The network for 'coumarin metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

coumarin metabolic process

The chemical reactions and pathways involving coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids.

NameDescriptionProbabilityFunc Analog Organism
Cyp2b1cytochrome P450, family 2, subfamily b, polypeptide 10.863
Ugt2b5UDP glucuronosyltransferase 2 family, polypeptide B50.765
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.665
Cyp1a1cytochrome P450, family 1, subfamily a, polypeptide 10.280
Kmokynurenine 3-monooxygenase (kynurenine 3-hydroxylase)0.247
Gsta5glutathione S-transferase Yc2 subunit0.219
Cyp4a10cytochrome P450, family 4, subfamily a, polypeptide 100.188
Sult1b1sulfotransferase family, cytosolic, 1B, member 10.174
Ugt2b1UDP glucuronosyltransferase 2 family, polypeptide B10.172
LOC100365112carboxylesterase-like0.160
Cyp3a18cytochrome P450, family 3, subfamily a, polypeptide 180.148
Dpysdihydropyrimidinase0.137
Sult1e1sulfotransferase family 1E, estrogen-preferring, member 10.102
Ugt1a6UDP glucuronosyltransferase 1 family, polypeptide A60.102
Cyp2d3cytochrome P450, family 2, subfamily d, polypeptide 30.094
Cyp3a2cytochrome P450, family 3, subfamily a, polypeptide 20.093
A1i3alpha-1-inhibitor III0.093
Otcornithine carbamoyltransferase0.085
Cyp2c13cytochrome P450, family 2, subfamily c, polypeptide 130.084
LOC293989cytochrome P450-like0.079
Ces1ccarboxylesterase 1C0.074
Cyp2a2cytochrome P450, family 2, subfamily a, polypeptide 20.073
Cyp2b2cytochrome P450, family 2, subfamily b, polypeptide 20.073
LOC494499LOC494499 protein0.072
Cyp2a1cytochrome P450, family 2, subfamily a, polypeptide 10.063
Gsta2glutathione S-transferase A20.061
Cyp4f1cytochrome P450, family 4, subfamily f, polypeptide 10.058
Crygfcrystallin, gamma F0.052
Sult1c3sulfotransferase family, cytosolic, 1C, member 30.048
Slc23a1solute carrier family 23 (nucleobase transporters), member 10.045
Cyp2b3cytochrome P450, family 2, subfamily b, polypeptide 30.044
Cyp4a8cytochrome P450, family 4, subfamily a, polypeptide 80.042
Cyp2d4cytochrome P450, family 2, subfamily d, polypeptide 40.041
Cyp2d2cytochrome P450, family 2, subfamily d, polypeptide 20.041
Apobapolipoprotein B0.038
Cyp3a23/3a1cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 10.037
Cyp2f4cytochrome P450, family 2, subfamily f, polypeptide 40.036
Sult1c2sulfotransferase family, cytosolic, 1C, member 20.036
Ces1ecarboxylesterase 1E0.035
Mgst2microsomal glutathione S-transferase 20.029
Abcc2ATP-binding cassette, subfamily C (CFTR/MRP), member 20.029
Haao3-hydroxyanthranilate 3,4-dioxygenase0.028
Ugt1a1UDP glucuronosyltransferase 1 family, polypeptide A10.026
LOC100361547Cytochrome P450, family 2, subfamily c, polypeptide 7-like0.026
Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 20.026
Ugt1a7cUDP glucuronosyltransferase 1 family, polypeptide A7C0.023
Cyp4a2cytochrome P450, family 4, subfamily a, polypeptide 20.023
LOC100361864UDP-glucuronosyltransferase 2B3-like0.023
Azgp1alpha-2-glycoprotein 1, zinc-binding0.022
Cyp3a9cytochrome P450, family 3, subfamily a, polypeptide 90.021
Mbl2mannose-binding lectin (protein C) 20.021
Ugt2b37UDP-glucuronosyltransferase 2 family, member 370.019
Fabp1fatty acid binding protein 1, liver0.017
Cyp2c22cytochrome P450, family 2, subfamily c, polypeptide 220.016
Sult2a1sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 10.015
Sult2al1sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 10.015
Pigrpolymeric immunoglobulin receptor0.014
Galnt5UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)0.014
L3mbtl3l(3)mbt-like 3 (Drosophila)0.014
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.013
Slc22a7solute carrier family 22 (organic anion transporter), member 70.013
Apoa2apolipoprotein A-II0.011
Adh1alcohol dehydrogenase 1 (class I)0.010
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CYP2A6cytochrome P450, family 2, subfamily A, polypeptide 61.000
CYP2C9cytochrome P450, family 2, subfamily C, polypeptide 90.952
CYP2B6cytochrome P450, family 2, subfamily B, polypeptide 60.835
CYP2C19cytochrome P450, family 2, subfamily C, polypeptide 190.826
ACRV1acrosomal vesicle protein 10.799
CYP4A11cytochrome P450, family 4, subfamily A, polypeptide 110.749
CYP2A7cytochrome P450, family 2, subfamily A, polypeptide 70.609
CYP2C18cytochrome P450, family 2, subfamily C, polypeptide 180.297
CYP2D6cytochrome P450, family 2, subfamily D, polypeptide 60.255
ADH6alcohol dehydrogenase 6 (class V)0.213
CYP3A4cytochrome P450, family 3, subfamily A, polypeptide 40.188
LAMC3laminin, gamma 30.152
NAT2N-acetyltransferase 2 (arylamine N-acetyltransferase)0.139
C8Bcomplement component 8, beta polypeptide0.128
C6complement component 60.104
ITIH4inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)0.099
CYP4F12cytochrome P450, family 4, subfamily F, polypeptide 120.070
GLYATglycine-N-acyltransferase0.068
FMO4flavin containing monooxygenase 40.067
DAOD-amino-acid oxidase0.065
AADACarylacetamide deacetylase (esterase)0.063
SULT1B1sulfotransferase family, cytosolic, 1B, member 10.061
CYP3A43cytochrome P450, family 3, subfamily A, polypeptide 430.061
HRGhistidine-rich glycoprotein0.059
GPLD1glycosylphosphatidylinositol specific phospholipase D10.058
OTCornithine carbamoyltransferase0.053
A1CFAPOBEC1 complementation factor0.053
HMGCS23-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)0.052
MAT1Amethionine adenosyltransferase I, alpha0.049
CFHR4complement factor H-related 40.048
CYP4F2cytochrome P450, family 4, subfamily F, polypeptide 20.045
ALDOBaldolase B, fructose-bisphosphate0.044
C4BPAcomplement component 4 binding protein, alpha0.040
F9coagulation factor IX0.040
CYP1A2cytochrome P450, family 1, subfamily A, polypeptide 20.039
PZPpregnancy-zone protein0.035
SLC10A1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.035
HABP2hyaluronan binding protein 20.034
PFKFB16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 10.031
FETUBfetuin B0.031
SLC5A5solute carrier family 5 (sodium iodide symporter), member 50.030
GSTA3glutathione S-transferase alpha 30.030
MAST1microtubule associated serine/threonine kinase 10.030
TMPRSS6transmembrane protease, serine 60.029
ENTPD5ectonucleoside triphosphate diphosphohydrolase 50.027
HPXhemopexin0.027
C8Acomplement component 8, alpha polypeptide0.025
CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 10.024
APCSamyloid P component, serum0.024
SLC22A1solute carrier family 22 (organic cation transporter), member 10.023
CYP3A5cytochrome P450, family 3, subfamily A, polypeptide 50.023
AGXT2alanine--glyoxylate aminotransferase 20.023
ABCC2ATP-binding cassette, sub-family C (CFTR/MRP), member 20.023
GBA3glucosidase, beta, acid 3 (cytosolic)0.023
MTTPmicrosomal triglyceride transfer protein0.022
GATMglycine amidinotransferase (L-arginine:glycine amidinotransferase)0.021
HAAO3-hydroxyanthranilate 3,4-dioxygenase0.021
CYP2C8cytochrome P450, family 2, subfamily C, polypeptide 80.020
RNF32ring finger protein 320.020
SLC1A2solute carrier family 1 (glial high affinity glutamate transporter), member 20.019
DNASE1L3deoxyribonuclease I-like 30.019
XDHxanthine dehydrogenase0.018
AFMafamin0.018
GYS2glycogen synthase 2 (liver)0.018
FGL1fibrinogen-like 10.018
SLC2A2solute carrier family 2 (facilitated glucose transporter), member 20.018
F13Bcoagulation factor XIII, B polypeptide0.018
F11coagulation factor XI0.017
BHMTbetaine--homocysteine S-methyltransferase0.017
SULT2A1sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 10.017
CYP4F3cytochrome P450, family 4, subfamily F, polypeptide 30.017
PON1paraoxonase 10.017
ITIH2inter-alpha (globulin) inhibitor H20.017
CYP3A7cytochrome P450, family 3, subfamily A, polypeptide 70.017
SLC28A1solute carrier family 28 (sodium-coupled nucleoside transporter), member 10.016
LPAlipoprotein, Lp(a)0.016
CYP7A1cytochrome P450, family 7, subfamily A, polypeptide 10.016
PLA2G10phospholipase A2, group X0.016
TTPAtocopherol (alpha) transfer protein0.016
CRPC-reactive protein, pentraxin-related0.015
SERPINC1serpin peptidase inhibitor, clade C (antithrombin), member 10.015
GCKRglucokinase (hexokinase 4) regulator0.015
AKR1C4aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)0.014
APOC3apolipoprotein C-III0.014
FGGfibrinogen gamma chain0.014
CYP2J2cytochrome P450, family 2, subfamily J, polypeptide 20.014
SLCO1A2solute carrier organic anion transporter family, member 1A20.014
UGT2B15UDP glucuronosyltransferase 2 family, polypeptide B150.013
NR1H4nuclear receptor subfamily 1, group H, member 40.013
MTHFRmethylenetetrahydrofolate reductase (NAD(P)H)0.013
MEP1Bmeprin A, beta0.013
UGT1A3UDP glucuronosyltransferase 1 family, polypeptide A30.013
CNGA1cyclic nucleotide gated channel alpha 10.012
CYP4F11cytochrome P450, family 4, subfamily F, polypeptide 110.012
RAB3DRAB3D, member RAS oncogene family0.012
SERPINA6serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 60.012
A2Malpha-2-macroglobulin0.012
COLEC10collectin sub-family member 10 (C-type lectin)0.012
UGT1A1UDP glucuronosyltransferase 1 family, polypeptide A10.012
CPB2carboxypeptidase B2 (plasma)0.012
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism