The network for 'axon extension' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

axon extension

Long distance growth of a single axon process involved in cellular development.

NameDescriptionProbabilityFunc Analog Organism
ten-1Protein TEN-10.885
unc-9Protein UNC-90.720
egl-18Protein EGL-180.638
vab-3Protein VAB-30.554
egl-46Protein EGL-460.481
hlh-1Protein HLH-10.401
nhr-67Protein NHR-670.374
flt-1Protein FLT-10.360
pha-4Protein PHA-40.333
cnd-1Protein CND-10.331
unc-6Protein UNC-60.304
fmi-1Protein FMI-10.293
ina-1Protein INA-10.286
ceh-20Protein CEH-200.285
cam-1Protein CAM-10.274
lin-12Protein LIN-120.259
F28E10.1Protein F28E10.10.194
lin-11Protein LIN-110.189
che-1Protein CHE-10.188
hlh-2Protein HLH-20.187
lin-29Protein LIN-290.183
W03G9.3Protein W03G9.30.163
unc-73Protein UNC-730.159
Y82E9BR.13Protein Y82E9BR.130.154
sax-3Protein SAX-30.137
CELE_C38D4.1Protein C38D4.10.137
pry-1Protein PRY-10.133
elt-6Protein ELT-60.128
mig-2Protein MIG-20.125
hbl-1Protein HBL-10.124
let-60Protein LET-600.121
C11E4.6Protein C11E4.60.110
somi-1Protein SOMI-10.106
hnd-1Protein HND-10.105
osm-3Protein OSM-30.095
tbb-4Protein TBB-40.093
unc-40Protein UNC-400.091
igcm-3Protein IGCM-30.091
lsy-2Protein LSY-20.090
pkg-1Protein PKG-10.088
lrp-2Protein LRP-20.087
ceh-13Protein CEH-130.086
syg-2Protein SYG-20.085
F54E4.3Protein F54E4.30.081
ceh-48Protein CEH-480.075
odr-3Protein ODR-30.073
R10E12.2Protein R10E12.20.073
atat-2Protein ATAT-20.073
cwn-1Protein CWN-10.072
ttx-1Protein TTX-10.072
ida-1Protein IDA-10.069
ldb-1Protein LDB-10.069
nphp-4Protein NPHP-40.067
ahr-1Protein AHR-10.066
trim-9Protein TRIM-90.065
che-3Protein CHE-30.065
hlh-14Protein HLH-140.064
mab-5Protein MAB-50.064
rig-6Protein RIG-60.064
zig-10Protein ZIG-100.063
inx-19Protein INX-190.059
atgp-2Protein ATGP-20.059
gei-18Protein GEI-180.058
jac-1Protein JAC-10.057
spc-1Protein SPC-10.055
ncam-1Protein NCAM-10.055
gcy-22Protein GCY-220.055
pkc-1Protein PKC-10.054
sli-1Protein SLI-10.052
pat-3Protein PAT-30.051
pgl-3Protein PGL-30.049
egl-8Protein EGL-80.049
madf-2Protein MADF-20.048
smp-1Protein SMP-10.047
egl-23Protein EGL-230.047
unc-104Protein UNC-1040.047
goa-1Protein GOA-10.046
avr-14Protein AVR-140.046
kvs-2Protein KVS-20.045
unc-47Protein UNC-470.044
daf-3Protein DAF-30.044
enu-3Protein ENU-30.041
arl-3Protein ARL-30.041
ncl-1Protein NCL-10.040
F58H1.5Protein F58H1.50.040
ceh-16Protein CEH-160.040
syg-1Protein SYG-10.039
ceh-36Protein CEH-360.039
ceh-27Protein CEH-270.039
eva-1Protein EVA-10.039
pdfr-1Protein PDFR-10.039
rga-2Protein RGA-20.039
unc-5Protein UNC-50.038
atg-2Protein ATG-20.037
sfrp-1Protein SFRP-10.037
cdh-3Protein CDH-30.037
sdz-28Protein SDZ-280.036
syd-9Protein SYD-90.036
C43H6.6Protein C43H6.60.036
unc-38Protein UNC-380.035
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
lhx2bLIM homeobox 2b0.988
ascl1aachaete-scute complex-like 1a (Drosophila)0.974
foxd3forkhead box D30.948
foxa1forkhead box A10.921
phox2apaired-like homeobox 2a0.832
bocbrother of CDO0.806
robo1roundabout homolog 10.748
itgb1b.2integrin, beta 1b.20.742
hgfahepatocyte growth factor a0.729
neo1neogenin 10.698
wnt3wingless-type MMTV integration site family, member 30.667
shhasonic hedgehog a0.653
nrp1aneuropilin 1a0.653
phox2bpaired-like homeobox 2b0.647
dbx1adeveloping brain homeobox 1a0.646
tbx1T-box 10.625
barhl2BarH-like 20.615
sulf1sulfatase 10.592
stac3SH3 and cysteine rich domain 30.574
robo3roundabout homolog 30.516
robo2roundabout homolog 20.513
dag1dystroglycan 10.496
lef1lymphocyte enhancer binding factor 10.475
pafah1b1aplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a0.473
wnt9bwingless-type MMTV integration site family, member 9B0.472
fgfr1afibroblast growth factor receptor 1a0.468
efnb1ephrin B10.461
nxph1neurexophilin 10.461
cdh23cadherin-like 230.438
thtyrosine hydroxylase0.404
wnt8bwingless-type MMTV integration site family, member 8b0.395
evx1even-skipped homeobox 10.395
metmet proto-oncogene (hepatocyte growth factor receptor)0.381
olfm2olfactomedin 20.378
bmp2abone morphogenetic protein 2a0.377
foxp2forkhead box P20.373
hey1hairy/enhancer-of-split related with YRPW motif 10.350
emx3empty spiracles homeobox 30.349
neurog1neurogenin 10.345
grnagranulin a0.329
gli1GLI-Kruppel family member 10.314
gata2aGATA-binding protein 2a0.304
sdc2syndecan 20.300
tal2T-cell acute lymphocytic leukemia 20.283
extl3exostoses (multiple)-like 30.278
lhx6LIM homeobox 60.278
epb4.1l4erythrocyte protein band 4.1-like 40.267
disp1dispatched homolog 1 (Drosophila)0.265
efnb2aephrin B2a0.263
lama2laminin, alpha 20.262
crhcorticotropin releasing hormone0.262
olig2oligodendrocyte lineage transcription factor 20.257
ptpraprotein tyrosine phosphatase, receptor type, A0.257
fezf2FEZ family zinc finger 20.255
sim1asingle-minded homolog 1a (Drosophila)0.252
prdm14PR domain containing 140.239
nr2f1bnuclear receptor subfamily 2, group F, member 1b0.236
hhiphedgehog interacting protein0.232
ephb4beph receptor B4b0.227
ebf3early B-cell factor 30.226
sema3absemaphorin 3ab0.226
ret1receptor tyrosine kinase0.224
gli2aGLI-Kruppel family member GLI2a0.223
nrp2bneuropilin 2b0.221
nadl1.2neural adhesion molecule L1.20.220
nrp1bneuropilin 1b0.218
igfbp3insulin-like growth factor binding protein 30.212
otx5orthodenticle homolog 50.207
zbtb4zinc finger and BTB domain containing 40.198
dlx2adistal-less homeobox gene 2a0.197
sfrp1asecreted frizzled-related protein 1a0.196
atp2a1ATPase, Ca++ transporting, cardiac muscle, fast twitch 10.196
cdh6cadherin 60.193
wnt1wingless-type MMTV integration site family, member 10.192
jag2jagged 20.192
flhfloating head0.192
elavl3ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)0.190
col2a1acollagen type II, alpha-1a0.185
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.179
pax2apaired box gene 2a0.179
ptch2patched 20.178
gfra1agdnf family receptor alpha 1a0.174
tac1tachykinin 10.173
insm1ainsulinoma-associated 1a0.171
pdlim4PDZ and LIM domain 40.168
wnt4awingless-type MMTV integration site family, member 4a0.168
unc45aunc-45 homolog A (C. elegans)0.167
kal1aKallmann syndrome 1a sequence0.167
cntn2contactin 20.156
wnt10awingless-type MMTV integration site family, member 10a0.155
tpbgltrophoblast glycoprotein-like0.155
fzd7afrizzled homolog 7a0.154
her15.1hairy and enhancer of split-related 15.10.150
otpaorthopedia homolog a0.150
fgfr1bfibroblast growth factor receptor 1b0.148
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Rac1CG2248 gene product from transcript CG2248-RA0.986
trioCG18214 gene product from transcript CG18214-RA0.820
Fas2Fasciclin 20.755
stanstarry night0.729
DscamDown syndrome cell adhesion molecule0.648
Pi3K92ECG4141 gene product from transcript CG4141-RB0.645
futschCG34387 gene product from transcript CG34387-RC0.618
fz2frizzled 20.610
Sema-2aCG4700 gene product from transcript CG4700-RC0.603
Wnt2Wnt oncogene analog 20.596
drkdownstream of receptor kinase0.568
Rab5Rab-protein 50.483
Rho1CG8416 gene product from transcript CG8416-RB0.480
CG33960CG33960 gene product from transcript CG33960-RB0.473
Sema-1aCG18405 gene product from transcript CG18405-RD0.470
Ptp69DProtein tyrosine phosphatase 69D0.464
AblAbl tyrosine kinase0.440
Fmr1CG6203 gene product from transcript CG6203-RC0.434
jebjelly belly0.416
unc-5CG8166 gene product from transcript CG8166-RA0.404
Liprin-alphaCG11199 gene product from transcript CG11199-RB0.402
gekgenghis khan0.379
crolcrooked legs0.359
plexBplexin B0.320
unc-104CG8566 gene product from transcript CG8566-RB0.318
gogogolden goal0.312
Drl-2Derailed 20.303
jingCG9397 gene product from transcript CG9397-RI0.292
EphrinCG1862 gene product from transcript CG1862-RA0.291
Fak56DFocal Adhesion Kinase0.289
Akt1CG4006 gene product from transcript CG4006-RA0.282
Wnt5Wnt oncogene analog 50.272
MadMothers against dpp0.245
HLHm7E(spl) region transcript m70.196
nwknervous wreck0.191
Aplip1APP-like protein interacting protein 10.189
Sra-1specifically Rac1-associated protein 10.185
witwishful thinking0.175
katanin-60katanin 600.173
wbwing blister0.168
CaMKIICalcium/calmodulin-dependent protein kinase II0.157
Gyc76CGuanylyl cyclase at 76C0.156
Hr51Hormone receptor 510.156
par-1CG8201 gene product from transcript CG8201-RA0.156
rtGEFrho-type guanine exchange factor0.153
endoAendophilin A0.134
PP2A-B'CG7913 gene product from transcript CG7913-RK0.128
robo3CG5423 gene product from transcript CG5423-RA0.114
Nrx-IVNeurexin IV0.112
botvbrother of tout-velu0.111
CG8064CG8064 gene product from transcript CG8064-RA0.109
cdicenter divider0.105
Arp66BActin-related protein 66B0.105
Trim9CG31721 gene product from transcript CG31721-RB0.103
RhoGAPp190CG32555 gene product from transcript CG32555-RB0.102
lunaCG33473 gene product from transcript CG33473-RB0.099
HLHmgammaE(spl) region transcript mgamma0.099
neuroliginCG13772 gene product from transcript CG13772-RA0.097
malphaE(spl) region transcript malpha0.096
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
FLNAfilamin A, alpha0.831
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.769
APCadenomatous polyposis coli0.769
FGF1fibroblast growth factor 1 (acidic)0.708
FGFR1fibroblast growth factor receptor 10.692
MAP2K4mitogen-activated protein kinase kinase 40.616
FMR1fragile X mental retardation 10.556
DVL3dishevelled, dsh homolog 3 (Drosophila)0.539
ACTN2actinin, alpha 20.367
FGFR2fibroblast growth factor receptor 20.363
MPRIPmyosin phosphatase Rho interacting protein0.348
DHX30DEAH (Asp-Glu-Ala-His) box polypeptide 300.328
DLG4discs, large homolog 4 (Drosophila)0.294
ATG13ATG13 autophagy related 13 homolog (S. cerevisiae)0.281
MAP3K1mitogen-activated protein kinase kinase kinase 10.275
MAPK8mitogen-activated protein kinase 80.240
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)0.225
ATN1atrophin 10.224
HSPG2heparan sulfate proteoglycan 20.220
TRIOtriple functional domain (PTPRF interacting)0.213
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.195
CLASP1cytoplasmic linker associated protein 10.159
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.157
LRP6low density lipoprotein receptor-related protein 60.157
NCKAP1NCK-associated protein 10.151
MAP1LC3Bmicrotubule-associated protein 1 light chain 3 beta0.146
GSK3Bglycogen synthase kinase 3 beta0.133
LRRK2leucine-rich repeat kinase 20.123
NAV1neuron navigator 10.119
DISC1disrupted in schizophrenia 10.102
ATF2activating transcription factor 20.100
DVL1dishevelled, dsh homolog 1 (Drosophila)0.098
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.092
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.087
SEMA6Dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D0.079
ATXN1ataxin 10.075
CBX8chromobox homolog 80.071
ITGB4integrin, beta 40.070
ADAM19ADAM metallopeptidase domain 190.068
ZNF512Bzinc finger protein 512B0.067
HNRNPUheterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)0.064
MAPK8IP1mitogen-activated protein kinase 8 interacting protein 10.063
KIF5Bkinesin family member 5B0.062
ARRB1arrestin, beta 10.059
MAP1Bmicrotubule-associated protein 1B0.059
CSNK1Ecasein kinase 1, epsilon0.058
PLXND1plexin D10.058
RNF2ring finger protein 20.057
USP11ubiquitin specific peptidase 110.056
SCHIP1schwannomin interacting protein 10.055
MAPK8IP3mitogen-activated protein kinase 8 interacting protein 30.053
CYFIP1cytoplasmic FMR1 interacting protein 10.053
RANBP2RAN binding protein 20.050
DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked0.049
SORBS1sorbin and SH3 domain containing 10.048
CBX6chromobox homolog 60.045
MAPTmicrotubule-associated protein tau0.045
PTCH1patched 10.044
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.043
TRIP6thyroid hormone receptor interactor 60.042
FN1fibronectin 10.041
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.040
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.040
GAS7growth arrest-specific 70.039
DHX9DEAH (Asp-Glu-Ala-His) box polypeptide 90.039
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A0.039
G3BP1GTPase activating protein (SH3 domain) binding protein 10.038
JUNjun proto-oncogene0.037
MKL1megakaryoblastic leukemia (translocation) 10.037
ERBB2IPerbb2 interacting protein0.036
NTRK1neurotrophic tyrosine kinase, receptor, type 10.036
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.034
MAP3K5mitogen-activated protein kinase kinase kinase 50.033
JUPjunction plakoglobin0.033
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.032
NDEL1nudE nuclear distribution gene E homolog (A. nidulans)-like 10.032
FGF10fibroblast growth factor 100.030
RASA1RAS p21 protein activator (GTPase activating protein) 10.030
CD74CD74 molecule, major histocompatibility complex, class II invariant chain0.029
FBXO7F-box protein 70.029
ITGA3integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)0.029
HNRNPKheterogeneous nuclear ribonucleoprotein K0.027
FZD1frizzled homolog 1 (Drosophila)0.027
FGF2fibroblast growth factor 2 (basic)0.027
EGFRepidermal growth factor receptor0.027
RHOAras homolog gene family, member A0.027
CNOT6CCR4-NOT transcription complex, subunit 60.026
RING1ring finger protein 10.025
MYOD1myogenic differentiation 10.025
SPAG9sperm associated antigen 90.025
MACF1microtubule-actin crosslinking factor 10.024
CAPRIN1cell cycle associated protein 10.024
PLCG1phospholipase C, gamma 10.023
ABI2abl-interactor 20.023
NTRK3neurotrophic tyrosine kinase, receptor, type 30.023
GABARAPGABA(A) receptor-associated protein0.022
NTRK2neurotrophic tyrosine kinase, receptor, type 20.022
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Gria1glutamate receptor, ionotropic, AMPA 10.086
Nrxn1neurexin 10.085
Cacnb1calcium channel, voltage-dependent, beta 1 subunit0.083
Nek9NIMA (never in mitosis gene a)- related kinase 90.073
Dlgap3discs, large (Drosophila) homolog-associated protein 30.065
Tcf4transcription factor 40.062
Robo1roundabout homolog 1 (Drosophila)0.053
Gria2glutamate receptor, ionotropic, AMPA 20.052
Robo2roundabout homolog 2 (Drosophila)0.052
Nfibnuclear factor I/B0.049
Nfixnuclear factor I/X (CCAAT-binding transcription factor)0.048
Ppap2bphosphatidic acid phosphatase type 2B0.047
Dlgap1discs, large (Drosophila) homolog-associated protein 10.040
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.040
Ncam1neural cell adhesion molecule 10.037
Begainbrain-enriched guanylate kinase-associated0.036
Dlg4discs, large homolog 4 (Drosophila)0.034
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.033
Tmod2tropomodulin 20.031
Map2microtubule-associated protein 20.031
Slc6a11solute carrier family 6 (neurotransmitter transporter, GABA), member 110.031
Grm3glutamate receptor, metabotropic 30.030
Tcof1Treacher Collins-Franceschetti syndrome 1 homolog (human)0.029
Ctnnd2catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)0.029
Syt4synaptotagmin IV0.028
Lamc1laminin, gamma 10.027
Camk2gcalcium/calmodulin-dependent protein kinase II gamma0.026
Gabrb3gamma-aminobutyric acid (GABA) A receptor, beta 30.026
Elavl4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)0.026
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.026
Rhoaras homolog gene family, member A0.025
Grip1glutamate receptor interacting protein 10.025
Unc5bunc-5 homolog B (C. elegans)0.025
Sv2asynaptic vesicle glycoprotein 2a0.025
Rap1bRAP1B, member of RAS oncogene family0.025
Ednrbendothelin receptor type B0.024
Magi2membrane associated guanylate kinase, WW and PDZ domain containing 20.023
Camk2acalcium/calmodulin-dependent protein kinase II alpha0.023
Adcy5adenylate cyclase 50.022
Map1amicrotubule-associated protein 1A0.022
P4hbprolyl 4-hydroxylase, beta polypeptide0.021
Nfianuclear factor I/A0.021
Mll5myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)0.020
Caskin1CASK interacting protein 10.020
Erbb4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.020
Klc1kinesin light chain 10.020
Sema6bsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B0.020
Nos2nitric oxide synthase 2, inducible0.020
Gdf11growth differentiation factor 110.020
Cugbp2CUG triplet repeat, RNA binding protein 20.019
Shank1SH3 and multiple ankyrin repeat domains 10.019
Atp1b2ATPase, Na+/K+ transporting, beta 2 polypeptide0.019
Slc28a1solute carrier family 28 (sodium-coupled nucleoside transporter), member 10.019
Klf13Kruppel-like factor 130.019
Galntl1UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 10.019
Lrp1low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)0.019
LOC100359454hypothetical protein LOC1003594540.019
Znf76zinc finger protein 76 (expressed in testis)0.019
Cacna1scalcium channel, voltage-dependent, L type, alpha 1S subunit0.018
Arpc5actin related protein 2/3 complex, subunit 50.018
Timp2TIMP metallopeptidase inhibitor 20.018
Neurod2neurogenic differentiation 20.018
Akap5A kinase (PRKA) anchor protein 50.018
Sstr1somatostatin receptor 10.018
Syn1synapsin I0.017
Syt3synaptotagmin III0.017
Gnalguanine nucleotide binding protein, alpha stimulating, olfactory type0.017
Grin1glutamate receptor, ionotropic, N-methyl D-aspartate 10.017
Camk4calcium/calmodulin-dependent protein kinase IV0.017
Ehfets homologous factor0.016
Kcnb1potassium voltage gated channel, Shab-related subfamily, member 10.016
Trhrthyrotropin releasing hormone receptor0.016
Faim2Fas apoptotic inhibitory molecule 20.016
Sparcsecreted protein, acidic, cysteine-rich (osteonectin)0.016
Kcnj11potassium inwardly rectifying channel, subfamily J, member 110.016
Klc2kinesin light chain 20.016
Cacna1acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.016
Abcc1ATP-binding cassette, subfamily C (CFTR/MRP), member 10.016
Prkceprotein kinase C, epsilon0.015
Anxa2annexin A20.015
Gnb4guanine nucleotide binding protein (G protein), beta polypeptide 40.015
Sdc3syndecan 30.015
Atrxalpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)0.015
Apba1amyloid beta (A4) precursor protein-binding, family A, member 10.015
Map1bmicrotubule-associated protein 1B0.015
Ccnd2cyclin D20.015
Mrasmuscle RAS oncogene homolog0.015
Kalrnkalirin, RhoGEF kinase0.015
Pdlim5PDZ and LIM domain 50.015
Nedd4neural precursor cell expressed, developmentally down-regulated 40.014
Pxdnperoxidasin homolog (Drosophila)0.014
Maptmicrotubule-associated protein tau0.014
Igf1insulin-like growth factor 10.014
Lhx1LIM homeobox 10.014
Gabra4gamma-aminobutyric acid (GABA) A receptor, alpha 40.014
Dchs1dachsous 1 (Drosophila)0.014
MosMoloney sarcoma oncogene0.014
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism