The network for 'prevention of polyspermy' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

prevention of polyspermy

The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg.

NameDescriptionProbabilityFunc Analog Organism
C13G5.2Protein C13G5.20.024
thoc-3Protein THOC-30.024
tag-342Protein TAG-3420.023
Y5F2A.4Protein Y5F2A.40.022
C02B10.4Protein C02B10.40.019
C01G5.5Protein C01G5.50.018
F26A1.1Protein F26A1.10.017
C14B1.9Protein C14B1.90.017
Y54G9A.5Protein Y54G9A.50.017
C35D10.7Protein C35D10.70.016
CELE_Y110A2AR.1Protein Y110A2AR.10.016
pch-2Protein PCH-20.016
lin-54Protein LIN-540.016
vps-39Protein VPS-390.016
lgg-3Protein LGG-30.015
F26F4.5Protein F26F4.50.014
D2030.8Protein D2030.80.014
ZK287.7Protein ZK287.70.014
W03C9.2Protein W03C9.20.014
CELE_Y106G6H.16Protein Y106G6H.160.013
F38H4.10Protein F38H4.100.013
F21D5.2Protein F21D5.20.013
ZK328.4Protein ZK328.40.013
R05H5.3Protein R05H5.30.012
skpt-1Protein SKPT-10.012
T24H7.4Protein T24H7.40.012
CELE_W01G7.4Protein W01G7.40.011
taf-6.1Protein TAF-6.10.011
T21C9.13Protein T21C9.130.011
T24D1.2Protein T24D1.20.011
F55G1.6Protein F55G1.60.011
B0511.7Protein B0511.70.010
C48B4.7Protein C48B4.70.010
Y51F10.2Protein Y51F10.20.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
rtcd1RNA terminal phosphate cyclase domain 10.159
nr2f6anuclear receptor subfamily 2, group F, member 6a0.086
acsbg2acyl-CoA synthetase bubblegum family member 20.031
sept2septin 20.020
nudt9nudix (nucleoside diphosphate linked moiety X)-type motif 90.018
erfEts2 repressor factor0.017
abca12ATP-binding cassette, sub-family A (ABC1), member 120.016
celsr1acadherin EGF LAG seven-pass G-type receptor 1a0.015
grk5G protein-coupled receptor kinase 50.015
cntn2contactin 20.014
scamp2secretory carrier membrane protein 20.014
zfrzinc finger RNA binding protein0.014
rac1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.013
sf1splicing factor 10.013
acvr1lactivin A receptor, type I like0.013
gnaiaguanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a0.013
arpc5aactin related protein 2/3 complex, subunit 5A0.013
far1fatty acyl CoA reductase 10.012
rap1aRAP1A, member of RAS oncogene family0.012
ubinataxin-1 ubiquitin-like interacting protein0.012
ttc39ctetratricopeptide repeat domain 39C0.011
epas1aendothelial PAS domain protein 1a0.011
add1adducin 1 (alpha)0.011
alcambactivated leukocyte cell adhesion molecule b0.011
arhgap28Rho GTPase activating protein 280.010
eif3s10eukaryotic translation initiation factor 3, subunit 10 (theta)0.010
pobpartial optokinetic response b0.010
seh1lSEH1-like (S. cerevisiae)0.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Adam19a disintegrin and metallopeptidase domain 19 (meltrin beta)0.997
Adam15a disintegrin and metallopeptidase domain 15 (metargidin)0.880
Klf3Kruppel-like factor 3 (basic)0.751
Raver2ribonucleoprotein, PTB-binding 20.740
Tgfb2transforming growth factor, beta 20.725
Adam12a disintegrin and metallopeptidase domain 12 (meltrin alpha)0.615
Jag1jagged 10.591
Cxcr7chemokine (C-X-C motif) receptor 70.501
Egfrepidermal growth factor receptor0.446
Efnb2ephrin B20.443
Adam9a disintegrin and metallopeptidase domain 9 (meltrin gamma)0.377
Hey2hairy/enhancer-of-split related with YRPW motif 20.357
Grin2aglutamate receptor, ionotropic, NMDA2A (epsilon 1)0.215
Sos1son of sevenless homolog 1 (Drosophila)0.175
Adam17a disintegrin and metallopeptidase domain 170.171
Cd44CD44 antigen0.166
Cenpjcentromere protein J0.165
Hbegfheparin-binding EGF-like growth factor0.158
Il6stinterleukin 6 signal transducer0.154
Ptpn11protein tyrosine phosphatase, non-receptor type 110.150
Hif1ahypoxia inducible factor 1, alpha subunit0.145
Ntf3neurotrophin 30.139
Gata4GATA binding protein 40.122
Abp1amiloride binding protein 1 (amine oxidase, copper-containing)0.118
Raver1ribonucleoprotein, PTB-binding 10.115
Glipr2GLI pathogenesis-related 20.107
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.091
Foxc2forkhead box C20.081
Acracrosin prepropeptide0.080
Tm9sf3transmembrane 9 superfamily member 30.078
Gja1gap junction protein, alpha 10.077
Nr3c1nuclear receptor subfamily 3, group C, member 10.076
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.074
Vmn1r44vomeronasal 1 receptor 440.074
Lrrc58leucine rich repeat containing 580.073
Zp3zona pellucida glycoprotein 30.073
Efna1ephrin A10.073
Eea1early endosome antigen 10.072
Ovgp1oviductal glycoprotein 10.072
Il17reinterleukin 17 receptor E0.072
Chrna6cholinergic receptor, nicotinic, alpha polypeptide 60.068
Krtap5-1keratin associated protein 5-10.067
Mplmyeloproliferative leukemia virus oncogene0.066
Asah1N-acylsphingosine amidohydrolase 10.065
Syt7synaptotagmin VII0.064
Cuzd1CUB and zona pellucida-like domains 10.063
Sftpdsurfactant associated protein D0.062
Dnahc5dynein, axonemal, heavy chain 50.058
Adam3a disintegrin and metallopeptidase domain 3 (cyritestin)0.058
Btg4B-cell translocation gene 40.057
Slc6a2solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 20.056
Ptch2patched homolog 20.056
Grin2cglutamate receptor, ionotropic, NMDA2C (epsilon 3)0.055
Klf17Kruppel-like factor 170.052
Ggta1glycoprotein galactosyltransferase alpha 1, 30.052
Kcna6potassium voltage-gated channel, shaker-related, subfamily, member 60.052
Ccdc64coiled-coil domain containing 640.051
P4ha1procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide0.050
Gata6GATA binding protein 60.050
Tas1r1taste receptor, type 1, member 10.048
Kcnu1potassium channel, subfamily U, member 10.048
Krtap12-1keratin associated protein 12-10.048
Ltbp2latent transforming growth factor beta binding protein 20.047
Svs5seminal vesicle secretory protein 50.047
Cplx2complexin 20.046
Timm8a2translocase of inner mitochondrial membrane 8 homolog a2 (yeast)0.045
Olfr49olfactory receptor 490.045
Cyp11b2cytochrome P450, family 11, subfamily b, polypeptide 20.043
Npffneuropeptide FF-amide peptide precursor0.042
Muc5bmucin 5, subtype B, tracheobronchial0.041
Dmc1DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)0.041
Ifna2interferon alpha 20.041
Jupjunction plakoglobin0.040
Olfr1509olfactory receptor 15090.039
Plaurplasminogen activator, urokinase receptor0.039
Aff2AF4/FMR2 family, member 20.039
1810030J14RikRIKEN cDNA 1810030J14 gene0.038
Cacna1ecalcium channel, voltage-dependent, R type, alpha 1E subunit0.038
Guca2aguanylate cyclase activator 2a (guanylin)0.038
Ubxn10UBX domain protein 100.036
Mfi2antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.50.035
Gpr143G protein-coupled receptor 1430.035
Htra3HtrA serine peptidase 30.035
Adam4a disintegrin and metallopeptidase domain 40.034
Tcl1b1T-cell leukemia/lymphoma 1B, 10.034
Gnao1guanine nucleotide binding protein, alpha O0.034
Epha6Eph receptor A60.034
Ckap4cytoskeleton-associated protein 40.034
Ccl28chemokine (C-C motif) ligand 280.034
Mmp7matrix metallopeptidase 70.034
4930544G11RikRIKEN cDNA 4930544G11 gene0.033
Cd46CD46 antigen, complement regulatory protein0.033
Pa2g4proliferation-associated 2G40.033
Fndc7fibronectin type III domain containing 70.033
Reg3gregenerating islet-derived 3 gamma0.033
Grb2growth factor receptor bound protein 20.033
Bpil1bactericidal/permeability-increasing protein-like 10.032
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism