The network for 'purine ribonucleotide catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

purine ribonucleotide catabolic process

The chemical reactions and pathways resulting in the breakdown of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.

NameDescriptionProbabilityFunc Analog Organism
Arl1ADP-ribosylation factor-like 10.863
Tpm4tropomyosin 40.627
Anxa2annexin A20.574
Lman1lectin, mannose-binding, 10.545
S100a10S100 calcium binding protein A100.506
Sumo1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)0.489
Acta2smooth muscle alpha-actin0.487
Atp5bATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.478
Stxbp1syntaxin binding protein 10.417
Cyth3cytohesin 30.413
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.406
Gria2glutamate receptor, ionotropic, AMPA 20.398
Gdi2GDP dissociation inhibitor 20.397
Pja2praja 2, RING-H2 motif containing0.392
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.332
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.327
Apcadenomatous polyposis coli0.306
Vimvimentin0.296
Ap2b1adaptor-related protein complex 2, beta 1 subunit0.280
Cdk7cyclin-dependent kinase 70.273
Arpc1bactin related protein 2/3 complex, subunit 1B0.271
Rab1RAB1, member RAS oncogene family0.267
Psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.264
Stxbp5syntaxin binding protein 5 (tomosyn)0.247
Utrnutrophin0.246
Hsph1heat shock 105/110 protein 10.244
Ola1Obg-like ATPase 10.234
Eif4a2eukaryotic translation initiation factor 4A, isoform 20.234
Ndrg4N-myc downstream regulated gene 40.232
Pdclphosducin-like0.232
Hk1hexokinase 10.231
Anxa1annexin A10.230
Pfn1profilin 10.226
Pcnxl3pecanex-like 3 (Drosophila)0.226
Amphamphiphysin0.225
Gng7guanine nucleotide binding protein (G protein), gamma 70.221
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.220
Scarb1scavenger receptor class B, member 10.218
Pik3r2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.213
Ppp2caprotein phosphatase 2, catalytic subunit, alpha isoform0.205
Zfp260zinc finger protein 2600.203
Pls3plastin 3 (T-isoform)0.199
Gabrg1gamma-aminobutyric acid (GABA) A receptor, gamma 10.198
Ctnnbl1catenin, beta like 10.195
Myo1dmyosin ID0.193
S100a6S100 calcium binding protein A60.191
S100a4S100 calcium-binding protein A40.187
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.187
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.181
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)0.181
Myo1bmyosin Ib0.179
Dlg3discs, large homolog 3 (Drosophila)0.174
Wipf3WAS/WASL interacting protein family, member 30.173
Ap2a1adaptor-related protein complex 2, alpha 1 subunit0.171
RGD1309543similar to 2310014H01Rik protein0.170
Mtpnmyotrophin0.163
Dnajb9DnaJ (Hsp40) homolog, subfamily B, member 90.163
Prkacbprotein kinase, cAMP dependent, catalytic, beta0.163
Capgcapping protein (actin filament), gelsolin-like0.161
Flt1FMS-related tyrosine kinase 10.159
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.158
Gabrb3gamma-aminobutyric acid (GABA) A receptor, beta 30.158
Syngr2synaptogyrin 20.157
Alcamactivated leukocyte cell adhesion molecule0.157
Arhgap9Rho GTPase activating protein 90.155
Lynx1Ly6/neurotoxin 10.154
Psma5proteasome (prosome, macropain) subunit, alpha type 50.153
Atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle0.151
Anxa4annexin A40.148
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.148
Dlgap3discs, large (Drosophila) homolog-associated protein 30.146
Fgfr1Fibroblast growth factor receptor 10.145
Dmddystrophin0.145
Smg5Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)0.145
Rgs4regulator of G-protein signaling 40.143
Lgals3lectin, galactoside-binding, soluble, 30.143
Nckap1NCK-associated protein 10.141
Shank2SH3 and multiple ankyrin repeat domains 20.140
Cyth1cytohesin 10.140
S100a11S100 calcium binding protein A11 (calizzarin)0.140
Rhoaras homolog gene family, member A0.139
Klf6Kruppel-like factor 60.138
Lcp2lymphocyte cytosolic protein 20.138
P2rx7purinergic receptor P2X, ligand-gated ion channel, 70.137
Dapk3death-associated protein kinase 30.136
Mapk8ip1mitogen-activated protein kinase 8 interacting protein 10.135
Klf4Kruppel-like factor 4 (gut)0.134
Dnaja4DnaJ (Hsp40) homolog, subfamily A, member 40.132
Mapk3mitogen activated protein kinase 30.132
Cskc-src tyrosine kinase0.131
Eif5eukaryotic translation initiation factor 50.131
Epas1endothelial PAS domain protein 10.131
Copb1coatomer protein complex, subunit beta 10.131
Cops7aCOP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)0.130
Akap1A kinase (PRKA) anchor protein 10.129
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.129
Arhgap25Rho GTPase activating protein 250.128
Jtbjumping translocation breakpoint0.126
Ripk3receptor-interacting serine-threonine kinase 30.125
Exoc5exocyst complex component 50.122
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
lin-5Protein LIN-50.715
goa-1Protein GOA-10.513
sem-5Protein SEM-50.420
D1081.8Protein D1081.80.358
gpr-2Protein GPR-20.341
CELE_F29C4.2Protein F29C4.20.309
etr-1Protein ETR-10.291
chc-1Protein CHC-10.241
F10C2.4Protein F10C2.40.239
let-60Protein LET-600.238
glp-1Protein GLP-10.227
B0495.2Protein B0495.20.222
abts-1Protein ABTS-10.218
knl-1Protein KNL-10.216
lin-45Protein LIN-450.211
pkg-1Protein PKG-10.199
F44E5.1Protein F44E5.10.198
gpr-1Protein GPR-10.195
hsp-16.2Protein HSP-16.20.194
unc-54Protein UNC-540.185
unc-45Protein UNC-450.183
CELE_F47G4.4Protein F47G4.40.183
rga-3Protein RGA-30.179
mpk-1Protein MPK-10.166
R04F11.2Protein R04F11.20.165
lfi-1Protein LFI-10.162
rgl-1Protein RGL-10.158
npp-9Protein NPP-90.156
miro-1Protein MIRO-10.151
nasp-2Protein NASP-20.149
CELE_Y47G6A.18Protein Y47G6A.180.148
pptr-2Protein PPTR-20.148
npp-5Protein NPP-50.139
hsp-16.48Protein HSP-16.480.135
mai-2Protein MAI-20.134
W05B5.1Protein W05B5.10.132
gpb-1Protein GPB-10.131
vab-10Protein VAB-100.131
cyc-1Protein CYC-10.130
mig-2Protein MIG-20.129
pdl-1Protein PDL-10.129
coh-3Protein COH-30.125
sma-6Protein SMA-60.125
C30G12.6Protein C30G12.60.124
C53C9.2Protein C53C9.20.124
rpt-4Protein RPT-40.123
T23F11.1Protein T23F11.10.122
F48A11.4Protein F48A11.40.122
F53A10.2Protein F53A10.20.121
ina-1Protein INA-10.120
bet-2Protein BET-20.119
crt-1Protein CRT-10.119
Y110A7A.4Protein Y110A7A.40.119
mus-81Protein MUS-810.117
snf-1Protein SNF-10.117
prp-8Protein PRP-80.116
F58F12.1Protein F58F12.10.115
kin-2Protein KIN-20.115
eef-1GProtein EEF-1G0.114
rab-5Protein RAB-50.113
mcm-2Protein MCM-20.113
fkb-6Protein FKB-60.111
dpm-1Protein DPM-10.110
R53.4Protein R53.40.109
gei-18Protein GEI-180.108
kcc-1Protein KCC-10.107
ret-1Protein RET-10.107
tag-341Protein TAG-3410.105
sav-1Protein SAV-10.104
CELE_W03F9.10Protein W03F9.100.099
T22C1.6Protein T22C1.60.099
hif-1Protein HIF-10.098
CELE_Y48A5A.1Protein Y48A5A.10.095
ubq-1Protein UBQ-10.094
lin-10Protein LIN-100.092
egrh-1Protein EGRH-10.091
F39H12.3Protein F39H12.30.091
csr-1Protein CSR-10.091
alx-1Protein ALX-10.090
rme-4Protein RME-40.090
unc-60Protein UNC-600.090
sec-24.1Protein SEC-24.10.090
bmk-1Protein BMK-10.089
cogc-8Protein COGC-80.089
afd-1Protein AFD-10.089
oct-2Protein OCT-20.088
ykt-6Protein YKT-60.088
cmd-1Protein CMD-10.087
ric-8Protein RIC-80.087
vha-3Protein VHA-30.087
eef-2Protein EEF-20.086
eef-1A.1Protein EEF-1A.10.086
pbrm-1Protein PBRM-10.086
CELE_F08D12.1Protein F08D12.10.086
D2085.5Protein D2085.50.086
egl-30Protein EGL-300.086
F41C3.4Protein F41C3.40.085
let-502Protein LET-5020.085
F28C6.4Protein F28C6.40.085
CELE_Y60A3A.9Protein Y60A3A.90.085
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
tpm4tropomyosin 40.085
atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.069
myhz2myosin, heavy polypeptide 2, fast muscle specific0.027
ndufs4NADH dehydrogenase (ubiquinone) Fe-S protein 4, (NADH-coenzyme Q reductase)0.025
bidaBH3 interacting domain death agonist0.022
copebcore promoter element binding protein0.019
gnai2lguanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like0.019
tnni2a.4troponin I, skeletal, fast 2a.40.018
efna1bephrin A1b0.018
zgc:100829zgc:1008290.017
hspa4aheat shock protein 4a0.016
rab25RAB25, member RAS oncogene family0.016
nf1aneurofibromin 1a0.015
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.015
myhz1.2myosin, heavy polypeptide 1.2, skeletal muscle0.014
rtcd1RNA terminal phosphate cyclase domain 10.014
arpc5aactin related protein 2/3 complex, subunit 5A0.014
tnnt3btroponin T3b, skeletal, fast0.014
plxnb2aplexin b2a0.013
nme2b.2non-metastatic cells 2b.2, protein (NM23B) expressed in0.013
acheacetylcholinesterase0.012
olfm2olfactomedin 20.012
ppargc1alperoxisome proliferator-activated receptor gamma, coactivator 1 alpha like0.012
lrp2low density lipoprotein-related protein 20.012
atp1a1a.4ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide0.011
zgc:111961zgc:1119610.011
hk1hexokinase 10.011
msnamoesin a0.011
atp1b1bATPase, Na+/K+ transporting, beta 1b polypeptide0.011
atp1a3aATPase, Na+/K+ transporting, alpha 3a polypeptide0.011
atp6v0caATPase, H+ transporting, lysosomal, V0 subunit c, a0.011
ppme1protein phosphatase methylesterase 10.010
gnl2guanine nucleotide binding protein-like 2 (nucleolar)0.010
gna14guanine nucleotide binding protein (G protein), alpha 140.010
cct5chaperonin containing TCP1, subunit 5 (epsilon)0.010
snap25bsynaptosome-associated protein 25b0.010
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Pi3K92ECG4141 gene product from transcript CG4141-RB0.992
Ras85DRas oncogene at 85D0.974
RhebCG1081 gene product from transcript CG1081-RA0.911
shishibire0.866
KhcKinesin heavy chain0.691
MoeMoesin0.686
Ced-12CG5336 gene product from transcript CG5336-RA0.656
zipzipper0.650
smidsmallminded0.645
tsrtwinstar0.624
armarmadillo0.605
Myo31DFMyosin 31DF0.587
mbcmyoblast city0.581
staustaufen0.581
PtenCG5671 gene product from transcript CG5671-RB0.566
tkvthickveins0.552
CG8155CG8155 gene product from transcript CG8155-RA0.549
pblpebble0.517
rokRho-kinase0.513
RhoGAP68FCG6811 gene product from transcript CG6811-RA0.503
sunstunted0.492
chicchickadee0.491
Uba1Ubiquitin activating enzyme 10.487
pod1CG4532 gene product from transcript CG4532-RF0.454
bazbazooka0.435
DlicDynein light intermediate chain0.434
jarjaguar0.434
EphEph receptor tyrosine kinase0.434
ninaEneither inactivation nor afterpotential E0.415
ninaCneither inactivation nor afterpotential C0.405
Stat92ESignal-transducer and activator of transcription protein at 92E0.395
TER94CG2331 gene product from transcript CG2331-RA0.392
mbtmushroom bodies tiny0.378
enaenabled0.376
MadMothers against dpp0.373
JraJun-related antigen0.370
rictorrapamycin-insensitive companion of Tor0.346
Snr1Snf5-related 10.343
RhoGEF2CG9635 gene product from transcript CG9635-RF0.334
sggshaggy0.324
SosSon of sevenless0.323
porinCG6647 gene product from transcript CG6647-RA0.317
trpltrp-like0.316
WASpCG1520 gene product from transcript CG1520-RA0.314
trptransient receptor potential0.301
G-oalpha47AG protein oalpha 47A0.299
drprdraper0.294
LanALaminin A0.286
ctaconcertina0.283
Rab5Rab-protein 50.267
Rac1CG2248 gene product from transcript CG2248-RA0.265
Rpd3CG7471 gene product from transcript CG7471-RA0.262
trioCG18214 gene product from transcript CG18214-RA0.260
NNotch0.258
Pk61CProtein kinase 61C0.257
AbiAbelson interacting protein0.254
kenken and barbie0.252
CG1344CG1344 gene product from transcript CG1344-RA0.247
Gyc-89DbGuanylyl cyclase at 89Db0.246
WnkCG7177 gene product from transcript CG7177-RA0.245
NaCP60ENa channel protein 60E0.243
nebnebbish0.239
CctgammaCG8977 gene product from transcript CG8977-RC0.238
EphrinCG1862 gene product from transcript CG1862-RA0.233
pucpuckered0.232
Trim9CG31721 gene product from transcript CG31721-RB0.230
wupAwings up A0.229
Rbsn-5Rabenosyn-50.225
Rab11Rab-protein 110.214
dltdiscs lost0.214
Rho1CG8416 gene product from transcript CG8416-RB0.209
Rab7Rab-protein 70.207
cenG1Acentaurin gamma 1A0.205
Tsc1CG6147 gene product from transcript CG6147-RA0.202
NmnatNicotinamide mononucleotide adenylyltransferase0.200
csulcapsuleen0.196
mei-9meiotic 90.196
sqhspaghetti squash0.195
Rab2Rab-protein 20.194
DAAMDishevelled Associated Activator of Morphogenesis0.191
AblAbl tyrosine kinase0.190
didumdilute class unconventional myosin0.187
Su(Tpl)CG32217 gene product from transcript CG32217-RB0.183
PakPAK-kinase0.182
CG32772CG32772 gene product from transcript CG32772-RC0.182
Arf79FADP ribosylation factor 79F0.180
ttktramtrack0.179
flwflapwing0.177
mysmyospheroid0.175
Rab6Rab-protein 60.175
inaCinactivation no afterpotential C0.175
Dhc64CDynein heavy chain 64C0.174
kibrakibra ortholog0.171
pxplexus0.170
Cdc42CG12530 gene product from transcript CG12530-RA0.168
waplwings apart-like0.167
wtswarts0.167
maskmultiple ankyrin repeats single KH domain0.166
tutlturtle0.166
Syx7Syntaxin 70.164
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)1.000
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)1.000
RAB5ARAB5A, member RAS oncogene family1.000
SH3KBP1SH3-domain kinase binding protein 10.998
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.997
OCRLoculocerebrorenal syndrome of Lowe0.996
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.996
ARRB2arrestin, beta 20.995
PTK2PTK2 protein tyrosine kinase 20.995
SNX9sorting nexin 90.994
DNM1dynamin 10.988
DNM2dynamin 20.988
ARRB1arrestin, beta 10.985
MTORmechanistic target of rapamycin (serine/threonine kinase)0.985
RAB1ARAB1A, member RAS oncogene family0.975
S100A6S100 calcium binding protein A60.974
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 10.974
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.973
FGFR2fibroblast growth factor receptor 20.973
TRIM63tripartite motif containing 630.963
ITSN1intersectin 1 (SH3 domain protein)0.961
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.960
SQSTM1sequestosome 10.959
EEA1early endosome antigen 10.954
SFNstratifin0.953
CDK7cyclin-dependent kinase 70.952
GRB2growth factor receptor-bound protein 20.949
THOC4THO complex 40.948
S100A8S100 calcium binding protein A80.945
ILKintegrin-linked kinase0.941
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.937
JUNjun proto-oncogene0.932
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.926
HSPA1Bheat shock 70kDa protein 1B0.918
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.917
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.916
ABI1abl-interactor 10.911
SEPT2septin 20.910
LAMTOR1late endosomal/lysosomal adaptor, MAPK and MTOR activator 10.910
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.906
ERCC3excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)0.904
TOR1Atorsin family 1, member A (torsin A)0.902
PTPN13protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)0.898
TTNtitin0.897
TNNC1troponin C type 1 (slow)0.897
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.891
TAB1TGF-beta activated kinase 1/MAP3K7 binding protein 10.890
RHOAras homolog gene family, member A0.889
ATP5OATP synthase, H+ transporting, mitochondrial F1 complex, O subunit0.889
AKT1v-akt murine thymoma viral oncogene homolog 10.879
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.879
ARHGEF11Rho guanine nucleotide exchange factor (GEF) 110.876
RACGAP1Rac GTPase activating protein 10.873
RUVBL1RuvB-like 1 (E. coli)0.866
NCK2NCK adaptor protein 20.865
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.861
RABEP1rabaptin, RAB GTPase binding effector protein 10.855
RAB2ARAB2A, member RAS oncogene family0.852
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.852
UNC119unc-119 homolog (C. elegans)0.850
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.847
STIP1stress-induced-phosphoprotein 10.846
RIN3Ras and Rab interactor 30.839
RAD51RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)0.838
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.838
TNNI1troponin I type 1 (skeletal, slow)0.838
EGFRepidermal growth factor receptor0.835
ATP5A1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle0.835
SH3RF1SH3 domain containing ring finger 10.827
GRB7growth factor receptor-bound protein 70.824
RAB14RAB14, member RAS oncogene family0.824
SEMA4Asema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A0.823
TPM1tropomyosin 1 (alpha)0.813
CFL1cofilin 1 (non-muscle)0.809
HSPH1heat shock 105kDa/110kDa protein 10.807
S100A11S100 calcium binding protein A110.805
MAPK1mitogen-activated protein kinase 10.798
MSH2mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)0.790
RANBP2RAN binding protein 20.789
MDM2Mdm2 p53 binding protein homolog (mouse)0.788
DDX21DEAD (Asp-Glu-Ala-Asp) box polypeptide 210.785
PKN3protein kinase N30.773
S100A1S100 calcium binding protein A10.769
ADRBK1adrenergic, beta, receptor kinase 10.766
FOSFBJ murine osteosarcoma viral oncogene homolog0.762
FGFR1fibroblast growth factor receptor 10.758
RHEBRas homolog enriched in brain0.758
AHSA1AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)0.753
TMED2transmembrane emp24 domain trafficking protein 20.752
RHOGras homolog gene family, member G (rho G)0.739
RALAv-ral simian leukemia viral oncogene homolog A (ras related)0.737
FKBP4FK506 binding protein 4, 59kDa0.735
RHOCras homolog gene family, member C0.732
CCR5chemokine (C-C motif) receptor 50.728
PDCD6IPprogrammed cell death 6 interacting protein0.728
CCNHcyclin H0.725
PSMC5proteasome (prosome, macropain) 26S subunit, ATPase, 50.725
S100A4S100 calcium binding protein A40.723
ATF2activating transcription factor 20.715
HRASv-Ha-ras Harvey rat sarcoma viral oncogene homolog0.712
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ephb2Eph receptor B20.933
Rpgrip1lRpgrip1-like0.908
Lrrk2leucine-rich repeat kinase 20.903
Ntf3neurotrophin 30.888
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.887
Epha4Eph receptor A40.883
BrafBraf transforming gene0.878
Rac1RAS-related C3 botulinum substrate 10.871
Efnb2ephrin B20.858
Arhgef7Rho guanine nucleotide exchange factor (GEF7)0.831
Ptpn11protein tyrosine phosphatase, non-receptor type 110.822
Pafah1b1platelet-activating factor acetylhydrolase, isoform 1b, subunit 10.815
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.814
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.804
Ntrk3neurotrophic tyrosine kinase, receptor, type 30.801
Itsn1intersectin 1 (SH3 domain protein 1A)0.788
Rab5aRAB5A, member RAS oncogene family0.778
Klklotho0.771
Spnb2spectrin beta 20.763
Adrb1adrenergic receptor, beta 10.756
Ccr2chemokine (C-C motif) receptor 20.754
Bmpr2bone morphogenic protein receptor, type II (serine/threonine kinase)0.735
Arrb2arrestin, beta 20.732
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.721
Eea1early endosome antigen 10.720
Grb2growth factor receptor bound protein 20.717
Plxna1plexin A10.707
Igtpinterferon gamma induced GTPase0.700
Hif1ahypoxia inducible factor 1, alpha subunit0.674
Capza2capping protein (actin filament) muscle Z-line, alpha 20.662
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.607
Nf1neurofibromatosis 10.604
Tmem30atransmembrane protein 30A0.584
Tnks1bp1tankyrase 1 binding protein 10.583
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.559
Arhgef11Rho guanine nucleotide exchange factor (GEF) 110.542
Stxbp3asyntaxin binding protein 3A0.541
Cttncortactin0.540
Arhgef12Rho guanine nucleotide exchange factor (GEF) 120.527
Rasgrp1RAS guanyl releasing protein 10.524
Epha1Eph receptor A10.519
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.516
Rasgrp2RAS, guanyl releasing protein 20.514
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.509
Bcl2B-cell leukemia/lymphoma 20.505
Shc3src homology 2 domain-containing transforming protein C30.505
Irgm2immunity-related GTPase family M member 20.504
BaxBCL2-associated X protein0.496
Jupjunction plakoglobin0.493
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.484
Akt1thymoma viral proto-oncogene 10.477
Retret proto-oncogene0.471
Gbp2guanylate binding protein 20.463
Arl1ADP-ribosylation factor-like 10.454
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.454
Lsm2LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)0.414
Ptk2bPTK2 protein tyrosine kinase 2 beta0.407
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.407
Gnao1guanine nucleotide binding protein, alpha O0.404
Ifit1interferon-induced protein with tetratricopeptide repeats 10.397
Ppp1r9bprotein phosphatase 1, regulatory subunit 9B0.394
Sncbsynuclein, beta0.389
Tnni2troponin I, skeletal, fast 20.388
Tsc1tuberous sclerosis 10.382
Eps15epidermal growth factor receptor pathway substrate 150.374
Brca2breast cancer 20.374
SrcRous sarcoma oncogene0.373
Ly6hlymphocyte antigen 6 complex, locus H0.371
Ppp3caprotein phosphatase 3, catalytic subunit, alpha isoform0.371
Myo18amyosin XVIIIA0.370
Atp6v1aATPase, H+ transporting, lysosomal V1 subunit A0.365
XiapX-linked inhibitor of apoptosis0.365
Rab18RAB18, member RAS oncogene family0.364
Vamp2vesicle-associated membrane protein 20.362
Hnf1bHNF1 homeobox B0.362
Ndel1nuclear distribution gene E-like homolog 1 (A. nidulans)0.351
Gfra2glial cell line derived neurotrophic factor family receptor alpha 20.345
Zfand5zinc finger, AN1-type domain 50.344
Pls3plastin 3 (T-isoform)0.344
Cacna1bcalcium channel, voltage-dependent, N type, alpha 1B subunit0.343
Ror1receptor tyrosine kinase-like orphan receptor 10.336
Lamc1laminin, gamma 10.335
Actr3ARP3 actin-related protein 3 homolog (yeast)0.334
Epas1endothelial PAS domain protein 10.331
Sult4a1sulfotransferase family 4A, member 10.330
Gria1glutamate receptor, ionotropic, AMPA1 (alpha 1)0.330
Tgtp2T-cell specific GTPase 20.329
Npas2neuronal PAS domain protein 20.326
RictorRPTOR independent companion of MTOR, complex 20.321
Smarca5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 50.320
Mll3myeloid/lymphoid or mixed-lineage leukemia 30.319
Isg15ISG15 ubiquitin-like modifier0.319
Nos3nitric oxide synthase 3, endothelial cell0.318
Asap1ArfGAP with SH# domain, ankyrin repeat and PH domain10.317
Sept7septin 70.316
Spry4sprouty homolog 4 (Drosophila)0.316
Prkceprotein kinase C, epsilon0.313
Uba3ubiquitin-like modifier activating enzyme 30.312
Mtap2microtubule-associated protein 20.311
Fmnl1formin-like 10.311
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
YPT52Ypt52p0.666
BEM3Bem3p0.626
STE4Ste4p0.603
RHO1Rho1p0.551
YPT31Ypt31p0.532
SSL1Ssl1p0.483
STE11Ste11p0.456
SUI3Sui3p0.445
ISW1Isw1p0.429
STE5Ste5p0.412
YPT1Ypt1p0.392
YIP3Yip3p0.380
TFB4Tfb4p0.379
YDJ1Ydj1p0.379
SPA2Spa2p0.371
STI1Sti1p0.362
TOM1Tom1p0.342
KIN28Kin28p0.330
TFB1Tfb1p0.318
SEC13Sec13p0.312
GYL1Gyl1p0.301
GCD6Gcd6p0.291
AVO1Avo1p0.270
GDI1Gdi1p0.269
SAC6Sac6p0.254
RPN1Rpn1p0.252
MSB3Msb3p0.248
TFA1Tfa1p0.244
TRS65Trs65p0.218
SSA4Ssa4p0.210
STT4Stt4p0.207
KAR2Kar2p0.197
IRA1Ira1p0.196
ACK1Ack1p0.193
ROM2Rom2p0.193
SEC16Sec16p0.191
PRP8Prp8p0.189
PEX1Pex1p0.183
YCS4Ycs4p0.178
SEC3Sec3p0.177
VAC7Vac7p0.175
ELG1Elg1p0.171
POL30Pol30p0.169
MDS3Mds3p0.165
SEC2Sec2p0.160
TFB5Tfb5p0.159
YPT10Ypt10p0.154
KOG1Kog1p0.150
STE2Ste2p0.147
PEP5Pep5p0.145
VPS13Vps13p0.137
YPT53Ypt53p0.135
DDI1Ddi1p0.135
MKT1Mkt1p0.133
ORC1Orc1p0.132
RPT3Rpt3p0.125
BFR1Bfr1p0.124
POL3Pol3p0.123
NOG2Nog2p0.121
YDR026Chypothetical protein0.118
GBP2Gbp2p0.117
BEM4Bem4p0.116
RFC1Rfc1p0.115
UNG1Ung1p0.114
TPM1Tpm1p0.113
CCL1Ccl1p0.112
FKH1Fkh1p0.110
PEX5Pex5p0.110
CCS1Ccs1p0.108
TFB3Tfb3p0.107
RUP1Rup1p0.107
RAD52Rad52p0.104
UBC4Ubc4p0.104
YPT6Ypt6p0.104
ATG13Atg13p0.103
SSL2Ssl2p0.103
PXA1Pxa1p0.103
SGT2Sgt2p0.103
VIP1Vip1p0.102
YLR173Whypothetical protein0.102
INO80Ino80p0.102
SKI3Ski3p0.102
SLA2Sla2p0.102
VPS21Vps21p0.101
DCP2Dcp2p0.100
CDC50Cdc50p0.100
GCD7Gcd7p0.099
SWI1Swi1p0.099
RAD23Rad23p0.098
RPB2Rpb2p0.098
SAC7Sac7p0.096
MCA1Mca1p0.095
PSP2Psp2p0.095
SSK2Ssk2p0.094
PEX6Pex6p0.094
SEC24Sec24p0.094
YPP1Ypp1p0.094
YME1Yme1p0.091
RAD55Rad55p0.090
SEC21Sec21p0.090