The network for 'heterochromatin assembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

heterochromatin assembly

The assembly of chromatin into heterochromatin, a compact and highly condensed form that is often, but not always, transcriptionally silent.

NameDescriptionProbabilityFunc Analog Organism
ZK1127.12Protein ZK1127.120.027
C34B2.3Protein C34B2.30.020
C05C12.5Protein C05C12.50.019
C18H7.7Protein C18H7.70.018
K11C4.1Protein K11C4.10.017
F10E9.4Protein F10E9.40.016
C15H11.8Protein C15H11.80.014
CELE_ZK550.5Protein ZK550.50.013
msp-49Protein MSP-490.013
B0495.9Protein B0495.90.013
F37A8.1Protein F37A8.10.012
mtx-2Protein MTX-20.012
T27F7.1Protein T27F7.10.012
CELE_C34D4.3Protein C34D4.30.011
C14C11.1Protein C14C11.10.011
CELE_Y51B9A.5Protein Y51B9A.50.011
F57F4.1Protein F57F4.10.010
CELE_F17E9.5Protein F17E9.50.010
F38H4.10Protein F38H4.100.010
msd-1Protein MSD-10.010
ZK930.4Protein ZK930.40.010
C09B9.2Protein C09B9.20.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Su(var)3-7Suppressor of variegation 3-70.207
Su(var)205Suppressor of variegation 2050.172
Jarid2CG3654 gene product from transcript CG3654-RD0.082
CTCFCG8591 gene product from transcript CG8591-RA0.077
pzgputzig0.070
pds5CG17509 gene product from transcript CG17509-RA0.059
BEAF-32Boundary element-associated factor of 32kD0.055
piwiCG6122 gene product from transcript CG6122-RA0.052
eggeggless0.036
JIL-1CG6297 gene product from transcript CG6297-RA0.034
E(var)3-9Enhancer of variegation 3-90.032
msl-3male-specific lethal 30.029
asf1anti-silencing factor 10.029
Suv4-20CG13363 gene product from transcript CG13363-RA0.028
mofmales absent on the first0.028
CG12256CG12256 gene product from transcript CG12256-RA0.021
Cap-H2Chromosome associated protein H20.017
Top2Topoisomerase 20.017
Mcm10Sensitized chromosome inheritance modifier 190.017
AGO2Argonaute 20.015
Chd1Chromodomain-helicase-DNA-binding protein 10.015
Bap55Brahma associated protein 55kD0.015
Mt2Methyltransferase 20.015
hdhumpty dumpty0.014
Mekk1CG7717 gene product from transcript CG7717-RB0.014
CG5180CG5180 gene product from transcript CG5180-RB0.014
Nf1Neurofibromin 10.014
msl-2male-specific lethal 20.013
Sry-betaSerendipity beta0.013
MBD-likeCG8208 gene product from transcript CG8208-RA0.013
trrtrithorax-related0.013
ClpClipper0.012
CG32418CG32418 gene product from transcript CG32418-RA0.011
Mi-2CG8103 gene product from transcript CG8103-RA0.011
His2AvHistone H2A variant0.011
CG11138CG11138 gene product from transcript CG11138-RC0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CBX5chromobox homolog 51.000
CBX1chromobox homolog 10.708
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.702
E2F3E2F transcription factor 30.424
ARID1AAT rich interactive domain 1A (SWI-like)0.375
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.289
ADNPactivity-dependent neuroprotector homeobox0.247
CARM1coactivator-associated arginine methyltransferase 10.243
HIST1H3Bhistone cluster 1, H3b0.137
LBRlamin B receptor0.130
CBX3chromobox homolog 30.127
TOP1topoisomerase (DNA) I0.107
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 20.098
BAZ1Bbromodomain adjacent to zinc finger domain, 1B0.093
RAD21RAD21 homolog (S. pombe)0.079
POGZpogo transposable element with ZNF domain0.079
SMARCA5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 50.075
SH3KBP1SH3-domain kinase binding protein 10.062
MBD1methyl-CpG binding domain protein 10.061
PBRM1polybromo 10.060
CHAF1Achromatin assembly factor 1, subunit A (p150)0.054
PRRC2Cproline-rich coiled-coil 2C0.046
CYFIP2cytoplasmic FMR1 interacting protein 20.043
SUZ12suppressor of zeste 12 homolog (Drosophila)0.042
INCENPinner centromere protein antigens 135/155kDa0.042
LRIF1ligand dependent nuclear receptor interacting factor 10.037
CHD4chromodomain helicase DNA binding protein 40.035
PRKDCprotein kinase, DNA-activated, catalytic polypeptide0.033
PRMT6protein arginine methyltransferase 60.033
SMARCB1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 10.029
PHIPpleckstrin homology domain interacting protein0.028
HDAC2histone deacetylase 20.024
AP1M1adaptor-related protein complex 1, mu 1 subunit0.024
ARID2AT rich interactive domain 2 (ARID, RFX-like)0.022
ARID1BAT rich interactive domain 1B (SWI1-like)0.021
HNRNPUheterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)0.021
SMC3structural maintenance of chromosomes 30.016
NIPBLNipped-B homolog (Drosophila)0.016
LDOC1leucine zipper, down-regulated in cancer 10.016
DNMT1DNA (cytosine-5-)-methyltransferase 10.015
CHAF1Bchromatin assembly factor 1, subunit B (p60)0.014
ZNF638zinc finger protein 6380.014
RB1retinoblastoma 10.013
CYFIP1cytoplasmic FMR1 interacting protein 10.013
FAM46Afamily with sequence similarity 46, member A0.012
TPRtranslocated promoter region (to activated MET oncogene)0.012
RBBP4retinoblastoma binding protein 40.012
SRP9signal recognition particle 9kDa0.011
NSL1NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)0.011
RIF1RAP1 interacting factor homolog (yeast)0.010
NUP98nucleoporin 98kDa0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Smarca5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 50.876
Trim24tripartite motif-containing 240.832
Smarcc1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.559
Smc2structural maintenance of chromosomes 20.472
Fmr1fragile X mental retardation syndrome 1 homolog0.393
Nucks1nuclear casein kinase and cyclin-dependent kinase substrate 10.364
Chaf1achromatin assembly factor 1, subunit A (p150)0.284
Baz1bbromodomain adjacent to zinc finger domain, 1B0.157
Cenpc1centromere protein C10.150
C330027C09RikRIKEN cDNA C330027C09 gene0.096
Sfpqsplicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)0.094
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.075
Arid1aAT rich interactive domain 1A (SWI-like)0.071
Fxr1fragile X mental retardation gene 1, autosomal homolog0.064
Kdm2blysine (K)-specific demethylase 2B0.061
Hmgb1high mobility group box 10.056
Casp8ap2caspase 8 associated protein 20.046
Srsf1serine/arginine-rich splicing factor 10.039
Myef2myelin basic protein expression factor 2, repressor0.038
Chd4chromodomain helicase DNA binding protein 40.037
Surf4surfeit gene 40.037
Trim28tripartite motif-containing 280.037
Taf3TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor0.035
Hist1h3ghistone cluster 1, H3g0.032
Cbx1chromobox homolog 1 (Drosophila HP1 beta)0.032
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.031
Pld3phospholipase D family, member 30.030
Anp32eacidic (leucine-rich) nuclear phosphoprotein 32 family, member E0.029
Pola1polymerase (DNA directed), alpha 10.028
Huwe1HECT, UBA and WWE domain containing 10.027
Acbd3acyl-Coenzyme A binding domain containing 30.027
Hnrnpdheterogeneous nuclear ribonucleoprotein D0.027
Smc1astructural maintenance of chromosomes 1A0.027
Rcan1regulator of calcineurin 10.026
Hnrnpuheterogeneous nuclear ribonucleoprotein U0.025
Trp53transformation related protein 530.024
Arid1bAT rich interactive domain 1B (SWI-like)0.023
Smc3structural maintenace of chromosomes 30.022
Syncripsynaptotagmin binding, cytoplasmic RNA interacting protein0.022
Ckbcreatine kinase, brain0.022
Hnrnpa2b1heterogeneous nuclear ribonucleoprotein A2/B10.022
Eif4g1eukaryotic translation initiation factor 4, gamma 10.022
Atrxalpha thalassemia/mental retardation syndrome X-linked homolog (human)0.021
Ube2oubiquitin-conjugating enzyme E2O0.020
Hnrnph1heterogeneous nuclear ribonucleoprotein H10.020
Tmpothymopoietin0.020
Cbx3chromobox homolog 3 (Drosophila HP1 gamma)0.019
Rif1Rap1 interacting factor 1 homolog (yeast)0.019
Sgtasmall glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha0.018
Dtldenticleless homolog (Drosophila)0.018
Eri2exoribonuclease 20.018
Tprtranslocated promoter region0.018
Ccar1cell division cycle and apoptosis regulator 10.018
Ncapg2non-SMC condensin II complex, subunit G20.018
Pabpn1poly(A) binding protein, nuclear 10.017
Aspmasp (abnormal spindle)-like, microcephaly associated (Drosophila)0.017
Ppigpeptidyl-prolyl isomerase G (cyclophilin G)0.016
Agap3ArfGAP with GTPase domain, ankyrin repeat and PH domain 30.016
L3mbtl2l(3)mbt-like 2 (Drosophila)0.016
Nclnucleolin0.016
Dkc1dyskeratosis congenita 1, dyskerin homolog (human)0.016
Cnot6CCR4-NOT transcription complex, subunit 60.016
Creb1cAMP responsive element binding protein 10.016
Larp7La ribonucleoprotein domain family, member 70.015
SetSET nuclear oncogene0.015
Khdrbs1KH domain containing, RNA binding, signal transduction associated 10.015
Eif4eeukaryotic translation initiation factor 4E0.015
Hnrnpa1heterogeneous nuclear ribonucleoprotein A10.015
Cstf2cleavage stimulation factor, 3' pre-RNA subunit 20.015
Lin9lin-9 homolog (C. elegans)0.014
Mdm4transformed mouse 3T3 cell double minute 40.014
Cbx5chromobox homolog 5 (Drosophila HP1a)0.014
Terf1telomeric repeat binding factor 10.014
Tnrc6btrinucleotide repeat containing 6b0.014
Tnpo2transportin 2 (importin 3, karyopherin beta 2b)0.014
Supt16hsuppressor of Ty 16 homolog (S. cerevisiae)0.014
Pnnpinin0.014
Atad2ATPase family, AAA domain containing 20.014
Mecp2methyl CpG binding protein 20.013
Haus6HAUS augmin-like complex, subunit 60.013
Hnrnpul2heterogeneous nuclear ribonucleoprotein U-like 20.013
Hcfc1host cell factor C10.013
Obfc2boligonucleotide/oligosaccharide-binding fold containing 2B0.013
Hdac5histone deacetylase 50.013
Tnpo1transportin 10.012
Cbx7chromobox homolog 70.012
Fam53afamily with sequence similarity 53, member A0.012
Nup155nucleoporin 1550.012
Atp9aATPase, class II, type 9A0.012
Srsf7serine/arginine-rich splicing factor 70.012
Ylpm1YLP motif containing 10.012
Nacc1nucleus accumbens associated 1, BEN and BTB (POZ) domain containing0.012
Chek1checkpoint kinase 1 homolog (S. pombe)0.012
Suz12suppressor of zeste 12 homolog (Drosophila)0.012
Scaf4SR-related CTD-associated factor 40.012
Topbp1topoisomerase (DNA) II binding protein 10.012
Pogzpogo transposable element with ZNF domain0.012
Hist1h1ehistone cluster 1, H1e0.012
Cdc7cell division cycle 7 (S. cerevisiae)0.012
Ewsr1Ewing sarcoma breakpoint region 10.012
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism