The network for 'catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

catabolic process

The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.

NameDescriptionProbabilityFunc Analog Organism
rpn-12Protein RPN-120.875
pas-4Protein PAS-40.860
atp-2Protein ATP-20.845
egl-18Protein EGL-180.731
vab-3Protein VAB-30.693
rpt-3Protein RPT-30.670
pkg-1Protein PKG-10.655
tpxl-1Protein TPXL-10.628
sem-5Protein SEM-50.628
egl-13Protein EGL-130.612
dlc-1Protein DLC-10.597
rnr-1Protein RNR-10.570
atn-1Protein ATN-10.560
hel-1Protein HEL-10.555
app-1Protein APP-10.553
vps-28Protein VPS-280.544
unc-52Protein UNC-520.528
rpt-2Protein RPT-20.496
unc-54Protein UNC-540.495
npl-4.2Protein NPL-4.20.492
pqn-59Protein PQN-590.486
unc-9Protein UNC-90.481
pkc-3Protein PKC-30.476
pcm-1Protein PCM-10.476
rpa-1Protein RPA-10.473
ucr-2.3Protein UCR-2.30.470
tba-2Protein TBA-20.469
sqt-1Protein SQT-10.467
egl-36Protein EGL-360.465
vab-1Protein VAB-10.462
D1081.8Protein D1081.80.455
pbs-5Protein PBS-50.448
lin-37Protein LIN-370.445
pmk-1Protein PMK-10.444
lin-45Protein LIN-450.443
zen-4Protein ZEN-40.441
ced-9Protein CED-90.427
CELE_Y57G11C.3Protein Y57G11C.30.425
goa-1Protein GOA-10.423
eat-6Protein EAT-60.420
rpn-6.1Protein RPN-6.10.419
zyx-1Protein ZYX-10.417
col-157Protein COL-1570.415
idhb-1Protein IDHB-10.400
let-60Protein LET-600.400
col-49Protein COL-490.398
nlg-1Protein NLG-10.395
rab-1Protein RAB-10.388
rol-8Protein ROL-80.378
K10C8.1Protein K10C8.10.377
unc-85Protein UNC-850.377
lntl-1Protein LNTL-10.371
fkb-6Protein FKB-60.369
ZK688.3Protein ZK688.30.367
wrt-6Protein WRT-60.366
bec-1Protein BEC-10.364
pbs-1Protein PBS-10.363
alx-1Protein ALX-10.363
unc-23Protein UNC-230.361
F56C9.10Protein F56C9.100.359
sli-1Protein SLI-10.357
Y32F6B.1Protein Y32F6B.10.355
cka-2Protein CKA-20.355
T23F11.1Protein T23F11.10.355
prx-5Protein PRX-50.355
bmk-1Protein BMK-10.355
elpc-4Protein ELPC-40.354
ZK899.2Protein ZK899.20.353
dpy-13Protein DPY-130.353
rbg-2Protein RBG-20.353
pri-2Protein PRI-20.351
itr-1Protein ITR-10.349
csr-1Protein CSR-10.348
npp-19Protein NPP-190.345
crt-1Protein CRT-10.344
par-5Protein PAR-50.344
CELE_Y39G10AR.15Protein Y39G10AR.150.340
rab-6.1Protein RAB-6.10.340
col-154Protein COL-1540.338
cki-2Protein CKI-20.335
dim-1Protein DIM-10.334
F22D3.2Protein F22D3.20.332
pbs-6Protein PBS-60.332
dpy-30Protein DPY-300.330
mel-26Protein MEL-260.330
bli-1Protein BLI-10.327
egl-30Protein EGL-300.323
spr-4Protein SPR-40.321
CELE_F52E1.13Protein F52E1.130.320
F26E4.3Protein F26E4.30.320
rhgf-2Protein RHGF-20.320
rpn-7Protein RPN-70.317
col-119Protein COL-1190.315
inx-15Protein INX-150.313
pgl-1Protein PGL-10.312
rpt-5Protein RPT-50.312
cye-1Protein CYE-10.312
col-101Protein COL-1010.311
ifa-1Protein IFA-10.310
rab-5Protein RAB-50.310
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
arnt2aryl hydrocarbon receptor nuclear translocator 20.715
psmb1proteasome (prosome, macropain) subunit, beta type, 10.369
pcnaproliferating cell nuclear antigen0.343
aldocbaldolase C, fructose-bisphosphate, b0.311
hspa5heat shock protein 50.228
mosv-mos Moloney murine sarcoma viral oncogene homolog0.203
psmb2proteasome (prosome, macropain) subunit, beta type, 20.199
actn2actinin, alpha 20.194
prdm1aPR domain containing 1a, with ZNF domain0.172
psmb3proteasome (prosome, macropain) subunit, beta type, 30.171
spsb4asplA/ryanodine receptor domain and SOCS box containing 4a0.169
bmp4bone morphogenetic protein 40.165
myhz2myosin, heavy polypeptide 2, fast muscle specific0.155
plxnb2aplexin b2a0.155
ccnb1cyclin B10.150
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.148
adipor2adiponectin receptor 20.139
pou5f1POU domain, class 5, transcription factor 10.131
hsp90a.2heat shock protein 90-alpha 20.126
epb41l5erythrocyte membrane protein band 4.1 like 50.126
psma6aproteasome (prosome, macropain) subunit, alpha type, 6a0.119
psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.119
crabp2acellular retinoic acid binding protein 2, a0.109
sox9bSRY-box containing gene 9b0.104
psma8proteasome (prosome, macropain) subunit, alpha type, 80.104
psmb4proteasome (prosome, macropain) subunit, beta type, 40.104
psmd4bproteasome (prosome, macropain) 26S subunit, non-ATPase, 4b0.096
fstl1bfollistatin-like 1b0.094
tnni2a.4troponin I, skeletal, fast 2a.40.092
LOC799612prolactin 20.090
psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.088
gdf6agrowth differentiation factor 6a0.088
gata5GATA-binding protein 50.088
gro2groucho 20.086
psma4proteasome (prosome, macropain) subunit, alpha type, 40.086
dnm1ldynamin 1-like0.086
psma5proteasome (prosome, macropain) subunit, alpha type,50.085
itgb1b.2integrin, beta 1b.20.084
psmc3proteasome (prosome, macropain) 26S subunit, ATPase, 30.082
chdchordin0.082
nf1aneurofibromin 1a0.081
smad2MAD homolog 2 (Drosophila)0.080
puf60bpoly-U binding splicing factor b0.078
ncor1nuclear receptor co-repressor 10.078
smyhc1slow myosin heavy chain 10.077
celsr3cadherin, EGF LAG seven-pass G-type receptor 30.075
actn3aactinin alpha 3a0.075
fabp11afatty acid binding protein 11a0.072
tbx1T-box 10.072
ck2bcasein kinase 2 beta0.072
atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.072
psmc6proteasome (prosome, macropain) 26S subunit, ATPase, 60.070
bc2putative breast adenocarcinoma marker0.070
hspd1heat shock 60kD protein 1 (chaperonin)0.066
fmr1fragile X mental retardation 10.066
aurkbaurora kinase B0.066
pkd2polycystic kidney disease 20.065
ccnb2cyclin B20.064
dhfrdihydrofolate reductase0.064
fanclFanconi anemia, complementation group L0.064
ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.064
itgb1bintegrin, beta 1b0.064
psmc1aproteasome (prosome, macropain) 26S subunit, ATPase, 1a0.064
zgc:92775zgc:927750.063
mpp5amembrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)0.063
ddx42DEAD (Asp-Glu-Ala-Asp) box polypeptide 420.062
cand1cullin-associated and neddylation-dissociated 10.059
hspa4aheat shock protein 4a0.058
rae1RAE1 RNA export 1 homolog (S. pombe)0.058
trpm7transient receptor potential cation channel, subfamily M, member 70.057
rap1bRAS related protein 1b0.056
psmb5proteasome (prosome, macropain) subunit, beta type, 50.055
desmadesmin a0.055
myhz1.1myosin, heavy polypeptide 1.1, skeletal muscle0.055
acheacetylcholinesterase0.055
nadl1.2neural adhesion molecule L1.20.053
fhlafour and a half LIM domains a0.053
mmp14bmatrix metalloproteinase 14b (membrane-inserted)0.053
ilkintegrin linked kinase0.052
wnt1wingless-type MMTV integration site family, member 10.052
cdc25cell division cycle 25 homolog0.051
sass6spindle assembly 6 homolog (C. elegans)0.050
zgc:73142zgc:731420.050
bmp2bbone morphogenetic protein 2b0.050
ahcyS-adenosylhomocysteine hydrolase0.049
zbtb4zinc finger and BTB domain containing 40.049
sema3aasemaphorin 3aa0.049
dnajb6bDnaJ (Hsp40) homolog, subfamily B, member 6b0.049
ass1argininosuccinate synthetase 10.049
myhz1.2myosin, heavy polypeptide 1.2, skeletal muscle0.048
rbm4.2RNA binding motif protein 4.20.048
mtpmicrosomal triglyceride transfer protein0.048
adipor1aadiponectin receptor 1a0.048
zgc:101071zgc:1010710.048
hoxb3ahomeo box B3a0.048
gapdhglyceraldehyde-3-phosphate dehydrogenase0.047
rp42-penrp42 homolog (pending) and rp42 homolog0.047
aldh7a1aldehyde dehydrogenase 7 family, member A10.047
psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.047
nos2bnitric oxide synthase 2b, inducible0.047
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Pi3K92ECG4141 gene product from transcript CG4141-RB0.996
saxsaxophone0.988
EcREcdysone receptor0.986
CG11347CG11347 gene product from transcript CG11347-RE0.952
shishibire0.948
Atg8aAutophagy-specific gene 8a0.931
RhebCG1081 gene product from transcript CG1081-RA0.929
dcodiscs overgrown0.915
RhoGEF2CG9635 gene product from transcript CG9635-RF0.888
Rpt1CG1341 gene product from transcript CG1341-RA0.882
mbcmyoblast city0.876
TorTarget of rapamycin0.867
Atg18Autophagy-specific gene 180.862
Dcr-2Dicer-20.855
babobaboon0.847
Atg1Autophagy-specific gene 10.841
Stat92ESignal-transducer and activator of transcription protein at 92E0.835
Syx7Syntaxin 70.834
giggigas0.822
Rho1CG8416 gene product from transcript CG8416-RB0.816
p53CG33336 gene product from transcript CG33336-RB0.815
cpacapping protein alpha0.814
TER94CG2331 gene product from transcript CG2331-RA0.813
StamSignal transducing adaptor molecule0.812
Su(H)Suppressor of Hairless0.805
benbendless0.790
ykiyorkie0.783
CG7998CG7998 gene product from transcript CG7998-RA0.778
Nup154Nucleoporin 1540.774
rinrasputin0.765
scnyscrawny0.764
Rpd3CG7471 gene product from transcript CG7471-RA0.763
Dhc64CDynein heavy chain 64C0.753
Itp-r83AInositol 1,4,5,-tris-phosphate receptor0.736
B52CG10851 gene product from transcript CG10851-RB0.726
ArgkArginine kinase0.721
awdabnormal wing discs0.718
locolocomotion defects0.712
AxnAxin0.711
PvrPDGF- and VEGF-receptor related0.707
Fmr1CG6203 gene product from transcript CG6203-RC0.706
NNotch0.700
Rpn11CG18174 gene product from transcript CG18174-RA0.699
SmoxSmad on X0.697
mysmyospheroid0.696
MiroMitochondrial Rho0.685
lin19lin-19-like0.682
Ras85DRas oncogene at 85D0.668
tsrtwinstar0.667
myoglianinCG1838 gene product from transcript CG1838-RD0.665
Akt1CG4006 gene product from transcript CG4006-RA0.660
Rpn2CG11888 gene product from transcript CG11888-RA0.657
ncdnon-claret disjunctional0.654
beta-Specbeta Spectrin0.652
alpha-Specalpha Spectrin0.640
RfabgRetinoid- and fatty acid-binding glycoprotein0.640
Aos1CG12276 gene product from transcript CG12276-RA0.638
Pros26.4Proteasome 26S subunit subunit 4 ATPase0.633
GugGrunge0.632
par-1CG8201 gene product from transcript CG8201-RA0.630
RASSF8CG5053 gene product from transcript CG5053-RA0.624
Rac1CG2248 gene product from transcript CG2248-RA0.617
FhosCG42610 gene product from transcript CG42610-RC0.614
dmdiminutive0.609
ifinflated0.606
GdhGlutamate dehydrogenase0.592
CatCatalase0.589
MadMothers against dpp0.572
MntCG13316 gene product from transcript CG13316-RD0.569
MoeMoesin0.565
wupAwings up A0.563
CG1347CG1347 gene product from transcript CG1347-RB0.562
PakPAK-kinase0.550
jarjaguar0.549
Sin3ACG8815 gene product from transcript CG8815-RC0.546
CSN5COP9 complex homolog subunit 50.535
dupdouble parked0.534
nosnanos0.531
rlrolled0.530
RecQ4CG7487 gene product from transcript CG7487-RA0.529
ird1immune response deficient 10.526
NrtNeurotactin0.524
gwlgreatwall0.522
drkdownstream of receptor kinase0.521
spasspastin0.519
SnapSoluble NSF attachment protein0.515
Vps16AVacuolar protein sorting 16A0.513
nejnejire0.497
RagACG11968 gene product from transcript CG11968-RA0.497
Sir2CG5216 gene product from transcript CG5216-RA0.494
alpha-AdaptinCG4260 gene product from transcript CG4260-RA0.491
Prosbeta5Proteasome beta5 subunit0.486
Rab5Rab-protein 50.481
WnkCG7177 gene product from transcript CG7177-RA0.479
CkIIalphaCasein kinase II alpha subunit0.479
Atg6Autophagy-specific gene 60.478
DrefDNA replication-related element factor0.476
Ada2bCG9638 gene product from transcript CG9638-RA0.475
mspsmini spindles0.473
keykenny0.468
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ech1enoyl coenzyme A hydratase 1, peroxisomal0.821
Psma5proteasome (prosome, macropain) subunit, alpha type 50.785
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.726
Hk1hexokinase 10.720
Acaa2acetyl-Coenzyme A acyltransferase 20.713
Ugt1a6UDP glucuronosyltransferase 1 family, polypeptide A60.706
Ldhalactate dehydrogenase A0.706
Pja2praja 2, RING-H2 motif containing0.697
Gstm1glutathione S-transferase mu 10.645
Acadlacyl-Coenzyme A dehydrogenase, long-chain0.641
Cyp2b1cytochrome P450, family 2, subfamily b, polypeptide 10.635
Psma7proteasome (prosome, macropain) subunit, alpha type 70.629
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.580
Psmb4proteasome (prosome, macropain) subunit, beta type 40.578
Papolapoly (A) polymerase alpha0.533
Aldoaaldolase A, fructose-bisphosphate0.531
Mgst2microsomal glutathione S-transferase 20.524
Etfbelectron-transfer-flavoprotein, beta polypeptide0.523
Casp3caspase 30.519
Psma2proteasome (prosome, macropain) subunit, alpha type 20.496
Txn1thioredoxin 10.491
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)0.478
Anxa4annexin A40.477
Cyp4f4cytochrome P450, family 4, subfamily f, polypeptide 40.453
LOC494499LOC494499 protein0.451
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.448
Ephx1epoxide hydrolase 1, microsomal0.446
Gpx4glutathione peroxidase 40.446
Abcc2ATP-binding cassette, subfamily C (CFTR/MRP), member 20.446
Acadvlacyl-Coenzyme A dehydrogenase, very long chain0.444
Cttncortactin0.443
Akap1A kinase (PRKA) anchor protein 10.441
Actr3ARP3 actin-related protein 3 homolog (yeast)0.441
Tpm3tropomyosin 3, gamma0.437
Aldh9a1aldehyde dehydrogenase 9 family, member A10.426
Psmb3proteasome (prosome, macropain) subunit, beta type 30.416
G6pcglucose-6-phosphatase, catalytic subunit0.399
Csnk1dcasein kinase 1, delta0.395
Lgals3lectin, galactoside-binding, soluble, 30.393
Tpi1triosephosphate isomerase 10.384
Ctbschitobiase, di-N-acetyl-0.379
Gipc1GIPC PDZ domain containing family, member 10.379
Prkchprotein kinase C, eta0.377
LOC293989cytochrome P450-like0.376
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.376
Psma3proteasome (prosome, macropain) subunit, alpha type 30.374
Gstm5glutathione S-transferase, mu 50.370
Morf4l2mortality factor 4 like 20.363
Pdk2pyruvate dehydrogenase kinase, isozyme 20.363
Psma1proteasome (prosome, macropain) subunit, alpha type 10.361
Taok1TAO kinase 10.355
Gsta5glutathione S-transferase Yc2 subunit0.354
Cyp2a1cytochrome P450, family 2, subfamily a, polypeptide 10.353
Acox1acyl-Coenzyme A oxidase 1, palmitoyl0.352
Psmb5proteasome (prosome, macropain) subunit, beta type 50.350
Ube2iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.348
Pfn1profilin 10.347
Dnajc5DnaJ (Hsp40) homolog, subfamily C, member 50.342
Stxbp1syntaxin binding protein 10.335
Mapre1microtubule-associated protein, RP/EB family, member 10.334
Cdc42bpbCDC42 binding protein kinase beta (DMPK-like)0.334
Lamp2lysosomal-associated membrane protein 20.330
Litaflipopolysaccharide-induced TNF factor0.324
Decr12,4-dienoyl CoA reductase 1, mitochondrial0.324
Ctsl1cathepsin L10.320
Pkm2pyruvate kinase, muscle0.318
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.316
Psmb6proteasome (prosome, macropain) subunit, beta type 60.313
Adam7ADAM metallopeptidase domain 70.311
Cyp2c23cytochrome P450, family 2, subfamily c, polypeptide 230.311
Apobapolipoprotein B0.309
Ripk3receptor-interacting serine-threonine kinase 30.309
Nr0b2nuclear receptor subfamily 0, group B, member 20.308
Camk4calcium/calmodulin-dependent protein kinase IV0.307
Abp10annexin V-binding protein ABP-100.306
LOC100134871beta globin minor gene0.305
Pbsnprobasin0.302
Ntrk1neurotrophic tyrosine kinase, receptor, type 10.299
Cyp2b3cytochrome P450, family 2, subfamily b, polypeptide 30.296
Acadmacyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain0.296
Cyp4f1cytochrome P450, family 4, subfamily f, polypeptide 10.292
Atp1b1ATPase, Na+/K+ transporting, beta 1 polypeptide0.291
Psma4proteasome (prosome, macropain) subunit, alpha type 40.291
Cacna1acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.291
Acy1aminoacylase 10.290
Gipgastric inhibitory polypeptide0.287
Ube2d3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.287
Atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.285
Cox4i1cytochrome c oxidase subunit IV isoform 10.284
Gcdhglutaryl-Coenzyme A dehydrogenase0.283
Pdia4protein disulfide isomerase family A, member 40.282
Anpepalanyl (membrane) aminopeptidase0.278
Rhoaras homolog gene family, member A0.277
Psme2proteasome (prosome, macropain) activator subunit 20.276
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.274
Gckglucokinase0.273
Prdx5peroxiredoxin 50.272
Cyp4a10cytochrome P450, family 4, subfamily a, polypeptide 100.272
Slc7a2solute carrier family 7 (cationic amino acid transporter, y+ system), member 20.272
Pebp1phosphatidylethanolamine binding protein 10.272
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism