The network for 'embryo development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

embryo development

The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.

NameDescriptionProbabilityFunc Analog Organism
mom-2Protein MOM-20.998
egl-18Protein EGL-180.997
rnr-1Protein RNR-10.997
pal-1Protein PAL-10.994
dlc-1Protein DLC-10.994
nhr-2Protein NHR-20.991
scc-1Protein SCC-10.990
his-45Protein HIS-450.990
eef-1A.1Protein EEF-1A.10.989
mes-3Protein MES-30.989
his-64Protein HIS-640.989
F01G4.6Protein F01G4.60.989
prp-3Protein PRP-30.989
swd-2.2Protein SWD-2.20.987
mcm-7Protein MCM-70.987
stip-1Protein STIP-10.984
sas-5Protein SAS-50.984
vab-3Protein VAB-30.983
san-1Protein SAN-10.983
his-46Protein HIS-460.983
npp-11Protein NPP-110.982
hcp-3Protein HCP-30.982
dao-5Protein DAO-50.982
rars-1Protein RARS-10.981
let-99Protein LET-990.981
par-5Protein PAR-50.981
tag-170Protein TAG-1700.980
his-68Protein HIS-680.980
rpl-4Protein RPL-40.980
mrps-18BProtein MRPS-18B0.978
mig-5Protein MIG-50.978
skr-2Protein SKR-20.977
skr-7Protein SKR-70.977
cam-1Protein CAM-10.976
icd-1Protein ICD-10.975
tba-1Protein TBA-10.974
pch-2Protein PCH-20.974
elt-6Protein ELT-60.973
asb-2Protein ASB-20.972
hsp-1Protein HSP-10.972
his-16Protein HIS-160.972
aos-1Protein AOS-10.970
klp-16Protein KLP-160.969
rbx-1Protein RBX-10.969
pab-1Protein PAB-10.968
flh-1Protein FLH-10.968
his-5Protein HIS-50.968
his-62Protein HIS-620.965
npp-1Protein NPP-10.965
bir-1Protein BIR-10.964
hcp-4Protein HCP-40.964
mig-6Protein MIG-60.963
abce-1Protein ABCE-10.961
ndc-80Protein NDC-800.961
fkb-6Protein FKB-60.961
spn-4Protein SPN-40.960
patr-1Protein PATR-10.959
apc-11Protein APC-110.959
epg-8Protein EPG-80.958
ubc-12Protein UBC-120.957
F53B7.3Protein F53B7.30.957
T11G6.8Protein T11G6.80.956
snr-5Protein SNR-50.956
C44E4.4Protein C44E4.40.953
ran-1Protein RAN-10.953
pqn-59Protein PQN-590.953
bub-1Protein BUB-10.952
ptr-2Protein PTR-20.952
pos-1Protein POS-10.952
rack-1Protein RACK-10.951
rpl-7Protein RPL-70.951
W08E12.7Protein W08E12.70.951
mel-11Protein MEL-110.951
prg-1Protein PRG-10.950
sbds-1Protein SBDS-10.950
unc-37Protein UNC-370.950
ify-1Protein IFY-10.949
dsh-2Protein DSH-20.949
hcp-1Protein HCP-10.948
his-1Protein HIS-10.948
lsy-22Protein LSY-220.948
mat-3Protein MAT-30.946
pfd-1Protein PFD-10.946
mcm-6Protein MCM-60.945
npp-15Protein NPP-150.944
Y110A7A.4Protein Y110A7A.40.944
dhfr-1Protein DHFR-10.944
H28O16.1Protein H28O16.10.944
hpo-35Protein HPO-350.943
dlat-1Protein DLAT-10.942
pat-4Protein PAT-40.942
hda-1Protein HDA-10.941
his-31Protein HIS-310.941
Y47D3A.29Protein Y47D3A.290.941
nap-1Protein NAP-10.941
brc-1Protein BRC-10.940
skn-1Protein SKN-10.939
rad-50Protein RAD-500.939
CELE_F19F10.9Protein F19F10.90.938
wdr-46Protein WDR-460.937
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
SRSF1serine/arginine-rich splicing factor 10.997
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.996
TP53tumor protein p530.993
EGFRepidermal growth factor receptor0.991
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.990
FN1fibronectin 10.989
HDAC1histone deacetylase 10.989
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.979
HNRNPCheterogeneous nuclear ribonucleoprotein C (C1/C2)0.976
HDAC2histone deacetylase 20.973
BRCA1breast cancer 1, early onset0.972
UBCubiquitin C0.971
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.971
ICT1immature colon carcinoma transcript 10.968
HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 10.965
C1QBPcomplement component 1, q subcomponent binding protein0.965
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.964
KPNA2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)0.962
SMAD2SMAD family member 20.949
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.946
ILF3interleukin enhancer binding factor 3, 90kDa0.946
SMAD4SMAD family member 40.937
SMAD3SMAD family member 30.936
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.936
ATF2activating transcription factor 20.933
DHX15DEAH (Asp-Glu-Ala-His) box polypeptide 150.926
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.916
MAPK14mitogen-activated protein kinase 140.914
CSE1LCSE1 chromosome segregation 1-like (yeast)0.909
COPS5COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)0.906
RPS6ribosomal protein S60.904
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.893
SRSF7serine/arginine-rich splicing factor 70.891
SUMO1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)0.886
HSPA9heat shock 70kDa protein 9 (mortalin)0.873
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.870
RPL6ribosomal protein L60.868
TCP1t-complex 10.867
CSNK2A1casein kinase 2, alpha 1 polypeptide0.859
NPM1nucleophosmin (nucleolar phosphoprotein B23, numatrin)0.855
EP300E1A binding protein p3000.855
APCadenomatous polyposis coli0.838
CSNK2Bcasein kinase 2, beta polypeptide0.835
JUNjun proto-oncogene0.831
SRPK2SRSF protein kinase 20.830
SRSF2serine/arginine-rich splicing factor 20.829
ESR1estrogen receptor 10.824
CUL3cullin 30.822
MDM2Mdm2 p53 binding protein homolog (mouse)0.813
PCGF2polycomb group ring finger 20.809
CREBBPCREB binding protein0.808
SYNCRIPsynaptotagmin binding, cytoplasmic RNA interacting protein0.799
SRSF3serine/arginine-rich splicing factor 30.783
MRPL3mitochondrial ribosomal protein L30.776
USP7ubiquitin specific peptidase 7 (herpes virus-associated)0.773
RPS8ribosomal protein S80.771
RPL14ribosomal protein L140.755
PRPF40APRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)0.750
PGK1phosphoglycerate kinase 10.746
CDC23cell division cycle 23 homolog (S. cerevisiae)0.738
PHBprohibitin0.737
TARDBPTAR DNA binding protein0.736
SRPK1SRSF protein kinase 10.716
IQGAP1IQ motif containing GTPase activating protein 10.715
RB1retinoblastoma 10.708
DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked0.706
HNRNPUL1heterogeneous nuclear ribonucleoprotein U-like 10.702
PSMB5proteasome (prosome, macropain) subunit, beta type, 50.702
CDC27cell division cycle 27 homolog (S. cerevisiae)0.696
PPP1R12Aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.695
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.693
RHOAras homolog gene family, member A0.692
FLNAfilamin A, alpha0.691
RFC4replication factor C (activator 1) 4, 37kDa0.684
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.671
COL1A1collagen, type I, alpha 10.669
PRKDCprotein kinase, DNA-activated, catalytic polypeptide0.669
PSEN1presenilin 10.665
CDK2cyclin-dependent kinase 20.662
CYC1cytochrome c-10.660
MCM3minichromosome maintenance complex component 30.649
SF3B1splicing factor 3b, subunit 1, 155kDa0.648
NCOR1nuclear receptor corepressor 10.643
EIF4A3eukaryotic translation initiation factor 4A30.643
FGFR1fibroblast growth factor receptor 10.639
ACTR3ARP3 actin-related protein 3 homolog (yeast)0.632
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.630
NUDCnuclear distribution gene C homolog (A. nidulans)0.625
EPS15epidermal growth factor receptor pathway substrate 150.621
CCT2chaperonin containing TCP1, subunit 2 (beta)0.612
RPS4Xribosomal protein S4, X-linked0.608
SUMO2SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)0.606
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.606
DAXXdeath-domain associated protein0.603
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.603
CCT5chaperonin containing TCP1, subunit 5 (epsilon)0.600
NDUFS3NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)0.598
U2AF1U2 small nuclear RNA auxiliary factor 10.589
SEC23ASec23 homolog A (S. cerevisiae)0.588
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.584
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Tgfbr2transforming growth factor, beta receptor II0.264
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.224
Smad7SMAD family member 70.187
Psgb1pregnancy-specific beta 1-glycoprotein0.186
Sirpasignal-regulatory protein alpha0.149
Slc5a1solute carrier family 5 (sodium/glucose cotransporter), member 10.130
Col12a1collagen, type XII, alpha 10.126
CnbpCCHC-type zinc finger, nucleic acid binding protein0.118
Psmb3proteasome (prosome, macropain) subunit, beta type 30.110
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.110
Irs1insulin receptor substrate 10.100
Cald1caldesmon 10.097
Erbb4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.095
Trim47tripartite motif-containing 470.086
Elnelastin0.082
Tcfe2atranscription factor E2a0.079
Actr3ARP3 actin-related protein 3 homolog (yeast)0.079
Myh9myosin, heavy chain 9, non-muscle0.078
Actbactin, beta0.076
Tarsthreonyl-tRNA synthetase0.075
Nek9NIMA (never in mitosis gene a)- related kinase 90.073
Sdc3syndecan 30.073
Col5a2collagen, type V, alpha 20.073
Lamc1laminin, gamma 10.073
Dusp1dual specificity phosphatase 10.072
Fgfr2fibroblast growth factor receptor 20.072
Metmet proto-oncogene0.071
Bcl2B-cell CLL/lymphoma 20.071
Egr2early growth response 20.071
Rhobras homolog gene family, member B0.071
Rararetinoic acid receptor, alpha0.070
Fn1fibronectin 10.069
Flt1FMS-related tyrosine kinase 10.069
Psma5proteasome (prosome, macropain) subunit, alpha type 50.068
Acvr1activin A receptor, type I0.066
Tpm3tropomyosin 3, gamma0.064
Serpinh1serine (or cysteine) peptidase inhibitor, clade H, member 10.061
Ets1v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)0.060
Nedd4neural precursor cell expressed, developmentally down-regulated 40.059
Col1a2collagen, type I, alpha 20.058
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.058
Foxd3forkhead box D30.057
Myo1bmyosin Ib0.056
Jak1Janus kinase 10.056
Neurog1neurogenin 10.056
Tubb5tubulin, beta 50.055
Hoxb7homeo box B70.054
Clic4chloride intracellular channel 40.053
Tp53tumor protein p530.052
Foxc2forkhead box C20.052
Flnafilamin A, alpha0.051
Dchs1dachsous 1 (Drosophila)0.051
Akt1v-akt murine thymoma viral oncogene homolog 10.051
Krt18keratin 180.051
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.051
Rhoaras homolog gene family, member A0.050
Wdr26WD repeat domain 260.050
Sfrs2splicing factor, arginine/serine-rich 20.049
Prrx1paired related homeobox 10.049
Dapk3death-associated protein kinase 30.049
Sox17SRY (sex determining region Y)-box 170.049
Gastgastrin0.049
Acta2smooth muscle alpha-actin0.049
Rap1bRAP1B, member of RAS oncogene family0.048
GraspGRP1 (general receptor for phosphoinositides 1)-associated scaffold protein0.048
Psma4proteasome (prosome, macropain) subunit, alpha type 40.048
Abi1abl-interactor 10.048
Ptpn12protein tyrosine phosphatase, non-receptor type 120.048
Junbjun B proto-oncogene0.047
Myo1emyosin IE0.047
Bgnbiglycan0.046
Ptprcprotein tyrosine phosphatase, receptor type, C0.046
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.046
Arih1ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)0.045
KlKlotho0.045
Psma3proteasome (prosome, macropain) subunit, alpha type 30.045
Dlg1discs, large homolog 1 (Drosophila)0.045
Timp3TIMP metallopeptidase inhibitor 30.045
Lig3ligase III, DNA, ATP-dependent0.043
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.043
Dact3dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)0.043
Gnai2guanine nucleotide binding protein (G protein), alpha inhibiting 20.043
Aqp2aquaporin 2 (collecting duct)0.043
Ptger4prostaglandin E receptor 4 (subtype EP4)0.042
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.042
Ptpn1protein tyrosine phosphatase, non-receptor type 10.041
Bmp6bone morphogenetic protein 60.041
Nab1Ngfi-A binding protein 10.041
Ccnb2cyclin B20.041
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.041
Chrngcholinergic receptor, nicotinic, gamma0.041
Cand1cullin-associated and neddylation-dissociated 10.040
Runx1runt-related transcription factor 10.040
JunJun oncogene0.039
Gja5gap junction protein, alpha 50.039
Prkchprotein kinase C, eta0.039
Nsfl1cNSFL1 (p97) cofactor (p47)0.039
Pcsk5proprotein convertase subtilisin/kexin type 50.039
Nr4a1nuclear receptor subfamily 4, group A, member 10.039
Ins2insulin 20.039
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism