The network for 'neuron development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

neuron development

The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.

NameDescriptionProbabilityFunc Analog Organism
egl-18Protein EGL-180.983
unc-73Protein UNC-730.936
elt-6Protein ELT-60.909
syg-1Protein SYG-10.888
egl-46Protein EGL-460.829
pha-4Protein PHA-40.821
bar-1Protein BAR-10.783
pry-1Protein PRY-10.777
ceh-20Protein CEH-200.752
sem-5Protein SEM-50.724
ain-1Protein AIN-10.719
nhr-67Protein NHR-670.704
unc-62Protein UNC-620.700
ldb-1Protein LDB-10.691
ten-1Protein TEN-10.670
vab-3Protein VAB-30.670
sma-6Protein SMA-60.650
sli-1Protein SLI-10.642
egl-15Protein EGL-150.636
sdz-28Protein SDZ-280.612
glp-1Protein GLP-10.611
egl-13Protein EGL-130.594
T28F4.1Protein T28F4.10.589
unc-42Protein UNC-420.586
let-60Protein LET-600.579
cam-1Protein CAM-10.576
unc-52Protein UNC-520.576
goa-1Protein GOA-10.565
K10D6.4Protein K10D6.40.564
unc-104Protein UNC-1040.544
daf-11Protein DAF-110.544
rpt-3Protein RPT-30.539
hlh-1Protein HLH-10.532
hbl-1Protein HBL-10.527
teg-4Protein TEG-40.521
unc-43Protein UNC-430.513
lin-12Protein LIN-120.513
sax-3Protein SAX-30.512
ida-1Protein IDA-10.510
rig-6Protein RIG-60.499
lrp-2Protein LRP-20.493
pdfr-1Protein PDFR-10.482
egl-8Protein EGL-80.474
R12E2.1Protein R12E2.10.463
egl-27Protein EGL-270.431
unc-9Protein UNC-90.418
flt-1Protein FLT-10.411
W01C8.5Protein W01C8.50.408
spc-1Protein SPC-10.405
unc-70Protein UNC-700.402
trim-9Protein TRIM-90.399
atn-1Protein ATN-10.397
unc-40Protein UNC-400.396
ceh-48Protein CEH-480.391
hmp-1Protein HMP-10.376
T27A3.1Protein T27A3.10.376
shn-1Protein SHN-10.370
mab-5Protein MAB-50.369
nhr-34Protein NHR-340.366
chd-7Protein CHD-70.362
asd-1Protein ASD-10.361
M01A10.1Protein M01A10.10.356
clk-2Protein CLK-20.355
clh-5Protein CLH-50.347
cye-1Protein CYE-10.346
smp-1Protein SMP-10.346
rpn-1Protein RPN-10.342
zip-7Protein ZIP-70.334
hlh-2Protein HLH-20.328
egl-30Protein EGL-300.327
egl-5Protein EGL-50.321
cdc-37Protein CDC-370.317
mig-15Protein MIG-150.313
mig-10Protein MIG-100.312
mig-2Protein MIG-20.311
myo-1Protein MYO-10.309
mel-28Protein MEL-280.308
pop-1Protein POP-10.308
tag-241Protein TAG-2410.308
gsp-1Protein GSP-10.307
syg-2Protein SYG-20.306
unc-6Protein UNC-60.306
enu-3Protein ENU-30.305
egg-6Protein EGG-60.300
F09A5.4Protein F09A5.40.298
rsd-2Protein RSD-20.297
R90.1Protein R90.10.294
C28H8.3Protein C28H8.30.285
mig-38Protein MIG-380.283
ect-2Protein ECT-20.283
imb-2Protein IMB-20.282
CELE_C38D4.1Protein C38D4.10.282
dpy-28Protein DPY-280.281
ajm-1Protein AJM-10.281
daf-12Protein DAF-120.279
lin-17Protein LIN-170.276
kal-1Protein KAL-10.275
peb-1Protein PEB-10.274
T24B8.3Protein T24B8.30.273
hcp-3Protein HCP-30.272
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
prdm1aPR domain containing 1a, with ZNF domain0.999
gdf6agrowth differentiation factor 6a0.997
spry4sprouty (Drosophila) homolog 40.994
lhx2bLIM homeobox 2b0.993
pax2apaired box gene 2a0.993
eya1eyes absent homolog 10.989
alcamaactivated leukocyte cell adhesion molecule a0.983
crabp2acellular retinoic acid binding protein 2, a0.981
plod3procollagen-lysine, 2-oxoglutarate 5-dioxygenase 30.981
foxi1forkhead box I10.981
cxcr4bchemokine (C-X-C motif), receptor 4b0.978
slc17a6bsolute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b0.976
robo2roundabout homolog 20.973
cntn2contactin 20.972
olig2oligodendrocyte lineage transcription factor 20.969
eng2aengrailed 2a0.967
fgf3fibroblast growth factor 30.966
neurodneurogenic differentiation0.965
elavl3ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)0.965
dpysl3dihydropyrimidinase-like 30.964
shhasonic hedgehog a0.963
jag2jagged 20.963
ift88intraflagellar transport 88 homolog0.951
atoh7atonal homolog 70.951
atoh1aatonal homolog 1a0.950
cdh23cadherin-like 230.949
fn1fibronectin 10.948
ndr2nodal-related 20.946
wnt10awingless-type MMTV integration site family, member 10a0.943
flhfloating head0.943
myhz2myosin, heavy polypeptide 2, fast muscle specific0.942
frem3Fras1 related extracellular matrix 30.940
restRE1-silencing transcription factor0.936
pcdh18bprotocadherin 18b0.931
gli1GLI-Kruppel family member 10.929
notch1anotch homolog 1a0.928
hey1hairy/enhancer-of-split related with YRPW motif 10.924
tp53tumor protein p530.923
otx5orthodenticle homolog 50.921
ptch2patched 20.919
sox9aSRY-box containing gene 9a0.911
foxp2forkhead box P20.911
hoxa1ahomeo box A1a0.909
kdrlkinase insert domain receptor like0.905
tfap2atranscription factor AP-2 alpha0.905
fstafollistatin a0.904
stmn2bstathmin-like 2b0.897
epb41l5erythrocyte membrane protein band 4.1 like 50.890
fezf2FEZ family zinc finger 20.876
nr2e1nuclear receptor subfamily 2, group E, member 10.868
sema3aasemaphorin 3aa0.864
foxh1forkhead box H10.862
lmx1b.1LIM homeobox transcription factor 1, beta 10.857
her15.1hairy and enhancer of split-related 15.10.850
lhx1aLIM homeobox 1a0.850
pitx3paired-like homeodomain transcription factor 30.848
ascl1aachaete-scute complex-like 1a (Drosophila)0.843
runx1runt-related transcription factor 10.842
otx2orthodenticle homolog 20.837
camkvbCaM kinase-like vesicle-associated b0.835
tbx1T-box 10.835
jag1bjagged 1b0.832
dlx6adistal-less homeobox gene 6a0.831
ndrg4N-myc downstream regulated gene 40.830
hand2heart and neural crest derivatives expressed transcript 20.826
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.824
atoh1batonal homolog 1b0.822
sox4aSRY-box containing gene 4a0.819
rx3retinal homeobox gene 30.819
dag1dystroglycan 10.818
pax6apaired box gene 6a0.818
csnk1a1casein kinase 1, alpha 10.816
nrp1aneuropilin 1a0.816
sox32SRY-box containing gene 320.813
her4.2hairy-related 4.20.812
tnni1altroponin I, skeletal, slow like0.806
tbx18T-box 180.805
foxd3forkhead box D30.804
rarabretinoic acid receptor, alpha b0.802
lamb2laminin, beta 2 (laminin S)0.802
otpborthopedia homolog b0.801
myhz1.1myosin, heavy polypeptide 1.1, skeletal muscle0.797
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.796
scrt2scratch homolog 2, zinc finger protein (Drosophila)0.795
irx4biroquois homeobox protein 4b0.793
lingo1aleucine rich repeat and Ig domain containing 1a0.792
ret1receptor tyrosine kinase0.792
neo1neogenin 10.788
notch3notch homolog 30.788
cdkn1ccyclin-dependent kinase inhibitor 1C (p57, Kip2)0.785
cmybtranscription factor cmyb0.784
ptprfprotein tyrosine phosphatase, receptor type, F0.783
vsx1visual system homeobox 1 homolog, chx10-like0.782
myh6myosin, heavy polypeptide 6, cardiac muscle, alpha0.780
lamc1laminin, gamma 10.775
gpr98G protein-coupled receptor 980.773
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EGFRepidermal growth factor receptor0.997
FN1fibronectin 10.991
BCAR1breast cancer anti-estrogen resistance 10.971
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.952
ATXN1ataxin 10.950
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.947
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.938
RB1retinoblastoma 10.924
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.919
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.915
QKIquaking homolog, KH domain RNA binding (mouse)0.907
FYNFYN oncogene related to SRC, FGR, YES0.882
BMI1BMI1 polycomb ring finger oncogene0.872
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.869
CREBBPCREB binding protein0.863
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.850
APPamyloid beta (A4) precursor protein0.840
DLG4discs, large homolog 4 (Drosophila)0.823
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.815
MAPTmicrotubule-associated protein tau0.783
TP53tumor protein p530.772
SMAD3SMAD family member 30.739
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.733
SMAD2SMAD family member 20.719
JUNjun proto-oncogene0.713
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.713
NCOR1nuclear receptor corepressor 10.710
HDAC1histone deacetylase 10.699
PCGF2polycomb group ring finger 20.685
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.660
EP300E1A binding protein p3000.659
FLNAfilamin A, alpha0.614
ATN1atrophin 10.606
MOBKL3MOB1, Mps One Binder kinase activator-like 3 (yeast)0.579
MAP3K5mitogen-activated protein kinase kinase kinase 50.564
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.552
HDAC2histone deacetylase 20.541
REREarginine-glutamic acid dipeptide (RE) repeats0.540
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.535
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.527
CEP170centrosomal protein 170kDa0.522
ESR1estrogen receptor 10.521
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.517
VAV1vav 1 guanine nucleotide exchange factor0.503
MDM2Mdm2 p53 binding protein homolog (mouse)0.489
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.485
PRMT1protein arginine methyltransferase 10.480
SMURF2SMAD specific E3 ubiquitin protein ligase 20.475
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.469
IGF1Rinsulin-like growth factor 1 receptor0.465
E2F1E2F transcription factor 10.459
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme0.443
MMP14matrix metallopeptidase 14 (membrane-inserted)0.440
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.438
SUMO1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)0.428
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)0.423
EPS8epidermal growth factor receptor pathway substrate 80.421
SYKspleen tyrosine kinase0.411
ITSN1intersectin 1 (SH3 domain protein)0.400
NCAM1neural cell adhesion molecule 10.400
GRB2growth factor receptor-bound protein 20.395
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.394
FASLGFas ligand (TNF superfamily, member 6)0.387
CREB1cAMP responsive element binding protein 10.387
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.366
FGFR1fibroblast growth factor receptor 10.365
MAPK8mitogen-activated protein kinase 80.365
NR4A1nuclear receptor subfamily 4, group A, member 10.361
METmet proto-oncogene (hepatocyte growth factor receptor)0.358
TAL1T-cell acute lymphocytic leukemia 10.345
STK3serine/threonine kinase 30.345
PTPN1protein tyrosine phosphatase, non-receptor type 10.335
MTORmechanistic target of rapamycin (serine/threonine kinase)0.329
JAG1jagged 10.323
RING1ring finger protein 10.321
SMARCA5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 50.312
ARandrogen receptor0.312
SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)0.307
GSK3Bglycogen synthase kinase 3 beta0.302
FOSFBJ murine osteosarcoma viral oncogene homolog0.293
NRXN1neurexin 10.292
TRRAPtransformation/transcription domain-associated protein0.290
VHLvon Hippel-Lindau tumor suppressor0.288
ACTBactin, beta0.287
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.282
ARID1AAT rich interactive domain 1A (SWI-like)0.280
DAG1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.279
FHL2four and a half LIM domains 20.279
FNBP1Lformin binding protein 1-like0.277
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.277
HSPG2heparan sulfate proteoglycan 20.269
LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.269
DTNAdystrobrevin, alpha0.268
FBLN1fibulin 10.268
KCNA1potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)0.266
RPS6KA6ribosomal protein S6 kinase, 90kDa, polypeptide 60.266
RANBP9RAN binding protein 90.265
CFL1cofilin 1 (non-muscle)0.261
GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.261
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Fgfr2fibroblast growth factor receptor 20.908
Nrxn1neurexin 10.861
Calcrlcalcitonin receptor-like0.768
Lin7blin-7 homolog b (C. elegans)0.720
Nrcamneuronal cell adhesion molecule0.696
Gria2glutamate receptor, ionotropic, AMPA 20.668
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.658
Trib1tribbles homolog 1 (Drosophila)0.628
Actbactin, beta0.625
Sncbsynuclein, beta0.621
Tgfbr2transforming growth factor, beta receptor II0.618
Apba1amyloid beta (A4) precursor protein-binding, family A, member 10.607
Grm5glutamate receptor, metabotropic 50.603
Dlgap1discs, large (Drosophila) homolog-associated protein 10.583
Dlgap3discs, large (Drosophila) homolog-associated protein 30.568
Aqp4aquaporin 40.563
Strnstriatin, calmodulin binding protein0.557
Itgamintegrin, alpha M0.542
Neflneurofilament, light polypeptide0.540
Atp2b3ATPase, Ca++ transporting, plasma membrane 30.507
Map1bmicrotubule-associated protein 1B0.507
Gria4glutamate receptor, ionotrophic, AMPA 40.482
Map2microtubule-associated protein 20.481
Tmod2tropomodulin 20.472
Socs3suppressor of cytokine signaling 30.470
Grip1glutamate receptor interacting protein 10.466
Gdf11growth differentiation factor 110.459
Nedd4neural precursor cell expressed, developmentally down-regulated 40.452
Syngap1synaptic Ras GTPase activating protein 1 homolog (rat)0.451
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.447
Hckhemopoietic cell kinase0.441
Gabra4gamma-aminobutyric acid (GABA) A receptor, alpha 40.426
Camk4calcium/calmodulin-dependent protein kinase IV0.424
Scn3asodium channel, voltage-gated, type III, alpha0.424
Atf3activating transcription factor 30.422
Nrxn3neurexin 30.412
Olfml2bolfactomedin-like 2B0.406
Syt4synaptotagmin IV0.403
Plauplasminogen activator, urokinase0.403
Cnksr2connector enhancer of kinase suppressor of Ras 20.403
Fgd4FYVE, RhoGEF and PH domain containing 40.400
Gnao1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O0.396
Arnt2aryl hydrocarbon receptor nuclear translocator 20.395
Mmp12matrix metallopeptidase 120.389
Nfianuclear factor I/A0.380
Prkcgprotein kinase C, gamma0.378
Gabrb1gamma-aminobutyric acid (GABA) A receptor, beta 10.378
Myh10myosin, heavy chain 10, non-muscle0.375
Dlg4discs, large homolog 4 (Drosophila)0.373
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.371
Nr4a2nuclear receptor subfamily 4, group A, member 20.367
Dlg3discs, large homolog 3 (Drosophila)0.367
Calm3calmodulin 30.364
Ptprdprotein tyrosine phosphatase, receptor type, D0.363
Gna12guanine nucleotide binding protein (G protein) alpha 120.362
Kcnh1potassium voltage-gated channel, subfamily H (eag-related), member 10.360
Hoxa2homeo box A20.359
St18suppression of tumorigenicity 180.359
Cyth1cytohesin 10.359
Cd4Cd4 molecule0.356
Pcsk2proprotein convertase subtilisin/kexin type 20.356
Gabra5gamma-aminobutyric acid (GABA) A receptor, alpha 50.353
Slc24a2solute carrier family 24 (sodium/potassium/calcium exchanger), member 20.350
Gabra1gamma-aminobutyric acid (GABA) A receptor, alpha 10.348
Notch1Notch homolog 1, translocation-associated (Drosophila)0.346
Kcnt1potassium channel, subfamily T, member 10.344
Pip4k2bphosphatidylinositol-5-phosphate 4-kinase, type II, beta0.343
Jak1Janus kinase 10.336
Nrg1neuregulin 10.335
Nfibnuclear factor I/B0.334
Npy1rneuropeptide Y receptor Y10.334
Inpp5dinositol polyphosphate-5-phosphatase D0.334
Gabrb3gamma-aminobutyric acid (GABA) A receptor, beta 30.329
Slit3slit homolog 3 (Drosophila)0.329
Ccl2chemokine (C-C motif) ligand 20.322
Pde5aphosphodiesterase 5A, cGMP-specific0.322
Anxa2annexin A20.318
Tbx2T-box 20.318
Pde4bphosphodiesterase 4B, cAMP specific0.315
Chrna4cholinergic receptor, nicotinic, alpha 40.313
Clic4chloride intracellular channel 40.311
Pls3plastin 3 (T-isoform)0.310
Hk1hexokinase 10.308
Tagln3transgelin 30.302
Slc4a3solute carrier family 4 (anion exchanger), member 30.302
Spire1spire homolog 1 (Drosophila)0.300
Map1amicrotubule-associated protein 1A0.299
Nlgn1neuroligin 10.297
Lzts1leucine zipper, putative tumor suppressor 10.296
Cadm1cell adhesion molecule 10.292
Adrb1adrenergic, beta-1-, receptor0.291
Tcf4transcription factor 40.290
Inainternexin neuronal intermediate filament protein, alpha0.289
Dchs1dachsous 1 (Drosophila)0.289
Cplx2complexin 20.288
Rasgrf1RAS protein-specific guanine nucleotide-releasing factor 10.287
Ednrbendothelin receptor type B0.283
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.282
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism