The network for 'negative regulation of vulval development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of vulval development

Any process that stops, prevents, or reduces the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.

NameDescriptionProbabilityFunc Analog Organism
egl-18Protein EGL-180.999
hcp-3Protein HCP-30.923
hlh-2Protein HLH-20.907
CELE_Y41E3.11Protein Y41E3.110.895
ldb-1Protein LDB-10.873
npp-4Protein NPP-40.857
snr-4Protein SNR-40.857
pry-1Protein PRY-10.857
eor-1Protein EOR-10.789
CELE_Y54G11A.11Protein Y54G11A.110.785
mep-1Protein MEP-10.784
egl-27Protein EGL-270.775
snr-2Protein SNR-20.764
mix-1Protein MIX-10.739
lin-36Protein LIN-360.738
eps-8Protein EPS-80.733
T09B4.2Protein T09B4.20.728
lig-1Protein LIG-10.712
T11G6.8Protein T11G6.80.705
emb-5Protein EMB-50.700
npp-1Protein NPP-10.689
sur-2Protein SUR-20.688
cdt-2Protein CDT-20.676
rpb-11Protein RPB-110.666
F08B4.7Protein F08B4.70.666
mab-5Protein MAB-50.651
hrpf-2Protein HRPF-20.649
dpy-22Protein DPY-220.648
unc-62Protein UNC-620.628
snr-6Protein SNR-60.625
npp-5Protein NPP-50.619
rbd-1Protein RBD-10.614
F35G12.4Protein F35G12.40.612
mes-3Protein MES-30.610
mcm-7Protein MCM-70.606
lin-25Protein LIN-250.600
athp-2Protein ATHP-20.598
pha-4Protein PHA-40.598
rpn-1Protein RPN-10.597
sas-4Protein SAS-40.583
cdk-8Protein CDK-80.583
mes-4Protein MES-40.581
lin-37Protein LIN-370.576
fkh-2Protein FKH-20.574
npp-7Protein NPP-70.574
set-2Protein SET-20.562
snr-1Protein SNR-10.556
rnr-1Protein RNR-10.556
CELE_C17H12.13Protein C17H12.130.550
swsn-2.1Protein SWSN-2.10.547
hlh-30Protein HLH-300.545
pde-4Protein PDE-40.543
dre-1Protein DRE-10.541
CELE_Y73F8A.25Protein Y73F8A.250.530
pole-2Protein POLE-20.526
egl-8Protein EGL-80.517
CELE_B0238.11Protein B0238.110.511
CELE_F19F10.9Protein F19F10.90.508
mog-4Protein MOG-40.505
pqn-65Protein PQN-650.504
lin-9Protein LIN-90.504
skp-1Protein SKP-10.499
fasn-1Protein FASN-10.496
vab-3Protein VAB-30.494
ZK930.1Protein ZK930.10.492
C02B10.4Protein C02B10.40.491
rpn-12Protein RPN-120.489
lst-3Protein LST-30.489
smc-3Protein SMC-30.487
pbs-7Protein PBS-70.483
ZC506.1Protein ZC506.10.477
lin-59Protein LIN-590.473
wnk-1Protein WNK-10.472
lin-53Protein LIN-530.470
hbl-1Protein HBL-10.469
lin-12Protein LIN-120.469
zen-4Protein ZEN-40.468
mdt-8Protein MDT-80.467
gpr-1Protein GPR-10.465
mig-5Protein MIG-50.464
gex-3Protein GEX-30.463
W04D2.6Protein W04D2.60.460
mat-3Protein MAT-30.459
B0511.12Protein B0511.120.457
smo-1Protein SMO-10.457
sma-6Protein SMA-60.456
wrm-1Protein WRM-10.447
pbrm-1Protein PBRM-10.447
gex-2Protein GEX-20.445
cdtl-7Protein CDTL-70.433
hda-1Protein HDA-10.432
CELE_C55A6.9Protein C55A6.90.425
sel-12Protein SEL-120.424
lin-35Protein LIN-350.424
rsp-1Protein RSP-10.422
vab-1Protein VAB-10.421
CELE_Y41D4B.11Protein Y41D4B.110.418
csn-1Protein CSN-10.417
rsp-5Protein RSP-50.413
snrp-200Protein SNRP-2000.409
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism