The network for 'potassium ion homeostasis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

potassium ion homeostasis

Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell.

NameDescriptionProbabilityFunc Analog Organism
Drd1adopamine receptor D1A0.094
Mapk3mitogen activated protein kinase 30.081
Ank2ankyrin 2, neuronal0.070
Atp1b2ATPase, Na+/K+ transporting, beta 2 polypeptide0.056
Arpp21cAMP-regulated phosphoprotein 210.047
Atp1b1ATPase, Na+/K+ transporting, beta 1 polypeptide0.035
Chpcalcium binding protein p220.033
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform0.032
Hcn1hyperpolarization-activated cyclic nucleotide-gated potassium channel 10.028
Gabrb1gamma-aminobutyric acid (GABA) A receptor, beta 10.028
Hs3st2heparan sulfate (glucosamine) 3-O-sulfotransferase 20.026
Kcnd3potassium voltage-gated channel, Shal-related subfamily, member 30.026
Crhbpcorticotropin releasing hormone binding protein0.025
Opcmlopioid binding protein/cell adhesion molecule-like0.024
Dlgap1discs, large (Drosophila) homolog-associated protein 10.024
Slc12a1solute carrier family 12 (sodium/potassium/chloride transporters), member 10.023
Nrxn3neurexin 30.023
Cntn3contactin 3 (plasmacytoma associated)0.023
Kcnk3potassium channel, subfamily K, member 30.022
Glra3glycine receptor, alpha 30.021
Mas1MAS1 oncogene0.020
Coro2bcoronin, actin binding protein, 2B0.020
Myt1lmyelin transcription factor 1-like0.019
Cyp2b21cytochrome P450, family 2, subfamily b, polypeptide 210.019
Vipvasoactive intestinal peptide0.019
Cacna1ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.017
Psbpc2prostatic steroid-binding protein C20.017
Scn4bsodium channel, voltage-gated, type IV, beta0.017
Rph3arabphilin 3A0.017
Brunol4bruno-like 4, RNA binding protein (Drosophila)0.017
Dgkbdiacylglycerol kinase, beta0.016
Fgf14fibroblast growth factor 140.016
Map1amicrotubule-associated protein 1A0.016
Gnao1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O0.016
Chrm1cholinergic receptor, muscarinic 10.016
Rimbp2RIMS binding protein 20.015
Chst10carbohydrate sulfotransferase 100.015
Cscitrate synthase0.015
Epha5EphA50.015
Dbc1deleted in bladder cancer 1 (human)0.015
Tmem90btransmembrane protein 90B0.015
Gabra1gamma-aminobutyric acid (GABA) A receptor, alpha 10.015
Crhcorticotropin releasing hormone0.015
Arhgef9Cdc42 guanine nucleotide exchange factor (GEF) 90.014
Gpr61G protein-coupled receptor 610.014
Kcna4potassium voltage-gated channel, shaker-related subfamily, member 40.014
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.014
Sorcs3sortilin-related VPS10 domain containing receptor 30.014
Slc38a1solute carrier family 38, member 10.014
RGD1310269hypothetical LOC3144720.014
Snap91synaptosomal-associated protein 910.014
Necab1N-terminal EF-hand calcium binding protein 10.014
Faim2Fas apoptotic inhibitory molecule 20.014
Elavl4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)0.014
Ddndendrin0.014
Mfrpmembrane frizzled-related protein0.014
S100bS100 calcium binding protein B0.013
Tnmdtenomodulin0.013
CadpsCa++-dependent secretion activator0.013
Cplx1complexin 10.013
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.013
Cited1Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 10.013
Fgf13fibroblast growth factor 130.013
Slc28a3solute carrier family 28 (sodium-coupled nucleoside transporter), member 30.013
Nrn1neuritin 10.013
LOC685244similar to IQ motif and Sec7 domain 20.013
Rims1regulating synaptic membrane exocytosis 10.013
Gria1glutamate receptor, ionotropic, AMPA 10.013
Kcnj3potassium inwardly-rectifying channel, subfamily J, member 30.013
Grm4glutamate receptor, metabotropic 40.013
Acsl6acyl-CoA synthetase long-chain family member 60.012
Tmod2tropomodulin 20.012
Ryr2ryanodine receptor 2, cardiac0.012
Galntl1UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 10.012
Gria4glutamate receptor, ionotrophic, AMPA 40.012
Atp2a2ATPase, Ca++ transporting, cardiac muscle, slow twitch 20.012
RGD1560559similar to RIKEN cDNA 2310042E220.012
Nxph1neurexophilin 10.012
Rab1bRAB1B, member RAS oncogene family0.012
Kcnh1potassium voltage-gated channel, subfamily H (eag-related), member 10.012
Cntnap1contactin associated protein 10.012
Svs5seminal vesicle secretory protein 50.012
Rhorhodopsin0.012
Camk2bcalcium/calmodulin-dependent protein kinase II beta0.012
Ifnginterferon gamma0.012
Epb41l1erythrocyte membrane protein band 4.1-like 10.012
Syt6synaptotagmin VI0.011
Adrb1adrenergic, beta-1-, receptor0.011
Sparcl1SPARC-like 1 (hevin)0.011
Slc24a3solute carrier family 24 (sodium/potassium/calcium exchanger), member 30.011
Aardalanine and arginine rich domain containing protein0.011
Prl7d1prolactin family 7, subfamily d, member 10.011
Cyp11b1cytochrome P450, family 11, subfamily b, polypeptide 10.011
Cpne9copine family member IX0.011
Nfascneurofascin0.011
Kcnip2Kv channel-interacting protein 20.011
Sema4fsema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F0.011
Begainbrain-enriched guanylate kinase-associated0.011
Olr416olfactory receptor 4160.011
Syt4synaptotagmin IV0.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ACTN2actinin, alpha 20.993
MYOZ1myozenin 10.549
KCNB1potassium voltage-gated channel, Shab-related subfamily, member 10.042
DDAH2dimethylarginine dimethylaminohydrolase 20.037
NDRG2NDRG family member 20.022
TTNtitin0.021
KCNA4potassium voltage-gated channel, shaker-related subfamily, member 40.019
NPYneuropeptide Y0.018
ATP4BATPase, H+/K+ exchanging, beta polypeptide0.011
HIPK4homeodomain interacting protein kinase 40.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.981
Atp2b2ATPase, Ca++ transporting, plasma membrane 20.979
Ank1ankyrin 1, erythroid0.898
Kcna1potassium voltage-gated channel, shaker-related subfamily, member 10.757
Slc12a1solute carrier family 12, member 10.692
Esrrbestrogen related receptor, beta0.637
Kcnq1potassium voltage-gated channel, subfamily Q, member 10.597
Cacna1dcalcium channel, voltage-dependent, L type, alpha 1D subunit0.542
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.499
Hand2heart and neural crest derivatives expressed transcript 20.481
Kcne1potassium voltage-gated channel, Isk-related subfamily, member 10.447
Grid2glutamate receptor, ionotropic, delta 20.386
Pax6paired box gene 60.341
Cdh23cadherin 23 (otocadherin)0.323
Srrm4serine/arginine repetitive matrix 40.321
Tmc1transmembrane channel-like gene family 10.302
Cckbrcholecystokinin B receptor0.301
Calb1calbindin 10.267
Grxcr1glutaredoxin, cysteine rich 10.240
Cacna1ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.223
Lrp2low density lipoprotein receptor-related protein 20.207
Vamp2vesicle-associated membrane protein 20.190
Kcna2potassium voltage-gated channel, shaker-related subfamily, member 20.184
Dab1disabled homolog 1 (Drosophila)0.172
Frmd5FERM domain containing 50.163
Chrna9cholinergic receptor, nicotinic, alpha polypeptide 90.162
Ostaorganic solute transporter alpha0.153
Inainternexin neuronal intermediate filament protein, alpha0.153
Slc22a12solute carrier family 22 (organic anion/cation transporter), member 120.152
Phkg1phosphorylase kinase gamma 10.144
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.144
Six3sine oculis-related homeobox 3 homolog (Drosophila)0.143
Kcnk3potassium channel, subfamily K, member 30.142
Wnk2WNK lysine deficient protein kinase 20.140
Clstn1calsyntenin 10.139
Cntn2contactin 20.137
Nos1nitric oxide synthase 1, neuronal0.136
InadlInaD-like (Drosophila)0.132
Abcc9ATP-binding cassette, sub-family C (CFTR/MRP), member 90.131
Fgf8fibroblast growth factor 80.118
DaoD-amino acid oxidase0.116
Hrchistidine rich calcium binding protein0.109
Kcnj3potassium inwardly-rectifying channel, subfamily J, member 30.107
Myl7myosin, light polypeptide 7, regulatory0.104
Syt7synaptotagmin VII0.104
Gcm2glial cells missing homolog 2 (Drosophila)0.103
Pcsk4proprotein convertase subtilisin/kexin type 40.102
Msx1homeobox, msh-like 10.102
Gria4glutamate receptor, ionotropic, AMPA4 (alpha 4)0.097
Atp1a2ATPase, Na+/K+ transporting, alpha 2 polypeptide0.097
Homer1homer homolog 1 (Drosophila)0.094
Pla2g5phospholipase A2, group V0.093
Grik2glutamate receptor, ionotropic, kainate 2 (beta 2)0.093
UncxUNC homeobox0.092
Hsd3b4hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 40.092
Pax3paired box gene 30.090
Nrip3nuclear receptor interacting protein 30.090
Mpp3membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)0.089
Foxi3forkhead box I30.088
Drd2dopamine receptor D20.088
Umoduromodulin0.087
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.087
Clcnkachloride channel Ka0.087
Kcnj11potassium inwardly rectifying channel, subfamily J, member 110.086
Gjb6gap junction protein, beta 60.085
Neurod2neurogenic differentiation 20.084
Pou3f4POU domain, class 3, transcription factor 40.084
Kcnab3potassium voltage-gated channel, shaker-related subfamily, beta member 30.081
Maptmicrotubule-associated protein tau0.080
Atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.078
Slc23a3solute carrier family 23 (nucleobase transporters), member 30.077
Rtn2reticulon 2 (Z-band associated protein)0.076
Abca4ATP-binding cassette, sub-family A (ABC1), member 40.076
Irx4Iroquois related homeobox 4 (Drosophila)0.075
Slc6a1solute carrier family 6 (neurotransmitter transporter, GABA), member 10.074
Slc5a11solute carrier family 5 (sodium/glucose cotransporter), member 110.074
GsbsG substrate0.074
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.073
Kcnj12potassium inwardly-rectifying channel, subfamily J, member 120.072
Slc22a6solute carrier family 22 (organic anion transporter), member 60.071
Hoxb4homeobox B40.070
Bsnbassoon0.070
Abcc8ATP-binding cassette, sub-family C (CFTR/MRP), member 80.070
Hand1heart and neural crest derivatives expressed transcript 10.070
Cntnap1contactin associated protein-like 10.070
Phexphosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)0.070
Pou4f3POU domain, class 4, transcription factor 30.068
Mfsd4major facilitator superfamily domain containing 40.067
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.067
Foxc1forkhead box C10.067
Odz2odd Oz/ten-m homolog 2 (Drosophila)0.065
Slc5a1solute carrier family 5 (sodium/glucose cotransporter), member 10.064
Cacnb2calcium channel, voltage-dependent, beta 2 subunit0.063
Kcnd2potassium voltage-gated channel, Shal-related family, member 20.063
Hs6st3heparan sulfate 6-O-sulfotransferase 30.063
Pde1cphosphodiesterase 1C0.063
Nkx6-3NK6 homeobox 30.062
Fgf12fibroblast growth factor 120.062
Tcfap2btranscription factor AP-2 beta0.059
Sox15SRY-box containing gene 150.058
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
TRK1Trk1p0.837
NHA1Nha1p0.571
TRK2Trk2p0.398
MIG2Mig2p0.299
FPS1Fps1p0.153
TOK1Tok1p0.149
ROX1Rox1p0.113
YKR075Chypothetical protein0.107
YPL014Whypothetical protein0.095
GAT2Gat2p0.085
NRG1Nrg1p0.072
YKL187Chypothetical protein0.066
MIG3Mig3p0.057
VPS8Vps8p0.055
HAL5Hal5p0.049
GIS4Gis4p0.049
TRA1Tra1p0.048
YBR235Whypothetical protein0.047
VID24Vid24p0.045
MIG1Mig1p0.040
MRM1Mrm1p0.036
YML081Whypothetical protein0.036
RGS2Rgs2p0.035
RSC9Rsc9p0.032
SWI1Swi1p0.032
HSF1Hsf1p0.032
HXT3Hxt3p0.030
YPR157Whypothetical protein0.028
MDM38Mdm38p0.025
CAB4Cab4p0.024
SOK2Sok2p0.023
TYE7Tye7p0.023
HAL9Hal9p0.021
CSR2Csr2p0.020
LYS5Lys5p0.020
CAT8Cat8p0.018
YER064Chypothetical protein0.018
TOR2Tor2p0.017
TOS8Tos8p0.017
AQR1Aqr1p0.017
AGP2Agp2p0.016
IRC8Irc8p0.015
MRP4Mrp4p0.015
RDS2Rds2p0.015
YIR035Chypothetical protein0.015
SNF3Snf3p0.015
PHM8Phm8p0.014
MOB1Mob1p0.014
YNL234Whypothetical protein0.013
YLR264C-Ahypothetical protein0.013
SRD1Srd1p0.013
ATF1Atf1p0.013
SMP1Smp1p0.012
TBS1Tbs1p0.012
ICY1Icy1p0.012
POG1Pog1p0.012
HOR2Hor2p0.012
PMD1Pmd1p0.012
SKS1Sks1p0.012
PCL2Pcl2p0.012
FIR1Fir1p0.012
FMP48Fmp48p0.012
HST3Hst3p0.011
LEU2Leu2p0.011
BSC2Bsc2p0.011
CHA1Cha1p0.011
MGA2Mga2p0.011
RLM1Rlm1p0.011
CUP1-1Cup1-1p0.011
DAL81Dal81p0.011
FPK1Fpk1p0.011
MDM32Mdm32p0.011
MER1Mer1p0.010
GCN2Gcn2p0.010
PUT1Put1p0.010