The network for 'behavior' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms


The internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.

NameDescriptionProbabilityFunc Analog Organism
Reg3gregenerating islet-derived 3 gamma0.847
Sstr1somatostatin receptor 10.793
Dlg4discs, large homolog 4 (Drosophila)0.790
Chrna7cholinergic receptor, nicotinic, alpha 70.766
Ptafrplatelet-activating factor receptor0.761
Dlgap3discs, large (Drosophila) homolog-associated protein 30.743
Syt4synaptotagmin IV0.698
Dlgap1discs, large (Drosophila) homolog-associated protein 10.697
Cxcl2chemokine (C-X-C motif) ligand 20.695
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.690
Calcrlcalcitonin receptor-like0.686
Cckbrcholecystokinin B receptor0.678
Grin2aglutamate receptor, ionotropic, N-methyl D-aspartate 2A0.677
Jak2Janus kinase 20.674
Nrxn3neurexin 30.655
Elavl4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)0.651
Gnao1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O0.647
Slc6a11solute carrier family 6 (neurotransmitter transporter, GABA), member 110.642
Chrngcholinergic receptor, nicotinic, gamma0.612
Tacr2tachykinin receptor 20.601
Adrb1adrenergic, beta-1-, receptor0.601
Hcn1hyperpolarization-activated cyclic nucleotide-gated potassium channel 10.577
Prlhrprolactin releasing hormone receptor0.570
Slc18a2solute carrier family 18 (vesicular monoamine), member 20.565
Ctnnd2catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)0.552
Pmfbp1polyamine modulated factor 1 binding protein 10.541
Tnftumor necrosis factor (TNF superfamily, member 2)0.526
Casp3caspase 30.521
Atp2a3ATPase, Ca++ transporting, ubiquitous0.501
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.499
Rxrgretinoid X receptor gamma0.485
Cacna1ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.480
Accn2amiloride-sensitive cation channel 2, neuronal0.480
Nr4a3nuclear receptor subfamily 4, group A, member 30.477
Prkcgprotein kinase C, gamma0.468
Atxn1ataxin 10.467
Kcnj11potassium inwardly rectifying channel, subfamily J, member 110.466
Itgb7integrin, beta 70.457
Nr1h4nuclear receptor subfamily 1, group H, member 40.457
Slc6a7solute carrier family 6 (neurotransmitter transporter, L-proline), member 70.454
Gja1gap junction protein, alpha 10.454
Gria1glutamate receptor, ionotropic, AMPA 10.451
Kcnab1potassium voltage-gated channel, shaker-related subfamily, beta member 10.448
Nrxn1neurexin 10.447
Kcnq3potassium voltage-gated channel, KQT-like subfamily, member 30.438
Gja6gap junction protein, alpha 60.436
Kcnj8potassium inwardly-rectifying channel, subfamily J, member 80.433
Trhr2thyrotropin releasing hormone receptor 20.433
Slc18a3solute carrier family 18 (vesicular acetylcholine), member 30.433
Egr2early growth response 20.432
Metmet proto-oncogene0.431
Cdh6cadherin 60.431
Grin1glutamate receptor, ionotropic, N-methyl D-aspartate 10.431
Crhr1corticotropin releasing hormone receptor 10.430
Egr4early growth response 40.429
Magmyelin-associated glycoprotein0.428
Vipvasoactive intestinal peptide0.422
Foxs1forkhead box S10.417
Cacnb1calcium channel, voltage-dependent, beta 1 subunit0.417
Olr1082olfactory receptor 10820.414
Ahraryl hydrocarbon receptor0.412
Mmp10matrix metallopeptidase 100.409
Ptgs2prostaglandin-endoperoxide synthase 20.409
Clockclock homolog (mouse)0.408
Nr4a2nuclear receptor subfamily 4, group A, member 20.408
Adap1ArfGAP with dual PH domains 10.408
Lphn2latrophilin 20.407
Fgf14fibroblast growth factor 140.406
Gucy2fguanylate cyclase 2F0.404
Camk2acalcium/calmodulin-dependent protein kinase II alpha0.399
Accn3amiloride-sensitive cation channel 30.395
Il12binterleukin 12B0.395
Ntrk3neurotrophic tyrosine kinase, receptor, type 30.394
Shank1SH3 and multiple ankyrin repeat domains 10.393
Mobpmyelin-associated oligodendrocyte basic protein0.390
Atp6v1g3ATPase, H+ transporting, lysosomal V1 subunit G30.382
Grk1G protein-coupled receptor kinase 10.381
Hes2hairy and enhancer of split 2 (Drosophila)0.378
Mef2dmyocyte enhancer factor 2D0.377
Crhbpcorticotropin releasing hormone binding protein0.370
Myo1bmyosin Ib0.366
Foxd3forkhead box D30.360
VgfVGF nerve growth factor inducible0.359
Homer1homer homolog 1 (Drosophila)0.358
Myt1lmyelin transcription factor 1-like0.356
Gria2glutamate receptor, ionotropic, AMPA 20.350
FosFBJ osteosarcoma oncogene0.347
Pak2p21 protein (Cdc42/Rac)-activated kinase 20.344
Htr1d5-hydroxytryptamine (serotonin) receptor 1D0.341
Cmklr1chemokine-like receptor 10.335
Vdrvitamin D (1,25- dihydroxyvitamin D3) receptor0.333
Exoc5exocyst complex component 50.332
Grik1glutamate receptor, ionotropic, kainate 10.330
Rgs9regulator of G-protein signaling 90.329
Mpp2membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)0.329
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
unc-9Protein UNC-90.984
vab-3Protein VAB-30.865
egl-18Protein EGL-180.856
unc-54Protein UNC-540.846
egl-46Protein EGL-460.842
egl-13Protein EGL-130.839
cam-1Protein CAM-10.832
pha-4Protein PHA-40.807
unc-53Protein UNC-530.765
egl-30Protein EGL-300.764
lec-1Protein LEC-10.759
ceh-20Protein CEH-200.689
lin-29Protein LIN-290.660
unc-73Protein UNC-730.592
lem-3Protein LEM-30.589
hlh-2Protein HLH-20.588
pry-1Protein PRY-10.574
sdz-28Protein SDZ-280.564
lsy-2Protein LSY-20.563
egl-15Protein EGL-150.561
unc-86Protein UNC-860.550
rig-6Protein RIG-60.545
egl-36Protein EGL-360.527
ida-1Protein IDA-10.503
daf-11Protein DAF-110.496
ldb-1Protein LDB-10.494
haf-9Protein HAF-90.484
nphp-4Protein NPHP-40.477
unc-6Protein UNC-60.473
pdfr-1Protein PDFR-10.468
eps-8Protein EPS-80.459
unc-62Protein UNC-620.448
zip-7Protein ZIP-70.447
itx-1Protein ITX-10.446
ceh-16Protein CEH-160.434
F40F4.7Protein F40F4.70.431
hbl-1Protein HBL-10.431
syg-1Protein SYG-10.427
egl-23Protein EGL-230.425
C34F6.9Protein C34F6.90.424
tbb-4Protein TBB-40.423
efn-2Protein EFN-20.423
his-16Protein HIS-160.422
syd-9Protein SYD-90.416
nsy-4Protein NSY-40.414
egl-8Protein EGL-80.413
mab-3Protein MAB-30.411
osm-9Protein OSM-90.411
unc-42Protein UNC-420.409
his-4Protein HIS-40.401
bar-1Protein BAR-10.399
che-2Protein CHE-20.397
nhr-2Protein NHR-20.396
let-23Protein LET-230.390
add-1Protein ADD-10.390
ima-3Protein IMA-30.389
mig-2Protein MIG-20.386
tni-1Protein TNI-10.378
tbx-9Protein TBX-90.375
madd-4Protein MADD-40.373
unc-13Protein UNC-130.369
let-60Protein LET-600.368
gei-4Protein GEI-40.366
lin-25Protein LIN-250.366
T28F4.1Protein T28F4.10.364
ast-1Protein AST-10.362
ifb-2Protein IFB-20.357
sax-3Protein SAX-30.352
klp-11Protein KLP-110.352
glr-4Protein GLR-40.349
fln-2Protein FLN-20.348
lin-11Protein LIN-110.348
sax-7Protein SAX-70.348
egl-27Protein EGL-270.346
svh-2Protein SVH-20.344
flap-1Protein FLAP-10.342
gex-3Protein GEX-30.342
K01A2.9Protein K01A2.90.339
sup-12Protein SUP-120.338
nrde-3Protein NRDE-30.335
sng-1Protein SNG-10.335
unc-7Protein UNC-70.334
rnf-113Protein RNF-1130.334
mls-2Protein MLS-20.332
his-48Protein HIS-480.331
fkh-2Protein FKH-20.330
unc-70Protein UNC-700.330
unc-83Protein UNC-830.328
egg-6Protein EGG-60.327
mat-3Protein MAT-30.325
sgt-1Protein SGT-10.322
rol-3Protein ROL-30.321
F08G12.2Protein F08G12.20.319
lin-17Protein LIN-170.318
pkc-1Protein PKC-10.318
dys-1Protein DYS-10.317
his-62Protein HIS-620.317
eat-4Protein EAT-40.316
lrp-1Protein LRP-10.315
lev-11Protein LEV-110.314
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
neurodneurogenic differentiation0.972
lama2laminin, alpha 20.818
fgf3fibroblast growth factor 30.801
pitx2paired-like homeodomain transcription factor 20.648
otpaorthopedia homolog a0.637
chatcholine acetyltransferase0.634
lhx2bLIM homeobox 2b0.607
atp1a3aATPase, Na+/K+ transporting, alpha 3a polypeptide0.602
fezf2FEZ family zinc finger 20.600
atp1b1aATPase, Na+/K+ transporting, beta 1a polypeptide0.588
trpv6transient receptor potential cation channel, subfamily V, member 60.586
otx5orthodenticle homolog 50.578
rx3retinal homeobox gene 30.568
prox1prospero-related homeobox gene 10.518
foxp2forkhead box P20.499
shhbsonic hedgehog b0.487
sncgbsynuclein, gamma b (breast cancer-specific protein 1)0.487
slc12a2solute carrier family 12 (potassium/chloride transporters), member 20.483
myhz2myosin, heavy polypeptide 2, fast muscle specific0.464
crabp1acellular retinoic acid binding protein 1a0.462
cdh23cadherin-like 230.457
chrna1cholinergic receptor, nicotinic, alpha polypeptide 10.447
lmo4aLIM domain only 4a0.441
gnrh3gonadotropin-releasing hormone 30.441
sema3aasemaphorin 3aa0.440
sox1aSRY-box containing gene 1a0.416
scn8aasodium channel, voltage-gated, type VIII, alpha a0.410
celsr3cadherin, EGF LAG seven-pass G-type receptor 30.405
myh6myosin, heavy polypeptide 6, cardiac muscle, alpha0.403
alcambactivated leukocyte cell adhesion molecule b0.402
dbx1adeveloping brain homeobox 1a0.392
actn2actinin, alpha 20.387
lmx1b.1LIM homeobox transcription factor 1, beta 10.373
nos1nitric oxide synthase 1 (neuronal)0.367
lhx1aLIM homeobox 1a0.362
notch1anotch homolog 1a0.353
slc1a2bsolute carrier family 1 (glial high affinity glutamate transporter), member 2b0.352
ndrg4N-myc downstream regulated gene 40.350
spns2spinster homolog 2 (Drosophila)0.347
ddcdopa decarboxylase0.339
mnx1motor neuron and pancreas homeobox 10.329
oprk1opioid receptor, kappa 10.329
dmrt3adoublesex and mab-3 related transcription factor 3a0.324
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.323
wnt8bwingless-type MMTV integration site family, member 8b0.321
olfm2olfactomedin 20.318
ptenbphosphatase and tensin homolog B (mutated in multiple advanced cancers 1)0.312
dccdeleted in colorectal carcinoma0.307
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.306
otpborthopedia homolog b0.301
zic2azic family member 2 (odd-paired homolog, Drosophila), a0.300
smyd1bSET and MYND domain containing 1b0.295
csnk1a1casein kinase 1, alpha 10.295
nxph1neurexophilin 10.295
nr2e3nuclear receptor subfamily 2, group E, member 30.286
tbx18T-box 180.285
aldh1a2aldehyde dehydrogenase 1 family, member A20.284
cacnb1calcium channel, voltage-dependent, beta 1 subunit0.284
trim33tripartite motif-containing 330.280
fgf20afibroblast growth factor 20a0.279
barhl2BarH-like 20.279
myf5myogenic factor 50.277
hand2heart and neural crest derivatives expressed transcript 20.271
dlx5adistal-less homeobox gene 5a0.270
nadl1.1neural adhesion molecule L1.10.269
stmn2bstathmin-like 2b0.264
lef1lymphocyte enhancer binding factor 10.260
dab1adisabled homolog 1a (Drosophila)0.260
ptf1apancreas specific transcription factor, 1a0.259
ptprfprotein tyrosine phosphatase, receptor type, F0.256
foxh1forkhead box H10.254
fgfr2fibroblast growth factor receptor 20.253
elavl3ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)0.252
ptpraprotein tyrosine phosphatase, receptor type, A0.252
dlx1adistal-less homeobox gene 1a0.252
elovl4belongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4b0.249
pcp4aPurkinje cell protein 4a0.246
ca2carbonic anhydrase II0.244
pea3ETS-domain transcription factor pea30.242
unc45bunc-45 homolog B (C. elegans)0.242
itgb1bintegrin, beta 1b0.240
efnb2aephrin B2a0.234
fabp11afatty acid binding protein 11a0.233
trpm7transient receptor potential cation channel, subfamily M, member 70.233
thtyrosine hydroxylase0.230
gria2bglutamate receptor, ionotropic, AMPA 2b0.224
mylz2myosin, light polypeptide 2, skeletal muscle0.222
bmp4bone morphogenetic protein 40.219
ywhaqbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b0.215
gad2glutamate decarboxylase 20.214
foxn4forkhead box N40.211
wnt11rwingless-type MMTV integration site family, member 11, related0.209
plcg1phospholipase C, gamma 10.206
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EGFRepidermal growth factor receptor1.000
CDC42cell division cycle 42 (GTP binding protein, 25kDa)1.000
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.999
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.998
ESR1estrogen receptor 10.998
DLG4discs, large homolog 4 (Drosophila)0.998
GSK3Bglycogen synthase kinase 3 beta0.997
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.996
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.984
INSRinsulin receptor0.973
GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.969
APPamyloid beta (A4) precursor protein0.964
CAV1caveolin 1, caveolae protein, 22kDa0.963
SHC1SHC (Src homology 2 domain containing) transforming protein 10.957
PLCG1phospholipase C, gamma 10.947
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.941
PTPN1protein tyrosine phosphatase, non-receptor type 10.941
RB1retinoblastoma 10.931
FLNAfilamin A, alpha0.928
GRB2growth factor receptor-bound protein 20.913
CREBBPCREB binding protein0.887
AKT1v-akt murine thymoma viral oncogene homolog 10.886
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.883
IGF1Rinsulin-like growth factor 1 receptor0.881
JUNjun proto-oncogene0.865
ATXN1ataxin 10.848
ATF2activating transcription factor 20.846
QKIquaking homolog, KH domain RNA binding (mouse)0.845
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.841
MDM2Mdm2 p53 binding protein homolog (mouse)0.829
FN1fibronectin 10.810
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.796
FGFR1fibroblast growth factor receptor 10.784
NTRK3neurotrophic tyrosine kinase, receptor, type 30.779
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.778
ARandrogen receptor0.776
RBFOX2RNA binding protein, fox-1 homolog (C. elegans) 20.770
TP53tumor protein p530.768
HDAC4histone deacetylase 40.763
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.753
PSEN1presenilin 10.744
NCOR2nuclear receptor corepressor 20.742
EP300E1A binding protein p3000.742
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.740
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.704
PTPN11protein tyrosine phosphatase, non-receptor type 110.699
DNM1dynamin 10.684
KCNA1potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)0.681
SYKspleen tyrosine kinase0.680
IRS1insulin receptor substrate 10.668
JAG1jagged 10.664
CUL1cullin 10.655
NCOR1nuclear receptor corepressor 10.653
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.614
GAB1GRB2-associated binding protein 10.613
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.609
EFTUD2elongation factor Tu GTP binding domain containing 20.592
CUL2cullin 20.591
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.586
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.584
HIPK2homeodomain interacting protein kinase 20.578
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.566
PDIA3protein disulfide isomerase family A, member 30.566
MAPTmicrotubule-associated protein tau0.565
PBX1pre-B-cell leukemia homeobox 10.565
LCKlymphocyte-specific protein tyrosine kinase0.558
LATlinker for activation of T cells0.552
CBX5chromobox homolog 50.547
CRHR1corticotropin releasing hormone receptor 10.540
CASKcalcium/calmodulin-dependent serine protein kinase (MAGUK family)0.539
CEACAM6carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)0.537
CEACAM1carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)0.527
METmet proto-oncogene (hepatocyte growth factor receptor)0.527
PPARAperoxisome proliferator-activated receptor alpha0.525
SRPK2SRSF protein kinase 20.517
PIK3CAphosphoinositide-3-kinase, catalytic, alpha polypeptide0.514
PTENphosphatase and tensin homolog0.513
ADAM10ADAM metallopeptidase domain 100.508
ACTR3ARP3 actin-related protein 3 homolog (yeast)0.508
CCR5chemokine (C-C motif) receptor 50.505
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A0.490
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.489
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.483
SMAD2SMAD family member 20.481
DNM2dynamin 20.470
FHL2four and a half LIM domains 20.453
FUSfused in sarcoma0.452
S100BS100 calcium binding protein B0.442
NR4A1nuclear receptor subfamily 4, group A, member 10.440
NTRK2neurotrophic tyrosine kinase, receptor, type 20.439
GHRgrowth hormone receptor0.433
TAL1T-cell acute lymphocytic leukemia 10.433
CEBPBCCAAT/enhancer binding protein (C/EBP), beta0.422
PRPF8PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)0.420
NCAM1neural cell adhesion molecule 10.415
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.413
DLG1discs, large homolog 1 (Drosophila)0.412
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.411
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism