The network for 'prepulse inhibition' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

prepulse inhibition

The process in which a startle magnitude is reduced when the startling stimulus is preceded by a low-intensity prepulse.

NameDescriptionProbabilityFunc Analog Organism
Adora2aadenosine A2a receptor0.821
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.424
Drd1adopamine receptor D1A0.338
Mylk2myosin light chain kinase 20.288
Shox2short stature homeobox 20.277
Syn1synapsin I0.266
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.214
Grm6glutamate receptor, metabotropic 60.154
Cd3gCD3 molecule, gamma0.126
Ghrhrgrowth hormone releasing hormone receptor0.105
Grm7glutamate receptor, metabotropic 70.100
Pfkfb26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 20.094
Ins2insulin 20.080
Trhr2thyrotropin releasing hormone receptor 20.077
Nmbrneuromedin B receptor0.074
Adora1adenosine A1 receptor0.074
Ms4a2membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)0.070
Grin2aglutamate receptor, ionotropic, N-methyl D-aspartate 2A0.068
Apba1amyloid beta (A4) precursor protein-binding, family A, member 10.067
Dlgap3discs, large (Drosophila) homolog-associated protein 30.067
Arpp21cAMP-regulated phosphoprotein 210.066
Hpcal4hippocalcin-like 40.062
Chrm4cholinergic receptor, muscarinic 40.062
Prkcgprotein kinase C, gamma0.061
Sema6bsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B0.060
Grprgastrin releasing peptide receptor0.060
Opn1mwopsin 1 (cone pigments), medium-wave-sensitive0.060
Kcnq3potassium voltage-gated channel, KQT-like subfamily, member 30.060
Slc18a3solute carrier family 18 (vesicular acetylcholine), member 30.054
Dlg4discs, large homolog 4 (Drosophila)0.052
Myt1lmyelin transcription factor 1-like0.051
Gng7guanine nucleotide binding protein (G protein), gamma 70.051
Ephb1Eph receptor B10.050
Lin7blin-7 homolog b (C. elegans)0.050
Atxn1ataxin 10.046
Itgamintegrin, alpha M0.045
Cckbrcholecystokinin B receptor0.043
Atp2b3ATPase, Ca++ transporting, plasma membrane 30.043
Glp1rglucagon-like peptide 1 receptor0.042
Prol1proline rich, lacrimal 10.040
Tacr1tachykinin receptor 10.040
Pfkfb46-phosphofructo-2-kinase/fructose-2,6-biphosphatase 40.039
Sptbn2spectrin, beta, non-erythrocytic 20.038
Avpr1barginine vasopressin receptor 1B0.037
Ppp1r9bprotein phosphatase 1, regulatory subunit 9B0.037
Cacna1gcalcium channel, voltage-dependent, T type, alpha 1G subunit0.036
Avparginine vasopressin0.035
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.035
Ptch1patched homolog 1 (Drosophila)0.034
Cacnb1calcium channel, voltage-dependent, beta 1 subunit0.034
Crhr1corticotropin releasing hormone receptor 10.034
Rgs9regulator of G-protein signaling 90.034
Hrkharakiri, BCL2 interacting protein (contains only BH3 domain)0.033
Srcv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.033
Kcna3potassium voltage-gated channel, shaker-related subfamily, member 30.033
Grm8glutamate receptor, metabotropic 80.033
Cntn3contactin 3 (plasmacytoma associated)0.033
Gnrhrgonadotropin releasing hormone receptor0.032
Fgf2fibroblast growth factor 20.032
Lhcgrluteinizing hormone/choriogonadotropin receptor0.031
Gabrr2gamma-aminobutyric acid (GABA) receptor, rho 20.031
Art2ADP-ribosyltransferase 20.031
Vom2r53vomeronasal 2 receptor, 530.031
Gzmkgranzyme K0.030
Gzmbgranzyme B0.030
Pcdhb12protocadherin beta 120.029
Syt5synaptotagmin V0.029
Oprk1opioid receptor, kappa 10.029
Unc5bunc-5 homolog B (C. elegans)0.029
Egr4early growth response 40.029
Pcsk4proprotein convertase subtilisin/kexin type 40.028
St8sia3ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 30.028
Olr1696olfactory receptor 16960.028
Olr226olfactory receptor 2260.028
Madcam1mucosal vascular addressin cell adhesion molecule 10.027
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.027
Slc14a2solute carrier family 14 (urea transporter), member 20.027
Magmyelin-associated glycoprotein0.027
Drd2dopamine receptor D20.027
Chrm3cholinergic receptor, muscarinic 30.027
Padi2peptidyl arginine deiminase, type II0.026
Csdc2cold shock domain containing C2, RNA binding0.026
Oprm1opioid receptor, mu 10.026
Ptafrplatelet-activating factor receptor0.026
Accn2amiloride-sensitive cation channel 2, neuronal0.025
St8sia1ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 10.025
Gipgastric inhibitory polypeptide0.025
Begainbrain-enriched guanylate kinase-associated0.025
Il8rbinterleukin 8 receptor, beta0.025
Gnalguanine nucleotide binding protein, alpha stimulating, olfactory type0.025
Igf2insulin-like growth factor 20.025
Crisp2cysteine-rich secretory protein 20.024
Halhistidine ammonia lyase0.024
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
DVL3dishevelled, dsh homolog 3 (Drosophila)0.166
MAGI3membrane associated guanylate kinase, WW and PDZ domain containing 30.095
PPP1R9Bprotein phosphatase 1, regulatory (inhibitor) subunit 9B0.086
SLC6A3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.041
NAMPTnicotinamide phosphoribosyltransferase0.013
CAV1caveolin 1, caveolae protein, 22kDa0.010
MYO16myosin XVI0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.997
Nrxn1neurexin I0.688
Dlg4discs, large homolog 4 (Drosophila)0.488
Nrxn3neurexin III0.307
Cbln1cerebellin 1 precursor protein0.232
Vangl1vang-like 1 (van gogh, Drosophila)0.226
Drd2dopamine receptor D20.215
Nrxn2neurexin II0.157
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)0.141
Vangl2vang-like 2 (van gogh, Drosophila)0.104
Unc79unc-79 homolog (C. elegans)0.082
Ctnnb1catenin (cadherin associated protein), beta 10.079
Slc18a2solute carrier family 18 (vesicular monoamine), member 20.057
Shc3src homology 2 domain-containing transforming protein C30.050
Gria2glutamate receptor, ionotropic, AMPA2 (alpha 2)0.033
Emx1empty spiracles homolog 1 (Drosophila)0.021
Numbnumb gene homolog (Drosophila)0.020
Calb2calbindin 20.020
Sncasynuclein, alpha0.019
InadlInaD-like (Drosophila)0.018
Msi1Musashi homolog 1(Drosophila)0.018
Ppargperoxisome proliferator activated receptor gamma0.017
Drd1adopamine receptor D1A0.016
Smurf2SMAD specific E3 ubiquitin protein ligase 20.015
Grid2glutamate receptor, ionotropic, delta 20.014
SrcRous sarcoma oncogene0.014
Gabra5gamma-aminobutyric acid (GABA) A receptor, subunit alpha 50.014
Shdsrc homology 2 domain-containing transforming protein D0.014
Pick1protein interacting with C kinase 10.014
Efna2ephrin A20.013
Mageb3melanoma antigen, family B, 30.013
Klk6kallikrein related-peptidase 60.012
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.012
Cd36CD36 antigen0.012
Dlgap1discs, large (Drosophila) homolog-associated protein 10.012
Edn2endothelin 20.012
Srcin1SRC kinase signaling inhibitor 10.012
Gabrb3gamma-aminobutyric acid (GABA) A receptor, subunit beta 30.012
Sema5bsema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B0.012
Slc1a6solute carrier family 1 (high affinity aspartate/glutamate transporter), member 60.012
Pdlim5PDZ and LIM domain 50.011
Anks1bankyrin repeat and sterile alpha motif domain containing 1B0.011
Lratlecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)0.011
Nrcamneuron-glia-CAM-related cell adhesion molecule0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism