The network for 'negative regulation of striated muscle contraction' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of striated muscle contraction

Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction.

NameDescriptionProbabilityFunc Analog Organism
Cdc42bpbCDC42 binding protein kinase beta (DMPK-like)0.059
Ank2ankyrin 2, neuronal0.050
Pctk1PCTAIRE protein kinase 10.045
Pfkfb46-phosphofructo-2-kinase/fructose-2,6-biphosphatase 40.037
Adora1adenosine A1 receptor0.027
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.025
Gzmbgranzyme B0.022
Strnstriatin, calmodulin binding protein0.022
Git1G protein-coupled receptor kinase interacting ArfGAP 10.021
Trim28tripartite motif-containing 280.020
Atxn3ataxin 30.019
Tgfbr3transforming growth factor, beta receptor III0.019
Ceacam10carcinoembryonic antigen-related cell adhesion molecule 100.018
Il8rbinterleukin 8 receptor, beta0.018
Pemtphosphatidylethanolamine N-methyltransferase0.017
Cx3cr1chemokine (C-X3-C motif) receptor 10.017
Sparcl1SPARC-like 1 (hevin)0.017
Camta2calmodulin binding transcription activator 20.016
Slc1a3solute carrier family 1 (glial high affinity glutamate transporter), member 30.014
Tfectranscription factor EC0.014
Smad3SMAD family member 30.013
Ppyr1pancreatic polypeptide receptor 10.012
Ptmsparathymosin0.012
Aqp4aquaporin 40.012
Shox2short stature homeobox 20.012
Mbpmyelin basic protein0.012
Olig1oligodendrocyte transcription factor 10.011
Batf3basic leucine zipper transcription factor, ATF-like 30.011
Ptafrplatelet-activating factor receptor0.011
Sfrp4secreted frizzled-related protein 40.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
HDAC6histone deacetylase 61.000
GIT1G protein-coupled receptor kinase interacting ArfGAP 10.994
PDE6Gphosphodiesterase 6G, cGMP-specific, rod, gamma0.164
PPP6R1protein phosphatase 6, regulatory subunit 10.139
PRKCAprotein kinase C, alpha0.116
ATP13A2ATPase type 13A20.112
KCNIP3Kv channel interacting protein 3, calsenilin0.103
RASGRF1Ras protein-specific guanine nucleotide-releasing factor 10.068
MIIPmigration and invasion inhibitory protein0.060
CANXcalnexin0.059
ADORA2Aadenosine A2a receptor0.058
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.044
CYLDcylindromatosis (turban tumor syndrome)0.042
LDB3LIM domain binding 30.036
ZRANB1zinc finger, RAN-binding domain containing 10.032
HDAC11histone deacetylase 110.032
ADRBK1adrenergic, beta, receptor kinase 10.029
HTThuntingtin0.028
SIRT2sirtuin 20.026
SH3BP1SH3-domain binding protein 10.023
PYGMphosphorylase, glycogen, muscle0.022
ZMYM3zinc finger, MYM-type 30.020
MYLPFmyosin light chain, phosphorylatable, fast skeletal muscle0.020
TAZtafazzin0.020
HMOX2heme oxygenase (decycling) 20.019
G6PDglucose-6-phosphate dehydrogenase0.019
ADRBK2adrenergic, beta, receptor kinase 20.019
CLN6ceroid-lipofuscinosis, neuronal 6, late infantile, variant0.018
CTTNcortactin0.017
CHD3chromodomain helicase DNA binding protein 30.017
TAB1TGF-beta activated kinase 1/MAP3K7 binding protein 10.017
ACTN3actinin, alpha 30.015
GIT2G protein-coupled receptor kinase interacting ArfGAP 20.015
POLHpolymerase (DNA directed), eta0.015
CSKc-src tyrosine kinase0.015
ITPR3inositol 1,4,5-trisphosphate receptor, type 30.015
GMIPGEM interacting protein0.015
ARHGAP4Rho GTPase activating protein 40.014
TNNC1troponin C type 1 (slow)0.013
ZFAND5zinc finger, AN1-type domain 50.013
TNNT3troponin T type 3 (skeletal, fast)0.013
UBASH3Bubiquitin associated and SH3 domain containing B0.013
IMPDH1IMP (inosine 5'-monophosphate) dehydrogenase 10.013
EGFepidermal growth factor0.013
TNNI2troponin I type 2 (skeletal, fast)0.012
PTP4A3protein tyrosine phosphatase type IVA, member 30.012
MYH7myosin, heavy chain 7, cardiac muscle, beta0.012
PRSS23protease, serine, 230.012
SH3KBP1SH3-domain kinase binding protein 10.012
CD79ACD79a molecule, immunoglobulin-associated alpha0.011
TRABDTraB domain containing0.011
EIF1eukaryotic translation initiation factor 10.011
LPAR2lysophosphatidic acid receptor 20.011
TNNC2troponin C type 2 (fast)0.011
NBEAL2neurobeachin-like 20.011
PTPN1protein tyrosine phosphatase, non-receptor type 10.010
RGS14regulator of G-protein signaling 140.010
ATF2activating transcription factor 20.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism