The network for 'alkaloid metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

alkaloid metabolic process

The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases).

NameDescriptionProbabilityFunc Analog Organism
Cyp2a1cytochrome P450, family 2, subfamily a, polypeptide 10.994
Cyp2b1cytochrome P450, family 2, subfamily b, polypeptide 10.986
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.964
Cyp3a23/3a1cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 10.915
Abcc6ATP-binding cassette, subfamily C (CFTR/MRP), member 60.909
Sult1c3sulfotransferase family, cytosolic, 1C, member 30.844
Ugt2b1UDP glucuronosyltransferase 2 family, polypeptide B10.803
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.794
LOC293989cytochrome P450-like0.762
Cyp2d3cytochrome P450, family 2, subfamily d, polypeptide 30.743
Cyp3a18cytochrome P450, family 3, subfamily a, polypeptide 180.741
Cyp4a10cytochrome P450, family 4, subfamily a, polypeptide 100.656
Cyp2c23cytochrome P450, family 2, subfamily c, polypeptide 230.634
Sult1c2sulfotransferase family, cytosolic, 1C, member 20.608
Cyp2d2cytochrome P450, family 2, subfamily d, polypeptide 20.587
Sult1b1sulfotransferase family, cytosolic, 1B, member 10.576
Sult1e1sulfotransferase family 1E, estrogen-preferring, member 10.554
Ugt2b5UDP glucuronosyltransferase 2 family, polypeptide B50.512
Cyp1a1cytochrome P450, family 1, subfamily a, polypeptide 10.478
Mettl7bmethyltransferase like 7B0.454
Otcornithine carbamoyltransferase0.405
Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 20.379
Dpysdihydropyrimidinase0.378
LOC100365112carboxylesterase-like0.367
Akr1c18aldo-keto reductase family 1, member C180.364
A1i3alpha-1-inhibitor III0.357
Cyp4a8cytochrome P450, family 4, subfamily a, polypeptide 80.345
Cyp2d4cytochrome P450, family 2, subfamily d, polypeptide 40.342
Gnmtglycine N-methyltransferase0.334
LOC494499LOC494499 protein0.331
Pon1paraoxonase 10.331
Apobapolipoprotein B0.327
Gsta2glutathione S-transferase A20.323
Cyp2b2cytochrome P450, family 2, subfamily b, polypeptide 20.310
Cyp2c13cytochrome P450, family 2, subfamily c, polypeptide 130.283
Ugt2b37UDP-glucuronosyltransferase 2 family, member 370.281
Crygfcrystallin, gamma F0.265
Cyp3a2cytochrome P450, family 3, subfamily a, polypeptide 20.256
Rxrgretinoid X receptor gamma0.253
Azgp1alpha-2-glycoprotein 1, zinc-binding0.222
Cyp2a2cytochrome P450, family 2, subfamily a, polypeptide 20.217
Cyp2b3cytochrome P450, family 2, subfamily b, polypeptide 30.214
Cyp2c11cytochrome P450, subfamily 2, polypeptide 110.175
Haao3-hydroxyanthranilate 3,4-dioxygenase0.168
Gsta5glutathione S-transferase Yc2 subunit0.165
Cyp2f4cytochrome P450, family 2, subfamily f, polypeptide 40.156
Serpina1serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10.154
Slco1a4solute carrier organic anion transporter family, member 1a40.149
Tdo2tryptophan 2,3-dioxygenase0.142
Cyp4a2cytochrome P450, family 4, subfamily a, polypeptide 20.139
Slco1a1solute carrier organic anion transporter family, member 1a10.137
Cyp4f1cytochrome P450, family 4, subfamily f, polypeptide 10.133
Olr1701olfactory receptor 17010.128
Slc6a4solute carrier family 6 (neurotransmitter transporter, serotonin), member 40.127
Cyp2c22cytochrome P450, family 2, subfamily c, polypeptide 220.120
LOC100361864UDP-glucuronosyltransferase 2B3-like0.120
Pigrpolymeric immunoglobulin receptor0.117
Nr0b2nuclear receptor subfamily 0, group B, member 20.104
Gckrglucokinase (hexokinase 4) regulator0.104
Abcb11ATP-binding cassette, subfamily B (MDR/TAP), member 110.103
Ces1ecarboxylesterase 1E0.099
Fabp1fatty acid binding protein 1, liver0.098
Hsd17b6hydroxysteroid (17-beta) dehydrogenase 60.093
Cyp7a1cytochrome P450, family 7, subfamily a, polypeptide 10.091
Klkb1kallikrein B, plasma 10.091
Slc27a2solute carrier family 27 (fatty acid transporter), member 20.085
Kmokynurenine 3-monooxygenase (kynurenine 3-hydroxylase)0.075
LOC100361547Cytochrome P450, family 2, subfamily c, polypeptide 7-like0.074
Cyp2b21cytochrome P450, family 2, subfamily b, polypeptide 210.071
Hpd4-hydroxyphenylpyruvate dioxygenase0.067
Cyp2b15cytochrome P450, family 2, subfamily b, polypeptide 150.065
Dhfrdihydrofolate reductase0.065
Acaa1bacetyl-Coenzyme A acyltransferase 1B0.064
Ugt2b36UDP glucuronosyltransferase 2 family, polypeptide B360.063
LOC246267resection-induced TPI (rs11)0.060
Inmtindolethylamine N-methyltransferase0.056
Ces1fcarboxylesterase 1F0.054
Apoa2apolipoprotein A-II0.052
F9coagulation factor IX0.052
Cyp4f4cytochrome P450, family 4, subfamily f, polypeptide 40.052
Sstr4somatostatin receptor 40.050
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.050
Aqp9aquaporin 90.048
Rgnregucalcin (senescence marker protein-30)0.047
Fdxrferredoxin reductase0.046
Cyp2c12cytochrome P450, family 2, subfamily c, polypeptide 120.045
Pck1phosphoenolpyruvate carboxykinase 1 (soluble)0.045
Baatbile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)0.044
Ugt2a1UDP glucuronosyltransferase 2 family, polypeptide A10.042
Slco1b3solute carrier organic anion transporter family, member 1b30.042
LOC299282Serine protease inhibitor0.042
Acot12acyl-CoA thioesterase 120.041
Colqcollagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase0.041
Foxa1forkhead box A10.041
Abcc2ATP-binding cassette, subfamily C (CFTR/MRP), member 20.039
Mosc1MOCO sulphurase C-terminal domain containing 10.038
Cybrd1cytochrome b reductase 10.038
Akr7a3aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)0.038
Ces1ccarboxylesterase 1C0.038
Fgfr4fibroblast growth factor receptor 40.037
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CYP2C9cytochrome P450, family 2, subfamily C, polypeptide 91.000
CYP2A6cytochrome P450, family 2, subfamily A, polypeptide 61.000
CYP4A11cytochrome P450, family 4, subfamily A, polypeptide 110.982
CYP3A7cytochrome P450, family 3, subfamily A, polypeptide 70.976
CYP3A43cytochrome P450, family 3, subfamily A, polypeptide 430.963
CYP2B6cytochrome P450, family 2, subfamily B, polypeptide 60.899
CYP3A5cytochrome P450, family 3, subfamily A, polypeptide 50.864
CYP3A4cytochrome P450, family 3, subfamily A, polypeptide 40.804
CYP2C19cytochrome P450, family 2, subfamily C, polypeptide 190.609
C8Bcomplement component 8, beta polypeptide0.584
CYP4F12cytochrome P450, family 4, subfamily F, polypeptide 120.452
CYP4F2cytochrome P450, family 4, subfamily F, polypeptide 20.444
C8Acomplement component 8, alpha polypeptide0.432
C6complement component 60.415
HRGhistidine-rich glycoprotein0.408
ADH6alcohol dehydrogenase 6 (class V)0.390
MASP2mannan-binding lectin serine peptidase 20.341
F9coagulation factor IX0.248
CYP1A2cytochrome P450, family 1, subfamily A, polypeptide 20.225
CYP2C18cytochrome P450, family 2, subfamily C, polypeptide 180.217
MAT1Amethionine adenosyltransferase I, alpha0.216
GLYATglycine-N-acyltransferase0.216
DAOD-amino-acid oxidase0.212
ALDOBaldolase B, fructose-bisphosphate0.203
OTCornithine carbamoyltransferase0.163
FMO4flavin containing monooxygenase 40.153
NAT2N-acetyltransferase 2 (arylamine N-acetyltransferase)0.142
CFHR4complement factor H-related 40.136
SULT1B1sulfotransferase family, cytosolic, 1B, member 10.129
APCSamyloid P component, serum0.125
SERPINC1serpin peptidase inhibitor, clade C (antithrombin), member 10.122
SLC10A1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.104
NR1I2nuclear receptor subfamily 1, group I, member 20.103
SULT2A1sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 10.103
LAMC3laminin, gamma 30.100
PON1paraoxonase 10.100
GBA3glucosidase, beta, acid 3 (cytosolic)0.089
GSTA3glutathione S-transferase alpha 30.077
ABCC2ATP-binding cassette, sub-family C (CFTR/MRP), member 20.075
UGT2B15UDP glucuronosyltransferase 2 family, polypeptide B150.075
ITIH4inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)0.073
HMGCS23-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)0.073
PLGplasminogen0.072
FETUBfetuin B0.072
G6PCglucose-6-phosphatase, catalytic subunit0.069
SLC2A2solute carrier family 2 (facilitated glucose transporter), member 20.068
CCL16chemokine (C-C motif) ligand 160.067
NR1H4nuclear receptor subfamily 1, group H, member 40.061
HABP2hyaluronan binding protein 20.059
C4BPBcomplement component 4 binding protein, beta0.058
AGXT2alanine--glyoxylate aminotransferase 20.057
CYP4F3cytochrome P450, family 4, subfamily F, polypeptide 30.056
CRPC-reactive protein, pentraxin-related0.055
F11coagulation factor XI0.055
GPLD1glycosylphosphatidylinositol specific phospholipase D10.051
AADACarylacetamide deacetylase (esterase)0.050
DPYSdihydropyrimidinase0.050
LGALS4lectin, galactoside-binding, soluble, 40.050
PFKFB16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 10.048
ABCB11ATP-binding cassette, sub-family B (MDR/TAP), member 110.048
C4BPAcomplement component 4 binding protein, alpha0.048
F13Bcoagulation factor XIII, B polypeptide0.047
BHMTbetaine--homocysteine S-methyltransferase0.047
MTTPmicrosomal triglyceride transfer protein0.047
SLC22A1solute carrier family 22 (organic cation transporter), member 10.047
XDHxanthine dehydrogenase0.046
APOC3apolipoprotein C-III0.046
HALhistidine ammonia-lyase0.046
C9complement component 90.045
A2Malpha-2-macroglobulin0.042
MEP1Bmeprin A, beta0.042
APOC4apolipoprotein C-IV0.041
CYP4F11cytochrome P450, family 4, subfamily F, polypeptide 110.040
PAHphenylalanine hydroxylase0.040
KNG1kininogen 10.039
ANXA10annexin A100.039
HPXhemopexin0.039
DNASE1L3deoxyribonuclease I-like 30.037
LECT2leukocyte cell-derived chemotaxin 20.036
A1CFAPOBEC1 complementation factor0.036
PCK1phosphoenolpyruvate carboxykinase 1 (soluble)0.036
GYS2glycogen synthase 2 (liver)0.035
CYP7A1cytochrome P450, family 7, subfamily A, polypeptide 10.034
CYP2A7cytochrome P450, family 2, subfamily A, polypeptide 70.034
LPAlipoprotein, Lp(a)0.034
CYP1A1cytochrome P450, family 1, subfamily A, polypeptide 10.033
HPD4-hydroxyphenylpyruvate dioxygenase0.032
PGRMC1progesterone receptor membrane component 10.032
PIK3C2Gphosphoinositide-3-kinase, class 2, gamma polypeptide0.032
TM4SF4transmembrane 4 L six family member 40.030
CNGA1cyclic nucleotide gated channel alpha 10.029
HGDhomogentisate 1,2-dioxygenase0.029
CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 10.029
FUT6fucosyltransferase 6 (alpha (1,3) fucosyltransferase)0.028
GATMglycine amidinotransferase (L-arginine:glycine amidinotransferase)0.028
AKR1C4aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)0.028
ACRV1acrosomal vesicle protein 10.028
ENTPD5ectonucleoside triphosphate diphosphohydrolase 50.028
TM4SF5transmembrane 4 L six family member 50.028
UGT2B17UDP glucuronosyltransferase 2 family, polypeptide B170.028
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism