The network for 'cellular catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular catabolic process

The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.

NameDescriptionProbabilityFunc Analog Organism
rpn-12Protein RPN-120.833
egl-18Protein EGL-180.815
rpt-2Protein RPT-20.690
rpn-7Protein RPN-70.684
rsp-8Protein RSP-80.568
par-5Protein PAR-50.547
rpt-5Protein RPT-50.508
CELE_Y57G11C.3Protein Y57G11C.30.508
rnr-1Protein RNR-10.481
rpn-6.1Protein RPN-6.10.458
rpt-3Protein RPT-30.440
atp-2Protein ATP-20.435
pbs-1Protein PBS-10.426
zen-4Protein ZEN-40.414
pcm-1Protein PCM-10.405
rpn-5Protein RPN-50.391
Y97E10AR.6Protein Y97E10AR.60.388
rpn-10Protein RPN-100.386
mei-1Protein MEI-10.373
F56D2.6Protein F56D2.60.368
pas-4Protein PAS-40.336
acs-4Protein ACS-40.331
sma-6Protein SMA-60.331
pas-2Protein PAS-20.316
csr-1Protein CSR-10.313
cki-2Protein CKI-20.310
csn-3Protein CSN-30.307
CELE_C39E9.11Protein C39E9.110.306
pbs-5Protein PBS-50.297
unc-51Protein UNC-510.296
Y47D3A.29Protein Y47D3A.290.278
rod-1Protein ROD-10.278
cyk-4Protein CYK-40.275
dpy-31Protein DPY-310.274
K10C9.3Protein K10C9.30.273
pkc-3Protein PKC-30.273
pkg-1Protein PKG-10.272
app-1Protein APP-10.270
pptr-2Protein PPTR-20.266
chc-1Protein CHC-10.265
rpn-11Protein RPN-110.263
C56G2.7Protein C56G2.70.261
rpn-9Protein RPN-90.260
CELE_Y48B6A.1Protein Y48B6A.10.257
cin-4Protein CIN-40.253
atx-3Protein ATX-30.252
ire-1Protein IRE-10.251
cul-1Protein CUL-10.245
npl-4.2Protein NPL-4.20.244
D1081.8Protein D1081.80.243
mvb-12Protein MVB-120.243
tpxl-1Protein TPXL-10.242
smc-3Protein SMC-30.241
cdl-1Protein CDL-10.238
F53F10.2Protein F53F10.20.238
wdfy-2Protein WDFY-20.238
nck-1Protein NCK-10.237
rpa-1Protein RPA-10.236
rpa-2Protein RPA-20.235
F55G1.5Protein F55G1.50.234
npp-19Protein NPP-190.233
pri-2Protein PRI-20.233
CELE_C10C6.6Protein C10C6.60.232
vab-1Protein VAB-10.231
stam-1Protein STAM-10.228
tba-2Protein TBA-20.224
tag-315Protein TAG-3150.224
gpb-1Protein GPB-10.220
gck-2Protein GCK-20.219
crt-1Protein CRT-10.218
C33H5.17Protein C33H5.170.218
ykt-6Protein YKT-60.218
npp-1Protein NPP-10.216
mbk-1Protein MBK-10.215
npl-4.1Protein NPL-4.10.215
lsl-1Protein LSL-10.214
ncx-1Protein NCX-10.213
goa-1Protein GOA-10.212
ucr-2.3Protein UCR-2.30.212
CELE_T10D4.6Protein T10D4.60.211
miro-1Protein MIRO-10.209
scc-3Protein SCC-30.209
C41D11.3Protein C41D11.30.207
letm-1Protein LETM-10.207
sem-5Protein SEM-50.207
mtm-9Protein MTM-90.206
mpz-2Protein MPZ-20.205
dlc-1Protein DLC-10.204
lag-1Protein LAG-10.203
tag-298Protein TAG-2980.203
hgrs-1Protein HGRS-10.203
dnc-2Protein DNC-20.202
ace-1Protein ACE-10.202
rab-1Protein RAB-10.202
mcm-7Protein MCM-70.201
cct-6Protein CCT-60.200
ceh-58Protein CEH-580.199
pap-1Protein PAP-10.196
rgl-1Protein RGL-10.195
hmg-1.2Protein HMG-1.20.194
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
ncor1nuclear receptor co-repressor 10.402
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.370
snai1asnail homolog 1a (Drosophila)0.354
hspa5heat shock protein 50.343
prdm1aPR domain containing 1a, with ZNF domain0.329
psmb1proteasome (prosome, macropain) subunit, beta type, 10.298
pitx3paired-like homeodomain transcription factor 30.249
atp1b3bATPase, Na+/K+ transporting, beta 3b polypeptide0.231
gdf6agrowth differentiation factor 6a0.225
atp6v0caATPase, H+ transporting, lysosomal, V0 subunit c, a0.208
bmp4bone morphogenetic protein 40.195
ppp1r12aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.187
rab1aRAB1A, member RAS oncogene family0.170
tp53tumor protein p530.167
ccnb1cyclin B10.136
psmc6proteasome (prosome, macropain) 26S subunit, ATPase, 60.128
tnnt3btroponin T3b, skeletal, fast0.121
sox9bSRY-box containing gene 9b0.119
hadhahydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase, alpha subunit0.115
aldh7a1aldehyde dehydrogenase 7 family, member A10.114
ddx42DEAD (Asp-Glu-Ala-Asp) box polypeptide 420.113
sumo3aSMT3 suppressor of mif two 3 homolog 3a0.106
psmb2proteasome (prosome, macropain) subunit, beta type, 20.103
mecp2methyl CpG binding protein 20.103
arf5ADP-ribosylation factor 50.100
psen1presenilin 10.099
plxnb2aplexin b2a0.099
pax8paired box gene 80.099
psmd4bproteasome (prosome, macropain) 26S subunit, non-ATPase, 4b0.098
psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.097
pou5f1POU domain, class 5, transcription factor 10.095
gcm2glial cells missing homolog 2 (Drosophila)0.095
tgfb3transforming growth factor, beta 30.093
sec61al1Sec61 alpha like 10.087
psma5proteasome (prosome, macropain) subunit, alpha type,50.086
bnip3lbBCL2/adenovirus E1B interacting protein 3-like b0.084
gnb1aguanine nucleotide binding protein (G protein), beta polypeptide 1a0.077
fcho2FCH domain only 20.076
ndufs4NADH dehydrogenase (ubiquinone) Fe-S protein 4, (NADH-coenzyme Q reductase)0.075
atp6v1hATPase, H+ transporting, lysosomal, V1 subunit H0.073
smad5MAD homolog 5 (Drosophila)0.072
arnt2aryl hydrocarbon receptor nuclear translocator 20.071
ranras-related nuclear protein0.071
nhp2l1NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)0.070
psmd1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.068
junjun proto-oncogene0.068
tpm4tropomyosin 40.067
sec61al2Sec61 alpha like 20.067
psmb3proteasome (prosome, macropain) subunit, beta type, 30.067
yes1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 10.067
smad2MAD homolog 2 (Drosophila)0.067
ccnb2cyclin B20.066
bcl2l10BCL2-like 10 (apoptosis facilitator)0.066
angptl3angiopoietin-like 30.065
cmybtranscription factor cmyb0.064
nploc4nuclear protein localization 4 homolog (S. cerevisiae)0.062
aldh18a1aldehyde dehydrogenase 18 family, member A10.061
usp5ubiquitin specific protease 50.061
mifmacrophage migration inhibitory factor0.059
ccna2cyclin A20.059
cand1cullin-associated and neddylation-dissociated 10.058
dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.058
ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.057
grinaglutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)0.056
furinafurin (paired basic amino acid cleaving enzyme) a0.056
spsb4asplA/ryanodine receptor domain and SOCS box containing 4a0.055
gna12guanine nucleotide binding protein (G protein) alpha 120.055
park7parkinson disease (autosomal recessive, early onset) 70.055
bsdc1BSD domain containing 10.054
ilf2interleukin enhancer binding factor 20.054
tnni2a.4troponin I, skeletal, fast 2a.40.054
sass6spindle assembly 6 homolog (C. elegans)0.054
mcl1bmyeloid cell leukemia sequence 1b0.053
acadlacyl-Coenzyme A dehydrogenase, long chain0.053
dynlrb1dynein, light chain, roadblock-type 10.053
got2aglutamic-oxaloacetic transaminase 2a, mitochondrial (aspartate aminotransferase 2)0.052
adipor1badiponectin receptor 1b0.052
immtinner membrane protein, mitochondrial (mitofilin)0.052
cdc42cell division cycle 420.052
orc1origin recognition complex, subunit 10.052
chia.2chitinase, acidic.20.051
ctsdcathepsin D0.051
eif3hbeukaryotic translation initiation factor 3, subunit H, b0.051
tnctenascin C0.050
atp1b1aATPase, Na+/K+ transporting, beta 1a polypeptide0.050
ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.050
eif4e1ceukaryotic translation initiation factor 4E family member 1c0.050
psma8proteasome (prosome, macropain) subunit, alpha type, 80.049
ctsccathepsin C0.049
psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.049
acaa2acetyl-CoA acyltransferase 20.049
rangap1Ran GTPase activating protein 10.049
hmgb1ahigh-mobility group box 1a0.049
trim33tripartite motif-containing 330.049
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Pi3K92ECG4141 gene product from transcript CG4141-RB1.000
EcREcdysone receptor0.993
Sir2CG5216 gene product from transcript CG5216-RA0.948
Atg8aAutophagy-specific gene 8a0.946
G-salpha60AG protein salpha 60A0.930
TorTarget of rapamycin0.925
CG11347CG11347 gene product from transcript CG11347-RE0.923
InRInsulin-like receptor0.918
Akt1CG4006 gene product from transcript CG4006-RA0.909
RhebCG1081 gene product from transcript CG1081-RA0.906
Prosbeta1Proteasome beta1 subunit0.881
Fmr1CG6203 gene product from transcript CG6203-RC0.881
SNF1ASNF1A/AMP-activated protein kinase0.871
p53CG33336 gene product from transcript CG33336-RB0.852
awdabnormal wing discs0.826
Pros26.4Proteasome 26S subunit subunit 4 ATPase0.817
Rho1CG8416 gene product from transcript CG8416-RB0.813
Rpn9CG10230 gene product from transcript CG10230-RB0.807
cpacapping protein alpha0.806
RecQ4CG7487 gene product from transcript CG7487-RA0.791
phlpole hole0.779
Atg18Autophagy-specific gene 180.768
CG1347CG1347 gene product from transcript CG1347-RB0.764
SosSon of sevenless0.756
dcodiscs overgrown0.746
Ras85DRas oncogene at 85D0.744
Rpt1CG1341 gene product from transcript CG1341-RA0.742
CSN5COP9 complex homolog subunit 50.741
Rpn11CG18174 gene product from transcript CG18174-RA0.740
MadMothers against dpp0.732
Rab1Rab-protein 10.721
Atg2Autophagy-specific gene 20.700
CG12321CG12321 gene product from transcript CG12321-RA0.684
Pi3K59FPhosphotidylinositol 3 kinase 59F0.683
piepineapple eye0.682
Rpt3CG16916 gene product from transcript CG16916-RA0.675
Nup154Nucleoporin 1540.672
Top1Topoisomerase 10.667
B52CG10851 gene product from transcript CG10851-RB0.657
rapretina aberrant in pattern0.655
Cip4CG15015 gene product from transcript CG15015-RA0.655
Cyp9f2CG11466 gene product from transcript CG11466-RB0.648
StamSignal transducing adaptor molecule0.644
sec15CG7034 gene product from transcript CG7034-RA0.641
rictorrapamycin-insensitive companion of Tor0.641
Syx7Syntaxin 70.627
Vps16AVacuolar protein sorting 16A0.623
Prosalpha5Proteasome alpha5 subunit0.621
S6kRPS6-p70-protein kinase0.618
Prosbeta2Proteasome beta2 subunit0.618
Atg6Autophagy-specific gene 60.617
Ugt35aUDP-glycosyltransferase 35a0.615
eIF-4EEukaryotic initiation factor 4E0.611
MntCG13316 gene product from transcript CG13316-RD0.610
Prosbeta3Proteasome beta3 subunit0.605
Rpn2CG11888 gene product from transcript CG11888-RA0.605
RASSF8CG5053 gene product from transcript CG5053-RA0.601
Pros29Proteasome 29kD subunit0.598
PknProtein kinase related to protein kinase N0.595
Ada2bCG9638 gene product from transcript CG9638-RA0.595
cenG1Acentaurin gamma 1A0.595
LanALaminin A0.588
Sox14Sox box protein 140.584
Top2Topoisomerase 20.583
EgfrEpidermal growth factor receptor0.577
Jafrac1thioredoxin peroxidase 10.568
RagACG11968 gene product from transcript CG11968-RA0.565
Ca-P60ACalcium ATPase at 60A0.561
mspsmini spindles0.560
RpS20Ribosomal protein S200.557
CG32479CG32479 gene product from transcript CG32479-RA0.541
CycBCyclin B0.540
Itp-r83AInositol 1,4,5,-tris-phosphate receptor0.534
plexBplexin B0.524
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Acadlacyl-Coenzyme A dehydrogenase, long-chain0.847
Decr12,4-dienoyl CoA reductase 1, mitochondrial0.842
Psma5proteasome (prosome, macropain) subunit, alpha type 50.792
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.783
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.731
Cyp2b1cytochrome P450, family 2, subfamily b, polypeptide 10.726
Ech1enoyl coenzyme A hydratase 1, peroxisomal0.713
Psma3proteasome (prosome, macropain) subunit, alpha type 30.710
Acaa2acetyl-Coenzyme A acyltransferase 20.660
Psmb3proteasome (prosome, macropain) subunit, beta type 30.646
Pebp1phosphatidylethanolamine binding protein 10.636
Gstm1glutathione S-transferase mu 10.634
Hk1hexokinase 10.633
Apobapolipoprotein B0.625
Kmokynurenine 3-monooxygenase (kynurenine 3-hydroxylase)0.608
Ctsl1cathepsin L10.587
Ugt1a6UDP glucuronosyltransferase 1 family, polypeptide A60.584
Cyp3a18cytochrome P450, family 3, subfamily a, polypeptide 180.577
Mapre1microtubule-associated protein, RP/EB family, member 10.555
Ppm1aprotein phosphatase 1A, magnesium dependent, alpha isoform0.547
Lamp2lysosomal-associated membrane protein 20.542
Acadvlacyl-Coenzyme A dehydrogenase, very long chain0.520
Cyp2d4cytochrome P450, family 2, subfamily d, polypeptide 40.517
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.516
Dnm1ldynamin 1-like0.506
Psmb4proteasome (prosome, macropain) subunit, beta type 40.488
Suclg1succinate-CoA ligase, alpha subunit0.482
Rab1RAB1, member RAS oncogene family0.470
Papolapoly (A) polymerase alpha0.465
Ppp2caprotein phosphatase 2, catalytic subunit, alpha isoform0.458
Casp3caspase 30.447
Etfaelectron-transfer-flavoprotein, alpha polypeptide0.444
Tap2transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)0.443
Psma7proteasome (prosome, macropain) subunit, alpha type 70.442
LOC293989cytochrome P450-like0.442
Acox1acyl-Coenzyme A oxidase 1, palmitoyl0.437
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.437
Acadmacyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain0.434
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.429
Dnajc5DnaJ (Hsp40) homolog, subfamily C, member 50.429
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.420
Hadhbhydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit0.414
Eif5eukaryotic translation initiation factor 50.412
Mgst2microsomal glutathione S-transferase 20.407
Exoc5exocyst complex component 50.400
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)0.397
Cyp4a3cytochrome P450, family 4, subfamily a, polypeptide 30.390
Acat1acetyl-coenzyme A acetyltransferase 10.388
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.384
Flt1FMS-related tyrosine kinase 10.382
Hsd17b4hydroxysteroid (17-beta) dehydrogenase 40.380
Slc25a20solute carrier family 25 (carnitine/acylcarnitine translocase), member 200.380
Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 20.380
Klf6Kruppel-like factor 60.371
Acadsacyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain0.370
Anxa2annexin A20.367
LOC494499LOC494499 protein0.366
Ces1ccarboxylesterase 1C0.363
Ifitm3interferon induced transmembrane protein 30.358
Mgst1microsomal glutathione S-transferase 10.354
Cpt2carnitine palmitoyltransferase 20.353
Gabrg1gamma-aminobutyric acid (GABA) A receptor, gamma 10.352
Pros1protein S (alpha)0.351
Etfdhelectron-transferring-flavoprotein dehydrogenase0.351
Abcc2ATP-binding cassette, subfamily C (CFTR/MRP), member 20.348
Acot2acyl-CoA thioesterase 20.346
Pls3plastin 3 (T-isoform)0.339
Ntrk1neurotrophic tyrosine kinase, receptor, type 10.337
Ucp2uncoupling protein 2 (mitochondrial, proton carrier)0.337
Hmgcs23-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)0.336
NsfN-ethylmaleimide-sensitive factor0.334
Gria2glutamate receptor, ionotropic, AMPA 20.331
Cyp4a2cytochrome P450, family 4, subfamily a, polypeptide 20.329
Gsta5glutathione S-transferase Yc2 subunit0.327
Prdx1peroxiredoxin 10.325
Myo1bmyosin Ib0.321
Ccnd3cyclin D30.314
Crotcarnitine O-octanoyltransferase0.310
Tpm4tropomyosin 40.307
Cmklr1chemokine-like receptor 10.306
Pck1phosphoenolpyruvate carboxykinase 1 (soluble)0.305
Lman1lectin, mannose-binding, 10.303
Psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.294
Cyp2c22cytochrome P450, family 2, subfamily c, polypeptide 220.293
Cox4i1cytochrome c oxidase subunit IV isoform 10.292
Dnaja1DnaJ (Hsp40) homolog, subfamily A, member 10.290
Rab11aRAB11a, member RAS oncogene family0.289
Cyp4a10cytochrome P450, family 4, subfamily a, polypeptide 100.288
Ftlferritin, light polypeptide0.287
Adaradenosine deaminase, RNA-specific0.286
Pik3cdphosphoinositide-3-kinase, catalytic, delta polypeptide0.284
Gdi2GDP dissociation inhibitor 20.274
Cyp2b15cytochrome P450, family 2, subfamily b, polypeptide 150.273
Flnbfilamin, beta0.272
Pdia4protein disulfide isomerase family A, member 40.272
Nae1NEDD8 activating enzyme E1 subunit 10.271
B2mbeta-2 microglobulin0.269
Ces1ecarboxylesterase 1E0.268
Cyp2b2cytochrome P450, family 2, subfamily b, polypeptide 20.267
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism