The network for 'metanephric tubule development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

metanephric tubule development

The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros.

NameDescriptionProbabilityFunc Analog Organism
Insig1insulin induced gene 10.522
Sc4molsterol-C4-methyl oxidase-like0.441
Sqlesqualene epoxidase0.420
Hmgcs13-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)0.383
Cyp51cytochrome P450, family 510.359
Idi1isopentenyl-diphosphate delta isomerase 10.242
Fdpsfarnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)0.199
AclyATP citrate lyase0.177
Fdft1farnesyl diphosphate farnesyl transferase 10.155
Tgfbr3transforming growth factor, beta receptor III0.112
Dhcr2424-dehydrocholesterol reductase0.105
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.088
Fasnfatty acid synthase0.078
Cd86CD86 molecule0.063
Cd4Cd4 molecule0.055
Sp110SP110 nuclear body protein0.052
Lsslanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)0.040
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.038
Mvdmevalonate (diphospho) decarboxylase0.032
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.032
Fh1fumarate hydratase 10.028
Htr5b5-hydroxytryptamine (serotonin) receptor 5B0.028
Cd80Cd80 molecule0.027
Nek9NIMA (never in mitosis gene a)- related kinase 90.027
Parp14poly (ADP-ribose) polymerase family, member 140.025
Suclg1succinate-CoA ligase, alpha subunit0.025
LOC100362108poly (ADP-ribose) polymerase family, member 100.025
Fgf16fibroblast growth factor 160.025
Acap1ArfGAP with coiled-coil, ankyrin repeat and PH domains 10.024
Stat1signal transducer and activator of transcription 10.024
Bcl2B-cell CLL/lymphoma 20.024
Rnf213ring finger protein 2130.023
Testintestin gene0.022
Dhcr77-dehydrocholesterol reductase0.021
Cd8aCD8a molecule0.021
Itpr2inositol 1,4,5-triphosphate receptor, type 20.021
Mtus1mitochondrial tumor suppressor 10.020
Iappislet amyloid polypeptide0.020
Prrx1paired related homeobox 10.019
Irf7interferon regulatory factor 70.019
Il2rbinterleukin 2 receptor, beta0.019
Atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle0.019
Kcnh4potassium voltage-gated channel, subfamily H (eag-related), member 40.019
Cpa3carboxypeptidase A3, mast cell0.018
Flt1FMS-related tyrosine kinase 10.018
Trhr2thyrotropin releasing hormone receptor 20.018
Htr65-hydroxytryptamine (serotonin) receptor 60.018
Il9rinterleukin 9 receptor0.018
Bckdhbbranched chain keto acid dehydrogenase E1, beta polypeptide0.018
Etfaelectron-transfer-flavoprotein, alpha polypeptide0.017
Ncr1natural cytotoxicity triggering receptor 10.017
Rararetinoic acid receptor, alpha0.017
Eif2ak2eukaryotic translation initiation factor 2-alpha kinase 20.017
Reg3gregenerating islet-derived 3 gamma0.017
Fam70bfamily with sequence similarity 70, member B0.017
Ifi35interferon-induced protein 350.016
Stat2signal transducer and activator of transcription 20.016
Wapwhey acidic protein0.016
Selpselectin P0.016
Ascl1achaete-scute complex homolog 1 (Drosophila)0.016
Olaholeoyl-ACP hydrolase0.015
Atp5f1ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B10.015
Hsd17b7hydroxysteroid (17-beta) dehydrogenase 70.015
Cd5Cd5 molecule0.015
St8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.015
NsdhlNAD(P) dependent steroid dehydrogenase-like0.015
Gna15guanine nucleotide binding protein, alpha 150.015
MefvMediterranean fever0.015
Pde6hphosphodiesterase 6H, cGMP-specific, cone, gamma0.015
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.015
Sellselectin L0.014
Nos3nitric oxide synthase 3, endothelial cell0.014
Trim5tripartite motif-containing 50.014
Etfdhelectron-transferring-flavoprotein dehydrogenase0.014
Adkadenosine kinase0.014
Ptpn1protein tyrosine phosphatase, non-receptor type 10.014
C3ar1complement component 3a receptor 10.014
Igtpinterferon gamma induced GTPase0.014
Aco2aconitase 2, mitochondrial0.014
Il6stinterleukin 6 signal transducer0.014
Sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.014
Aqp2aquaporin 2 (collecting duct)0.014
Mx1myxovirus (influenza virus) resistance 10.014
Ddx58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.014
Igh-6immunoglobulin heavy chain 60.014
Lim2lens intrinsic membrane protein 20.013
Irf9interferon regulatory factor 90.013
Sc5dlsterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like0.013
Akap4A kinase (PRKA) anchor protein 40.013
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.013
Fcnbficolin B0.013
Myl7myosin, light chain 7, regulatory0.013
Wisp2WNT1 inducible signaling pathway protein 20.013
Krt5keratin 50.013
Il3interleukin 30.013
Muc1mucin 1, cell surface associated0.013
Pmfbp1polyamine modulated factor 1 binding protein 10.013
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PKD2polycystic kidney disease 2 (autosomal dominant)0.926
NR4A1nuclear receptor subfamily 4, group A, member 10.900
PKD1polycystic kidney disease 1 (autosomal dominant)0.836
ACAA2acetyl-CoA acyltransferase 20.360
TRPV5transient receptor potential cation channel, subfamily V, member 50.298
NKX2-1NK2 homeobox 10.267
TRPC1transient receptor potential cation channel, subfamily C, member 10.113
AMOTL1angiomotin like 10.061
GJA1gap junction protein, alpha 1, 43kDa0.057
TJP1tight junction protein 1 (zona occludens 1)0.055
TJP2tight junction protein 2 (zona occludens 2)0.052
FAM110Afamily with sequence similarity 110, member A0.040
CSNK1Ecasein kinase 1, epsilon0.040
BBS1Bardet-Biedl syndrome 10.036
NPHP1nephronophthisis 1 (juvenile)0.035
BBS10Bardet-Biedl syndrome 100.031
CALD1caldesmon 10.030
DIAPH1diaphanous homolog 1 (Drosophila)0.030
BBS4Bardet-Biedl syndrome 40.028
TEAD1TEA domain family member 1 (SV40 transcriptional enhancer factor)0.028
LATS1LATS, large tumor suppressor, homolog 1 (Drosophila)0.027
PTPN14protein tyrosine phosphatase, non-receptor type 140.027
TEAD4TEA domain family member 40.026
CSF3Rcolony stimulating factor 3 receptor (granulocyte)0.025
IL8interleukin 80.025
KLF5Kruppel-like factor 5 (intestinal)0.024
AMOTL2angiomotin like 20.023
LIFRleukemia inhibitory factor receptor alpha0.022
IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor)0.021
CRIM1cysteine rich transmembrane BMP regulator 1 (chordin-like)0.021
TEAD3TEA domain family member 30.020
MCCmutated in colorectal cancers0.019
PARVAparvin, alpha0.018
FAM110Cfamily with sequence similarity 110, member C0.018
HDAC4histone deacetylase 40.017
LAMC1laminin, gamma 1 (formerly LAMB2)0.017
WNT7Awingless-type MMTV integration site family, member 7A0.017
DVL1dishevelled, dsh homolog 1 (Drosophila)0.016
INHBBinhibin, beta B0.016
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.015
TM4SF1transmembrane 4 L six family member 10.015
PLSCR4phospholipid scramblase 40.015
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit0.015
PAMpeptidylglycine alpha-amidating monooxygenase0.015
LAMB1laminin, beta 10.014
ACACAacetyl-CoA carboxylase alpha0.014
CLCF1cardiotrophin-like cytokine factor 10.014
AXIN1axin 10.014
LHFPlipoma HMGIC fusion partner0.013
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.013
POU3F1POU class 3 homeobox 10.013
ARHGAP29Rho GTPase activating protein 290.013
PER1period homolog 1 (Drosophila)0.013
FZD7frizzled homolog 7 (Drosophila)0.012
EFEMP1EGF containing fibulin-like extracellular matrix protein 10.012
FGF18fibroblast growth factor 180.012
NR5A1nuclear receptor subfamily 5, group A, member 10.012
RGS7regulator of G-protein signaling 70.012
FERMT2fermitin family member 20.012
GPRC5AG protein-coupled receptor, family C, group 5, member A0.012
SPSB1splA/ryanodine receptor domain and SOCS box containing 10.012
GFPT2glutamine-fructose-6-phosphate transaminase 20.012
JAM2junctional adhesion molecule 20.011
PLS3plastin 30.011
CYR61cysteine-rich, angiogenic inducer, 610.011
BHLHE23basic helix-loop-helix family, member e230.011
CDH16cadherin 16, KSP-cadherin0.011
MAPK8IP3mitogen-activated protein kinase 8 interacting protein 30.011
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.011
LHX1LIM homeobox 10.011
GNG12guanine nucleotide binding protein (G protein), gamma 120.011
FBN1fibrillin 10.011
SDC4syndecan 40.011
ALPLalkaline phosphatase, liver/bone/kidney0.011
TCF7L2transcription factor 7-like 2 (T-cell specific, HMG-box)0.010
RSPO1R-spondin homolog (Xenopus laevis)0.010
EMX1empty spiracles homeobox 10.010
FOXC1forkhead box C10.010
FAT1FAT tumor suppressor homolog 1 (Drosophila)0.010
OLIG2oligodendrocyte lineage transcription factor 20.010
IL1R2interleukin 1 receptor, type II0.010
CLDN1claudin 10.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Pax2paired box gene 21.000
Pax8paired box gene 81.000
Lhx1LIM homeobox protein 10.999
Emx2empty spiracles homolog 2 (Drosophila)0.998
Otx2orthodenticle homolog 2 (Drosophila)0.995
Fgfr2fibroblast growth factor receptor 20.993
Wt1Wilms tumor 1 homolog0.979
Nr5a1nuclear receptor subfamily 5, group A, member 10.976
Shhsonic hedgehog0.973
Bcl2B-cell leukemia/lymphoma 20.968
Lhx3LIM homeobox protein 30.966
Otx1orthodenticle homolog 1 (Drosophila)0.962
Gdnfglial cell line derived neurotrophic factor0.959
Rargretinoic acid receptor, gamma0.947
Gli3GLI-Kruppel family member GLI30.925
Fgf8fibroblast growth factor 80.906
Wnt4wingless-related MMTV integration site 40.886
Hes5hairy and enhancer of split 5 (Drosophila)0.874
Foxc1forkhead box C10.826
Hes1hairy and enhancer of split 1 (Drosophila)0.814
Nos3nitric oxide synthase 3, endothelial cell0.812
Retret proto-oncogene0.809
Esr1estrogen receptor 1 (alpha)0.802
Bmp4bone morphogenetic protein 40.775
Fgfr1fibroblast growth factor receptor 10.749
Lhx9LIM homeobox protein 90.731
Emx1empty spiracles homolog 1 (Drosophila)0.724
Ptenphosphatase and tensin homolog0.713
Isl1ISL1 transcription factor, LIM/homeodomain0.713
Pax3paired box gene 30.667
Amhr2anti-Mullerian hormone type 2 receptor0.643
Dkk1dickkopf homolog 1 (Xenopus laevis)0.625
Drd2dopamine receptor D20.612
Pax6paired box gene 60.602
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.594
Sox2SRY-box containing gene 20.558
Hoxd13homeobox D130.549
Meox2mesenchyme homeobox 20.534
Rararetinoic acid receptor, alpha0.501
Hoxa11homeobox A110.496
Arandrogen receptor0.479
Ctnnb1catenin (cadherin associated protein), beta 10.475
Wwtr1WW domain containing transcription regulator 10.473
Leprleptin receptor0.466
Lmx1bLIM homeobox transcription factor 1 beta0.462
Hand1heart and neural crest derivatives expressed transcript 10.451
Rarbretinoic acid receptor, beta0.446
Kiss1KiSS-1 metastasis-suppressor0.406
Gbx2gastrulation brain homeobox 20.395
Fgf10fibroblast growth factor 100.367
Vegfavascular endothelial growth factor A0.364
Ghrgrowth hormone receptor0.327
Smad6MAD homolog 6 (Drosophila)0.321
Wnt9bwingless-type MMTV integration site 9B0.305
Pou3f3POU domain, class 3, transcription factor 30.295
Wnt3awingless-related MMTV integration site 3A0.281
Hoxd11homeobox D110.270
Vax1ventral anterior homeobox containing gene 10.263
Sox17SRY-box containing gene 170.244
Cdx1caudal type homeobox 10.233
Tcfap2ctranscription factor AP-2, gamma0.230
Lef1lymphoid enhancer binding factor 10.230
Yap1yes-associated protein 10.226
Pitx2paired-like homeodomain transcription factor 20.216
Slc12a1solute carrier family 12, member 10.212
Ren1renin 1 structural0.206
Wnt6wingless-related MMTV integration site 60.206
Nr2f2nuclear receptor subfamily 2, group F, member 20.206
Alx4aristaless-like homeobox 40.205
Lhcgrluteinizing hormone/choriogonadotropin receptor0.201
Foxd2forkhead box D20.193
Sall3sal-like 3 (Drosophila)0.193
Tbx2T-box 20.189
Gdf11growth differentiation factor 110.180
Eya1eyes absent 1 homolog (Drosophila)0.176
Ror2receptor tyrosine kinase-like orphan receptor 20.171
Msx1homeobox, msh-like 10.170
Bicc1bicaudal C homolog 1 (Drosophila)0.167
Cyp26a1cytochrome P450, family 26, subfamily a, polypeptide 10.159
Chrm1cholinergic receptor, muscarinic 1, CNS0.150
Ascl1achaete-scute complex homolog 1 (Drosophila)0.140
Dlx5distal-less homeobox 50.137
Alx3aristaless-like homeobox 30.134
Tead3TEA domain family member 30.133
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.132
Lmx1aLIM homeobox transcription factor 1 alpha0.131
Fgf15fibroblast growth factor 150.123
Sox11SRY-box containing gene 110.122
Gas1growth arrest specific 10.121
Rbpjlrecombination signal binding protein for immunoglobulin kappa J region-like0.120
Hoxb7homeobox B70.120
Ptgs2prostaglandin-endoperoxide synthase 20.113
Lama5laminin, alpha 50.112
Atoh7atonal homolog 7 (Drosophila)0.110
Foxn1forkhead box N10.110
Cgaglycoprotein hormones, alpha subunit0.109
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism