, clade B (ovalbumin), member 20.015
TcrbT-cell receptor beta chain0.015
Il1r2interleukin 1 receptor, type II0.015
Masp2mannan-binding lectin serine peptidase 20.015
Hpgdshematopoietic prostaglandin D synthase0.015
Prrx1paired related homeobox 10.014
Inmtindolethylamine N-methyltransferase0.014
Mmp12matrix metallopeptidase 120.013
Klrd1killer cell lectin-like receptor, subfamily D, member 10.013
B4galt1UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 10.013
Fut4fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)0.013
Cd200r1CD200 receptor 10.013
Cela1chymotrypsin-like elastase family, member 10.012
Nox4NADPH oxidase 40.012
Hebp1heme binding protein 10.012
Sult1a1sulfotransferase family, cytosolic, 1A, phenol-preferring, member 10.012
Ppap2bphosphatidic acid phosphatase type 2B0.012
Man2b1mannosidase, alpha, class 2B, member 10.012
Smad7SMAD family member 70.011
Mpeg1macrophage expressed 10.011
Cdh17cadherin 170.011
Hmgcs13-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)0.011
Fcer1aFc fragment of IgE, high affinity I, receptor for; alpha polypeptide0.011
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.011
Nkg7natural killer cell group 7 sequence0.010
Ppargperoxisome proliferator-activated receptor gamma0.010
Sellselectin L0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
BRWD3CG31132 gene product from transcript CG31132-RA0.611
EcREcdysone receptor0.511
ftz-f1ftz transcription factor 10.507
CG5146CG5146 gene product from transcript CG5146-RA0.371
ash1absent, small, or homeotic discs 10.320
fkhfork head0.191
fnefound in neurons0.178
gcmglial cells missing0.157
Sir2CG5216 gene product from transcript CG5216-RA0.151
CG5741CG5741 gene product from transcript CG5741-RC0.148
bwabrain washing0.130
Trf2TATA box binding protein-related factor 20.125
Gyc76CGuanylyl cyclase at 76C0.124
Jarid2CG3654 gene product from transcript CG3654-RD0.122
Tao-1CG14217 gene product from transcript CG14217-RF0.117
E(bx)Enhancer of bithorax0.111
Top1Topoisomerase 10.110
HLH54FCG5005 gene product from transcript CG5005-RA0.102
nkdnaked cuticle0.101
myoglianinCG1838 gene product from transcript CG1838-RD0.101
Bre1CG10542 gene product from transcript CG10542-RA0.100
Eip74EFEcdysone-induced protein 74EF0.097
IswiImitation SWI0.094
CG14869CG14869 gene product from transcript CG14869-RB0.089
CG1347CG1347 gene product from transcript CG1347-RB0.084
Pkc98EProtein C kinase 98E0.082
toytwin of eyeless0.077
hydhyperplastic discs0.075
CG6490CG6490 gene product from transcript CG6490-RB0.073
CG17018CG17018 gene product from transcript CG17018-RC0.072
SuURSuppressor of Under-Replication0.070
Su(var)2-10Suppressor of variegation 2-100.070
Ten-aTenascin accessory0.070
jebjelly belly0.066
RhoGAPp190CG32555 gene product from transcript CG32555-RB0.063
CG11399CG11399 gene product from transcript CG11399-RB0.063
Exp6Exportin 60.060
CG8709CG8709 gene product from transcript CG8709-RK0.060
TbhTyramine beta hydroxylase0.059
l(3)mbtlethal (3) malignant brain tumor0.055
eastenhanced adult sensory threshold0.055
MED31Mediator complex subunit 310.054
Hr51Hormone receptor 510.052
snostrawberry notch0.051
slmbsupernumerary limbs0.051
cdicenter divider0.050
endoBendophilin B0.049
Top2Topoisomerase 20.048
Nf1Neurofibromin 10.048
PargPoly(ADP-ribose) glycohydrolase0.048
CG3638CG3638 gene product from transcript CG3638-RE0.048
sogshort gastrulation0.047
Sin3ACG8815 gene product from transcript CG8815-RC0.046
Eip75BEcdysone-induced protein 75B0.045
Hsc70-4Heat shock protein cognate 40.045
mei-P26CG12218 gene product from transcript CG12218-RA0.045
CG34400CG34400 gene product from transcript CG34400-RD0.044
CG5591CG5591 gene product from transcript CG5591-RA0.044
HDAC4CG1770 gene product from transcript CG1770-RE0.044
Upf1CG1559 gene product from transcript CG1559-RA0.043
Wnt2Wnt oncogene analog 20.043
PsiP-element somatic inhibitor0.042
eveeven skipped0.042
MED24Mediator complex subunit 240.039
ScmSex comb on midleg0.039
Ctr1BCopper transporter 1B0.038
MED6Mediator complex subunit 60.038
PtpmegCG1228 gene product from transcript CG1228-RD0.037
ph-dpolyhomeotic distal0.037
tauCG31057 gene product from transcript CG31057-RA0.037
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
SMAD2SMAD family member 20.999
SMAD7SMAD family member 70.999
CCR5chemokine (C-C motif) receptor 50.997
SMURF2SMAD specific E3 ubiquitin protein ligase 20.907
CCL4chemokine (C-C motif) ligand 40.865
FKBP1AFK506 binding protein 1A, 12kDa0.723
APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)0.713
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.678
SMAD3SMAD family member 30.514
NR0B1nuclear receptor subfamily 0, group B, member 10.494
CXCL9chemokine (C-X-C motif) ligand 90.428
TGFB1transforming growth factor, beta 10.398
CCR7chemokine (C-C motif) receptor 70.352
CCL8chemokine (C-C motif) ligand 80.327
TGFBR1transforming growth factor, beta receptor 10.304
IFNGinterferon, gamma0.294
BMP2bone morphogenetic protein 20.275
CCL5chemokine (C-C motif) ligand 50.272
CCR4chemokine (C-C motif) receptor 40.264
FSTL1follistatin-like 10.221
CCL22chemokine (C-C motif) ligand 220.212
CCL3chemokine (C-C motif) ligand 30.209
SMAD1SMAD family member 10.203
GDF5growth differentiation factor 50.202
IL2RBinterleukin 2 receptor, beta0.193
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.190
ACVR1activin A receptor, type I0.161
IL1Binterleukin 1, beta0.127
CCL7chemokine (C-C motif) ligand 70.114
SMAD5SMAD family member 50.106
CCL19chemokine (C-C motif) ligand 190.098
CCL13chemokine (C-C motif) ligand 130.094
IL8interleukin 80.087
TGFB3transforming growth factor, beta 30.086
SMAD4SMAD family member 40.085
ZNF148zinc finger protein 1480.081
CXCR6chemokine (C-X-C motif) receptor 60.072
VEZF1vascular endothelial zinc finger 10.069
CXCL13chemokine (C-X-C motif) ligand 130.066
IRF4interferon regulatory factor 40.062
PCGF2polycomb group ring finger 20.057
LTAlymphotoxin alpha (TNF superfamily, member 1)0.056
CCL2chemokine (C-C motif) ligand 20.055
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.054
CCL18chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)0.053
CCR2chemokine (C-C motif) receptor 20.049
SMURF1SMAD specific E3 ubiquitin protein ligase 10.048
REREarginine-glutamic acid dipeptide (RE) repeats0.047
CXXC5CXXC finger protein 50.044
IL6interleukin 6 (interferon, beta 2)0.043
IL1R2interleukin 1 receptor, type II0.043
TNFtumor necrosis factor0.042
PRRC2Bproline-rich coiled-coil 2B0.039
SCMH1sex comb on midleg homolog 1 (Drosophila)0.038
CCL11chemokine (C-C motif) ligand 110.038
CD40LGCD40 ligand0.035
SMAD6SMAD family member 60.034
PRKG1protein kinase, cGMP-dependent, type I0.032
SLAMF7SLAM family member 70.031
ACVR1Bactivin A receptor, type IB0.028
BAZ1Abromodomain adjacent to zinc finger domain, 1A0.025
SMOsmoothened homolog (Drosophila)0.025
RGS1regulator of G-protein signaling 10.025
CXCL3chemokine (C-X-C motif) ligand 30.025
CCL20chemokine (C-C motif) ligand 200.024
CCR3chemokine (C-C motif) receptor 30.024
CXCR3chemokine (C-X-C motif) receptor 30.023
PUM1pumilio homolog 1 (Drosophila)0.023
IL16interleukin 16 (lymphocyte chemoattractant factor)0.022
CBX4chromobox homolog 40.022
IDEinsulin-degrading enzyme0.020
CXCL11chemokine (C-X-C motif) ligand 110.020
KLHL24kelch-like 24 (Drosophila)0.019
CAPRIN2caprin family member 20.019
IL2RGinterleukin 2 receptor, gamma0.019
MMP12matrix metallopeptidase 12 (macrophage elastase)0.019
FCER2Fc fragment of IgE, low affinity II, receptor for (CD23)0.018
SC4MOLsterol-C4-methyl oxidase-like0.018
TNFRSF9tumor necrosis factor receptor superfamily, member 90.017
FHL3four and a half LIM domains 30.017
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.017
NRP1neuropilin 10.016
INSIG1insulin induced gene 10.016
CCR8chemokine (C-C motif) receptor 80.015
CD83CD83 molecule0.015
IL21Rinterleukin 21 receptor0.015
THBS1thrombospondin 10.015
IL10interleukin 100.015
EBI3Epstein-Barr virus induced 30.014
KLRD1killer cell lectin-like receptor subfamily D, member 10.014
AKT2v-akt murine thymoma viral oncogene homolog 20.014
SPIN1spindlin 10.014
SOX7SRY (sex determining region Y)-box 70.014
ACVR2Bactivin A receptor, type IIB0.014
CCR6chemokine (C-C motif) receptor 60.013
CD160CD160 molecule0.013
DPP4dipeptidyl-peptidase 40.013
CCR1chemokine (C-C motif) receptor 10.013
CD74CD74 molecule, major histocompatibility complex, class II invariant chain0.012
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Smad4MAD homolog 4 (Drosophila)1.000
Bmpr1abone morphogenetic protein receptor, type 1A0.999
Apcadenomatosis polyposis coli0.998
Tgfbr2transforming growth factor, beta receptor II0.994
Ptch1patched homolog 10.958
Smad3MAD homolog 3 (Drosophila)0.927
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.919
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.865
Ece1endothelin converting enzyme 10.807
Sox9SRY-box containing gene 90.722
Acvr1activin A receptor, type 10.701
Tgfbr1transforming growth factor, beta receptor I0.689
Ctnnb1catenin (cadherin associated protein), beta 10.680
Foxc1forkhead box C10.662
Amhr2anti-Mullerian hormone type 2 receptor0.660
Tgfb2transforming growth factor, beta 20.609
Bmi1Bmi1 polycomb ring finger oncogene0.584
Csf1colony stimulating factor 1 (macrophage)0.573
Meox2mesenchyme homeobox 20.565
Ednraendothelin receptor type A0.525
Hoxa3homeobox A30.513
Fgfr1fibroblast growth factor receptor 10.442
Smad1MAD homolog 1 (Drosophila)0.426
Ccr2chemokine (C-C motif) receptor 20.423
Fgfr3fibroblast growth factor receptor 30.414
Bmp4bone morphogenetic protein 40.407
Atxn1ataxin 10.402
Prrx1paired related homeobox 10.374
Ccr1chemokine (C-C motif) receptor 10.366
Ptenphosphatase and tensin homolog0.346
Prkg1protein kinase, cGMP-dependent, type I0.339
Mapkapk2MAP kinase-activated protein kinase 20.336
Cd44CD44 antigen0.335
Tefthyrotroph embryonic factor0.318
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.308
Bptfbromodomain PHD finger transcription factor0.292
Nos3nitric oxide synthase 3, endothelial cell0.287
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.287
Fgf8fibroblast growth factor 80.277
Rnf2ring finger protein 20.261
Inhbbinhibin beta-B0.259
Bmp7bone morphogenetic protein 70.245
Fgfr2fibroblast growth factor receptor 20.227
Efemp2epidermal growth factor-containing fibulin-like extracellular matrix protein 20.222
Bmp2bone morphogenetic protein 20.221
Rargretinoic acid receptor, gamma0.219
Acvr1bactivin A receptor, type 1B0.214
Rararetinoic acid receptor, alpha0.211
Vegfavascular endothelial growth factor A0.211
Foxc2forkhead box C20.208
Ccl2chemokine (C-C motif) ligand 20.199
Acvr2aactivin receptor IIA0.173
BrafBraf transforming gene0.170
Ldlrlow density lipoprotein receptor0.157
Kiss1rKISS1 receptor0.157
Nf1neurofibromatosis 10.147
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.137
Atp7aATPase, Cu++ transporting, alpha polypeptide0.132
Pcgf2polycomb group ring finger 20.130
Mkl2MKL/myocardin-like 20.128
Cdh5cadherin 50.126
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.123
Smosmoothened homolog (Drosophila)0.121
Dkc1dyskeratosis congenita 1, dyskerin homolog (human)0.121
Shhsonic hedgehog0.120
Ifnginterferon gamma0.120
Gli2GLI-Kruppel family member GLI20.118
Shc1src homology 2 domain-containing transforming protein C10.106
Tlr2toll-like receptor 20.099
Gja1gap junction protein, alpha 10.094
Pknox1Pbx/knotted 1 homeobox0.090
Fshrfollicle stimulating hormone receptor0.090
Agtr1aangiotensin II receptor, type 1a0.080
Smad5MAD homolog 5 (Drosophila)0.079
Baz1abromodomain adjacent to zinc finger domain 1A0.079
Inhbainhibin beta-A0.078
Npr2natriuretic peptide receptor 20.076
Mks1Meckel syndrome, type 10.073
Fbn1fibrillin 10.072
Ehmt1euchromatic histone methyltransferase 10.071
Pdgfbplatelet derived growth factor, B polypeptide0.069
MgaMAX gene associated0.069
Scmh1sex comb on midleg homolog 10.068
Inhainhibin alpha0.067
Rc3h1RING CCCH (C3H) domains 10.065
Gsk3bglycogen synthase kinase 3 beta0.063
Cxcr4chemokine (C-X-C motif) receptor 40.061
Mvdmevalonate (diphospho) decarboxylase0.061
Arid1aAT rich interactive domain 1A (SWI-like)0.061
Acvr2bactivin receptor IIB0.059
Rbl2retinoblastoma-like 20.058
Kitlkit ligand0.058
Esr1estrogen receptor 1 (alpha)0.058
Twsg1twisted gastrulation homolog 1 (Drosophila)0.058
Chukconserved helix-loop-helix ubiquitous kinase0.057
BmperBMP-binding endothelial regulator0.057
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism