The network for 'regulation of developmental growth' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of developmental growth

Any process that modulates the frequency, rate or extent of developmental growth.

NameDescriptionProbabilityFunc Analog Organism
hlh-2Protein HLH-20.563
col-157Protein COL-1570.439
mlt-11Protein MLT-110.391
egl-18Protein EGL-180.378
pha-4Protein PHA-40.370
dim-1Protein DIM-10.364
rol-6Protein ROL-60.357
kgb-1Protein KGB-10.345
lrp-2Protein LRP-20.342
mes-3Protein MES-30.328
nhr-2Protein NHR-20.320
nhr-46Protein NHR-460.318
goa-1Protein GOA-10.318
egl-15Protein EGL-150.316
daf-4Protein DAF-40.311
daf-11Protein DAF-110.310
inx-13Protein INX-130.309
unc-62Protein UNC-620.302
swsn-2.1Protein SWSN-2.10.295
lin-35Protein LIN-350.294
glp-1Protein GLP-10.290
vab-3Protein VAB-30.286
sams-3Protein SAMS-30.285
lin-66Protein LIN-660.281
ceh-20Protein CEH-200.277
pyr-1Protein PYR-10.268
wrt-6Protein WRT-60.267
elt-6Protein ELT-60.267
egl-46Protein EGL-460.258
sma-1Protein SMA-10.257
mep-1Protein MEP-10.256
cacn-1Protein CACN-10.255
col-119Protein COL-1190.254
plc-1Protein PLC-10.245
pbs-7Protein PBS-70.243
itx-1Protein ITX-10.242
elo-6Protein ELO-60.241
ten-1Protein TEN-10.237
lrp-1Protein LRP-10.236
ldb-1Protein LDB-10.235
col-84Protein COL-840.234
elo-2Protein ELO-20.234
npp-7Protein NPP-70.232
msp-64Protein MSP-640.231
lev-8Protein LEV-80.230
egg-6Protein EGG-60.230
dkf-2Protein DKF-20.230
sdz-28Protein SDZ-280.228
nhr-66Protein NHR-660.228
che-1Protein CHE-10.228
unc-45Protein UNC-450.226
unc-68Protein UNC-680.225
hcp-3Protein HCP-30.225
lin-17Protein LIN-170.224
vav-1Protein VAV-10.223
unc-70Protein UNC-700.223
ina-1Protein INA-10.220
hda-3Protein HDA-30.215
egl-5Protein EGL-50.213
top-1Protein TOP-10.212
dre-1Protein DRE-10.208
noah-1Protein NOAH-10.207
msp-40Protein MSP-400.207
sams-1Protein SAMS-10.206
K04F10.7Protein K04F10.70.205
msp-10Protein MSP-100.202
cpsf-1Protein CPSF-10.202
bec-1Protein BEC-10.201
E02H1.1Protein E02H1.10.201
che-3Protein CHE-30.201
inx-12Protein INX-120.198
col-101Protein COL-1010.197
hpo-10Protein HPO-100.197
pbo-4Protein PBO-40.196
alg-1Protein ALG-10.196
col-38Protein COL-380.195
ran-5Protein RAN-50.195
sem-5Protein SEM-50.194
sqt-1Protein SQT-10.192
tni-1Protein TNI-10.191
F49E2.5Protein F49E2.50.190
vha-8Protein VHA-80.189
R03E1.2Protein R03E1.20.186
hsr-9Protein HSR-90.186
lmn-1Protein LMN-10.185
col-2Protein COL-20.184
mes-4Protein MES-40.184
xpo-1Protein XPO-10.184
col-133Protein COL-1330.183
tax-4Protein TAX-40.183
T08A11.2Protein T08A11.20.183
col-34Protein COL-340.182
sma-6Protein SMA-60.181
nac-1Protein NAC-10.181
col-159Protein COL-1590.181
sun-1Protein SUN-10.180
syg-1Protein SYG-10.180
sqv-5Protein SQV-50.179
anc-1Protein ANC-10.179
let-653Protein LET-6530.178
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
ptch2patched 20.566
pitx3paired-like homeodomain transcription factor 30.533
robo3roundabout homolog 30.455
smad1MAD homolog 1 (Drosophila)0.375
bmp2bbone morphogenetic protein 2b0.367
efnb2aephrin B2a0.367
fgfr1afibroblast growth factor receptor 1a0.316
tbx1T-box 10.312
cdh2cadherin 2, neuronal0.298
dag1dystroglycan 10.273
alcambactivated leukocyte cell adhesion molecule b0.206
ret1receptor tyrosine kinase0.203
limk2LIM domain kinase 20.190
s1pr2sphingosine-1-phosphate receptor 20.185
robo2roundabout homolog 20.174
gli1GLI-Kruppel family member 10.173
jag2jagged 20.167
aldocbaldolase C, fructose-bisphosphate, b0.149
metmet proto-oncogene (hepatocyte growth factor receptor)0.148
plxnb2aplexin b2a0.143
foxd3forkhead box D30.141
fgfr3fibroblast growth factor receptor 30.138
six4bsine oculis homeobox homolog 4b0.134
notch2notch homolog 20.131
lhx2bLIM homeobox 2b0.127
llgl2lethal giant larvae homolog 2 (Drosophila)0.125
hnf4ahepatocyte nuclear factor 4, alpha0.123
foxi1forkhead box I10.122
hey1hairy/enhancer-of-split related with YRPW motif 10.121
wnt11rwingless-type MMTV integration site family, member 11, related0.121
ptpraprotein tyrosine phosphatase, receptor type, A0.117
bocbrother of CDO0.112
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.104
igfbp3insulin-like growth factor binding protein 30.101
bmp2abone morphogenetic protein 2a0.099
pax8paired box gene 80.099
pea3ETS-domain transcription factor pea30.097
nrg2aneuregulin 2a0.093
jag1bjagged 1b0.093
shhbsonic hedgehog b0.089
phox2bpaired-like homeobox 2b0.087
tshbthyroid stimulating hormone, beta subunit0.087
amotl2aangiomotin like 2a0.086
myf5myogenic factor 50.085
myod1myogenic differentiation 10.084
pomcaproopiomelanocortin a0.083
gle1GLE1 RNA export mediator homolog (yeast)0.080
klf4aKruppel-like transcription factor 4a0.077
ihhaIndian hedgehog homolog a0.077
cadm2acell adhesion molecule 2a0.077
lmnalamin A0.076
fzd7afrizzled homolog 7a0.075
cacnb1calcium channel, voltage-dependent, beta 1 subunit0.074
fgf19fibroblast growth factor 190.074
krml2.2Kreisler (mouse) maf-related leucine zipper homolog 2.20.074
st8sia2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 20.071
pcdh8protocadherin 80.071
mapk3mitogen-activated protein kinase 30.070
sall1asal-like 1a (Drosophila)0.070
wnt3awingless-type MMTV integration site family, member 3A0.069
atp6v1baATPase, H+ transporting, lysosomal, V1 subunit B, member a0.069
sfrp5secreted frizzled-related protein 50.066
mapk1mitogen-activated protein kinase 10.066
axin2axin 2 (conductin, axil)0.065
gro2groucho 20.064
ptk2.1protein tyrosine kinase 2a0.063
smosmoothened homolog (Drosophila)0.062
hs6st2heparan sulfate 6-O-sulfotransferase 20.062
kpna4karyopherin alpha 4 (importin alpha 3)0.060
rc3rabconnectin 30.059
kif5bbkinesin family member 5B, b0.058
sox9bSRY-box containing gene 9b0.057
fgfr4fibroblast growth factor receptor 40.057
igf2binsulin-like growth factor 2b0.057
nadl1.2neural adhesion molecule L1.20.057
tcf7transcription factor 7 (T-cell specific, HMG-box)0.057
traf4atnf receptor-associated factor 4a0.057
tbx2bT-box 2b0.056
nrp2bneuropilin 2b0.055
notch3notch homolog 30.055
gpiaglucose phosphate isomerase a0.054
bop1block of proliferation 10.054
arnt2aryl hydrocarbon receptor nuclear translocator 20.054
nrp1aneuropilin 1a0.053
ndr2nodal-related 20.053
onecut1one cut domain, family member 10.053
tbx20T-box 200.053
lratblecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)0.052
ptenaphosphatase and tensin homolog A0.052
epb4.1l4erythrocyte protein band 4.1-like 40.052
otx1aorthodenticle homolog 1a0.051
tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.051
LOC565459tight junction protein ZO-1-like0.050
igf1rainsulin-like growth factor 1a receptor0.050
wnt10awingless-type MMTV integration site family, member 10a0.050
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Akt1CG4006 gene product from transcript CG4006-RA0.997
Rac1CG2248 gene product from transcript CG2248-RA0.994
Pi3K92ECG4141 gene product from transcript CG4141-RB0.994
MadMothers against dpp0.991
eIF-4EEukaryotic initiation factor 4E0.986
Ras85DRas oncogene at 85D0.986
RhebCG1081 gene product from transcript CG1081-RA0.975
EcREcdysone receptor0.968
PtenCG5671 gene product from transcript CG5671-RB0.965
S6kRPS6-p70-protein kinase0.952
chicoCG5686 gene product from transcript CG5686-RB0.938
Vap-33-1CG5014 gene product from transcript CG5014-RB0.929
Pk61CProtein kinase 61C0.916
Stat92ESignal-transducer and activator of transcription protein at 92E0.907
InRInsulin-like receptor0.906
neuroliginCG13772 gene product from transcript CG13772-RA0.890
witwishful thinking0.887
Nrx-IVNeurexin IV0.886
G-oalpha47AG protein oalpha 47A0.884
slmbsupernumerary limbs0.883
CspCysteine string protein0.876
SmoxSmad on X0.870
l(2)gllethal (2) giant larvae0.870
stanstarry night0.869
jebjelly belly0.866
drkdownstream of receptor kinase0.848
DadDaughters against dpp0.846
CkIIalphaCasein kinase II alpha subunit0.844
LanB2Laminin B20.725
Gp150CG5820 gene product from transcript CG5820-RA0.718
LnkCG17367 gene product from transcript CG17367-RC0.716
CycDCyclin D0.715
RhoGEF2CG9635 gene product from transcript CG9635-RF0.689
14-3-3epsilonCG31196 gene product from transcript CG31196-RA0.688
AcslAcyl-CoA synthetase long-chain0.662
phlpole hole0.658
grimCG4345 gene product from transcript CG4345-RA0.600
Atg1Autophagy-specific gene 10.585
par-6CG5884 gene product from transcript CG5884-RA0.581
shotshort stop0.580
Hsc70-4Heat shock protein cognate 40.576
cicubitus interruptus0.576
ebiCG4063 gene product from transcript CG4063-RA0.574
Sema-2aCG4700 gene product from transcript CG4700-RC0.565
slp1sloppy paired 10.559
Ilp2Insulin-like peptide 20.554
CycECyclin E0.543
bratbrain tumor0.543
Arp66BActin-related protein 66B0.541
Cg25CCollagen type IV0.526
TorTarget of rapamycin0.517
MED19Mediator complex subunit 190.504
Eip74EFEcdysone-induced protein 74EF0.502
Nf1Neurofibromin 10.498
fkhfork head0.486
SbfSET domain binding factor0.483
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.894
CREBBPCREB binding protein0.562
SMAD3SMAD family member 30.470
EP300E1A binding protein p3000.431
FGFR2fibroblast growth factor receptor 20.419
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.398
EGFRepidermal growth factor receptor0.392
SMAD4SMAD family member 40.308
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.297
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.247
ESR1estrogen receptor 10.219
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.178
ATXN1ataxin 10.156
YAP1Yes-associated protein 10.154
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.149
LATlinker for activation of T cells0.148
DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked0.143
GSK3Bglycogen synthase kinase 3 beta0.137
CCT3chaperonin containing TCP1, subunit 3 (gamma)0.133
SMAD2SMAD family member 20.133
BADBCL2-associated agonist of cell death0.131
PDIA3protein disulfide isomerase family A, member 30.123
MBNL1muscleblind-like (Drosophila)0.120
BMI1BMI1 polycomb ring finger oncogene0.118
RB1retinoblastoma 10.118
SCHIP1schwannomin interacting protein 10.114
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.113
SIRT1sirtuin 10.105
RASSF5Ras association (RalGDS/AF-6) domain family member 50.103
H2AFXH2A histone family, member X0.102
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.102
ATF2activating transcription factor 20.098
ZMYND11zinc finger, MYND-type containing 110.095
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.094
KCNJ4potassium inwardly-rectifying channel, subfamily J, member 40.094
INSRinsulin receptor0.092
ABCA1ATP-binding cassette, sub-family A (ABC1), member 10.085
PUM2pumilio homolog 2 (Drosophila)0.082
SRSF10serine/arginine-rich splicing factor 100.082
TP53tumor protein p530.081
MOBKL1BMOB1, Mps One Binder kinase activator-like 1B (yeast)0.078
PPP1R12Aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.078
CCT7chaperonin containing TCP1, subunit 7 (eta)0.077
CAV1caveolin 1, caveolae protein, 22kDa0.076
WIPF1WAS/WASL interacting protein family, member 10.076
STK4serine/threonine kinase 40.075
SPTBN1spectrin, beta, non-erythrocytic 10.075
PRKCZprotein kinase C, zeta0.073
SKILSKI-like oncogene0.073
FGF1fibroblast growth factor 1 (acidic)0.073
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.072
PRMT1protein arginine methyltransferase 10.071
SNW1SNW domain containing 10.069
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.068
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A0.068
ARandrogen receptor0.068
TNRC6Atrinucleotide repeat containing 6A0.067
CREB1cAMP responsive element binding protein 10.064
FLNAfilamin A, alpha0.064
GRB2growth factor receptor-bound protein 20.063
PABPC1poly(A) binding protein, cytoplasmic 10.062
TRIM37tripartite motif containing 370.062
EEF1Geukaryotic translation elongation factor 1 gamma0.061
ITGB2integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)0.061
WASLWiskott-Aldrich syndrome-like0.060
SHC1SHC (Src homology 2 domain containing) transforming protein 10.058
AKT1v-akt murine thymoma viral oncogene homolog 10.054
TPT1tumor protein, translationally-controlled 10.054
HDAC4histone deacetylase 40.053
NCOA6nuclear receptor coactivator 60.053
RPL34ribosomal protein L340.052
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)0.051
RPL27ribosomal protein L270.051
SMURF2SMAD specific E3 ubiquitin protein ligase 20.051
TBX5T-box 50.051
VEGFAvascular endothelial growth factor A0.050
ADNPactivity-dependent neuroprotector homeobox0.050
DHX9DEAH (Asp-Glu-Ala-His) box polypeptide 90.050
SMAD5SMAD family member 50.050
CAND1cullin-associated and neddylation-dissociated 10.048
NCOR1nuclear receptor corepressor 10.048
SYKspleen tyrosine kinase0.047
ZFYVE9zinc finger, FYVE domain containing 90.047
HSPA9heat shock 70kDa protein 9 (mortalin)0.045
TBL1XR1transducin (beta)-like 1 X-linked receptor 10.045
CAPRIN1cell cycle associated protein 10.045
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.044
HNF4Ahepatocyte nuclear factor 4, alpha0.044
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.044
DAAM1dishevelled associated activator of morphogenesis 10.044
NCOR2nuclear receptor corepressor 20.043
SP1Sp1 transcription factor0.043
PDIA4protein disulfide isomerase family A, member 40.043
PPARAperoxisome proliferator-activated receptor alpha0.042
FEZ1fasciculation and elongation protein zeta 1 (zygin I)0.041
BPTFbromodomain PHD finger transcription factor0.041
ATRXalpha thalassemia/mental retardation syndrome X-linked0.041
ACTR2ARP2 actin-related protein 2 homolog (yeast)0.040
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.040
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Dlg4discs, large homolog 4 (Drosophila)0.300
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.198
Prrx1paired related homeobox 10.184
Nrxn1neurexin 10.181
Camkk2calcium/calmodulin-dependent protein kinase kinase 2, beta0.137
Grin2aglutamate receptor, ionotropic, N-methyl D-aspartate 2A0.129
Camk2acalcium/calmodulin-dependent protein kinase II alpha0.121
Olr287olfactory receptor 2870.119
Jak2Janus kinase 20.119
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.112
Syn1synapsin I0.111
Fgfr2fibroblast growth factor receptor 20.109
Cfbcomplement factor B0.105
Grin1glutamate receptor, ionotropic, N-methyl D-aspartate 10.100
Cyp51cytochrome P450, family 510.100
Magi2membrane associated guanylate kinase, WW and PDZ domain containing 20.095
Gabrb3gamma-aminobutyric acid (GABA) A receptor, beta 30.095
Hmgcs13-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)0.092
Kcnj11potassium inwardly rectifying channel, subfamily J, member 110.076
Nedd4neural precursor cell expressed, developmentally down-regulated 40.073
Rgs9regulator of G-protein signaling 90.072
Kcnj12potassium inwardly-rectifying channel, subfamily J, member 120.070
Olr1654olfactory receptor 16540.069
LOC100362824caveolin 2-like0.068
Erbb4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.066
Eef2eukaryotic translation elongation factor 20.064
Adora2aadenosine A2a receptor0.063
Nos3nitric oxide synthase 3, endothelial cell0.062
Map2microtubule-associated protein 20.062
Olr857olfactory receptor 8570.059
Prkcaprotein kinase C, alpha0.058
Sirpasignal-regulatory protein alpha0.058
Notch2Notch homolog 2 (Drosophila)0.058
CebpeCCAAT/enhancer binding protein (C/EBP), epsilon0.057
Sema6bsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B0.056
Pex5lperoxisomal biogenesis factor 5-like0.056
Htr1d5-hydroxytryptamine (serotonin) receptor 1D0.056
Gabrg3gamma-aminobutyric acid (GABA) A receptor, gamma 30.056
Ppp2r2cprotein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform0.056
Park2Parkinson disease (autosomal recessive, juvenile) 2, parkin0.055
Sc4molsterol-C4-methyl oxidase-like0.054
Abcc8ATP-binding cassette, subfamily C (CFTR/MRP), member 80.053
Dlg1discs, large homolog 1 (Drosophila)0.053
Matkmegakaryocyte-associated tyrosine kinase0.052
Atxn1ataxin 10.052
Kcnb1potassium voltage gated channel, Shab-related subfamily, member 10.050
Sqlesqualene epoxidase0.049
Cav2caveolin 20.049
Cacna1scalcium channel, voltage-dependent, L type, alpha 1S subunit0.049
Gria2glutamate receptor, ionotropic, AMPA 20.049
Serpina3nserine (or cysteine) peptidase inhibitor, clade A, member 3N0.048
Cishcytokine inducible SH2-containing protein0.048
Phkg1phosphorylase kinase, gamma 10.047
Strnstriatin, calmodulin binding protein0.047
Cav1caveolin 1, caveolae protein0.047
Tcf12transcription factor 120.047
Ccr5chemokine (C-C motif) receptor 50.046
Tcf4transcription factor 40.045
Cyp4a8cytochrome P450, family 4, subfamily a, polypeptide 80.045
Dlgap3discs, large (Drosophila) homolog-associated protein 30.044
Stxbp5syntaxin binding protein 5 (tomosyn)0.044
Slc1a6solute carrier family 1 (high affinity aspartate/glutamate transporter), member 60.044
Idi1isopentenyl-diphosphate delta isomerase 10.044
Hipk3homeodomain interacting protein kinase 30.043
Nrxn3neurexin 30.043
Klrb1akiller cell lectin-like receptor subfamily B, member 1A0.043
Eif4heukaryotic translation initiation factor 4H0.043
MosMoloney sarcoma oncogene0.043
Gng7guanine nucleotide binding protein (G protein), gamma 70.043
Kalrnkalirin, RhoGEF kinase0.043
Otx1orthodenticle homeobox 10.043
Mylk2myosin light chain kinase 20.042
Dio1deiodinase, iodothyronine, type I0.042
Itpr1inositol 1,4,5-triphosphate receptor, type 10.041
Vdrvitamin D (1,25- dihydroxyvitamin D3) receptor0.041
Ube3aubiquitin protein ligase E3A0.041
Hpcal4hippocalcin-like 40.041
Ntsr2neurotensin receptor 20.040
Akr1a1aldo-keto reductase family 1, member A1 (aldehyde reductase)0.040
Hmgcr3-hydroxy-3-methylglutaryl-Coenzyme A reductase0.040
Maneamannosidase, endo-alpha0.040
Acat3acetyl-Coenzyme A acetyltransferase 30.039
Robo1roundabout homolog 1 (Drosophila)0.039
RGD1564664similar to LOC387763 protein0.039
Lalbalactalbumin, alpha0.038
Maptmicrotubule-associated protein tau0.038
Pde4aphosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila)0.037
Kif1bkinesin family member 1B0.037
Begainbrain-enriched guanylate kinase-associated0.037
Reg3aregenerating islet-derived 3 alpha0.037
Exoc5exocyst complex component 50.037
Pak2p21 protein (Cdc42/Rac)-activated kinase 20.037
Nek9NIMA (never in mitosis gene a)- related kinase 90.036
Tcof1Treacher Collins-Franceschetti syndrome 1 homolog (human)0.036
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism