The network for 'regulation of nuclear cell cycle dna replication' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of nuclear cell cycle dna replication

Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.

NameDescriptionProbabilityFunc Analog Organism
Top2atopoisomerase (DNA) II alpha0.204
Syt4synaptotagmin IV0.056
Mcm6minichromosome maintenance complex component 60.047
Prkacbprotein kinase, cAMP dependent, catalytic, beta0.034
Spc25SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.028
Cks2CDC28 protein kinase regulatory subunit 20.021
Ube2cubiquitin-conjugating enzyme E2C0.021
Ccnb1cyclin B10.019
NsfN-ethylmaleimide-sensitive factor0.018
Pttg1pituitary tumor-transforming 10.017
Racgap1Rac GTPase-activating protein 10.015
Vegfavascular endothelial growth factor A0.014
SnrkSNF related kinase0.013
PbkPDZ binding kinase0.012
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.012
Ppp3r1protein phosphatase 3, regulatory subunit B, alpha isoform0.012
Cdkn3cyclin-dependent kinase inhibitor 30.011
Cdca3cell division cycle associated 30.011
Mcm5minichromosome maintenance complex component 50.011
Rab24RAB24, member RAS oncogene family0.011
JunJun oncogene0.011
Ns5atp9NS5A (hepatitis C virus) transactivated protein 90.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
YY1YY1 transcription factor0.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Mapk14mitogen-activated protein kinase 141.000
Mapk11mitogen-activated protein kinase 110.992
Atf2activating transcription factor 20.991
Trp53transformation related protein 530.964
Ccne1cyclin E10.915
Mapk8ip3mitogen-activated protein kinase 8 interacting protein 30.861
Ccna2cyclin A20.800
Smc1astructural maintenance of chromosomes 1A0.755
Mapk8mitogen-activated protein kinase 80.725
Mapkapk2MAP kinase-activated protein kinase 20.703
Prc1protein regulator of cytokinesis 10.572
Mcm2minichromosome maintenance deficient 2 mitotin (S. cerevisiae)0.552
Cdk4cyclin-dependent kinase 40.538
Mecp2methyl CpG binding protein 20.343
Cdc6cell division cycle 6 homolog (S. cerevisiae)0.328
Mapk9mitogen-activated protein kinase 90.287
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.279
Smc3structural maintenace of chromosomes 30.245
Ptenphosphatase and tensin homolog0.228
Mknk2MAP kinase-interacting serine/threonine kinase 20.189
Klc1kinesin light chain 10.173
Ccnb1cyclin B10.160
Mtmr1myotubularin related protein 10.160
Ncaphnon-SMC condensin I complex, subunit H0.152
Mcm3minichromosome maintenance deficient 3 (S. cerevisiae)0.138
Elavl1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.138
Cdk2cyclin-dependent kinase 20.132
Ccnd1cyclin D10.131
Mybl2myeloblastosis oncogene-like 20.118
Tcf19transcription factor 190.117
Cdca7lcell division cycle associated 7 like0.105
Orc1origin recognition complex, subunit 10.104
Brca2breast cancer 20.098
Msh2mutS homolog 2 (E. coli)0.094
Cdca5cell division cycle associated 50.090
Plk1polo-like kinase 1 (Drosophila)0.089
Prkceprotein kinase C, epsilon0.087
Ccnfcyclin F0.086
Dna2DNA replication helicase 2 homolog (yeast)0.086
Ccnb2cyclin B20.070
WwoxWW domain-containing oxidoreductase0.068
Mknk1MAP kinase-interacting serine/threonine kinase 10.067
Mcm5minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)0.064
E2f1E2F transcription factor 10.063
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.059
Top2atopoisomerase (DNA) II alpha0.059
Aurkbaurora kinase B0.058
Cdca8cell division cycle associated 80.057
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.056
Wdhd1WD repeat and HMG-box DNA binding protein 10.055
Aurkaaurora kinase A0.053
Mapkbp1mitogen-activated protein kinase binding protein 10.052
Cdca7cell division cycle associated 70.049
H1histocompatibility 10.048
Fam48afamily with sequence similarity 48, member A0.047
Zfp445zinc finger protein 4450.046
Kif22kinesin family member 220.046
Nek2NIMA (never in mitosis gene a)-related expressed kinase 20.046
Cenpacentromere protein A0.046
Dtldenticleless homolog (Drosophila)0.044
Pole2polymerase (DNA directed), epsilon 2 (p59 subunit)0.043
E2f8E2F transcription factor 80.043
Cdc45cell division cycle 45 homolog (S. cerevisiae)0.042
Kif11kinesin family member 110.042
Hist1h1ahistone cluster 1, H1a0.041
Cdkn1bcyclin-dependent kinase inhibitor 1B0.040
Uhrf1ubiquitin-like, containing PHD and RING finger domains, 10.038
Brca1breast cancer 10.037
Mcm7minichromosome maintenance deficient 7 (S. cerevisiae)0.037
Metmet proto-oncogene0.037
Ints7integrator complex subunit 70.036
Pms2postmeiotic segregation increased 2 (S. cerevisiae)0.036
Sp1trans-acting transcription factor 10.036
Mib1mindbomb homolog 1 (Drosophila)0.035
GnptabN-acetylglucosamine-1-phosphate transferase, alpha and beta subunits0.034
Ube2tubiquitin-conjugating enzyme E2T (putative)0.032
Atmataxia telangiectasia mutated homolog (human)0.031
Racgap1Rac GTPase-activating protein 10.030
WrnWerner syndrome homolog (human)0.030
Birc5baculoviral IAP repeat-containing 50.030
Mphosph9M-phase phosphoprotein 90.030
Rad51ap1RAD51 associated protein 10.029
Cops7bCOP9 (constitutive photomorphogenic) homolog, subunit 7b (Arabidopsis thaliana)0.028
Ddx46DEAD (Asp-Glu-Ala-Asp) box polypeptide 460.028
Stk39serine/threonine kinase 39, STE20/SPS1 homolog (yeast)0.027
Hmmrhyaluronan mediated motility receptor (RHAMM)0.027
Llgl1lethal giant larvae homolog 1 (Drosophila)0.027
Chaf1bchromatin assembly factor 1, subunit B (p60)0.027
Mapk1mitogen-activated protein kinase 10.027
Pold1polymerase (DNA directed), delta 1, catalytic subunit0.026
Smarcd1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 10.026
Mlh1mutL homolog 1 (E. coli)0.026
Mdm2transformed mouse 3T3 cell double minute 20.025
Kif4kinesin family member 40.025
Unguracil DNA glycosylase0.025
Iqgap3IQ motif containing GTPase activating protein 30.024
RfngRFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase0.024
Ate1arginyltransferase 10.023
Map2k7mitogen-activated protein kinase kinase 70.022
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism