The network for 'norepinephrine metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

norepinephrine metabolic process

The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.

NameDescriptionProbabilityFunc Analog Organism
Psmb5proteasome (prosome, macropain) subunit, beta type 50.533
Tuba1ctubulin, alpha 1C0.055
Oaz1ornithine decarboxylase antizyme 10.047
Gstp1glutathione S-transferase pi 10.045
Ppp1caprotein phosphatase 1, catalytic subunit, alpha isoform0.045
Lgals3lectin, galactoside-binding, soluble, 30.045
Pgam1phosphoglycerate mutase 1 (brain)0.043
Gpx4glutathione peroxidase 40.039
Ghrgrowth hormone receptor0.039
Fmo2flavin containing monooxygenase 20.036
Slc35b1solute carrier family 35, member B10.031
Ppiapeptidylprolyl isomerase A (cyclophilin A)0.030
Rpn1ribophorin I0.029
Pbldphenazine biosynthesis-like protein domain containing0.028
S100a11S100 calcium binding protein A11 (calizzarin)0.028
Cox4i1cytochrome c oxidase subunit IV isoform 10.027
Calm1calmodulin 10.026
Slco1a1solute carrier organic anion transporter family, member 1a10.026
Sult2al1sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 10.025
Il15interleukin 150.025
Cyp3a18cytochrome P450, family 3, subfamily a, polypeptide 180.024
Slc17a1solute carrier family 17 (sodium phosphate), member 10.024
Dapk3death-associated protein kinase 30.023
Nqo1NAD(P)H dehydrogenase, quinone 10.023
Mtus1mitochondrial tumor suppressor 10.022
Flt1FMS-related tyrosine kinase 10.022
Slc23a1solute carrier family 23 (nucleobase transporters), member 10.021
Aldh6a1aldehyde dehydrogenase 6 family, member A10.020
Kmokynurenine 3-monooxygenase (kynurenine 3-hydroxylase)0.020
Olr1701olfactory receptor 17010.020
Anxa2annexin A20.019
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.019
Dpm2dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit0.018
G6pdglucose-6-phosphate dehydrogenase0.018
Akr1c12aldo-keto reductase family 1, member C120.018
Akr1c14aldo-keto reductase family 1, member C140.018
As3mtarsenic (+3 oxidation state) methyltransferase0.018
Bphlbiphenyl hydrolase-like (serine hydrolase)0.018
Nr0b2nuclear receptor subfamily 0, group B, member 20.018
Mgst2microsomal glutathione S-transferase 20.017
Vom2r52vomeronasal 2 receptor, 520.017
Gstm2glutathione S-transferase mu 20.017
Serpina3mserine (or cysteine) proteinase inhibitor, clade A, member 3M0.016
Copz1coatomer protein complex, subunit zeta 10.016
Ptgfrprostaglandin F receptor0.016
Tac1tachykinin 10.016
Olr1469olfactory receptor Olr14690.015
Rplp2ribosomal protein, large P20.015
Bcl2l1Bcl2-like 10.015
Ddr1discoidin domain receptor tyrosine kinase 10.015
Mdh1malate dehydrogenase 1, NAD (soluble)0.015
Actg1actin, gamma 10.015
Il1r1interleukin 1 receptor, type I0.015
Slco2b1solute carrier organic anion transporter family, member 2b10.014
Fgfr3fibroblast growth factor receptor 30.014
Cyp2d3cytochrome P450, family 2, subfamily d, polypeptide 30.014
Atxn10ataxin 100.014
P2ry4pyrimidinergic receptor P2Y, G-protein coupled, 40.014
Slc17a3solute carrier family 17 (sodium phosphate), member 30.014
Akp3alkaline phosphatase 3, intestine, not Mn requiring0.013
Ube2fubiquitin-conjugating enzyme E2F (putative)0.013
Hint3histidine triad nucleotide binding protein 30.013
Kif16bkinesin family member 16B0.013
Cyp3a23/3a1cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 10.013
Obp3alpha-2u globulin PGCL40.013
RGD1562987similar to cDNA sequence BC0311810.013
Mup5major urinary protein 50.013
Atp6v0cATPase, H+ transporting, lysosomal V0 subunit C0.013
Thrbthyroid hormone receptor beta0.013
Gabrpgamma-aminobutyric acid (GABA-A) receptor, pi0.012
Cd36CD36 molecule (thrombospondin receptor)0.012
Mosc1MOCO sulphurase C-terminal domain containing 10.012
Pi4k2aphosphatidylinositol 4-kinase type 2 alpha0.012
RGD1309501hypothetical LOC3055520.012
Pygmphosphorylase, glycogen, muscle0.012
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.012
Colqcollagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase0.012
Cyp4f1cytochrome P450, family 4, subfamily f, polypeptide 10.012
Mbpmyelin basic protein0.012
Acox2acyl-Coenzyme A oxidase 2, branched chain0.012
Lgals9lectin, galactoside-binding, soluble, 90.012
A1bgalpha-1-B glycoprotein0.012
Tmem66transmembrane protein 660.011
Ergv-ets erythroblastosis virus E26 oncogene homolog (avian)0.011
Mocs2molybdenum cofactor synthesis 20.011
Ftlferritin, light polypeptide0.011
Cyp2j3cytochrome P450, family 2, subfamily j, polypeptide 30.011
Fabp12fatty acid binding protein 120.011
Chgachromogranin A0.011
Aqp9aquaporin 90.011
Taldo1transaldolase 10.011
Top3atopoisomerase (DNA) III alpha0.011
Hsd17b4hydroxysteroid (17-beta) dehydrogenase 40.011
Hibch3-hydroxyisobutyryl-Coenzyme A hydrolase0.011
CrpC-reactive protein, pentraxin-related0.011
Prdx2peroxiredoxin 20.011
Itpr2inositol 1,4,5-triphosphate receptor, type 20.011
LOC100360501ribonuclease inhibitor-like0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ZNF746zinc finger protein 7460.264
PDZD11PDZ domain containing 110.182
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.086
ARNTaryl hydrocarbon receptor nuclear translocator0.059
EGLN1egl nine homolog 1 (C. elegans)0.056
VHLvon Hippel-Lindau tumor suppressor0.025
PRMT2protein arginine methyltransferase 20.024
EGLN3egl nine homolog 3 (C. elegans)0.020
PINK1PTEN induced putative kinase 10.018
DEDDdeath effector domain containing0.013
SKILSKI-like oncogene0.012
MEF2Cmyocyte enhancer factor 2C0.012
ZFYVE9zinc finger, FYVE domain containing 90.011
PDCD2programmed cell death 20.011
FBXO7F-box protein 70.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.496
Neurod1neurogenic differentiation 10.399
Isl1ISL1 transcription factor, LIM/homeodomain0.265
Ascl1achaete-scute complex homolog 1 (Drosophila)0.183
Pitx2paired-like homeodomain transcription factor 20.107
Neurod4neurogenic differentiation 40.099
Lhx3LIM homeobox protein 30.098
Onecut1one cut domain, family member 10.077
Nos3nitric oxide synthase 3, endothelial cell0.066
Gata1GATA binding protein 10.062
Neurog3neurogenin 30.062
Gata4GATA binding protein 40.059
Ptf1apancreas specific transcription factor, 1a0.050
Notch1Notch gene homolog 1 (Drosophila)0.049
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.049
Zfpm2zinc finger protein, multitype 20.043
Vegfavascular endothelial growth factor A0.038
Nr3c1nuclear receptor subfamily 3, group C, member 10.037
Pdx1pancreatic and duodenal homeobox 10.037
MecomMDS1 and EVI1 complex locus0.035
Gpr50G-protein-coupled receptor 500.035
Neurog2neurogenin 20.035
Shhsonic hedgehog0.034
Nkx2-2NK2 transcription factor related, locus 2 (Drosophila)0.034
Egln1EGL nine homolog 1 (C. elegans)0.032
Pitx1paired-like homeodomain transcription factor 10.031
Egfrepidermal growth factor receptor0.031
Eporerythropoietin receptor0.031
Nhlh1nescient helix loop helix 10.030
Tal1T-cell acute lymphocytic leukemia 10.029
Vhlvon Hippel-Lindau tumor suppressor0.028
Tgfbr2transforming growth factor, beta receptor II0.028
Srrm4serine/arginine repetitive matrix 40.027
Hey2hairy/enhancer-of-split related with YRPW motif 20.026
Ptpn11protein tyrosine phosphatase, non-receptor type 110.026
Kcnj5potassium inwardly-rectifying channel, subfamily J, member 50.025
Ntf3neurotrophin 30.025
Tbx5T-box 50.025
Rdh10retinol dehydrogenase 10 (all-trans)0.024
Gp9glycoprotein 9 (platelet)0.022
Nkx1-2NK1 transcription factor related, locus 2 (Drosophila)0.021
Kcnq1potassium voltage-gated channel, subfamily Q, member 10.021
Sim2single-minded homolog 2 (Drosophila)0.021
En1engrailed 10.021
Hand2heart and neural crest derivatives expressed transcript 20.021
Rxraretinoid X receptor alpha0.020
Hba-xhemoglobin X, alpha-like embryonic chain in Hba complex0.020
Hoxa1homeobox A10.020
Pax6paired box gene 60.019
Tgfb2transforming growth factor, beta 20.019
Fshrfollicle stimulating hormone receptor0.019
Pou3f2POU domain, class 3, transcription factor 20.019
Lhx5LIM homeobox protein 50.019
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.018
Dab1disabled homolog 1 (Drosophila)0.018
Jag1jagged 10.018
Pax3paired box gene 30.017
Foxf1aforkhead box F1a0.017
Tbx20T-box 200.016
Msx1homeobox, msh-like 10.016
Prox1prospero-related homeobox 10.016
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.016
Ldb3LIM domain binding 30.016
Nkx6-1NK6 homeobox 10.015
Mesp1mesoderm posterior 10.015
Gja1gap junction protein, alpha 10.015
Fgf8fibroblast growth factor 80.015
Pou4f3POU domain, class 4, transcription factor 30.015
Klf3Kruppel-like factor 3 (basic)0.015
Acvr1activin A receptor, type 10.014
Fbn1fibrillin 10.014
Hand1heart and neural crest derivatives expressed transcript 10.014
Cbfa2t3core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)0.014
Otx2orthodenticle homolog 2 (Drosophila)0.013
Atp7bATPase, Cu++ transporting, beta polypeptide0.013
Fgf6fibroblast growth factor 60.013
Scn5asodium channel, voltage-gated, type V, alpha0.013
Amhanti-Mullerian hormone0.012
Ebf3early B-cell factor 30.012
Lmx1bLIM homeobox transcription factor 1 beta0.012
Hoxa13homeobox A130.012
Gata6GATA binding protein 60.012
Lmo2LIM domain only 20.012
Adam17a disintegrin and metallopeptidase domain 170.012
Rb1retinoblastoma 10.012
Emx1empty spiracles homolog 1 (Drosophila)0.012
Slc31a1solute carrier family 31, member 10.012
Cyp19a1cytochrome P450, family 19, subfamily a, polypeptide 10.012
Crygccrystallin, gamma C0.012
Lhcgrluteinizing hormone/choriogonadotropin receptor0.011
Gnrhrgonadotropin releasing hormone receptor0.011
Tbx3T-box 30.011
Shox2short stature homeobox 20.011
Ank1ankyrin 1, erythroid0.011
Kiss1KiSS-1 metastasis-suppressor0.011
Dccdeleted in colorectal carcinoma0.011
Evx2even skipped homeotic gene 2 homolog0.011
Gata5GATA binding protein 50.011
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism