The network for 'protein autoubiquitination' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

protein autoubiquitination

The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.

NameDescriptionProbabilityFunc Analog Organism
Eif3ieukaryotic translation initiation factor 3, subunit I0.018
Ndufb10NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 100.015
Psmb1proteasome (prosome, macropain) subunit, beta type 10.015
RGD1304704similar to Hypothetical protein CGI-990.013
Psmb6proteasome (prosome, macropain) subunit, beta type 60.012
Psmb4proteasome (prosome, macropain) subunit, beta type 40.012
Mrpl22mitochondrial ribosomal protein L220.012
Atp5hATP synthase, H+ transporting, mitochondrial F0 complex, subunit d0.012
Mrpl27mitochondrial ribosomal protein L270.011
Erhenhancer of rudimentary homolog (Drosophila)0.011
Tceb2transcription elongation factor B (SIII), polypeptide 20.011
Atp5oATP synthase, H+ transporting, mitochondrial F1 complex, O subunit0.011
Cct5chaperonin containing Tcp1, subunit 5 (epsilon)0.010
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.256
tp53tumor protein p530.058
mibmind bomb0.051
notch1anotch homolog 1a0.035
ikzf5IKAROS family zinc finger 50.032
sema3hsemaphorin 3h0.029
dzip1DAZ interacting protein 10.025
cry5cryptochrome 50.022
tfectranscription factor EC0.016
xpcxeroderma pigmentosum, complementation group C0.015
wnt5awingless-type MMTV integration site family, member 5a0.013
irak4interleukin-1 receptor-associated kinase 40.012
rereaarginine-glutamic acid dipeptide (RE) repeats a0.011
mstnamyostatin a0.011
wdr76WD repeat domain 760.011
hoxa13ahomeo box A13a0.011
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
RNF11ring finger protein 111.000
UBE2D2ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)1.000
RNF5ring finger protein 51.000
UBE2D3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.999
TRAF6TNF receptor-associated factor 60.998
UBE2V1ubiquitin-conjugating enzyme E2 variant 10.997
XIAPX-linked inhibitor of apoptosis0.997
TRIM39tripartite motif containing 390.989
ZNRF1zinc and ring finger 10.989
RNF111ring finger protein 1110.983
TRAF3TNF receptor-associated factor 30.978
UBE2Nubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)0.961
TRIM8tripartite motif containing 80.925
UBE2D1ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)0.919
SMURF1SMAD specific E3 ubiquitin protein ligase 10.916
OTUB1OTU domain, ubiquitin aldehyde binding 10.913
TRAF2TNF receptor-associated factor 20.887
SMURF2SMAD specific E3 ubiquitin protein ligase 20.884
ARIH2ariadne homolog 2 (Drosophila)0.879
MIB1mindbomb homolog 1 (Drosophila)0.826
UBE2E1ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)0.808
RNF14ring finger protein 140.792
TRIM27tripartite motif containing 270.753
SIAH1seven in absentia homolog 1 (Drosophila)0.729
BFARbifunctional apoptosis regulator0.725
BIRC2baculoviral IAP repeat containing 20.703
CHD4chromodomain helicase DNA binding protein 40.699
DZIP3DAZ interacting protein 3, zinc finger0.670
DTX3Ldeltex 3-like (Drosophila)0.663
TRIM43tripartite motif containing 430.648
RNF114ring finger protein 1140.628
MARCH7membrane-associated ring finger (C3HC4) 70.584
RNF38ring finger protein 380.571
TRIM63tripartite motif containing 630.544
TRIM5tripartite motif containing 50.541
BIRC3baculoviral IAP repeat containing 30.526
RNF4ring finger protein 40.493
RNF130ring finger protein 1300.466
UBE2D4ubiquitin-conjugating enzyme E2D 4 (putative)0.466
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.443
ERCC6excision repair cross-complementing rodent repair deficiency, complementation group 60.438
VCPvalosin containing protein0.412
CHFRcheckpoint with forkhead and ring finger domains0.393
GFM1G elongation factor, mitochondrial 10.370
SMAD4SMAD family member 40.360
UBE3Aubiquitin protein ligase E3A0.357
NEDD4neural precursor cell expressed, developmentally down-regulated 40.331
UBE2Hubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)0.329
TRIM32tripartite motif containing 320.323
MDM2Mdm2 p53 binding protein homolog (mouse)0.321
TNFRSF14tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)0.317
PJA2praja ring finger 20.289
MARCH5membrane-associated ring finger (C3HC4) 50.275
GTF2H2general transcription factor IIH, polypeptide 2, 44kDa0.274
FBXL15F-box and leucine-rich repeat protein 150.244
ZMYND11zinc finger, MYND-type containing 110.244
MBD3methyl-CpG binding domain protein 30.225
AMFRautocrine motility factor receptor0.201
MTA2metastasis associated 1 family, member 20.195
ZNF746zinc finger protein 7460.194
MED15mediator complex subunit 150.190
SMAD1SMAD family member 10.171
HDAC1histone deacetylase 10.162
UBE2E3ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)0.158
UBE2Bubiquitin-conjugating enzyme E2B (RAD6 homolog)0.153
KDM1Alysine (K)-specific demethylase 1A0.149
TSG101tumor susceptibility gene 1010.144
ZNF263zinc finger protein 2630.138
RNF10ring finger protein 100.136
WWP2WW domain containing E3 ubiquitin protein ligase 20.128
ING2inhibitor of growth family, member 20.124
MTA1metastasis associated 10.114
DNMT3BDNA (cytosine-5-)-methyltransferase 3 beta0.112
LIN28Blin-28 homolog B (C. elegans)0.111
ATXN3ataxin 30.109
BIRC8baculoviral IAP repeat containing 80.107
MDM4Mdm4 p53 binding protein homolog (mouse)0.106
ANKRD13Aankyrin repeat domain 13A0.106
RNF2ring finger protein 20.103
UBE2L3ubiquitin-conjugating enzyme E2L 30.101
DDX58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.101
GATAD2AGATA zinc finger domain containing 2A0.100
MTA3metastasis associated 1 family, member 30.097
MUL1mitochondrial E3 ubiquitin protein ligase 10.097
UBE2Aubiquitin-conjugating enzyme E2A (RAD6 homolog)0.094
KPNA1karyopherin alpha 1 (importin alpha 5)0.092
RNF168ring finger protein 1680.092
CD40CD40 molecule, TNF receptor superfamily member 50.091
UBE2Uubiquitin-conjugating enzyme E2U (putative)0.090
GATAD2BGATA zinc finger domain containing 2B0.088
RNF126ring finger protein 1260.087
RNF166ring finger protein 1660.087
UBR1ubiquitin protein ligase E3 component n-recognin 10.083
DDB1damage-specific DNA binding protein 1, 127kDa0.077
NPLOC4nuclear protein localization 4 homolog (S. cerevisiae)0.076
ZRANB1zinc finger, RAN-binding domain containing 10.076
LRSAM1leucine rich repeat and sterile alpha motif containing 10.074
TRIM25tripartite motif containing 250.072
RLIMring finger protein, LIM domain interacting0.070
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Tax1bp1Tax1 (human T-cell leukemia virus type I) binding protein 10.015
Usp8ubiquitin specific peptidase 80.014
Tnfaip3tumor necrosis factor, alpha-induced protein 30.013
Traf6TNF receptor-associated factor 60.013
Map3k7mitogen-activated protein kinase kinase kinase 70.011
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism