The network for 'cardiac muscle tissue growth' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cardiac muscle tissue growth

The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.

NameDescriptionProbabilityFunc Analog Organism
Cav1caveolin 1, caveolae protein0.426
Ahsgalpha-2-HS-glycoprotein0.334
LOC100362824caveolin 2-like0.143
Kcnq3potassium voltage-gated channel, KQT-like subfamily, member 30.105
Albalbumin0.104
Top2atopoisomerase (DNA) II alpha0.102
Nos3nitric oxide synthase 3, endothelial cell0.093
Syt8synaptotagmin VIII0.091
Rararetinoic acid receptor, alpha0.082
Cav2caveolin 20.081
Scn5asodium channel, voltage-gated, type V, alpha subunit0.060
Tnni1troponin I type 1 (skeletal, slow)0.057
Unc5bunc-5 homolog B (C. elegans)0.057
Tacr2tachykinin receptor 20.055
Ube2cubiquitin-conjugating enzyme E2C0.048
Dmddystrophin0.046
Cdk1cyclin-dependent kinase 10.045
Gja3gap junction protein, alpha 30.039
Vom2r27vomeronasal 2 receptor, 270.038
Kcng2potassium voltage-gated channel, subfamily G, member 20.036
Prl8a2prolactin family 8, subfamily a, member 20.035
Racgap1Rac GTPase-activating protein 10.035
Synposynaptopodin0.035
Smad7SMAD family member 70.034
Ccnb1cyclin B10.033
Apohapolipoprotein H (beta-2-glycoprotein I)0.033
Mapk8mitogen-activated protein kinase 80.033
Slc1a6solute carrier family 1 (high affinity aspartate/glutamate transporter), member 60.032
Serpina11serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 110.031
Igfbp5insulin-like growth factor binding protein 50.030
Timp3TIMP metallopeptidase inhibitor 30.029
Camkk2calcium/calmodulin-dependent protein kinase kinase 2, beta0.029
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.028
Smad3SMAD family member 30.028
Foxi2forkhead box I20.027
Folh1folate hydrolase 10.027
Fgafibrinogen alpha chain0.027
Gipgastric inhibitory polypeptide0.027
Pttg1pituitary tumor-transforming 10.027
Adarb2adenosine deaminase, RNA-specific, B20.026
Tgfbr2transforming growth factor, beta receptor II0.026
Phkg1phosphorylase kinase, gamma 10.025
Htr1d5-hydroxytryptamine (serotonin) receptor 1D0.025
Azgp1alpha-2-glycoprotein 1, zinc-binding0.025
Leprleptin receptor0.024
Cacng8calcium channel, voltage-dependent, gamma subunit 80.024
Fgbfibrinogen beta chain0.024
Hand2heart and neural crest derivatives expressed 20.024
Lims1LIM and senescent cell antigen-like domains 10.023
Muskmuscle, skeletal, receptor tyrosine kinase0.023
Ncanneurocan0.023
Pitx1paired-like homeodomain 10.023
Vdrvitamin D (1,25- dihydroxyvitamin D3) receptor0.023
Prap1proline-rich acidic protein 10.022
Svs1seminal vesicle secretory protein 10.022
Slco2a1solute carrier organic anion transporter family, member 2a10.022
Ebf1early B-cell factor 10.021
Fgf16fibroblast growth factor 160.021
Gata6GATA binding protein 60.021
Trib1tribbles homolog 1 (Drosophila)0.021
Prrx1paired related homeobox 10.021
Atp12aATPase, H+/K+ transporting, nongastric, alpha polypeptide0.021
Ppardperoxisome proliferator-activated receptor delta0.020
Traf4af1TRAF4 associated factor 10.020
LOC689399hypothetical protein LOC6893990.020
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.020
Tpc1808tropic 18080.020
Prkcaprotein kinase C, alpha0.020
Notch2Notch homolog 2 (Drosophila)0.019
Apoa2apolipoprotein A-II0.019
Sox17SRY (sex determining region Y)-box 170.019
Foxa3forkhead box A30.019
Hspb3heat shock protein 30.019
Efnb1ephrin B10.019
Tontonin0.019
Serpine2serine (or cysteine) peptidase inhibitor, clade E, member 20.018
Hoxb7homeo box B70.018
Nfibnuclear factor I/B0.018
Rrm2ribonucleotide reductase M20.018
Appamyloid beta (A4) precursor protein0.018
RGD1309821similar to KIAA1161 protein0.018
Aqp3aquaporin 30.018
Orm1orosomucoid 10.018
Ghrgrowth hormone receptor0.018
Cyp2c22cytochrome P450, family 2, subfamily c, polypeptide 220.017
Wt1Wilms tumor 10.017
Lifleukemia inhibitory factor0.017
Pde4aphosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila)0.017
Agtr1bangiotensin II receptor, type 1b0.017
Pqcppolyglutamine-containing protein0.017
Testintestin gene0.017
Iappislet amyloid polypeptide0.017
Pecam1platelet/endothelial cell adhesion molecule 10.017
UncxUNC homeobox0.017
Apcsamyloid P component, serum0.016
Col10a1collagen, type X, alpha 10.016
Mmp10matrix metallopeptidase 100.016
Gabrg1gamma-aminobutyric acid (GABA) A receptor, gamma 10.016
Kcnab1potassium voltage-gated channel, shaker-related subfamily, beta member 10.016
Nek9NIMA (never in mitosis gene a)- related kinase 90.016
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
tbx1T-box 10.147
hey2hairy/enhancer-of-split related with YRPW motif 20.052
mef2cbmyocyte enhancer factor 2cb0.034
tbx20T-box 200.032
nkx2.5NK2 transcription factor related 50.029
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.018
hand2heart and neural crest derivatives expressed transcript 20.017
myl7myosin, light polypeptide 7, regulatory0.017
crip2cysteine-rich protein 20.016
dkk1bdickkopf 1b0.015
fn1fibronectin 10.015
spawsouthpaw0.015
gpiaglucose phosphate isomerase a0.015
lhx2bLIM homeobox 2b0.014
tbx5aT-box 5a0.014
rbpms2RNA binding protein with multiple splicing 20.014
wif1wnt inhibitory factor 10.014
tgfb3transforming growth factor, beta 30.014
lft2lefty20.013
myh6myosin, heavy polypeptide 6, cardiac muscle, alpha0.013
gata4GATA-binding protein 40.011
tbx2bT-box 2b0.011
rbfox1lRNA binding protein, fox-1 homolog (C. elegans) 1-like0.011
tbx2aT-box gene 2a0.011
flt4fms-related tyrosine kinase 40.011
twist2twist20.011
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
FGFR2fibroblast growth factor receptor 20.999
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.876
TBX5T-box 50.835
RARAretinoic acid receptor, alpha0.609
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.453
FGF1fibroblast growth factor 1 (acidic)0.277
HDAC1histone deacetylase 10.257
UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)0.209
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.158
MDM2Mdm2 p53 binding protein homolog (mouse)0.126
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.109
FGF10fibroblast growth factor 100.099
TGFB3transforming growth factor, beta 30.094
CDK2cyclin-dependent kinase 20.079
MED25mediator complex subunit 250.077
ENGendoglin0.075
JAG1jagged 10.074
HDAC4histone deacetylase 40.073
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.060
MAPK9mitogen-activated protein kinase 90.056
NOTCH1notch 10.053
FSTL1follistatin-like 10.045
SMAD3SMAD family member 30.041
NEDD4neural precursor cell expressed, developmentally down-regulated 40.034
TTRtransthyretin0.032
GATA4GATA binding protein 40.031
WWOXWW domain containing oxidoreductase0.028
TGFB1transforming growth factor, beta 10.028
SPOPspeckle-type POZ protein0.025
ATXN1Lataxin 1-like0.025
TGFBR1transforming growth factor, beta receptor 10.025
SMAD7SMAD family member 70.024
FGF7fibroblast growth factor 70.024
EP300E1A binding protein p3000.024
MAML1mastermind-like 1 (Drosophila)0.023
CREBBPCREB binding protein0.021
SATB2SATB homeobox 20.020
CCNA2cyclin A20.017
ANKS1Bankyrin repeat and sterile alpha motif domain containing 1B0.016
YAP1Yes-associated protein 10.016
MAPK8mitogen-activated protein kinase 80.015
MAP3K1mitogen-activated protein kinase kinase kinase 10.014
PRKACAprotein kinase, cAMP-dependent, catalytic, alpha0.013
KRT5keratin 50.013
STK3serine/threonine kinase 30.013
CABLES1Cdk5 and Abl enzyme substrate 10.013
CDK1cyclin-dependent kinase 10.013
MEF2Amyocyte enhancer factor 2A0.012
RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 50.012
NCOR2nuclear receptor corepressor 20.011
NOTCH3notch 30.011
ITCHitchy E3 ubiquitin protein ligase homolog (mouse)0.010
KRT6Ckeratin 6C0.010
DLG4discs, large homolog 4 (Drosophila)0.010
NRP1neuropilin 10.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)1.000
Shhsonic hedgehog0.999
Fgfr2fibroblast growth factor receptor 20.999
Foxc1forkhead box C10.992
Ctnnb1catenin (cadherin associated protein), beta 10.975
Bmp4bone morphogenetic protein 40.969
Hand2heart and neural crest derivatives expressed transcript 20.965
Gli3GLI-Kruppel family member GLI30.961
Pax2paired box gene 20.961
Tbx1T-box 10.951
Fgf8fibroblast growth factor 80.937
Tbx3T-box 30.932
Gata4GATA binding protein 40.925
Pitx2paired-like homeodomain transcription factor 20.921
Notch1Notch gene homolog 1 (Drosophila)0.905
Ptpn11protein tyrosine phosphatase, non-receptor type 110.904
Itgb1integrin beta 1 (fibronectin receptor beta)0.900
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.895
Rxraretinoid X receptor alpha0.876
Smad4MAD homolog 4 (Drosophila)0.839
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.825
Hoxa1homeobox A10.811
Apcadenomatosis polyposis coli0.788
Flt4FMS-like tyrosine kinase 40.781
Sox9SRY-box containing gene 90.770
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.765
Tgfb2transforming growth factor, beta 20.740
Gli2GLI-Kruppel family member GLI20.708
Hand1heart and neural crest derivatives expressed transcript 10.703
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.672
Vangl2vang-like 2 (van gogh, Drosophila)0.669
Pax3paired box gene 30.644
Alx4aristaless-like homeobox 40.642
Nos3nitric oxide synthase 3, endothelial cell0.637
Jag1jagged 10.618
Pou4f3POU domain, class 4, transcription factor 30.605
Nognoggin0.583
Wt1Wilms tumor 1 homolog0.582
Nkx2-1NK2 homeobox 10.573
Hoxd13homeobox D130.567
Smad3MAD homolog 3 (Drosophila)0.565
Tgfbr2transforming growth factor, beta receptor II0.558
Nodalnodal0.557
Fgf10fibroblast growth factor 100.545
Smad6MAD homolog 6 (Drosophila)0.532
Foxc2forkhead box C20.529
Ptenphosphatase and tensin homolog0.496
Ntf3neurotrophin 30.489
Efnb2ephrin B20.489
Zfpm2zinc finger protein, multitype 20.487
Ror2receptor tyrosine kinase-like orphan receptor 20.485
Tbx5T-box 50.477
Fgfr3fibroblast growth factor receptor 30.438
Hey2hairy/enhancer-of-split related with YRPW motif 20.433
Lhx1LIM homeobox protein 10.413
Pthlhparathyroid hormone-like peptide0.412
Isl1ISL1 transcription factor, LIM/homeodomain0.408
Fgfr1fibroblast growth factor receptor 10.393
Hif1ahypoxia inducible factor 1, alpha subunit0.392
Foxa2forkhead box A20.380
Tbx2T-box 20.361
Trp63transformation related protein 630.315
Kitkit oncogene0.308
Nr3c1nuclear receptor subfamily 3, group C, member 10.290
Lmx1bLIM homeobox transcription factor 1 beta0.277
Gata6GATA binding protein 60.267
Axin1axin 10.261
Tbrachyury0.256
Lmx1aLIM homeobox transcription factor 1 alpha0.255
Nr2f2nuclear receptor subfamily 2, group F, member 20.254
Prkacaprotein kinase, cAMP dependent, catalytic, alpha0.254
Hmx3H6 homeobox 30.253
Chrdchordin0.253
Dll4delta-like 4 (Drosophila)0.251
Prrx1paired related homeobox 10.247
Cdx2caudal type homeobox 20.244
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.242
Nr5a1nuclear receptor subfamily 5, group A, member 10.239
Fgf15fibroblast growth factor 150.237
Pou3f3POU domain, class 3, transcription factor 30.235
Leprleptin receptor0.234
Egfrepidermal growth factor receptor0.234
Shesrc homology 2 domain-containing transforming protein E0.227
Gja1gap junction protein, alpha 10.225
Meox2mesenchyme homeobox 20.224
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.216
Col13a1collagen, type XIII, alpha 10.214
Otx2orthodenticle homolog 2 (Drosophila)0.212
Vegfavascular endothelial growth factor A0.211
Foxf1aforkhead box F1a0.211
Rarbretinoic acid receptor, beta0.206
Foxg1forkhead box G10.203
Pcsk5proprotein convertase subtilisin/kexin type 50.203
Bmpr1abone morphogenetic protein receptor, type 1A0.201
Adra2badrenergic receptor, alpha 2b0.199
Pcdh12protocadherin 120.186
Foxf2forkhead box F20.186
Axin2axin20.183
Acvrl1activin A receptor, type II-like 10.183
Bmp5bone morphogenetic protein 50.179
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism