The network for 'negative regulation of defecation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of defecation

Any process that stops, prevents or reduces the frequency, rate or extent of defecation.

NameDescriptionProbabilityFunc Analog Organism
Cacna1acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.147
Slc14a2solute carrier family 14 (urea transporter), member 20.140
Olr1867olfactory receptor 18670.113
Atp2a3ATPase, Ca++ transporting, ubiquitous0.100
LOC56764dnaj-like protein0.094
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.094
Gpr1G protein-coupled receptor 10.093
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.075
Gzmkgranzyme K0.073
Adam10ADAM metallopeptidase domain 100.067
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.062
Ncanneurocan0.062
Olr1078olfactory receptor 10780.061
Notch3Notch homolog 3 (Drosophila)0.059
Il9rinterleukin 9 receptor0.059
P2rx3purinergic receptor P2X, ligand-gated ion channel, 30.057
Magmyelin-associated glycoprotein0.056
RhdRh blood group, D antigen0.054
Zic1Zic family member 1 (odd-paired homolog, Drosophila)0.053
RGD1306474similar to RIKEN cDNA 9530003J230.052
Gja6gap junction protein, alpha 60.051
Kcnc3potassium voltage gated channel, Shaw-related subfamily, member 30.046
Bcl2l10BCL2-like 10 (apoptosis facilitator)0.046
FaslgFas ligand (TNF superfamily, member 6)0.046
N5DNA binding protein N50.045
Gabrg1gamma-aminobutyric acid (GABA) A receptor, gamma 10.045
Slc8a3solute carrier family 8 (sodium/calcium exchanger), member 30.043
Lims1LIM and senescent cell antigen-like domains 10.042
Slc22a25solute carrier family 22, member 250.041
Csf1colony stimulating factor 1 (macrophage)0.041
Adora2aadenosine A2a receptor0.040
Oprk1opioid receptor, kappa 10.039
MrgprfMAS-related GPR, member F0.037
Avparginine vasopressin0.037
Ghrhrgrowth hormone releasing hormone receptor0.036
Pde1bphosphodiesterase 1B, calmodulin-dependent0.035
Fxyd4FXYD domain-containing ion transport regulator 40.035
Chrm2cholinergic receptor, muscarinic 20.034
Csn2casein beta0.033
Foxa1forkhead box A10.033
Dccdeleted in colorectal carcinoma0.033
Mcpt3mast cell peptidase 30.032
Mpp2membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)0.032
Nkx6-1NK6 homeobox 10.032
Colqcollagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase0.032
Pspparotid secretory protein0.031
Nmbrneuromedin B receptor0.031
Atp2b4ATPase, Ca++ transporting, plasma membrane 40.030
FevFEV (ETS oncogene family)0.029
Acrv1acrosomal vesicle protein 10.028
Wfdc6aWAP four-disulfide core domain 6A0.028
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.027
Gcnt3glucosaminyl (N-acetyl) transferase 3, mucin type0.026
Olr1641olfactory receptor 16410.026
St8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.025
Nkg7natural killer cell group 7 sequence0.024
Grin1glutamate receptor, ionotropic, N-methyl D-aspartate 10.024
Syt7synaptotagmin VII0.024
Neurog3neurogenin 30.024
Phox2apaired-like homeobox 2a0.024
Scn4asodium channel, voltage-gated, type IV, alpha subunit0.023
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.023
Grprgastrin releasing peptide receptor0.023
St6galnac3ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 30.023
Olr1496olfactory receptor 14960.023
Thtyrosine hydroxylase0.023
Hap1huntingtin-associated protein 10.023
Slc5a2solute carrier family 5 (sodium/glucose cotransporter), member 20.022
Npffr2neuropeptide FF receptor 20.022
Barhl1BarH-like homeobox 10.022
Znf575zinc finger protein 5750.022
UncxUNC homeobox0.021
Chrngcholinergic receptor, nicotinic, gamma0.021
Drd3dopamine receptor D30.021
Fgf7fibroblast growth factor 70.021
Gabrg3gamma-aminobutyric acid (GABA) A receptor, gamma 30.021
Plinperilipin0.020
Olr1493olfactory receptor gene Olr14930.020
Psgb1pregnancy-specific beta 1-glycoprotein0.020
Testintestin gene0.020
Utrnutrophin0.020
Gpr176G protein-coupled receptor 1760.020
Cyp27b1cytochrome P450, family 27, subfamily b, polypeptide 10.020
Hand1heart and neural crest derivatives expressed 10.020
Phkg1phosphorylase kinase, gamma 10.020
Hrh3histamine receptor H30.020
Prl2a1Prolactin family 2, subfamily a, member 10.020
Cdk5r1cyclin-dependent kinase 5, regulatory subunit 10.020
Slc4a1solute carrier family 4 (anion exchanger), member 10.020
Ifna1interferon-alpha 10.020
FanccFanconi anemia, complementation group C0.019
Kcna3potassium voltage-gated channel, shaker-related subfamily, member 30.019
Oprl1opiate receptor-like 10.019
Tgfbr3transforming growth factor, beta receptor III0.019
Cx3cr1chemokine (C-X3-C motif) receptor 10.019
Olr37olfactory receptor 370.019
Rin1Ras and Rab interactor 10.019
Chst10carbohydrate sulfotransferase 100.019
Kcnj6potassium inwardly-rectifying channel, subfamily J, member 60.019
Smgbneonatal submandibular gland protein B0.018
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism