The network for 'response to vitamin' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to vitamin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.

NameDescriptionProbabilityFunc Analog Organism
Ephx1epoxide hydrolase 1, microsomal0.859
Col3a1collagen, type III, alpha 10.460
Dnase1l3deoxyribonuclease 1-like 30.393
Mgst1microsomal glutathione S-transferase 10.392
Gstm2glutathione S-transferase mu 20.380
Cd44Cd44 molecule0.376
Gja5gap junction protein, alpha 50.343
Col1a1collagen, type I, alpha 10.320
Ptgs2prostaglandin-endoperoxide synthase 20.320
Mgst2microsomal glutathione S-transferase 20.308
Gsta3glutathione S-transferase A30.303
Serpine1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.301
Gstt1glutathione S-transferase theta 10.297
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.296
Fn1fibronectin 10.282
Ccl2chemokine (C-C motif) ligand 20.278
Serpina4serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 40.263
Apcsamyloid P component, serum0.254
Ces1ccarboxylesterase 1C0.253
Igfalsinsulin-like growth factor binding protein, acid labile subunit0.248
Cd14CD14 molecule0.243
Neurl3neuralized homolog 3 (Drosophila)0.241
Fabp1fatty acid binding protein 1, liver0.239
Hsd17b2hydroxysteroid (17-beta) dehydrogenase 20.235
C5ar1complement component 5a receptor 10.219
LOC305103cell surface glycoprotein gp420.219
Pla2g2aphospholipase A2, group IIA (platelets, synovial fluid)0.201
Ptprhprotein tyrosine phosphatase, receptor type, H0.197
Foxd3forkhead box D30.193
Stc1stanniocalcin 10.192
Dab2disabled homolog 2 (Drosophila)0.188
Ccl4chemokine (C-C motif) ligand 40.178
Selpselectin P0.177
Dmgdhdimethylglycine dehydrogenase0.175
Clcn5chloride channel 50.171
Tnftumor necrosis factor (TNF superfamily, member 2)0.171
Cybbcytochrome b-245, beta polypeptide0.170
Cps1carbamoyl-phosphate synthetase 10.167
Ankrd1ankyrin repeat domain 1 (cardiac muscle)0.163
Fat2FAT tumor suppressor homolog 2 (Drosophila)0.162
Fapfibroblast activation protein, alpha0.159
Serpinh1serine (or cysteine) peptidase inhibitor, clade H, member 10.159
Sftpdsurfactant protein D0.157
Lgals1lectin, galactoside-binding, soluble, 10.157
Cdc42bpbCDC42 binding protein kinase beta (DMPK-like)0.156
Pzppregnancy-zone protein0.155
Kcne1potassium voltage-gated channel, Isk-related family, member 10.154
Gpx2glutathione peroxidase 20.153
Cyp3a2cytochrome P450, family 3, subfamily a, polypeptide 20.153
Ppardperoxisome proliferator-activated receptor delta0.152
Dmbt1deleted in malignant brain tumors 10.150
Haao3-hydroxyanthranilate 3,4-dioxygenase0.149
Sult1e1sulfotransferase family 1E, estrogen-preferring, member 10.145
Arl11ADP-ribosylation factor-like 110.144
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.143
Bcl2B-cell CLL/lymphoma 20.140
A1i3alpha-1-inhibitor III0.139
Ccl20chemokine (C-C motif) ligand 200.139
Il1binterleukin 1 beta0.139
Anxa5annexin A50.138
Mmp3matrix metallopeptidase 30.137
Hsd17b3hydroxysteroid (17-beta) dehydrogenase 30.137
Mmp12matrix metallopeptidase 120.137
Loxlysyl oxidase0.137
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.136
Rararetinoic acid receptor, alpha0.136
Nlrp6NLR family, pyrin domain containing 60.135
Mosc2MOCO sulphurase C-terminal domain containing 20.135
Ccnd3cyclin D30.133
Igfbp5insulin-like growth factor binding protein 50.132
Sult2a1sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 10.132
Hspb1heat shock protein 10.131
Sult1a1sulfotransferase family, cytosolic, 1A, phenol-preferring, member 10.129
Fcn1ficolin (collagen/fibrinogen domain containing) 10.129
Znf503zinc finger protein 5030.128
Cltcclathrin, heavy chain (Hc)0.126
Ripk3receptor-interacting serine-threonine kinase 30.125
Foxd1forkhead box D10.125
Mef2dmyocyte enhancer factor 2D0.124
Smad7SMAD family member 70.122
Rbp2retinol binding protein 2, cellular0.121
Serpina3nserine (or cysteine) peptidase inhibitor, clade A, member 3N0.121
Tattyrosine aminotransferase0.120
Mmp2matrix metallopeptidase 20.120
Gulogulonolactone (L-) oxidase0.120
Spp1secreted phosphoprotein 10.119
Apoa5apolipoprotein A-V0.119
Col8a1collagen, type VIII, alpha 10.119
Cyp4f4cytochrome P450, family 4, subfamily f, polypeptide 40.118
DdtD-dopachrome tautomerase0.118
Serpina11serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 110.117
Il1r2interleukin 1 receptor, type II0.115
Stat6signal transducer and activator of transcription 60.114
Il6interleukin 60.113
Postnperiostin, osteoblast specific factor0.112
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.112
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
ptger2aprostaglandin E receptor 2a (subtype EP2)0.903
col1a1acollagen, type I, alpha 1a0.689
col1a2collagen, type I, alpha 20.663
ptgs2aprostaglandin-endoperoxide synthase 2a0.585
fabp11afatty acid binding protein 11a0.518
itgb1bintegrin, beta 1b0.476
ppargperoxisome proliferator activated receptor gamma0.428
cebpaCCAAT/enhancer binding protein (C/EBP), alpha0.417
fgfrl1afibroblast growth factor receptor-like 1a0.395
rbp4retinol binding protein 4, plasma0.388
lmnalamin A0.369
id1inhibitor of DNA binding 10.350
tgfbitransforming growth factor, beta-induced0.344
sox9aSRY-box containing gene 9a0.314
mstnamyostatin a0.307
prrx1apaired related homeobox 1a0.295
col5a1procollagen, type V, alpha 10.284
col5a2lcollagen, type V, alpha 2-like0.271
itgb1aintegrin, beta 1a0.256
rargaretinoic acid receptor gamma a0.238
aqp1a.1aquaporin 1a, tandem duplicate 10.236
tp53bp2tumor protein p53 binding protein, 20.230
crabp1bcellular retinoic acid binding protein 1b0.217
crabp2acellular retinoic acid binding protein 2, a0.216
lpar1lysophosphatidic acid receptor 10.210
dctdopachrome tautomerase0.209
rbp7bretinol binding protein 7b, cellular0.202
osr1odd-skipped related 1 (Drosophila)0.201
kiss1KiSS-1 metastasis-suppressor0.188
cyp51cytochrome P450, family 510.182
il17rdinterleukin 17 receptor D0.176
insrbinsulin receptor b0.176
neo1neogenin 10.174
fabp3fatty acid binding protein 3, muscle and heart0.168
postnperiostin, osteoblast specific factor0.160
inhbaainhibin, beta Aa0.160
vdravitamin D receptor a0.160
cx30.3connexin 30.30.158
aldh1a2aldehyde dehydrogenase 1 family, member A20.153
ptgs1prostaglandin-endoperoxide synthase 10.150
dlx4adistal-less homeobox gene 4a0.145
ca2carbonic anhydrase II0.144
nog3noggin 30.140
bnc1basonuclin 10.137
brd2bbromodomain containing 2b0.132
mtpmicrosomal triglyceride transfer protein0.129
apoebapolipoprotein Eb0.129
hsp47heat shock protein 470.129
pmp22aperipheral myelin protein 22a0.128
pck1phosphoenolpyruvate carboxykinase 1 (soluble)0.125
itgb1b.1integrin, beta 1b.10.122
trpv6transient receptor potential cation channel, subfamily V, member 60.121
tmprss4atransmembrane protease, serine 4a0.120
m17IL-6 subfamily cytokine M170.119
mmp14amatrix metalloproteinase 14a (membrane-inserted)0.118
aqp12aquaporin 120.118
mbnl1muscleblind-like (Drosophila)0.115
hnf4ahepatocyte nuclear factor 4, alpha0.113
tgfbr2transforming growth factor, beta receptor II0.113
mst1macrophage stimulating 1 (hepatocyte growth factor-like)0.112
cbr1lcarbonyl reductase 1-like0.109
bmp2bbone morphogenetic protein 2b0.108
duoxdual oxidase0.107
sult2st2sulfotransferase family 2, cytosolic sulfotransferase 20.104
fabp10afatty acid binding protein 10a, liver basic0.102
lfnglunatic fringe homolog0.102
col7a1lcollagen type VII alpha 1-like0.100
gdf11growth differentiation factor 110.098
egfraepidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)0.098
slc2a10solute carrier family 2 (facilitated glucose transporter), member 100.097
col1a1bcollagen, type I, alpha 1b0.097
fzd5frizzled homolog 50.095
pdgfrlplatelet-derived growth factor receptor-like0.094
mdkamidkine-related growth factor0.093
rargbretinoic acid receptor, gamma b0.093
ptgdsprostaglandin D2 synthase0.093
bmpr1bbbone morphogenetic protein receptor, type 1bb0.093
casrlcalcium-sensing receptor, like0.093
ucp1uncoupling protein 10.090
slc2a1bsolute carrier family 2 (facilitated glucose transporter), member 1b0.090
tyrp1btyrosinase-related protein 1b0.090
col6a3collagen, type VI, alpha 30.089
hmgb1bhigh-mobility group box 1b0.089
col10a1collagen, type X, alpha 10.089
erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog0.089
mcoln1mucolipin 10.088
gamtguanidinoacetate N-methyltransferase0.088
bmp4bone morphogenetic protein 40.087
bcl2l1bcl2-like 10.085
slc26a3solute carrier family 26, member 30.084
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CDK6cyclin-dependent kinase 60.571
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.161
THBS1thrombospondin 10.157
NCOR2nuclear receptor corepressor 20.157
RXRAretinoid X receptor, alpha0.148
ACACBacetyl-CoA carboxylase beta0.109
NRP1neuropilin 10.094
DNMT3BDNA (cytosine-5-)-methyltransferase 3 beta0.094
UHRF1ubiquitin-like with PHD and ring finger domains 10.089
RARAretinoic acid receptor, alpha0.085
CCND3cyclin D30.056
SETDB1SET domain, bifurcated 10.040
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.033
MED25mediator complex subunit 250.031
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.030
COL1A1collagen, type I, alpha 10.030
TEKTEK tyrosine kinase, endothelial0.030
HNF4Ahepatocyte nuclear factor 4, alpha0.026
VAC14Vac14 homolog (S. cerevisiae)0.026
AXLAXL receptor tyrosine kinase0.025
IL8interleukin 80.024
CCR5chemokine (C-C motif) receptor 50.024
IL1R1interleukin 1 receptor, type I0.024
EZH2enhancer of zeste homolog 2 (Drosophila)0.023
WNT3Awingless-type MMTV integration site family, member 3A0.022
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.021
IRS1insulin receptor substrate 10.020
VDRvitamin D (1,25- dihydroxyvitamin D3) receptor0.019
SUZ12suppressor of zeste 12 homolog (Drosophila)0.019
AGTR2angiotensin II receptor, type 20.019
FADS2fatty acid desaturase 20.018
DHCR77-dehydrocholesterol reductase0.018
SMC1Astructural maintenance of chromosomes 1A0.017
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.017
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.016
TNFAIP6tumor necrosis factor, alpha-induced protein 60.016
SCDstearoyl-CoA desaturase (delta-9-desaturase)0.016
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.016
ARHGEF12Rho guanine nucleotide exchange factor (GEF) 120.016
NRIP1nuclear receptor interacting protein 10.016
DNMT3ADNA (cytosine-5-)-methyltransferase 3 alpha0.015
CCL20chemokine (C-C motif) ligand 200.015
ICAM1intercellular adhesion molecule 10.015
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.015
COL1A2collagen, type I, alpha 20.015
HDAC1histone deacetylase 10.015
CCND1cyclin D10.014
COL4A1collagen, type IV, alpha 10.014
COL5A1collagen, type V, alpha 10.014
COL3A1collagen, type III, alpha 10.014
ESR1estrogen receptor 10.014
PLAURplasminogen activator, urokinase receptor0.013
CXCL11chemokine (C-X-C motif) ligand 110.013
MMP1matrix metallopeptidase 1 (interstitial collagenase)0.012
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.012
ARHGEF40Rho guanine nucleotide exchange factor (GEF) 400.012
HRhairless homolog (mouse)0.012
ANGPT2angiopoietin 20.012
CCL2chemokine (C-C motif) ligand 20.012
LRRK2leucine-rich repeat kinase 20.011
STC1stanniocalcin 10.011
IGFBP3insulin-like growth factor binding protein 30.011
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.011
PPARAperoxisome proliferator-activated receptor alpha0.011
CCNE1cyclin E10.011
DKK1dickkopf homolog 1 (Xenopus laevis)0.011
IL6interleukin 6 (interferon, beta 2)0.011
JAK2Janus kinase 20.010
ESR2estrogen receptor 2 (ER beta)0.010
FN1fibronectin 10.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Vdrvitamin D receptor0.881
Apoeapolipoprotein E0.543
Nos3nitric oxide synthase 3, endothelial cell0.537
Wnt5awingless-related MMTV integration site 5A0.304
Col1a1collagen, type I, alpha 10.210
Cav1caveolin 1, caveolae protein0.202
Leprleptin receptor0.196
Ren1renin 1 structural0.165
Bglapbone gamma carboxyglutamate protein0.152
Esr1estrogen receptor 1 (alpha)0.133
Fgfr2fibroblast growth factor receptor 20.129
Cdkn1bcyclin-dependent kinase inhibitor 1B0.127
Egfrepidermal growth factor receptor0.101
Cdk2cyclin-dependent kinase 20.092
Nos2nitric oxide synthase 2, inducible0.068
Ptpn11protein tyrosine phosphatase, non-receptor type 110.052
Ppargperoxisome proliferator activated receptor gamma0.046
Slc12a1solute carrier family 12, member 10.042
Apcadenomatosis polyposis coli0.042
Ghrgrowth hormone receptor0.041
Fgfr1fibroblast growth factor receptor 10.040
Vegfavascular endothelial growth factor A0.029
Ccl2chemokine (C-C motif) ligand 20.027
Bmp4bone morphogenetic protein 40.026
Thrathyroid hormone receptor alpha0.025
Notch2Notch gene homolog 2 (Drosophila)0.023
Ifnginterferon gamma0.023
Jag1jagged 10.023
Cyp19a1cytochrome P450, family 19, subfamily a, polypeptide 10.022
Ece1endothelin converting enzyme 10.021
Fgf23fibroblast growth factor 230.021
Nos1nitric oxide synthase 1, neuronal0.020
Arandrogen receptor0.019
Sfrp2secreted frizzled-related protein 20.019
Pkd1polycystic kidney disease 1 homolog0.019
Mapk8ip1mitogen-activated protein kinase 8 interacting protein 10.019
Cbx5chromobox homolog 5 (Drosophila HP1a)0.019
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.018
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.018
Stat3signal transducer and activator of transcription 30.018
Fam20cfamily with sequence similarity 20, member C0.018
Serpinh1serine (or cysteine) peptidase inhibitor, clade H, member 10.017
Tlr4toll-like receptor 40.017
C3complement component 30.017
Rbp1retinol binding protein 1, cellular0.017
Cdk4cyclin-dependent kinase 40.017
Phexphosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)0.016
Smad3MAD homolog 3 (Drosophila)0.016
Fstl1follistatin-like 10.015
Csf1colony stimulating factor 1 (macrophage)0.015
Ccr2chemokine (C-C motif) receptor 20.014
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.014
Insrinsulin receptor0.014
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.014
Ptgs2prostaglandin-endoperoxide synthase 20.014
Klf15Kruppel-like factor 150.013
Nr1h4nuclear receptor subfamily 1, group H, member 40.012
Agtr1aangiotensin II receptor, type 1a0.012
Spp1secreted phosphoprotein 10.012
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.012
Grb10growth factor receptor bound protein 100.012
Hif1ahypoxia inducible factor 1, alpha subunit0.012
Mep1ameprin 1 alpha0.011
Serping1serine (or cysteine) peptidase inhibitor, clade G, member 10.011
Sox4SRY-box containing gene 40.011
Il1r1interleukin 1 receptor, type I0.010
Ldlrlow density lipoprotein receptor0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism