The network for 'regulation of transcription regulatory region dna binding' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of transcription regulatory region dna binding

Any process that modulates the frequency, rate or extent of transcription regulatory region DNA binding.

NameDescriptionProbabilityFunc Analog Organism
Sox18SRY (sex determining region Y)-box 180.100
Acot12acyl-CoA thioesterase 120.092
Rpl22l1ribosomal protein L22 like 10.082
Gpr116G protein-coupled receptor 1160.076
Cdh5cadherin 50.075
Foxe1forkhead box E1 (thyroid transcription factor 2)0.074
Sox7SRY (sex determining region Y)-box 70.073
RanRAN, member RAS oncogene family0.053
Epn1Epsin 10.053
Il1r1interleukin 1 receptor, type I0.051
Nos3nitric oxide synthase 3, endothelial cell0.046
Edn2endothelin 20.042
Fgf1fibroblast growth factor 10.041
P2ry4pyrimidinergic receptor P2Y, G-protein coupled, 40.035
Ptprhprotein tyrosine phosphatase, receptor type, H0.033
DaoD-amino-acid oxidase0.032
Crybb1crystallin, beta B10.031
Gata2GATA binding protein 20.030
Cyp4f1cytochrome P450, family 4, subfamily f, polypeptide 10.029
Cyp4f4cytochrome P450, family 4, subfamily f, polypeptide 40.029
Tcfe2atranscription factor E2a0.028
Olr59olfactory receptor 590.028
Psmd12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.028
Foxe3forkhead box E30.027
Acox2acyl-Coenzyme A oxidase 2, branched chain0.026
Prlrprolactin receptor0.026
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.025
Actr10actin-related protein 10 homolog (S. cerevisiae)0.024
Ppp1r3bprotein phosphatase 1, regulatory (inhibitor) subunit 3B0.024
Acox3acyl-Coenzyme A oxidase 3, pristanoyl0.023
Ncaph2non-SMC condensin II complex, subunit H20.022
Acacbacetyl-Coenzyme A carboxylase beta0.022
Psbpc1prostatic steroid binding protein C10.022
Akp3alkaline phosphatase 3, intestine, not Mn requiring0.022
Ralgdsral guanine nucleotide dissociation stimulator0.022
Aqp2aquaporin 2 (collecting duct)0.022
Thrbthyroid hormone receptor beta0.022
Pparaperoxisome proliferator activated receptor alpha0.022
Fkbp3FK506 binding protein 30.022
Arhgef15Rho guanine nucleotide exchange factor (GEF) 150.021
Hsd17b6hydroxysteroid (17-beta) dehydrogenase 60.021
Tp53tumor protein p530.021
Gabrr1gamma-aminobutyric acid (GABA) receptor, rho 10.021
Oaz3ornithine decarboxylase antizyme 30.021
Slc9a4solute carrier family 9 (sodium/hydrogen exchanger), member 40.021
Foxd3forkhead box D30.020
Mef2dmyocyte enhancer factor 2D0.020
Dhdpsldihydrodipicolinate synthase-like, mitochondrial0.020
Epas1endothelial PAS domain protein 10.020
Slc26a1solute carrier family 26 (sulfate transporter), member 10.020
Neu3sialidase 3 (membrane sialidase)0.019
Cyp3a18cytochrome P450, family 3, subfamily a, polypeptide 180.019
Eif1ayeukaryotic translation initiation factor 1A, Y-linked0.019
Tpothyroid peroxidase0.019
Tpcn1two pore segment channel 10.018
Pax6paired box 60.018
Klf9Kruppel-like factor 90.018
Gucy2eguanylate cyclase 2E0.018
Hipk3homeodomain interacting protein kinase 30.018
Hes5hairy and enhancer of split 5 (Drosophila)0.018
Aspgasparaginase homolog (S. cerevisiae)0.018
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.017
Capn1calpain 10.017
Ppil3peptidylprolyl isomerase (cyclophilin)-like 30.017
Gulogulonolactone (L-) oxidase0.017
Slc9a3solute carrier family 9 (sodium/hydrogen exchanger), member 30.017
Wasf2WAS protein family, member 20.016
Safbscaffold attachment factor B0.016
Pyypeptide YY (mapped)0.016
Adrb1adrenergic, beta-1-, receptor0.016
Hnf4ahepatocyte nuclear factor 4, alpha0.016
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.016
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.016
Pvrl4poliovirus receptor-related 40.016
Pou3f2POU class 3 homeobox 20.016
Cdacytidine deaminase0.016
Elavl4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)0.016
Cyyr1cysteine/tyrosine-rich 10.016
Prkcgprotein kinase C, gamma0.015
Svs1seminal vesicle secretory protein 10.015
Tceb1transcription elongation factor B (SIII), polypeptide 10.015
Gcgrglucagon receptor0.015
Trib1tribbles homolog 1 (Drosophila)0.015
Apoa5apolipoprotein A-V0.015
Sdcbp2syndecan binding protein (syntenin) 20.015
Nlrp6NLR family, pyrin domain containing 60.015
Rtcd1RNA terminal phosphate cyclase domain 10.015
Naaladl1N-acetylated alpha-linked acidic dipeptidase-like 10.015
Fcer2Fc fragment of IgE, low affinity II, receptor for (CD23)0.015
Gse1genetic suppressor element 10.015
Defb1defensin beta 10.015
Slc23a1solute carrier family 23 (nucleobase transporters), member 10.015
Lrg1leucine-rich alpha-2-glycoprotein 10.015
Myo10myosin X0.014
Lemd2LEM domain containing 20.014
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
ruvb-1Protein RUVB-10.019
F21D5.2Protein F21D5.20.019
ruvb-2Protein RUVB-20.014
ran-1Protein RAN-10.013
T02G5.12Protein T02G5.120.012
ZC155.4Protein ZC155.40.011
eif-3.IProtein EIF-3.I0.011
hke-4.1Protein HKE-4.10.011
tac-1Protein TAC-10.010
pri-2Protein PRI-20.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
RdlResistant to dieldrin0.055
cwoclockwork orange0.033
fasfaint sausage0.033
Plc21CPhospholipase C at 21C0.029
pdm2POU domain protein 20.025
blotbloated tubules0.024
CG12424CG12424 gene product from transcript CG12424-RC0.022
emsempty spiracles0.021
myoglianinCG1838 gene product from transcript CG1838-RD0.019
Elongin-CElongin C0.019
CG3776CG3776 gene product from transcript CG3776-RA0.018
Rpn2CG11888 gene product from transcript CG11888-RA0.017
PdfPigment-dispersing factor0.017
DatDopamine N acetyltransferase0.017
Pdp1PAR-domain protein 10.016
l(1)G0045lethal (1) G00450.016
reporeversed polarity0.015
EndoGIEndonuclease G inhibitor0.015
Bre1CG10542 gene product from transcript CG10542-RA0.014
Ilp5Insulin-like peptide 50.014
Adgf-AAdenosine deaminase-related growth factor A0.013
HLH54FCG5005 gene product from transcript CG5005-RA0.013
CG4857CG4857 gene product from transcript CG4857-RD0.012
HandCG18144 gene product from transcript CG18144-RA0.011
RagACG11968 gene product from transcript CG11968-RA0.010
l(2)k14505lethal (2) k145050.010
Jarid2CG3654 gene product from transcript CG3654-RD0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ZNF43zinc finger protein 430.970
TAL1T-cell acute lymphocytic leukemia 10.856
ZNF273zinc finger protein 2730.809
ZNF253zinc finger protein 2530.771
ZNF675zinc finger protein 6750.660
TRAF2TNF receptor-associated factor 20.495
SKILSKI-like oncogene0.415
SMAD3SMAD family member 30.341
ZNF85zinc finger protein 850.267
ZNF708zinc finger protein 7080.255
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.245
RIPK2receptor-interacting serine-threonine kinase 20.217
ZNF680zinc finger protein 6800.180
ZNF117zinc finger protein 1170.173
SETD8SET domain containing (lysine methyltransferase) 80.159
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.136
ZNF430zinc finger protein 4300.134
SMAD9SMAD family member 90.134
ZNF93zinc finger protein 930.124
ZNF254zinc finger protein 2540.123
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.119
HIST2H3Chistone cluster 2, H3c0.117
TNFRSF14tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)0.095
NCOR2nuclear receptor corepressor 20.093
ZMYND11zinc finger, MYND-type containing 110.088
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.087
MAFAv-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)0.083
TRAF3TNF receptor-associated factor 30.082
SMURF1SMAD specific E3 ubiquitin protein ligase 10.066
ZNF91zinc finger protein 910.066
MLLT6myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 60.058
PIAS4protein inhibitor of activated STAT, 40.053
GATA2GATA binding protein 20.050
CD40CD40 molecule, TNF receptor superfamily member 50.048
RBBP4retinoblastoma binding protein 40.036
ZNF512Bzinc finger protein 512B0.036
TGFBR1transforming growth factor, beta receptor 10.036
TNFRSF9tumor necrosis factor receptor superfamily, member 90.034
ZNF107zinc finger protein 1070.032
ZNF682zinc finger protein 6820.030
TRADDTNFRSF1A-associated via death domain0.029
ZNF92zinc finger protein 920.028
TBX5T-box 50.027
NUMBLnumb homolog (Drosophila)-like0.025
KLF13Kruppel-like factor 130.024
MLLT1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10.021
TRAF1TNF receptor-associated factor 10.021
BIRC3baculoviral IAP repeat containing 30.020
PSEN2presenilin 2 (Alzheimer disease 4)0.020
MSX1msh homeobox 10.019
HDAC1histone deacetylase 10.018
RUNX1runt-related transcription factor 10.017
MDFIMyoD family inhibitor0.015
ANXA7annexin A70.015
SOD1superoxide dismutase 1, soluble0.014
TRAF6TNF receptor-associated factor 60.014
PAPPApregnancy-associated plasma protein A, pappalysin 10.014
HAND2heart and neural crest derivatives expressed 20.013
CXXC5CXXC finger protein 50.013
MSX2msh homeobox 20.013
TRAF5TNF receptor-associated factor 50.013
CIAPIN1cytokine induced apoptosis inhibitor 10.013
ITGA2Bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)0.012
TNFRSF11Atumor necrosis factor receptor superfamily, member 11a, NFKB activator0.012
SMAD7SMAD family member 70.012
ING2inhibitor of growth family, member 20.011
HOXB9homeobox B90.010
UBQLN4ubiquilin 40.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Gata4GATA binding protein 40.943
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.721
Otx2orthodenticle homolog 2 (Drosophila)0.696
Pitx2paired-like homeodomain transcription factor 20.687
Per2period homolog 2 (Drosophila)0.622
Hand1heart and neural crest derivatives expressed transcript 10.581
Per1period homolog 1 (Drosophila)0.507
Cry2cryptochrome 2 (photolyase-like)0.300
Fgf8fibroblast growth factor 80.286
Pax2paired box gene 20.188
Gata6GATA binding protein 60.182
Lhx3LIM homeobox protein 30.172
Hand2heart and neural crest derivatives expressed transcript 20.171
Shhsonic hedgehog0.169
E2f1E2F transcription factor 10.120
Pax6paired box gene 60.101
Zfpm2zinc finger protein, multitype 20.098
Hey2hairy/enhancer-of-split related with YRPW motif 20.090
Emx2empty spiracles homolog 2 (Drosophila)0.073
Pou4f2POU domain, class 4, transcription factor 20.065
Hes5hairy and enhancer of split 5 (Drosophila)0.057
Lhx9LIM homeobox protein 90.057
Pax3paired box gene 30.056
Hdac1histone deacetylase 10.055
Tal1T-cell acute lymphocytic leukemia 10.055
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.054
Foxc2forkhead box C20.052
Lmx1aLIM homeobox transcription factor 1 alpha0.049
Isl1ISL1 transcription factor, LIM/homeodomain0.048
Ntf3neurotrophin 30.048
En2engrailed 20.048
Wt1Wilms tumor 1 homolog0.046
Msx1homeobox, msh-like 10.045
Lef1lymphoid enhancer binding factor 10.039
Tgfb2transforming growth factor, beta 20.036
Snai1snail homolog 1 (Drosophila)0.036
Emx1empty spiracles homolog 1 (Drosophila)0.036
En1engrailed 10.033
Neurog2neurogenin 20.032
Tbx3T-box 30.031
Insm1insulinoma-associated 10.031
Usp2ubiquitin specific peptidase 20.030
Jag1jagged 10.030
Bnc1basonuclin 10.029
Gbx2gastrulation brain homeobox 20.026
Ebf3early B-cell factor 30.026
Arntlaryl hydrocarbon receptor nuclear translocator-like0.025
Ascl1achaete-scute complex homolog 1 (Drosophila)0.025
Mab21l2mab-21-like 2 (C. elegans)0.025
Sox2SRY-box containing gene 20.024
Coro1bcoronin, actin binding protein 1B0.022
Tbx20T-box 200.019
Ptpn11protein tyrosine phosphatase, non-receptor type 110.018
Prox1prospero-related homeobox 10.018
0610031J06RikRIKEN cDNA 0610031J06 gene0.018
Gdnfglial cell line derived neurotrophic factor0.018
Socs1suppressor of cytokine signaling 10.017
Akr1a4aldo-keto reductase family 1, member A4 (aldehyde reductase)0.017
Inca1inhibitor of CDK, cyclin A1 interacting protein 10.016
Tefthyrotroph embryonic factor0.016
Pold1polymerase (DNA directed), delta 1, catalytic subunit0.016
Nr2e1nuclear receptor subfamily 2, group E, member 10.016
Foxn1forkhead box N10.016
Sox4SRY-box containing gene 40.015
Srrm4serine/arginine repetitive matrix 40.015
Ldb2LIM domain binding 20.015
Rxraretinoid X receptor alpha0.015
Rspo2R-spondin 2 homolog (Xenopus laevis)0.015
Foxf1aforkhead box F1a0.015
Nkx1-2NK1 transcription factor related, locus 2 (Drosophila)0.014
Ighmbp2immunoglobulin mu binding protein 20.014
Onecut1one cut domain, family member 10.013
Sox7SRY-box containing gene 70.013
Nr5a1nuclear receptor subfamily 5, group A, member 10.013
Ufc1ubiquitin-fold modifier conjugating enzyme 10.012
Eya1eyes absent 1 homolog (Drosophila)0.012
Hoxa11homeobox A110.012
Gnai2guanine nucleotide binding protein (G protein), alpha inhibiting 20.012
Chmp2achromatin modifying protein 2A0.012
Nos3nitric oxide synthase 3, endothelial cell0.012
Ptf1apancreas specific transcription factor, 1a0.012
Epha3Eph receptor A30.011
Slc12a5solute carrier family 12, member 50.011
Hoxc8homeobox C80.011
Dkk1dickkopf homolog 1 (Xenopus laevis)0.011
Klf3Kruppel-like factor 3 (basic)0.011
Rnh1ribonuclease/angiogenin inhibitor 10.010
Nhlh1nescient helix loop helix 10.010
Lhx1LIM homeobox protein 10.010
Dpysl4dihydropyrimidinase-like 40.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism