The network for 'positive regulation of neurogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of neurogenesis

Any process that activates or increases the frequency, rate or extent of neurogenesis, the origin and formation of neurons.

NameDescriptionProbabilityFunc Analog Organism
pha-4Protein PHA-40.921
hlh-2Protein HLH-20.908
elt-6Protein ELT-60.889
nhr-67Protein NHR-670.753
ten-1Protein TEN-10.683
bar-1Protein BAR-10.572
egl-18Protein EGL-180.546
lin-17Protein LIN-170.478
let-60Protein LET-600.408
mpk-1Protein MPK-10.358
unc-32Protein UNC-320.351
pry-1Protein PRY-10.351
flt-1Protein FLT-10.345
egl-27Protein EGL-270.322
madf-5Protein MADF-50.308
lit-1Protein LIT-10.291
rhgf-2Protein RHGF-20.290
sem-5Protein SEM-50.286
goa-1Protein GOA-10.284
eps-8Protein EPS-80.271
egl-46Protein EGL-460.267
glp-1Protein GLP-10.263
R10E12.2Protein R10E12.20.262
hnd-1Protein HND-10.254
etr-1Protein ETR-10.248
Y82E9BR.18Protein Y82E9BR.180.234
unc-62Protein UNC-620.230
syd-2Protein SYD-20.226
igcm-3Protein IGCM-30.224
ztf-2Protein ZTF-20.222
par-5Protein PAR-50.216
lag-1Protein LAG-10.208
elc-1Protein ELC-10.207
tmc-2Protein TMC-20.207
pdfr-1Protein PDFR-10.194
tax-6Protein TAX-60.189
swsn-4Protein SWSN-40.188
egl-30Protein EGL-300.186
sur-2Protein SUR-20.185
F21A10.2Protein F21A10.20.175
pig-1Protein PIG-10.170
gsp-1Protein GSP-10.169
unc-40Protein UNC-400.162
unc-70Protein UNC-700.158
cdc-42Protein CDC-420.157
cnd-1Protein CND-10.156
eor-1Protein EOR-10.154
eor-2Protein EOR-20.151
cam-1Protein CAM-10.150
hlh-1Protein HLH-10.150
pct-1Protein PCT-10.146
vab-3Protein VAB-30.138
ncam-1Protein NCAM-10.137
F12F6.1Protein F12F6.10.135
ptp-3Protein PTP-30.135
F46H5.7Protein F46H5.70.133
sli-1Protein SLI-10.133
tbb-4Protein TBB-40.132
hmg-1.2Protein HMG-1.20.128
pkg-1Protein PKG-10.128
mel-11Protein MEL-110.128
lir-1Protein LIR-10.127
cit-1.1Protein CIT-1.10.125
sas-5Protein SAS-50.125
csnk-1Protein CSNK-10.122
sel-7Protein SEL-70.122
K08E3.5Protein K08E3.50.117
trim-9Protein TRIM-90.116
ajm-1Protein AJM-10.115
lat-1Protein LAT-10.114
F58H1.5Protein F58H1.50.114
bro-1Protein BRO-10.112
gla-3Protein GLA-30.112
syg-1Protein SYG-10.112
pat-3Protein PAT-30.112
epn-1Protein EPN-10.111
hmp-1Protein HMP-10.110
afd-1Protein AFD-10.110
hgrs-1Protein HGRS-10.109
ceh-20Protein CEH-200.109
gei-18Protein GEI-180.108
ztf-19Protein ZTF-190.108
daf-12Protein DAF-120.107
lin-59Protein LIN-590.106
ehs-1Protein EHS-10.106
F32A5.3Protein F32A5.30.106
F11D5.1Protein F11D5.10.106
unc-42Protein UNC-420.105
tag-343Protein TAG-3430.104
unc-104Protein UNC-1040.104
sel-11Protein SEL-110.103
dkf-1Protein DKF-10.101
W09D6.5Protein W09D6.50.101
mep-1Protein MEP-10.100
ahr-1Protein AHR-10.099
cdh-3Protein CDH-30.098
sdz-28Protein SDZ-280.097
cye-1Protein CYE-10.097
egl-13Protein EGL-130.096
smc-4Protein SMC-40.096
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
ascl1aachaete-scute complex-like 1a (Drosophila)0.935
alcamaactivated leukocyte cell adhesion molecule a0.848
bmp2bbone morphogenetic protein 2b0.769
cdh2cadherin 2, neuronal0.653
pax2apaired box gene 2a0.648
fgf8afibroblast growth factor 8 a0.606
robo3roundabout homolog 30.492
gli1GLI-Kruppel family member 10.490
dlx5adistal-less homeobox gene 5a0.433
evx1even-skipped homeobox 10.357
phox2apaired-like homeobox 2a0.318
ptf1apancreas specific transcription factor, 1a0.315
nrp2bneuropilin 2b0.312
atoh1aatonal homolog 1a0.296
neurodneurogenic differentiation0.293
neo1neogenin 10.277
gli2aGLI-Kruppel family member GLI2a0.275
tbx1T-box 10.246
tcf7l1atranscription factor 7-like 1a (T-cell specific, HMG-box)0.242
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.183
metmet proto-oncogene (hepatocyte growth factor receptor)0.179
col2a1acollagen type II, alpha-1a0.160
foxd3forkhead box D30.160
foxa1forkhead box A10.143
rx3retinal homeobox gene 30.138
gata6GATA-binding protein 60.129
lamb1alaminin, beta 1a0.122
foxa2forkhead box A20.121
elavl3ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)0.118
wnt11wingless-type MMTV integration site family, member 110.110
thtyrosine hydroxylase0.109
hey1hairy/enhancer-of-split related with YRPW motif 10.105
olig2oligodendrocyte lineage transcription factor 20.104
bocbrother of CDO0.101
slc17a6bsolute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b0.099
nkx2.2aNK2 transcription factor related 2a0.099
gata2aGATA-binding protein 2a0.098
pea3ETS-domain transcription factor pea30.098
otpborthopedia homolog b0.092
pdlim4PDZ and LIM domain 40.090
neurog1neurogenin 10.090
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.086
fgf3fibroblast growth factor 30.085
gdnfglial cell derived neurotrophic factor0.083
her6hairy-related 60.083
pax6apaired box gene 6a0.082
myf5myogenic factor 50.080
col4a5collagen, type IV, alpha 5 (Alport syndrome)0.077
egr2bearly growth response 2b0.077
spry4sprouty (Drosophila) homolog 40.074
aldh1a2aldehyde dehydrogenase 1 family, member A20.073
pvrl1bpoliovirus receptor-related 1b0.073
pafah1b1aplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a0.073
lmx1b.1LIM homeobox transcription factor 1, beta 10.073
mpzmyelin protein zero0.073
gata5GATA-binding protein 50.071
nrp2aneuropilin 2a0.071
hlxb9lahomeo box HB9 like a0.071
fstl1bfollistatin-like 1b0.067
tp53tumor protein p530.067
efnb2aephrin B2a0.065
gsnagelsolin a0.064
angptl2angiopoietin-like 20.063
bnc1basonuclin 10.062
onecutlone cut domain, family member, like0.062
diaph2diaphanous homolog 2 (Drosophila)0.061
zbtb4zinc finger and BTB domain containing 40.060
wnt11rwingless-type MMTV integration site family, member 11, related0.059
fgfr4fibroblast growth factor receptor 40.059
nrp1aneuropilin 1a0.058
bmp4bone morphogenetic protein 40.057
dccdeleted in colorectal carcinoma0.056
pcsk5bproprotein convertase subtilisin/kexin type 5b0.056
arxaristaless related homeobox0.055
fgf10afibroblast growth factor 10a0.054
otx2orthodenticle homolog 20.053
dlx3bdistal-less homeobox gene 3b0.052
pax8paired box gene 80.052
otx5orthodenticle homolog 50.051
gria3bglutamate receptor, ionotrophic, AMPA 3b0.051
prickle1bprickle homolog 1 (Drosophila) b0.051
sox9aSRY-box containing gene 9a0.050
prrx1apaired related homeobox 1a0.049
npy8brneuropeptide Y receptor Y8b0.049
foxl1forkhead box L10.049
dusp6dual specificity phosphatase 60.048
pou1f1POU domain, class 1, transcription factor 10.048
axin2axin 2 (conductin, axil)0.047
m17IL-6 subfamily cytokine M170.046
gfra1agdnf family receptor alpha 1a0.045
tal1T-cell acute lymphocytic leukemia 10.045
pitx3paired-like homeodomain transcription factor 30.045
foxi1forkhead box I10.045
trpm7transient receptor potential cation channel, subfamily M, member 70.045
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
E(spl)Enhancer of split0.879
aopanterior open0.878
Ras85DRas oncogene at 85D0.826
CapsCalcium activated protein for secretion0.735
robo3CG5423 gene product from transcript CG5423-RA0.701
phlpole hole0.599
abd-Aabdominal A0.551
Dap160Dynamin associated protein 1600.498
Liprin-alphaCG11199 gene product from transcript CG11199-RB0.493
slp1sloppy paired 10.486
EgfrEpidermal growth factor receptor0.472
SosSon of sevenless0.465
CycACyclin A0.458
InRInsulin-like receptor0.456
poloCG12306 gene product from transcript CG12306-RA0.438
Sema-1aCG18405 gene product from transcript CG18405-RD0.416
Hr51Hormone receptor 510.399
ctpcut up0.375
JraJun-related antigen0.367
emsempty spiracles0.358
HLHmgammaE(spl) region transcript mgamma0.350
CkIIalphaCasein kinase II alpha subunit0.349
rapretina aberrant in pattern0.326
HLHm7E(spl) region transcript m70.311
DscamDown syndrome cell adhesion molecule0.271
HLHmdeltaE(spl) region transcript mdelta0.256
Pi3K92ECG4141 gene product from transcript CG4141-RB0.253
gcmglial cells missing0.253
amosabsent MD neurons and olfactory sensilla0.250
HLHm5E(spl) region transcript m50.243
AblAbl tyrosine kinase0.238
shotshort stop0.230
vvlventral veins lacking0.223
Bj1Bj1 protein0.206
Stat92ESignal-transducer and activator of transcription protein at 92E0.176
idaimaginal discs arrested0.175
stanstarry night0.174
spensplit ends0.160
jebjelly belly0.155
numbCG3779 gene product from transcript CG3779-RB0.152
Pk61CProtein kinase 61C0.151
Src42ASrc oncogene at 42A0.142
rictorrapamycin-insensitive companion of Tor0.142
TBPHCG10327 gene product from transcript CG10327-RC0.142
stumpsCG31317 gene product from transcript CG31317-RC0.134
trioCG18214 gene product from transcript CG18214-RA0.132
fkhfork head0.131
zfh1Zn finger homeodomain 10.130
CG11555CG11555 gene product from transcript CG11555-RA0.129
katanin-60katanin 600.128
AlkCG8250 gene product from transcript CG8250-RA0.126
argosCG4531 gene product from transcript CG4531-RA0.117
lolalongitudinals lacking0.115
EcREcdysone receptor0.112
cindrCIN85 and CD2AP orthologue0.109
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)1.000
EGFRepidermal growth factor receptor1.000
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.991
FYNFYN oncogene related to SRC, FGR, YES0.989
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.988
GRB2growth factor receptor-bound protein 20.978
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.971
ATXN1ataxin 10.966
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.946
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.931
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.919
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.896
SPRR2Asmall proline-rich protein 2A0.878
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.854
NCK1NCK adaptor protein 10.812
METmet proto-oncogene (hepatocyte growth factor receptor)0.792
LCKlymphocyte-specific protein tyrosine kinase0.778
BCAR1breast cancer anti-estrogen resistance 10.757
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.756
NCOR1nuclear receptor corepressor 10.733
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.723
CREBBPCREB binding protein0.700
DNM1dynamin 10.681
TNK2tyrosine kinase, non-receptor, 20.678
PTPN1protein tyrosine phosphatase, non-receptor type 10.636
SOS1son of sevenless homolog 1 (Drosophila)0.614
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.609
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.588
PLCG1phospholipase C, gamma 10.548
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.494
NTRK1neurotrophic tyrosine kinase, receptor, type 10.482
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.476
LATlinker for activation of T cells0.461
SHC1SHC (Src homology 2 domain containing) transforming protein 10.453
HDAC2histone deacetylase 20.452
FGFR1fibroblast growth factor receptor 10.425
VEGFAvascular endothelial growth factor A0.385
MAPK1mitogen-activated protein kinase 10.378
TAL1T-cell acute lymphocytic leukemia 10.368
SIN3ASIN3 homolog A, transcription regulator (yeast)0.366
APLFaprataxin and PNKP like factor0.360
NTRK3neurotrophic tyrosine kinase, receptor, type 30.353
IER3immediate early response 30.345
LNX1ligand of numb-protein X 10.321
DHX30DEAH (Asp-Glu-Ala-His) box polypeptide 300.308
RUNX1runt-related transcription factor 10.296
MAPTmicrotubule-associated protein tau0.290
CREB1cAMP responsive element binding protein 10.281
POU3F2POU class 3 homeobox 20.277
ESR1estrogen receptor 10.269
DTNAdystrobrevin, alpha0.267
ARandrogen receptor0.267
HDAC1histone deacetylase 10.257
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.245
CCR5chemokine (C-C motif) receptor 50.243
PTPRCprotein tyrosine phosphatase, receptor type, C0.234
MYOD1myogenic differentiation 10.234
SMAD4SMAD family member 40.231
GRB7growth factor receptor-bound protein 70.230
CTBP1C-terminal binding protein 10.228
PLAUplasminogen activator, urokinase0.215
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.210
NCF1neutrophil cytosolic factor 10.210
DAG1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.209
MAP2K1mitogen-activated protein kinase kinase 10.206
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.203
TRIOtriple functional domain (PTPRF interacting)0.200
TRIM33tripartite motif containing 330.194
PAX3paired box 30.194
ZNF746zinc finger protein 7460.194
GAB1GRB2-associated binding protein 10.191
BMPR1Abone morphogenetic protein receptor, type IA0.190
TBX5T-box 50.187
SOX11SRY (sex determining region Y)-box 110.187
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.184
ARHGEF2Rho/Rac guanine nucleotide exchange factor (GEF) 20.181
GH1growth hormone 10.180
CSH1chorionic somatomammotropin hormone 1 (placental lactogen)0.179
QKIquaking homolog, KH domain RNA binding (mouse)0.176
FGF1fibroblast growth factor 1 (acidic)0.168
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.166
SH3GL2SH3-domain GRB2-like 20.161
MMP16matrix metallopeptidase 16 (membrane-inserted)0.157
AXIN1axin 10.152
TCF4transcription factor 40.149
HMGA2high mobility group AT-hook 20.149
PRKCEprotein kinase C, epsilon0.147
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.142
NR4A1nuclear receptor subfamily 4, group A, member 10.142
CAV1caveolin 1, caveolae protein, 22kDa0.139
ITGB4integrin, beta 40.138
PRKCAprotein kinase C, alpha0.135
PPP1R12Aprotein phosphatase 1, regulatory (inhibitor) subunit 12A0.135
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.132
RAPGEF2Rap guanine nucleotide exchange factor (GEF) 20.131
CNKSR2connector enhancer of kinase suppressor of Ras 20.126
FASLGFas ligand (TNF superfamily, member 6)0.125
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Dlgap1discs, large (Drosophila) homolog-associated protein 10.596
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.509
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.487
Slco2a1solute carrier organic anion transporter family, member 2a10.430
Anxa5annexin A50.414
Bcl2B-cell CLL/lymphoma 20.386
Ccl2chemokine (C-C motif) ligand 20.357
Cacna1acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.342
Itgamintegrin, alpha M0.338
Jak1Janus kinase 10.313
Nrxn1neurexin 10.298
Odf1outer dense fiber of sperm tails 10.284
Fgfr2fibroblast growth factor receptor 20.267
Syngap1synaptic Ras GTPase activating protein 1 homolog (rat)0.264
Atp2b3ATPase, Ca++ transporting, plasma membrane 30.262
Il1ainterleukin 1 alpha0.262
Neflneurofilament, light polypeptide0.243
Dlgap3discs, large (Drosophila) homolog-associated protein 30.243
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.236
Il1binterleukin 1 beta0.236
Prkceprotein kinase C, epsilon0.228
Rap1bRAP1B, member of RAS oncogene family0.228
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.225
Nfianuclear factor I/A0.224
Ccl20chemokine (C-C motif) ligand 200.222
Batf3basic leucine zipper transcription factor, ATF-like 30.214
FynFYN oncogene related to SRC, FGR, YES0.209
Nek9NIMA (never in mitosis gene a)- related kinase 90.204
Rgs1regulator of G-protein signaling 10.201
Hspb1heat shock protein 10.200
Cugbp2CUG triplet repeat, RNA binding protein 20.195
Erbb4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.194
Phox2apaired-like homeobox 2a0.193
Cxcl10chemokine (C-X-C motif) ligand 100.190
Ddr1discoidin domain receptor tyrosine kinase 10.188
Il6interleukin 60.187
Bdkrb2bradykinin receptor B20.186
Ptmaprothymosin alpha0.182
WaslWiskott-Aldrich syndrome-like0.179
Map2microtubule-associated protein 20.178
Ifnb1interferon beta 1, fibroblast0.175
Hoxa1homeo box A10.174
UncxUNC homeobox0.170
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.168
C3complement component 30.167
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.164
Ncam1neural cell adhesion molecule 10.164
Neurod2neurogenic differentiation 20.164
Camk2acalcium/calmodulin-dependent protein kinase II alpha0.164
Tnftumor necrosis factor (TNF superfamily, member 2)0.163
Homer3homer homolog 3 (Drosophila)0.160
Sema6dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D0.160
Lgals3lectin, galactoside-binding, soluble, 30.157
C5ar1complement component 5a receptor 10.157
Inainternexin neuronal intermediate filament protein, alpha0.156
Gcgrglucagon receptor0.154
Cd8aCD8a molecule0.153
Nefmneurofilament, medium polypeptide0.153
Nfibnuclear factor I/B0.152
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.151
Metmet proto-oncogene0.150
Prdx2peroxiredoxin 20.147
Epb4.1l2erythrocyte membrane protein band 4.1-like 20.147
Cd4Cd4 molecule0.147
Pipprolactin induced protein0.145
Lphn2latrophilin 20.145
Shc2SHC (Src homology 2 domain containing) transforming protein 20.145
Fgf18fibroblast growth factor 180.144
Maptmicrotubule-associated protein tau0.143
Ankrd1ankyrin repeat domain 1 (cardiac muscle)0.136
Cd247Cd247 molecule0.136
Slit3slit homolog 3 (Drosophila)0.136
Slc1a1solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 10.135
GraspGRP1 (general receptor for phosphoinositides 1)-associated scaffold protein0.134
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.134
Epha7Eph receptor A70.133
Cxxc4CXXC finger 40.132
Med16mediator complex subunit 160.132
Tgfb1transforming growth factor, beta 10.131
Dccdeleted in colorectal carcinoma0.131
Pebp1phosphatidylethanolamine binding protein 10.130
Kcns1potassium voltage-gated channel, delayed-rectifier, subfamily S, member 10.129
Lin7blin-7 homolog b (C. elegans)0.128
Dlg3discs, large homolog 3 (Drosophila)0.128
Unc45bunc-45 homolog B (C. elegans)0.128
P2ry6pyrimidinergic receptor P2Y, G-protein coupled, 60.127
Npr3natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)0.127
Nfixnuclear factor I/X (CCAAT-binding transcription factor)0.127
Calcrlcalcitonin receptor-like0.126
Sncbsynuclein, beta0.125
Ets1v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)0.125
Cyp11b3cytochrome P450, family 11, subfamily b, polypeptide 30.124
DbpD site of albumin promoter (albumin D-box) binding protein0.124
Spock2sparc/osteonectin, cwcv and kazal-like domains proteoglycan 20.122
Arpc1bactin related protein 2/3 complex, subunit 1B0.122
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism