The network for 'nucleobase containing compound catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

nucleobase containing compound catabolic process

The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids.

NameDescriptionProbabilityFunc Analog Organism
goa-1Protein GOA-10.694
let-60Protein LET-600.407
etr-1Protein ETR-10.357
fln-2Protein FLN-20.349
D2085.4Protein D2085.40.349
abts-1Protein ABTS-10.293
D1081.8Protein D1081.80.287
alx-1Protein ALX-10.281
glh-4Protein GLH-40.279
gpb-1Protein GPB-10.240
mtm-9Protein MTM-90.240
mei-1Protein MEI-10.238
sem-5Protein SEM-50.235
pgl-1Protein PGL-10.230
gpr-2Protein GPR-20.225
mcm-5Protein MCM-50.223
nhr-46Protein NHR-460.222
prpf-4Protein PRPF-40.218
rsd-2Protein RSD-20.217
F56D2.6Protein F56D2.60.215
CELE_F47G4.4Protein F47G4.40.213
cyc-1Protein CYC-10.213
gei-18Protein GEI-180.212
gpr-1Protein GPR-10.211
unc-54Protein UNC-540.211
klp-15Protein KLP-150.210
sax-3Protein SAX-30.209
lfi-1Protein LFI-10.199
tag-170Protein TAG-1700.199
ced-10Protein CED-100.195
rars-2Protein RARS-20.190
F33E11.3Protein F33E11.30.181
pkg-1Protein PKG-10.181
Y87G2A.1Protein Y87G2A.10.180
rhgf-2Protein RHGF-20.173
lin-5Protein LIN-50.173
mcm-2Protein MCM-20.168
miro-1Protein MIRO-10.165
nst-1Protein NST-10.164
ttx-1Protein TTX-10.162
ntl-2Protein NTL-20.158
C37H5.5Protein C37H5.50.157
CELE_W03F9.10Protein W03F9.100.156
sup-17Protein SUP-170.153
Y44E3A.6Protein Y44E3A.60.153
jnk-1Protein JNK-10.149
CELE_F29C4.2Protein F29C4.20.144
F54E12.2Protein F54E12.20.139
byn-1Protein BYN-10.138
ykt-6Protein YKT-60.137
tbc-2Protein TBC-20.137
sas-6Protein SAS-60.137
rnr-1Protein RNR-10.136
hsp-16.1Protein HSP-16.10.136
CELE_Y48B6A.1Protein Y48B6A.10.136
R06C1.4Protein R06C1.40.135
C49H3.6Protein C49H3.60.135
F26B1.2Protein F26B1.20.132
rpt-4Protein RPT-40.132
CELE_F17C11.10Protein F17C11.100.131
rfc-1Protein RFC-10.130
cls-2Protein CLS-20.127
R10H10.7Protein R10H10.70.126
chc-1Protein CHC-10.126
tag-315Protein TAG-3150.125
nap-1Protein NAP-10.122
Y73E7A.2Protein Y73E7A.20.121
K10C9.3Protein K10C9.30.121
F55C12.5Protein F55C12.50.121
T23F2.2Protein T23F2.20.121
apb-1Protein APB-10.121
unc-71Protein UNC-710.119
R53.4Protein R53.40.117
thoc-2Protein THOC-20.117
aspm-1Protein ASPM-10.117
lin-45Protein LIN-450.116
npp-20Protein NPP-200.116
tba-2Protein TBA-20.115
R148.3Protein R148.30.115
rpn-9Protein RPN-90.115
bet-2Protein BET-20.115
CELE_F32A7.5Protein F32A7.50.115
cdc-7Protein CDC-70.114
rnp-7Protein RNP-70.113
gro-1Protein GRO-10.113
T23F11.1Protein T23F11.10.111
atx-3Protein ATX-30.110
CELE_F08D12.1Protein F08D12.10.109
F41C3.4Protein F41C3.40.109
swsn-4Protein SWSN-40.108
pptr-2Protein PPTR-20.107
CELE_W09C5.8Protein W09C5.80.106
pqn-85Protein PQN-850.106
CELE_W09C5.1Protein W09C5.10.105
eng-1Protein ENG-10.104
ret-1Protein RET-10.104
dpy-21Protein DPY-210.104
unc-40Protein UNC-400.103
C23H3.5Protein C23H3.50.103
mig-15Protein MIG-150.103
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
ef1aelongation factor 1-alpha0.192
atp1b1bATPase, Na+/K+ transporting, beta 1b polypeptide0.135
sumo3aSMT3 suppressor of mif two 3 homolog 3a0.068
LOC570775protein argonaute-1-like0.060
cacnb1calcium channel, voltage-dependent, beta 1 subunit0.058
eomesaeomesodermin homolog a0.058
pak2ap21 (CDKN1A)-activated kinase 2a0.051
bidaBH3 interacting domain death agonist0.051
fanclFanconi anemia, complementation group L0.046
bactin2bactin20.046
plxnb2aplexin b2a0.042
arpc5aactin related protein 2/3 complex, subunit 5A0.042
gna13bguanine nucleotide binding protein (G protein), alpha 13b0.041
ryr3ryanodine receptor 30.037
adcyap1badenylate cyclase activating polypeptide 1b0.036
msh2mutS homolog 2 (E. coli)0.035
hspa4aheat shock protein 4a0.034
ndufs4NADH dehydrogenase (ubiquinone) Fe-S protein 4, (NADH-coenzyme Q reductase)0.033
mcm6MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae)0.033
aaasachalasia, adrenocortical insufficiency, alacrimia0.032
sass6spindle assembly 6 homolog (C. elegans)0.032
gna14guanine nucleotide binding protein (G protein), alpha 140.032
nf1aneurofibromin 1a0.031
tnni2a.4troponin I, skeletal, fast 2a.40.029
tm9sf4transmembrane 9 superfamily protein member 40.029
eif2c4eukaryotic translation initiation factor 2C, 40.028
snx6sorting nexin 60.028
tgfb3transforming growth factor, beta 30.028
atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.027
smg5Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)0.027
sdad1SDA1 domain containing 10.026
myhz1.2myosin, heavy polypeptide 1.2, skeletal muscle0.026
atp1a1a.4ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide0.026
prim1primase polypeptide 10.025
zgc:65894zgc:658940.025
hsp90a.2heat shock protein 90-alpha 20.025
yes1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 10.024
cdc42ep1CDC42 effector protein (Rho GTPase binding) 10.024
ppargperoxisome proliferator activated receptor gamma0.024
cct7chaperonin containing TCP1, subunit 7 (eta)0.024
srmspermidine synthase0.023
stau2staufen, RNA binding protein, homolog 2 (Drosophila)0.023
nme2b.2non-metastatic cells 2b.2, protein (NM23B) expressed in0.023
bactin1bactin10.023
dlatdihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)0.023
arf5ADP-ribosylation factor 50.022
tmem93transmembrane protein 930.022
tnnt3btroponin T3b, skeletal, fast0.022
srprsignal recognition particle receptor (docking protein)0.021
s100v2S100 calcium binding protein V20.021
pvalb4parvalbumin 40.021
acheacetylcholinesterase0.021
eif4eeukaryotic translation initiation factor 4e0.021
unguracil-DNA glycosylase0.020
paxip1PAX interacting (with transcription-activation domain) protein 10.019
znf711zinc finger protein 7110.019
zgc:77052zgc:770520.019
LOC100003514protein kinase C alpha type-like0.019
dag1dystroglycan 10.019
h2afvlH2A histone family, member V, like0.019
rbmxRNA binding motif protein, X-linked0.019
ddx42DEAD (Asp-Glu-Ala-Asp) box polypeptide 420.019
h3f3cH3 histone, family 3C0.019
ilkintegrin linked kinase0.019
znf259zinc finger protein 2590.019
cand1cullin-associated and neddylation-dissociated 10.018
eif3s10eukaryotic translation initiation factor 3, subunit 10 (theta)0.018
disc1disrupted in schizophrenia 10.018
wu:fb71f10wu:fb71f100.018
pola2polymerase (DNA directed), alpha 20.018
dhfrdihydrofolate reductase0.018
ddx39aaDEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa0.018
dlg1discs, large (Drosophila) homolog 10.018
pgam2phosphoglycerate mutase 2 (muscle)0.018
nedd8neural precursor cell expressed, developmentally down-regulated 80.018
ybx1Y box binding protein 10.018
cdc7cell division cycle 7 homolog (S. cerevisiae)0.018
wnt2bbwingless-type MMTV integration site family, member 2Bb0.017
wnt5awingless-type MMTV integration site family, member 5a0.017
nrarpbnotch-regulated ankyrin repeat protein b0.017
eef2beukaryotic translation elongation factor 2b0.017
pvrl1bpoliovirus receptor-related 1b0.017
flrfleer0.016
rbl1retinoblastoma-like 1 (p107)0.016
pole2polymerase (DNA directed), epsilon 20.016
cdk7cyclin-dependent kinase 70.016
bcl2B-cell leukemia/lymphoma 20.016
tnnc1btroponin C type 1b (slow)0.016
gsnagelsolin a0.016
atp1b3bATPase, Na+/K+ transporting, beta 3b polypeptide0.016
eif3deukaryotic translation initiation factor 3, subunit D0.016
zgc:73142zgc:731420.016
atp1a3bATPase, Na+/K+ transporting, alpha 3b polypeptide0.016
atp1a1a.2ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide0.016
junjun proto-oncogene0.016
zgc:100817zgc:1008170.016
fhlafour and a half LIM domains a0.016
gnat2guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 20.016
ddx19DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast)0.015
emx2empty spiracles homeobox 20.015
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Pi3K92ECG4141 gene product from transcript CG4141-RB0.956
Ge-1CG6181 gene product from transcript CG6181-RA0.817
KhcKinesin heavy chain0.817
Ras85DRas oncogene at 85D0.789
shishibire0.777
cenG1Acentaurin gamma 1A0.745
Hel25EHelicase at 25E0.725
spn-Aspindle A0.709
Eip63EEcdysone-induced protein 63E0.702
E(z)Enhancer of zeste0.660
picpiccolo0.653
RhoGEF2CG9635 gene product from transcript CG9635-RF0.623
RhoGAP68FCG6811 gene product from transcript CG6811-RA0.595
saxsaxophone0.595
shotshort stop0.554
Rpd3CG7471 gene product from transcript CG7471-RA0.546
rokRho-kinase0.543
MoeMoesin0.520
mus309mutagen-sensitive 3090.514
Snr1Snf5-related 10.508
Rab7Rab-protein 70.499
rinrasputin0.491
Pk61CProtein kinase 61C0.489
Nup154Nucleoporin 1540.480
E(bx)Enhancer of bithorax0.473
CG8247CG8247 gene product from transcript CG8247-RB0.463
CG8155CG8155 gene product from transcript CG8155-RA0.442
lin19lin-19-like0.442
Top1Topoisomerase 10.436
gfAgiant fibre A0.427
Dhc64CDynein heavy chain 64C0.418
mbtmushroom bodies tiny0.417
ninaEneither inactivation nor afterpotential E0.415
mei-9meiotic 90.402
TER94CG2331 gene product from transcript CG2331-RA0.390
chicchickadee0.386
traltrailer hitch0.385
spn-Espindle E0.384
14-3-3epsilonCG31196 gene product from transcript CG31196-RA0.384
ChcClathrin heavy chain0.380
mus301mutagen-sensitive 3010.362
mus209mutagen-sensitive 2090.359
lgslegless0.347
MadMothers against dpp0.346
mus210mutagen-sensitive 2100.345
dysdysfusion0.343
Arf79FADP ribosylation factor 79F0.341
Sin3ACG8815 gene product from transcript CG8815-RC0.339
CG11092CG11092 gene product from transcript CG11092-RA0.336
MTF-1Metal response element-binding Transcription Factor-10.328
SpnSpinophilin0.328
Mcm5Minichromosome maintenance 50.328
piepineapple eye0.325
CalpBCalpain-B0.319
Rho1CG8416 gene product from transcript CG8416-RB0.314
AGO1Argonaute-10.311
NetBNetrin-B0.306
IswiImitation SWI0.304
CG32772CG32772 gene product from transcript CG32772-RC0.304
spn-Bspindle B0.303
CG1416CG1416 gene product from transcript CG1416-RA0.302
bazbazooka0.299
rlrolled0.297
rictorrapamycin-insensitive companion of Tor0.295
CG11107CG11107 gene product from transcript CG11107-RA0.295
Gbeta13FG protein beta-subunit 13F0.294
CG6686CG6686 gene product from transcript CG6686-RB0.294
scnyscrawny0.289
CG32479CG32479 gene product from transcript CG32479-RA0.287
Hnf4Hepatocyte nuclear factor 40.282
Galpha49BG protein alpha49B0.282
Dcr-2Dicer-20.281
pod1CG4532 gene product from transcript CG4532-RF0.280
hayhaywire0.279
staustaufen0.271
bsblistered0.270
putpunt0.267
CG14478CG14478 gene product from transcript CG14478-RA0.266
gclgerm cell-less0.265
CG4771CG4771 gene product from transcript CG4771-RA0.264
Mi-2CG8103 gene product from transcript CG8103-RA0.261
DlicDynein light intermediate chain0.258
Syx7Syntaxin 70.258
CG11376CG11376 gene product from transcript CG11376-RA0.257
mrnmarionette0.254
nebnebbish0.249
Stat92ESignal-transducer and activator of transcription protein at 92E0.247
ktokohtalo0.243
awdabnormal wing discs0.243
LIMK1LIM-kinase10.241
porinCG6647 gene product from transcript CG6647-RA0.241
alpha-Catalpha Catenin0.241
Top3alphaTopoisomerase 3alpha0.240
Src64BSrc oncogene at 64B0.235
trptransient receptor potential0.233
gammaTub23Cgamma-Tubulin at 23C0.232
cdmcadmus0.226
RecQ4CG7487 gene product from transcript CG7487-RA0.225
CG6509CG6509 gene product from transcript CG6509-RB0.223
armiarmitage0.223
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Anxa2annexin A20.293
Amphamphiphysin0.280
Lman1lectin, mannose-binding, 10.253
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.236
Psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.235
Junbjun B proto-oncogene0.227
Pfn1profilin 10.214
Rhoaras homolog gene family, member A0.207
Tpm3tropomyosin 3, gamma0.201
Tubb5tubulin, beta 50.191
Klf4Kruppel-like factor 4 (gut)0.189
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.183
Gria2glutamate receptor, ionotropic, AMPA 20.177
Cyth1cytohesin 10.168
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.157
Cd37CD37 molecule0.154
Dusp1dual specificity phosphatase 10.152
Slc25a3solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 30.147
Gipc1GIPC PDZ domain containing family, member 10.140
Atf3activating transcription factor 30.140
Hk1hexokinase 10.137
Sumo1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)0.135
Gabrb3gamma-aminobutyric acid (GABA) A receptor, beta 30.133
Rab5aRAB5A, member RAS oncogene family0.129
Myo1dmyosin ID0.122
Mapk8ip1mitogen-activated protein kinase 8 interacting protein 10.121
Eif5eukaryotic translation initiation factor 50.121
RfngRFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase0.120
Pja2praja 2, RING-H2 motif containing0.118
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.115
Arpc2actin related protein 2/3 complex, subunit 20.115
Uqcrc1ubiquinol-cytochrome c reductase core protein I0.115
Mapk3mitogen activated protein kinase 30.114
Arpc1bactin related protein 2/3 complex, subunit 1B0.112
CnbpCCHC-type zinc finger, nucleic acid binding protein0.110
Dlgap1discs, large (Drosophila) homolog-associated protein 10.109
Kcnab2potassium voltage-gated channel, shaker-related subfamily, beta member 20.107
Snap25synaptosomal-associated protein 250.106
Mgat5mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase0.105
Stxbp1syntaxin binding protein 10.104
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.104
Epas1endothelial PAS domain protein 10.104
Dnajc5DnaJ (Hsp40) homolog, subfamily C, member 50.099
Gnai3guanine nucleotide binding protein (G protein), alpha inhibiting 30.098
Saps2SAPS domain family, member 20.097
Aif1allograft inflammatory factor 10.097
Gabrg1gamma-aminobutyric acid (GABA) A receptor, gamma 10.096
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.096
Tagln2transgelin 20.095
Dlg3discs, large homolog 3 (Drosophila)0.095
Actn2actinin alpha 20.095
Acta2smooth muscle alpha-actin0.095
Casp3caspase 30.092
Kiss1rKISS1 receptor0.092
Myadmmyeloid-associated differentiation marker0.092
Smu1smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)0.087
FosFBJ osteosarcoma oncogene0.086
Cfpcomplement factor properdin0.086
Cyth3cytohesin 30.085
S100a10S100 calcium binding protein A100.084
Wdr1WD repeat domain 10.084
Mtpnmyotrophin0.083
Hist1h1ahistone cluster 1, H1a0.082
Stxbp5syntaxin binding protein 5 (tomosyn)0.082
Mbmyoglobin0.082
Arl1ADP-ribosylation factor-like 10.081
Tap2transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)0.081
Clcn2chloride channel 20.081
Zfp36zinc finger protein 360.081
Vimvimentin0.080
Jak2Janus kinase 20.078
Papolapoly (A) polymerase alpha0.078
Cops7aCOP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)0.078
SvopSV2 related protein0.078
Atp1b1ATPase, Na+/K+ transporting, beta 1 polypeptide0.077
Cskc-src tyrosine kinase0.077
NsfN-ethylmaleimide-sensitive factor0.076
Ruvbl1RuvB-like 1 (E. coli)0.076
Pafah1b2platelet-activating factor acetylhydrolase, isoform 1b, subunit 20.076
Ap2a1adaptor-related protein complex 2, alpha 1 subunit0.076
Pdclphosducin-like0.075
Prkceprotein kinase C, epsilon0.074
Bin1bridging integrator 10.074
Epn1Epsin 10.073
Fgfr1Fibroblast growth factor receptor 10.073
Sh3gl2SH3-domain GRB2-like 20.073
Sncasynuclein, alpha (non A4 component of amyloid precursor)0.073
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.073
Tcf4transcription factor 40.073
Exoc5exocyst complex component 50.072
Klf6Kruppel-like factor 60.072
Mybpc2myosin binding protein C, fast-type0.072
Slc17a7solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 70.071
Prkar1aprotein kinase, cAMP-dependent, regulatory, type I, alpha0.071
Myo1cmyosin IC0.071
Tpm4tropomyosin 40.071
Itgb1integrin, beta 10.071
Pgam2phosphoglycerate mutase 2 (muscle)0.070
Mapre1microtubule-associated protein, RP/EB family, member 10.070
Lynx1Ly6/neurotoxin 10.070
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
DHH1Dhh1p0.924
RAD52Rad52p0.922
MTR3Mtr3p0.909
PAT1Pat1p0.899
PAP2Pap2p0.842
CCR4Ccr4p0.833
SKI7Ski7p0.767
NUP60Nup60p0.751
DCP2Dcp2p0.744
RRP45Rrp45p0.731
BEM4Bem4p0.712
BCK1Bck1p0.698
POL2Pol2p0.697
RRP42Rrp42p0.693
CDC39Cdc39p0.672
KEM1Kem1p0.668
MRE11Mre11p0.653
SSL1Ssl1p0.648
BEM3Bem3p0.635
CSL4Csl4p0.611
RRP6Rrp6p0.608
RAD27Rad27p0.600
TIF4632Tif4632p0.588
AIR1Air1p0.585
SWR1Swr1p0.552
GBP2Gbp2p0.547
RRP40Rrp40p0.538
AIR2Air2p0.520
SKI2Ski2p0.517
SRP101Srp101p0.515
SKI3Ski3p0.509
EDC3Edc3p0.490
TAF6Taf6p0.477
MTR4Mtr4p0.474
TFB4Tfb4p0.472
STI1Sti1p0.469
RRP43Rrp43p0.463
DCP1Dcp1p0.456
YPT7Ypt7p0.454
CDC48Cdc48p0.452
YPT31Ypt31p0.449
ROM2Rom2p0.449
SKI6Ski6p0.438
RRP4Rrp4p0.423
CDC73Cdc73p0.419
ELG1Elg1p0.417
RPT6Rpt6p0.410
MOT2Mot2p0.408
RPB2Rpb2p0.404
PEX15Pex15p0.391
MOB1Mob1p0.387
ESP1Esp1p0.382
SUB2Sub2p0.372
RNH203Rnh203p0.372
VTA1Vta1p0.365
RNH202Rnh202p0.364
ITC1Itc1p0.363
MPP6Mpp6p0.363
STE5Ste5p0.360
STE20Ste20p0.360
YPT1Ypt1p0.358
PKH2Pkh2p0.357
KIN28Kin28p0.355
XRS2Xrs2p0.348
RAD14Rad14p0.347
PET309Pet309p0.346
PRR1Prr1p0.344
LSM2Lsm2p0.341
RAD4Rad4p0.336
TOM1Tom1p0.334
NRP1Nrp1p0.332
NOP12Nop12p0.332
NOT5Not5p0.332
RAD3Rad3p0.330
POP2Pop2p0.326
MYO4Myo4p0.323
MLP2Mlp2p0.322
RAD2Rad2p0.319
HMT1Hmt1p0.317
CDC24Cdc24p0.317
SAC3Sac3p0.316
SIR2Sir2p0.314
NAB3Nab3p0.308
AVO1Avo1p0.302
MEC1Mec1p0.296
CAF40Caf40p0.296
SGS1Sgs1p0.295
LSM1Lsm1p0.294
GPR1Gpr1p0.288
VAC7Vac7p0.285
YPT52Ypt52p0.284
TSR1Tsr1p0.279
CAK1Cak1p0.277
RAS1Ras1p0.275
DEF1Def1p0.275
STE4Ste4p0.274
NPL3Npl3p0.267
CTF4Ctf4p0.266
RRP46Rrp46p0.264
VPS21Vps21p0.264