The network for 'pteridine containing compound metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

pteridine containing compound metabolic process

The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.

Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Dhfrdihydrofolate reductase0.691
RGD1307752similar to RIKEN cDNA 1110008F130.447
Ndufc1NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 10.316
Ahcyadenosylhomocysteinase0.299
LOC494499LOC494499 protein0.269
Shmt1serine hydroxymethyltransferase 1 (soluble)0.250
Slc30a2solute carrier family 30 (zinc transporter), member 20.190
Mlh1mutL homolog 1 (E. coli)0.184
Grpel1GrpE-like 1, mitochondrial0.134
Hmbshydroxymethylbilane synthase0.134
Unguracil-DNA glycosylase0.105
RGD1305347similar to RIKEN cDNA 2610528J110.104
Nr1h4nuclear receptor subfamily 1, group H, member 40.101
Pctpphosphatidylcholine transfer protein0.077
Hmox1heme oxygenase (decycling) 10.073
Haghhydroxyacyl glutathione hydrolase0.064
Cenpicentromere protein I0.062
Casp6caspase 60.056
Rbp2retinol binding protein 2, cellular0.054
Rnaseh2bribonuclease H2, subunit B0.054
LOC100365112carboxylesterase-like0.053
Hn1lhematological and neurological expressed 1-like0.053
Serpina5serine (or cysteine) peptidase inhibitor, clade A, member 50.049
Litaflipopolysaccharide-induced TNF factor0.049
Mgst2microsomal glutathione S-transferase 20.047
Foxm1forkhead box M10.047
Rad51cRad51 homolog c (S. cerevisiae)0.047
Kmokynurenine 3-monooxygenase (kynurenine 3-hydroxylase)0.045
Hpd4-hydroxyphenylpyruvate dioxygenase0.044
Ass1argininosuccinate synthetase 10.043
Bmp7bone morphogenetic protein 70.042
Acsm3acyl-CoA synthetase medium-chain family member 30.041
Aldh7a1aldehyde dehydrogenase 7 family, member A10.041
Pola1polymerase (DNA directed), alpha 10.039
FanccFanconi anemia, complementation group C0.037
Il1rninterleukin 1 receptor antagonist0.035
Sf3b3splicing factor 3b, subunit 30.031
Ppp1r3bprotein phosphatase 1, regulatory (inhibitor) subunit 3B0.031
Ugt2b36UDP glucuronosyltransferase 2 family, polypeptide B360.031
Casp7caspase 70.031
Asnsasparagine synthetase0.030
Aldh4a1aldehyde dehydrogenase 4 family, member A10.029
Bhmtbetaine-homocysteine methyltransferase0.029
Polr1bpolymerase (RNA) I polypeptide B0.028
Ogg18-oxoguanine DNA glycosylase0.028
Ppifpeptidylprolyl isomerase F0.027
Brca1breast cancer 10.027
FasFas (TNF receptor superfamily, member 6)0.027
Shmt2serine hydroxymethyltransferase 2 (mitochondrial)0.026
Ndufs4NADH dehydrogenase (ubiquinone) Fe-S protein 40.025
Mat1amethionine adenosyltransferase I, alpha0.025
Ruvbl1RuvB-like 1 (E. coli)0.025
Farsbphenylalanyl-tRNA synthetase, beta subunit0.025
Tk1thymidine kinase 1, soluble0.024
Wdr77WD repeat domain 770.024
Nipsnap1nipsnap homolog 1 (C. elegans)0.024
Tdo2tryptophan 2,3-dioxygenase0.023
Mipepmitochondrial intermediate peptidase0.023
RGD1304693similar to CG14803-PA0.023
Acy1aminoacylase 10.023
Dhcr77-dehydrocholesterol reductase0.022
RGD1566085similar to pyridoxal (pyridoxine, vitamin B6) kinase0.022
Acppacid phosphatase, prostate0.022
Mcm5minichromosome maintenance complex component 50.022
Ndufa3NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 30.021
Slc19a1solute carrier family 19 (folate transporter), member 10.021
Cited1Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 10.021
Acacbacetyl-Coenzyme A carboxylase beta0.020
Hmmrhyaluronan mediated motility receptor (RHAMM)0.019
Cyp2c7cytochrome P450, family 2, subfamily c, polypeptide 70.019
Qdprquinoid dihydropteridine reductase0.019
Tmem9bTMEM9 domain family, member B0.019
Fkbp4FK506 binding protein 40.019
Cyb5acytochrome b5 type A (microsomal)0.019
Igfl3IGF-like family member 30.019
Mcm2minichromosome maintenance complex component 20.018
Cyp2d2cytochrome P450, family 2, subfamily d, polypeptide 20.018
Psat1phosphoserine aminotransferase 10.018
Nsun4NOL1/NOP2/Sun domain family, member 40.018
Slc25a13solute carrier family 25, member 13 (citrin)0.018
Nrg1neuregulin 10.017
Ceacam10carcinoembryonic antigen-related cell adhesion molecule 100.017
Polr1epolymerase (RNA) I polypeptide E0.017
Hadhhydroxyacyl-Coenzyme A dehydrogenase0.017
Mthfd1methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase0.017
Slc7a1solute carrier family 7 (cationic amino acid transporter, y+ system), member 10.017
Ndufa4NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 40.017
Tmpothymopoietin0.017
Ccne1cyclin E10.017
Agxt2alanine-glyoxylate aminotransferase 20.017
Rpa2replication protein A20.017
Sp4Sp4 transcription factor0.017
Procprotein C0.017
Olr1701olfactory receptor 17010.017
Akr1c14aldo-keto reductase family 1, member C140.017
Ak2adenylate kinase 20.016
Cdk2cyclin dependent kinase 20.016
Dnah9dynein, axonemal, heavy polypeptide 90.016
Srd5a1steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)0.016
RGD1305274similar to RIKEN cDNA 2010305A190.016
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
tymsthymidylate synthase0.050
mthfd1methylenetetrahydrofolate dehydrogenase (NADP+ dependent)0.020
LOC557072caspase recruitment domain-containing protein 11-like0.019
mtr5-methyltetrahydrofolate-homocysteine methyltransferase0.013
pycardPYD and CARD domain containing0.011
robo2roundabout homolog 20.010
akap9A kinase (PRKA) anchor protein (yotiao) 90.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
ade3adenosine 30.456
vvermilion0.183
HnHenna0.083
ade2adenosine 20.059
ade5CG3989 gene product from transcript CG3989-RA0.059
cincinnamon0.043
bwbrown0.042
TalCG2827 gene product from transcript CG2827-RA0.039
pugpugilist0.037
CG8036CG8036 gene product from transcript CG8036-RB0.019
CG11089CG11089 gene product from transcript CG11089-RD0.017
CG3011CG3011 gene product from transcript CG3011-RA0.016
PgdPhosphogluconate dehydrogenase0.014
plepale0.013
CG11255CG11255 gene product from transcript CG11255-RA0.012
mTTFmitochondrial transcription termination factor0.012
stjstraightjacket0.012
sesepia0.011
OatOrnithine aminotransferase precursor0.011
pnprune0.011
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
MMEmembrane metallo-endopeptidase0.216
WRAP73WD repeat containing, antisense to TP730.041
KIAA0101KIAA01010.035
MCM2minichromosome maintenance complex component 20.027
CDT1chromatin licensing and DNA replication factor 10.016
EIF4EBP1eukaryotic translation initiation factor 4E binding protein 10.016
LDHAlactate dehydrogenase A0.015
UNGuracil-DNA glycosylase0.012
USP50ubiquitin specific peptidase 500.011
CASP4caspase 4, apoptosis-related cysteine peptidase0.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Slc11a2solute carrier family 11 (proton-coupled divalent metal ion transporters), member 20.179
Asnsasparagine synthetase0.141
Hpd4-hydroxyphenylpyruvic acid dioxygenase0.077
Slc26a1solute carrier family 26 (sulfate transporter), member 10.055
Slc40a1solute carrier family 40 (iron-regulated transporter), member 10.047
Pex7peroxisomal biogenesis factor 70.042
BC048355cDNA sequence BC0483550.037
Zfp871zinc finger protein 8710.033
Slc7a5solute carrier family 7 (cationic amino acid transporter, y+ system), member 50.032
Mll5myeloid/lymphoid or mixed-lineage leukemia 50.027
Psat1phosphoserine aminotransferase 10.024
Pts6-pyruvoyl-tetrahydropterin synthase0.024
Shmt2serine hydroxymethyltransferase 2 (mitochondrial)0.021
Prodh2proline dehydrogenase (oxidase) 20.020
Zmynd11zinc finger, MYND domain containing 110.018
Nipsnap14-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)0.018
Apomapolipoprotein M0.016
F13bcoagulation factor XIII, beta subunit0.015
Ifrd2interferon-related developmental regulator 20.015
Slc4a1solute carrier family 4 (anion exchanger), member 10.015
Serpina6serine (or cysteine) peptidase inhibitor, clade A, member 60.015
Iarsisoleucine-tRNA synthetase0.014
Acy1aminoacylase 10.013
Sdslserine dehydratase-like0.013
Fam13bfamily with sequence similarity 13, member B0.013
Bhmt2betaine-homocysteine methyltransferase 20.013
Gjb1gap junction protein, beta 10.013
Acadmacyl-Coenzyme A dehydrogenase, medium chain0.013
Abcc6ATP-binding cassette, sub-family C (CFTR/MRP), member 60.013
Dhrs4dehydrogenase/reductase (SDR family) member 40.013
Sprsepiapterin reductase0.012
Nischnischarin0.012
Slc6a13solute carrier family 6 (neurotransmitter transporter, GABA), member 130.012
Macf1microtubule-actin crosslinking factor 10.012
Mceemethylmalonyl CoA epimerase0.011
Jmjd1cjumonji domain containing 1C0.011
Aldh18a1aldehyde dehydrogenase 18 family, member A10.011
Unguracil DNA glycosylase0.010
Gcgrglucagon receptor0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism