The network for 'somitogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms


The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.

NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
myod1myogenic differentiation 10.998
myf5myogenic factor 50.997
gli1GLI-Kruppel family member 10.996
fn1fibronectin 10.996
cdh2cadherin 2, neuronal0.994
tbx16T-box gene 160.993
aldh1a2aldehyde dehydrogenase 1 family, member A20.987
wnt11wingless-type MMTV integration site family, member 110.979
pcdh10bprotocadherin 10b0.979
lef1lymphocyte enhancer binding factor 10.976
jag2jagged 20.976
myhz1.1myosin, heavy polypeptide 1.1, skeletal muscle0.962
bmp4bone morphogenetic protein 40.961
mespamesoderm posterior a0.952
wnt5bwingless-type MMTV integration site family, member 5b0.947
wnt1wingless-type MMTV integration site family, member 10.945
hhiphedgehog interacting protein0.944
hnf1baHNF1 homeobox Ba0.930
her7hairy and enhancer of split related-70.926
her1hairy-related 10.922
wnt3awingless-type MMTV integration site family, member 3A0.919
otx2orthodenticle homolog 20.911
neo1neogenin 10.903
pax7apaired box gene 7a0.898
ntlano tail a0.897
wnt4awingless-type MMTV integration site family, member 4a0.891
fgf17fibroblast growth factor 170.888
foxd5forkhead box D50.886
oepone-eyed pinhead0.879
tbx24T-box 240.871
fezf2FEZ family zinc finger 20.862
bmp2bbone morphogenetic protein 2b0.860
fgf8afibroblast growth factor 8 a0.855
has2hyaluronan synthase 20.855
desmadesmin a0.849
lamb1alaminin, beta 1a0.799
pax2apaired box gene 2a0.785
hes6hairy and enhancer of split 6 (Drosophila)0.784
tp53tumor protein p530.778
eomesaeomesodermin homolog a0.760
gli2aGLI-Kruppel family member GLI2a0.756
sema3aasemaphorin 3aa0.752
tbx1T-box 10.743
pdlim3bPDZ and LIM domain 3b0.735
foxg1aforkhead box G1a0.734
smyhc2slow myosin heavy chain 20.732
fgfr2fibroblast growth factor receptor 20.725
smyhc1slow myosin heavy chain 10.724
her15.1hairy and enhancer of split-related 15.10.719
actc1bactin, alpha, cardiac muscle 1b0.714
fgf3fibroblast growth factor 30.714
ptch1patched 10.693
mespbmesoderm posterior b0.669
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.667
pdlim3aPDZ and LIM domain 3a0.662
igf1insulin-like growth factor 10.661
cdx4caudal type homeo box transcription factor 40.658
ttnbtitin b0.654
ttnatitin a0.649
msgn1mesogenin 10.647
ndr2nodal-related 20.637
ptch2patched 20.635
sox9aSRY-box containing gene 9a0.631
esrraestrogen-related receptor alpha0.624
notch2notch homolog 20.621
supt6hsuppressor of Ty 6 homolog0.614
crip2cysteine-rich protein 20.612
meis1myeloid ecotropic viral integration 10.610
shhasonic hedgehog a0.608
atp1b1aATPase, Na+/K+ transporting, beta 1a polypeptide0.604
notch3notch homolog 30.603
pax3apaired box gene 3a0.603
axin2axin 2 (conductin, axil)0.594
eng2aengrailed 2a0.591
dbx1adeveloping brain homeobox 1a0.581
kdrlkinase insert domain receptor like0.577
sox17SRY-box containing gene 170.576
cxcr4achemokine (C-X-C motif) receptor 4a0.558
nr2e1nuclear receptor subfamily 2, group E, member 10.551
prkciprotein kinase C, iota0.538
itga5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.525
neurog1neurogenin 10.516
cyp19a1bcytochrome P450, family 19, subfamily A, polypeptide 1b0.516
spry4sprouty (Drosophila) homolog 40.516
dmrt2adoublesex and mab-3 related transcription factor 2a0.513
rx3retinal homeobox gene 30.509
epha4beph receptor A4b0.504
emx3empty spiracles homeobox 30.498
pcdh8protocadherin 80.493
bocbrother of CDO0.487
snai1bsnail homolog 1b (Drosophila)0.485
lama5laminin, alpha 50.485
tll1tolloid-like 10.484
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.995
FN1fibronectin 10.973
SMAD2SMAD family member 20.972
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.968
LRP6low density lipoprotein receptor-related protein 60.946
PSEN1presenilin 10.942
MEOX2mesenchyme homeobox 20.933
PAX3paired box 30.924
FLNAfilamin A, alpha0.922
BBS2Bardet-Biedl syndrome 20.871
FLNBfilamin B, beta0.860
ATXN1ataxin 10.839
PGK1phosphoglycerate kinase 10.826
BMP2bone morphogenetic protein 20.825
TRRAPtransformation/transcription domain-associated protein0.816
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.803
ERBB2IPerbb2 interacting protein0.794
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.772
JAG1jagged 10.767
SMAD7SMAD family member 70.763
PGAM1phosphoglycerate mutase 1 (brain)0.749
MAPK8IP1mitogen-activated protein kinase 8 interacting protein 10.744
PAX1paired box 10.700
GSK3Bglycogen synthase kinase 3 beta0.672
SRPK2SRSF protein kinase 20.655
MEOX1mesenchyme homeobox 10.611
HIPK2homeodomain interacting protein kinase 20.572
MAPK8mitogen-activated protein kinase 80.552
APCadenomatous polyposis coli0.539
SMURF2SMAD specific E3 ubiquitin protein ligase 20.487
ACTR3ARP3 actin-related protein 3 homolog (yeast)0.473
AKT1v-akt murine thymoma viral oncogene homolog 10.459
SOX10SRY (sex determining region Y)-box 100.440
CREBBPCREB binding protein0.423
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.412
ZFXzinc finger protein, X-linked0.408
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.375
ITGB1BP3integrin beta 1 binding protein 30.370
PKM2pyruvate kinase, muscle0.367
SMAD4SMAD family member 40.355
ARPC2actin related protein 2/3 complex, subunit 2, 34kDa0.352
ACTG1actin, gamma 10.349
GAPDHglyceraldehyde-3-phosphate dehydrogenase0.336
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.334
ATXN7ataxin 70.325
POU3F2POU class 3 homeobox 20.317
TCF4transcription factor 40.316
CYR61cysteine-rich, angiogenic inducer, 610.315
MED24mediator complex subunit 240.299
TBK1TANK-binding kinase 10.294
FZD1frizzled homolog 1 (Drosophila)0.292
TCF7L2transcription factor 7-like 2 (T-cell specific, HMG-box)0.288
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.282
QKIquaking homolog, KH domain RNA binding (mouse)0.280
HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 10.278
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.274
MAML1mastermind-like 1 (Drosophila)0.269
USP9Xubiquitin specific peptidase 9, X-linked0.261
BZW1basic leucine zipper and W2 domains 10.256
NAA15N(alpha)-acetyltransferase 15, NatA auxiliary subunit0.246
GADD45GIP1growth arrest and DNA-damage-inducible, gamma interacting protein 10.245
PCM1pericentriolar material 10.224
LDHAlactate dehydrogenase A0.223
CAV2caveolin 20.222
MED12mediator complex subunit 120.222
CDC73cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.220
CFL1cofilin 1 (non-muscle)0.216
SKIv-ski sarcoma viral oncogene homolog (avian)0.208
CDH11cadherin 11, type 2, OB-cadherin (osteoblast)0.206
ESR1estrogen receptor 10.205
ARPC5actin related protein 2/3 complex, subunit 5, 16kDa0.203
SMAD3SMAD family member 30.203
DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked0.201
ACTBactin, beta0.195
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.195
TAF4TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa0.193
SPENspen homolog, transcriptional regulator (Drosophila)0.190
DKK1dickkopf homolog 1 (Xenopus laevis)0.188
IGF2Rinsulin-like growth factor 2 receptor0.186
CTGFconnective tissue growth factor0.185
SMURF1SMAD specific E3 ubiquitin protein ligase 10.181
MBNL1muscleblind-like (Drosophila)0.179
BMP1bone morphogenetic protein 10.177
XIAPX-linked inhibitor of apoptosis0.177
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.176
EIF4Eeukaryotic translation initiation factor 4E0.172
EP300E1A binding protein p3000.170
BTRCbeta-transducin repeat containing0.166
SIRT1sirtuin 10.162
MYH9myosin, heavy chain 9, non-muscle0.161
SPDEFSAM pointed domain containing ets transcription factor0.157
EXOC7exocyst complex component 70.153
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.149
ZFYVE9zinc finger, FYVE domain containing 90.149
GLIS2GLIS family zinc finger 20.146
MED15mediator complex subunit 150.146
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Otx2orthodenticle homolog 2 (Drosophila)1.000
Pax3paired box gene 31.000
Pitx2paired-like homeodomain transcription factor 21.000
Foxc1forkhead box C11.000
Gli3GLI-Kruppel family member GLI31.000
Six1sine oculis-related homeobox 1 homolog (Drosophila)1.000
Tbx1T-box 11.000
Fgf8fibroblast growth factor 81.000
Msx1homeobox, msh-like 11.000
Rargretinoic acid receptor, gamma1.000
Fgfr1fibroblast growth factor receptor 10.999
Psen1presenilin 10.999
Eya1eyes absent 1 homolog (Drosophila)0.999
Foxg1forkhead box G10.999
Prrx1paired related homeobox 10.999
Hand2heart and neural crest derivatives expressed transcript 20.999
Bmp4bone morphogenetic protein 40.998
Foxc2forkhead box C20.998
Ctnnb1catenin (cadherin associated protein), beta 10.998
Tbx3T-box 30.997
Fgfr2fibroblast growth factor receptor 20.997
Tcfap2atranscription factor AP-2, alpha0.996
Dlx5distal-less homeobox 50.995
Fgf10fibroblast growth factor 100.991
Wnt3awingless-related MMTV integration site 3A0.989
Lef1lymphoid enhancer binding factor 10.988
Lhx1LIM homeobox protein 10.988
Emx1empty spiracles homolog 1 (Drosophila)0.987
Pax2paired box gene 20.984
Hoxa1homeobox A10.984
Tgfb2transforming growth factor, beta 20.984
Pax6paired box gene 60.984
Lmx1aLIM homeobox transcription factor 1 alpha0.982
Gscgoosecoid homeobox0.978
Hoxa3homeobox A30.977
Notch1Notch gene homolog 1 (Drosophila)0.977
Vegfavascular endothelial growth factor A0.974
Hes1hairy and enhancer of split 1 (Drosophila)0.974
Bdnfbrain derived neurotrophic factor0.971
Bmp7bone morphogenetic protein 70.971
Lmx1bLIM homeobox transcription factor 1 beta0.970
Prrx2paired related homeobox 20.967
Smosmoothened homolog (Drosophila)0.966
Lrp6low density lipoprotein receptor-related protein 60.965
Chd7chromodomain helicase DNA binding protein 70.965
Rb1retinoblastoma 10.962
Zic3zinc finger protein of the cerebellum 30.962
Ednraendothelin receptor type A0.960
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.959
Sox2SRY-box containing gene 20.958
Msx2homeobox, msh-like 20.957
Hoxa2homeobox A20.957
Emx2empty spiracles homolog 2 (Drosophila)0.950
Meox2mesenchyme homeobox 20.949
Hand1heart and neural crest derivatives expressed transcript 10.934
Cdkn1bcyclin-dependent kinase inhibitor 1B0.929
Gata4GATA binding protein 40.929
Vangl2vang-like 2 (van gogh, Drosophila)0.929
Snai1snail homolog 1 (Drosophila)0.926
Pax8paired box gene 80.919
Foxh1forkhead box H10.917
Otx1orthodenticle homolog 1 (Drosophila)0.917
Hoxa13homeobox A130.917
Gli2GLI-Kruppel family member GLI20.914
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.913
Rarbretinoic acid receptor, beta0.907
Acvr1activin A receptor, type 10.897
En1engrailed 10.887
Hoxd13homeobox D130.879
Gbx2gastrulation brain homeobox 20.877
Smad3MAD homolog 3 (Drosophila)0.866
Pbx1pre B-cell leukemia transcription factor 10.857
MecomMDS1 and EVI1 complex locus0.855
Wnt6wingless-related MMTV integration site 60.853
Apcadenomatosis polyposis coli0.853
Wt1Wilms tumor 1 homolog0.851
Gdnfglial cell line derived neurotrophic factor0.846
Neurod1neurogenic differentiation 10.843
Gata6GATA binding protein 60.836
Twist2twist homolog 2 (Drosophila)0.834
Dlx2distal-less homeobox 20.827
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.816
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.810
Tbx2T-box 20.809
LfngLFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase0.805
Mesp1mesoderm posterior 10.804
Nr5a1nuclear receptor subfamily 5, group A, member 10.801
Ror2receptor tyrosine kinase-like orphan receptor 20.782
Sox9SRY-box containing gene 90.779
Dkk1dickkopf homolog 1 (Xenopus laevis)0.778
Ascl1achaete-scute complex homolog 1 (Drosophila)0.776
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.773
Sox11SRY-box containing gene 110.771
Pax9paired box gene 90.769
Pitx1paired-like homeodomain transcription factor 10.741
Fgf15fibroblast growth factor 150.739
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism