The network for 'regulation of mitotic metaphase anaphase transition' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of mitotic metaphase anaphase transition

Any process that modulates the frequency, rate or extent of the onset of anaphase (chromosome movement) in the mitotic cell cycle.

NameDescriptionProbabilityFunc Analog Organism
rnr-1Protein RNR-10.435
knl-1Protein KNL-10.365
mcm-2Protein MCM-20.365
ZK507.6Protein ZK507.60.173
hcp-1Protein HCP-10.163
hsr-9Protein HSR-90.134
CELE_C24H12.5Protein C24H12.50.128
R11A8.7Protein R11A8.70.128
flh-1Protein FLH-10.123
spdl-1Protein SPDL-10.121
dsh-2Protein DSH-20.115
bub-1Protein BUB-10.114
npp-11Protein NPP-110.114
his-45Protein HIS-450.113
gpr-2Protein GPR-20.107
brc-1Protein BRC-10.106
mcm-7Protein MCM-70.103
hcp-2Protein HCP-20.085
cyb-3Protein CYB-30.085
sel-12Protein SEL-120.083
pcn-1Protein PCN-10.081
taf-5Protein TAF-50.078
rod-1Protein ROD-10.066
air-2Protein AIR-20.063
puf-6Protein PUF-60.063
math-33Protein MATH-330.063
T08A11.2Protein T08A11.20.058
bmk-1Protein BMK-10.055
his-32Protein HIS-320.055
imb-2Protein IMB-20.054
cdl-1Protein CDL-10.054
pri-2Protein PRI-20.053
mcm-5Protein MCM-50.053
CELE_C25A1.1Protein C25A1.10.049
T28D9.4Protein T28D9.40.047
let-502Protein LET-5020.046
cyk-4Protein CYK-40.041
sun-1Protein SUN-10.037
mat-3Protein MAT-30.031
T08B2.11Protein T08B2.110.029
CELE_K08F4.1Protein K08F4.10.027
lin-9Protein LIN-90.027
F44E2.8Protein F44E2.80.026
T22F3.2Protein T22F3.20.024
klp-19Protein KLP-190.024
him-10Protein HIM-100.024
npp-3Protein NPP-30.022
prp-8Protein PRP-80.020
npp-7Protein NPP-70.019
rfc-2Protein RFC-20.017
hcp-6Protein HCP-60.017
trr-1Protein TRR-10.017
T26A5.5Protein T26A5.50.017
zen-4Protein ZEN-40.017
oma-1Protein OMA-10.017
mcm-3Protein MCM-30.016
knl-3Protein KNL-30.016
zyg-9Protein ZYG-90.016
attf-2Protein ATTF-20.015
rpa-2Protein RPA-20.015
his-42Protein HIS-420.015
T19H12.2Protein T19H12.20.015
icp-1Protein ICP-10.014
lmn-1Protein LMN-10.014
gyg-2Protein GYG-20.013
gck-1Protein GCK-10.013
skp-1Protein SKP-10.013
toe-2Protein TOE-20.012
CELE_B0238.9Protein B0238.90.012
pos-1Protein POS-10.012
Y47D3A.29Protein Y47D3A.290.012
gpr-1Protein GPR-10.012
rfc-4Protein RFC-40.011
his-2Protein HIS-20.011
emb-27Protein EMB-270.011
CELE_C39E9.12Protein C39E9.120.011
panl-2Protein PANL-20.011
ima-3Protein IMA-30.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
CycBCyclin B0.884
CycACyclin A0.815
BubR1Bub1-related kinase0.666
gwlgreatwall0.526
ncdnon-claret disjunctional0.521
IswiImitation SWI0.501
ChroChromator0.409
Mcm10Sensitized chromosome inheritance modifier 190.367
cavcaravaggio0.364
cdc16CG6759 gene product from transcript CG6759-RA0.351
SseSeparase0.242
cidcentromere identifier0.226
dupdouble parked0.222
thrthree rows0.200
aslasterless0.196
Spc105RSpc105-related0.189
bratbrain tumor0.186
SMC2CG10212 gene product from transcript CG10212-RA0.183
tefutelomere fusion0.178
cmetCENP-meta0.165
idaimaginal discs arrested0.160
Cap-GCG34438 gene product from transcript CG34438-RF0.151
Klp61FKinesin-like protein at 61F0.146
cdc2CG5363 gene product from transcript CG5363-RA0.143
SAKSak kinase0.137
nodno distributive disjunction0.136
nbsCG6754 gene product from transcript CG6754-RC0.122
Bj1Bj1 protein0.119
CG9772CG9772 gene product from transcript CG9772-RB0.119
Vap-33-1CG5014 gene product from transcript CG5014-RB0.115
hpohippo0.110
pimpimples0.106
msb1lCG10364 gene product from transcript CG10364-RA0.097
borrborealin-related0.084
aspabnormal spindle0.083
MybMyb oncogene-like0.079
stgstring0.078
poloCG12306 gene product from transcript CG12306-RA0.077
alphaTub67Calpha-Tubulin at 67C0.077
KP78bCG17216 gene product from transcript CG17216-RB0.076
marsCG17064 gene product from transcript CG17064-RB0.073
Kmn1kinetochore Mis12-Ndc80 network component 10.068
cdc23CG2508 gene product from transcript CG2508-RA0.067
Rpd3CG7471 gene product from transcript CG7471-RA0.066
Cks30ACyclin-dependent kinase subunit 30A0.066
NiPp1Nuclear inhibitor of Protein phosphatase 10.065
SMC1CG6057 gene product from transcript CG6057-RA0.062
DrefDNA replication-related element factor0.060
scrascraps0.059
flflfalafel0.059
Cks85ACyclin-dependent kinase subunit 85A0.058
mspsmini spindles0.057
Cenp-CCG31258 gene product from transcript CG31258-RA0.054
piepineapple eye0.046
fzyfizzy0.045
Cdc37CG12019 gene product from transcript CG12019-RA0.045
pavpavarotti0.045
tra2transformer 20.043
betaTub60Dbeta-Tubulin at 60D0.041
mus304mutagen-sensitive 3040.041
ruxroughex0.040
DNApol-alpha60DNA polymerase alpha 60kD0.040
NELF-BCG32721 gene product from transcript CG32721-RA0.039
bambag of marbles0.038
Su(H)Suppressor of Hairless0.037
Cdc27CG8610 gene product from transcript CG8610-RA0.037
dhddeadhead0.037
DetDeterin0.037
prodproliferation disrupter0.037
rodrough deal0.036
kukkugelkern0.036
shtdshattered0.035
Orc2Origin recognition complex subunit 20.035
ldslodestar0.035
dapdacapo0.034
CG7288CG7288 gene product from transcript CG7288-RA0.034
vtdverthandi0.034
jubAjuba LIM protein0.033
CycB3Cyclin B30.033
eastenhanced adult sensory threshold0.033
Ndc80CG9938 gene product from transcript CG9938-RA0.033
Pp1-87BProtein phosphatase 1 at 87B0.031
Trf4-1CG11265 gene product from transcript CG11265-RE0.031
Taspase1Taspase 10.030
Grip75CG6176 gene product from transcript CG6176-RA0.030
Rab23CG2108 gene product from transcript CG2108-RA0.029
CG6439CG6439 gene product from transcript CG6439-RA0.029
Rpb4CG33520 gene product from transcript CG33520-RF0.029
CG7564CG7564 gene product from transcript CG7564-RA0.028
ballballchen0.028
CG42569CG42569 gene product from transcript CG42569-RA0.027
pitaCG3941 gene product from transcript CG3941-RA0.027
CG5872CG5872 gene product from transcript CG5872-RA0.027
CG13625CG13625 gene product from transcript CG13625-RA0.027
IncenpInner centromere protein0.026
Dsor1Downstream of raf10.026
I-2Inhibitor-20.026
CG10722CG10722 gene product from transcript CG10722-RA0.026
Map60Microtubule-associated protein 600.026
mus301mutagen-sensitive 3010.025
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CDC20cell division cycle 20 homolog (S. cerevisiae)1.000
CDC27cell division cycle 27 homolog (S. cerevisiae)1.000
ANAPC4anaphase promoting complex subunit 41.000
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.999
CDK2cyclin-dependent kinase 20.999
CCNA2cyclin A20.999
CDC16cell division cycle 16 homolog (S. cerevisiae)0.999
CCNB1cyclin B10.997
ANAPC7anaphase promoting complex subunit 70.996
CDC23cell division cycle 23 homolog (S. cerevisiae)0.995
ANAPC1anaphase promoting complex subunit 10.989
BUB3budding uninhibited by benzimidazoles 3 homolog (yeast)0.987
ANAPC5anaphase promoting complex subunit 50.977
MAD2L1MAD2 mitotic arrest deficient-like 1 (yeast)0.963
PLK1polo-like kinase 10.910
RB1retinoblastoma 10.880
AURKBaurora kinase B0.844
ANAPC11anaphase promoting complex subunit 110.809
CDC26cell division cycle 26 homolog (S. cerevisiae)0.780
FBXO5F-box protein 50.773
BUB1budding uninhibited by benzimidazoles 1 homolog (yeast)0.674
CCT8chaperonin containing TCP1, subunit 8 (theta)0.632
SKP2S-phase kinase-associated protein 2 (p45)0.564
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme0.529
CBX5chromobox homolog 50.520
E2F1E2F transcription factor 10.515
PTTG1pituitary tumor-transforming 10.506
CDT1chromatin licensing and DNA replication factor 10.478
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.453
SKA1spindle and kinetochore associated complex subunit 10.428
CKS1BCDC28 protein kinase regulatory subunit 1B0.384
SMC3structural maintenance of chromosomes 30.329
NSMCE1non-SMC element 1 homolog (S. cerevisiae)0.261
STAG1stromal antigen 10.256
TFDP1transcription factor Dp-10.235
PPP2R5Cprotein phosphatase 2, regulatory subunit B', gamma0.229
H2AFXH2A histone family, member X0.215
CCNB2cyclin B20.209
MDC1mediator of DNA-damage checkpoint 10.187
SKA2spindle and kinetochore associated complex subunit 20.184
CDKN3cyclin-dependent kinase inhibitor 30.179
CHAF1Achromatin assembly factor 1, subunit A (p150)0.171
BRCA2breast cancer 2, early onset0.170
NDC80NDC80 homolog, kinetochore complex component (S. cerevisiae)0.166
TP53BP1tumor protein p53 binding protein 10.157
CLSPNclaspin0.157
SKA3spindle and kinetochore associated complex subunit 30.145
DOT1LDOT1-like, histone H3 methyltransferase (S. cerevisiae)0.143
RBL2retinoblastoma-like 2 (p130)0.137
NEK2NIMA (never in mitosis gene a)-related kinase 20.118
CKS2CDC28 protein kinase regulatory subunit 20.103
CREBBPCREB binding protein0.098
INCENPinner centromere protein antigens 135/155kDa0.096
PPP2R2Aprotein phosphatase 2, regulatory subunit B, alpha0.095
BIRC5baculoviral IAP repeat containing 50.095
NEK9NIMA (never in mitosis gene a)- related kinase 90.090
RBBP8retinoblastoma binding protein 80.089
USP7ubiquitin specific peptidase 7 (herpes virus-associated)0.086
UHRF1ubiquitin-like with PHD and ring finger domains 10.086
TINF2TERF1 (TRF1)-interacting nuclear factor 20.081
SMC6structural maintenance of chromosomes 60.079
FOXM1forkhead box M10.079
ATRXalpha thalassemia/mental retardation syndrome X-linked0.075
UHRF2ubiquitin-like with PHD and ring finger domains 20.073
RAD21RAD21 homolog (S. pombe)0.073
PRC1protein regulator of cytokinesis 10.073
CDCA8cell division cycle associated 80.072
PPP2R5Aprotein phosphatase 2, regulatory subunit B', alpha0.071
MOBKL3MOB1, Mps One Binder kinase activator-like 3 (yeast)0.069
ZNF207zinc finger protein 2070.069
ORC1origin recognition complex, subunit 10.068
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.068
MYBL2v-myb myeloblastosis viral oncogene homolog (avian)-like 20.067
CHAF1Bchromatin assembly factor 1, subunit B (p60)0.065
UBE2Cubiquitin-conjugating enzyme E2C0.064
PXNpaxillin0.062
MYST1MYST histone acetyltransferase 10.060
RBL1retinoblastoma-like 1 (p107)0.060
PPP2R1Bprotein phosphatase 2, regulatory subunit A, beta0.058
AXIN2axin 20.058
KIF18Akinesin family member 18A0.058
ANAPC16anaphase promoting complex subunit 160.058
MED1mediator complex subunit 10.055
SGOL1shugoshin-like 1 (S. pombe)0.055
FXR2fragile X mental retardation, autosomal homolog 20.054
MDM2Mdm2 p53 binding protein homolog (mouse)0.054
ZWINTZW10 interactor0.054
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.053
HDAC1histone deacetylase 10.051
CCND1cyclin D10.050
MAD2L2MAD2 mitotic arrest deficient-like 2 (yeast)0.050
PRRC2Cproline-rich coiled-coil 2C0.049
KPNA3karyopherin alpha 3 (importin alpha 4)0.048
E2F4E2F transcription factor 4, p107/p130-binding0.048
TTKTTK protein kinase0.047
SIRT2sirtuin 20.047
BTBD10BTB (POZ) domain containing 100.046
TNKStankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase0.046
HERC2hect domain and RLD 20.046
SMAD2SMAD family member 20.045
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 530.984
Ctnnb1catenin (cadherin associated protein), beta 10.730
Ccnb1cyclin B10.607
Cdk1cyclin-dependent kinase 10.335
Kif22kinesin family member 220.306
Brca1breast cancer 10.180
Ccna2cyclin A20.125
Mki67antigen identified by monoclonal antibody Ki 670.125
Kif20akinesin family member 20A0.119
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.116
Ptenphosphatase and tensin homolog0.114
Cdk2cyclin-dependent kinase 20.102
Sgol2shugoshin-like 2 (S. pombe)0.100
Birc5baculoviral IAP repeat-containing 50.099
Ube2cubiquitin-conjugating enzyme E2C0.089
Ccnb2cyclin B20.081
Hmmrhyaluronan mediated motility receptor (RHAMM)0.076
Prc1protein regulator of cytokinesis 10.069
Ccnfcyclin F0.057
Cdkn1bcyclin-dependent kinase inhibitor 1B0.049
Mdm2transformed mouse 3T3 cell double minute 20.047
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.045
Ccne1cyclin E10.044
Msh2mutS homolog 2 (E. coli)0.042
Apcadenomatosis polyposis coli0.041
H2afxH2A histone family, member X0.037
Kif2ckinesin family member 2C0.036
Psen1presenilin 10.032
Rrm2ribonucleotide reductase M20.028
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.026
Kif11kinesin family member 110.026
Melkmaternal embryonic leucine zipper kinase0.026
Aurkbaurora kinase B0.025
Acdadrenocortical dysplasia0.025
Aurkaaurora kinase A0.025
Cdca8cell division cycle associated 80.024
Lmnb1lamin B10.024
C330027C09RikRIKEN cDNA C330027C09 gene0.024
Spag5sperm associated antigen 50.023
Uhrf1ubiquitin-like, containing PHD and RING finger domains, 10.023
Kif4kinesin family member 40.022
Gsk3bglycogen synthase kinase 3 beta0.022
Rb1retinoblastoma 10.022
Sgol1shugoshin-like 1 (S. pombe)0.021
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.020
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.019
Plk1polo-like kinase 1 (Drosophila)0.019
Suz12suppressor of zeste 12 homolog (Drosophila)0.018
Axin1axin 10.018
Brca2breast cancer 20.018
Cdc25ccell division cycle 25 homolog C (S. pombe)0.018
Kif23kinesin family member 230.017
Lin9lin-9 homolog (C. elegans)0.017
Gtse1G two S phase expressed protein 10.016
Cenpecentromere protein E0.016
Cdca5cell division cycle associated 50.016
Trim59tripartite motif-containing 590.015
Ooepoocyte expressed protein homolog (dog)0.014
E2f1E2F transcription factor 10.014
Ckap2cytoskeleton associated protein 20.014
BrafBraf transforming gene0.014
Nek2NIMA (never in mitosis gene a)-related expressed kinase 20.014
Tmpothymopoietin0.013
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.013
Dlgap5discs, large (Drosophila) homolog-associated protein 50.013
E2f8E2F transcription factor 80.013
Cenpacentromere protein A0.013
Ect2ect2 oncogene0.013
Mis18bp1MIS18 binding protein 10.013
Rad51ap1RAD51 associated protein 10.012
Hmgb1high mobility group box 10.011
Kntc1kinetochore associated 10.011
Gsg2germ cell-specific gene 20.011
Cdk4cyclin-dependent kinase 40.011
2810417H13RikRIKEN cDNA 2810417H13 gene0.011
Ezh2enhancer of zeste homolog 2 (Drosophila)0.010
Trip13thyroid hormone receptor interactor 130.010
Chek1checkpoint kinase 1 homolog (S. pombe)0.010
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
CDC16Cdc16p0.998
CDC23Cdc23p0.981
DOC1Doc1p0.980
CDC27Cdc27p0.978
CDC20Cdc20p0.957
MAD2Mad2p0.954
SLK19Slk19p0.938
SLI15Sli15p0.921
SPC105Spc105p0.917
MTW1Mtw1p0.895
BUB3Bub3p0.871
PPH21Pph21p0.864
APC2Apc2p0.861
MND2Mnd2p0.831
CDC26Cdc26p0.796
CSE4Cse4p0.779
NSL1Nsl1p0.778
TID3Tid3p0.770
APC4Apc4p0.762
PPH22Pph22p0.734
CTF13Ctf13p0.724
DSN1Dsn1p0.698
SWM1Swm1p0.635
APC1Apc1p0.569
SMC4Smc4p0.557
MIF2Mif2p0.543
PPZ1Ppz1p0.466
MCM21Mcm21p0.437
HHF2Hhf2p0.429
MAD3Mad3p0.396
PDS1Pds1p0.387
RTS1Rts1p0.375
MPS1Mps1p0.374
PSH1Psh1p0.374
CDC55Cdc55p0.373
DAM1Dam1p0.372
KIP1Kip1p0.357
IML3Iml3p0.356
PIG2Pig2p0.351
BUB1Bub1p0.342
CHL4Chl4p0.328
APC5Apc5p0.310
CTF19Ctf19p0.306
SPC24Spc24p0.283
AME1Ame1p0.274
YPI1Ypi1p0.272
IPL1Ipl1p0.266
MAD1Mad1p0.253
CTF3Ctf3p0.208
CBF2Cbf2p0.195
OKP1Okp1p0.186
TIP41Tip41p0.144
YBP2Ybp2p0.133
CDH1Cdh1p0.128
NUF2Nuf2p0.128
APC9Apc9p0.122
CIN8Cin8p0.117
ASE1Ase1p0.110
SDS22Sds22p0.104
MCM22Mcm22p0.102
SMC2Smc2p0.095
NTO1Nto1p0.092
APC11Apc11p0.091
FMP48Fmp48p0.090
SMC6Smc6p0.085
NNF1Nnf1p0.081
BFA1Bfa1p0.081
ECO1Eco1p0.073
NSE1Nse1p0.070
SPC25Spc25p0.068
RAD24Rad24p0.068
GIP2Gip2p0.064
RDH54Rdh54p0.060
SMC5Smc5p0.058
CBF1Cbf1p0.057
ZDS2Zds2p0.056
GLG1Glg1p0.056
VIK1Vik1p0.051
KIC1Kic1p0.051
BRN1Brn1p0.048
NSE4Nse4p0.046
HTA1Hta1p0.045
NBL1Nbl1p0.044
ESP1Esp1p0.043
FIN1Fin1p0.041
MMS21Mms21p0.041
PSY4Psy4p0.040
DCC1Dcc1p0.038
CIN1Cin1p0.038
CHL1Chl1p0.037
PRP28Prp28p0.036
SPC110Spc110p0.036
PTI1Pti1p0.035
YKL075Chypothetical protein0.034
SCM3Scm3p0.032
SCC2Scc2p0.031
SRD1Srd1p0.030
SPO12Spo12p0.030
PCL10Pcl10p0.030
BIR1Bir1p0.029