The network for 'blood vessel endothelial cell migration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

blood vessel endothelial cell migration

The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis.

NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
kdrlkinase insert domain receptor like0.971
notch3notch homolog 30.864
itgb1b.2integrin, beta 1b.20.706
vegfcvascular endothelial growth factor c0.676
dll4delta-like 4 (Drosophila)0.597
plcg1phospholipase C, gamma 10.482
pak2ap21 (CDKN1A)-activated kinase 2a0.419
kdrkinase insert domain receptor (a type III receptor tyrosine kinase)0.406
tal1T-cell acute lymphocytic leukemia 10.290
itgb1aintegrin, beta 1a0.249
efnb2aephrin B2a0.224
cdh5cadherin 50.215
jag2jagged 20.212
vegfaavascular endothelial growth factor Aa0.208
ntrk3bneurotrophic tyrosine kinase, receptor, type 3b0.178
aox3aldehyde oxidase 30.174
pax7bpaired box gene 7b0.172
cav1caveolin 10.172
trpm7transient receptor potential cation channel, subfamily M, member 70.168
ptgs1prostaglandin-endoperoxide synthase 10.157
cdh23cadherin-like 230.157
lpar1lysophosphatidic acid receptor 10.146
csf1racolony stimulating factor 1 receptor, a0.140
calcrlacalcitonin receptor-like a0.138
itga5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.132
tbx2bT-box 2b0.127
epha4aeph receptor A4a0.122
cxcr4bchemokine (C-X-C motif), receptor 4b0.119
mmp2matrix metalloproteinase 20.116
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.114
hsp47heat shock protein 470.114
ptch2patched 20.112
nrp2aneuropilin 2a0.109
itgb1bintegrin, beta 1b0.109
smad9MAD homolog 9 (Drosophila)0.106
ntn4netrin 40.096
myod1myogenic differentiation 10.093
mitfamicrophthalmia-associated transcription factor a0.092
plxnd1plexin D10.091
acta2actin, alpha 2, smooth muscle, aorta0.089
hdac4histone deacetylase 40.088
LOC100003514protein kinase C alpha type-like0.085
lef1lymphocyte enhancer binding factor 10.083
cxcr4achemokine (C-X-C motif) receptor 4a0.083
ptprfprotein tyrosine phosphatase, receptor type, F0.082
sdc2syndecan 20.079
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.076
nrp1aneuropilin 1a0.074
myh11amyosin, heavy polypeptide 11, smooth muscle a0.073
ikzf5IKAROS family zinc finger 50.073
ptprkprotein tyrosine phosphatase, receptor type, K0.072
spry4sprouty (Drosophila) homolog 40.068
dsc2ldesmocollin 2 like0.068
slc16a3solute carrier family 16 (monocarboxylic acid transporters), member 30.066
ppargperoxisome proliferator activated receptor gamma0.066
itgb3bintegrin beta 3b0.066
dusp5dual specificity phosphatase 50.065
lppLIM domain containing preferred translocation partner in lipoma0.064
fstl1bfollistatin-like 1b0.063
csrp1acysteine and glycine-rich protein 1a0.063
ntn1anetrin 1a0.059
pcsk5aproprotein convertase subtilisin/kexin type 5a0.059
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.058
sardhsarcosine dehydrogenase0.057
etv2ets variant gene 20.056
pdgfrb2platelet derived growth factor receptor beta 20.056
pax8paired box gene 80.055
emx3empty spiracles homeobox 30.055
antxr1anthrax toxin receptor 10.054
ptprcprotein tyrosine phosphatase, receptor type, C0.054
ascl1aachaete-scute complex-like 1a (Drosophila)0.052
ccm2cerebral cavernous malformation 20.052
mcambmelanoma cell adhesion molecule b0.051
alcambactivated leukocyte cell adhesion molecule b0.050
sgk1serum/glucocorticoid regulated kinase 10.049
ywhaityrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide0.048
rfx2regulatory factor X, 2 (influences HLA class II expression)0.047
pcsk5bproprotein convertase subtilisin/kexin type 5b0.045
itgavintegrin, alpha V0.045
crb2acrumbs homolog 2a0.044
smad1MAD homolog 1 (Drosophila)0.044
mpllmyeloproliferative leukemia virus oncogene, like0.043
ptrfbpolymerase I and transcript release factor b0.042
unc5bunc-5 homolog B (C. elegans)0.042
kitlgakit ligand a0.042
guca1cguanylate cyclase activator 1C0.041
fabp11afatty acid binding protein 11a0.041
furinbfurin (paired basic amino acid cleaving enzyme) b0.041
pax7apaired box gene 7a0.040
tll1tolloid-like 10.039
ryr3ryanodine receptor 30.039
wt1bwilms tumor 1b0.039
gli2bGLI-Kruppel family member GLI2b0.038
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
FN1fibronectin 11.000
JAG1jagged 10.994
FGFR2fibroblast growth factor receptor 20.992
FLNAfilamin A, alpha0.990
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.985
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.980
YAP1Yes-associated protein 10.978
TEKTEK tyrosine kinase, endothelial0.972
VEGFAvascular endothelial growth factor A0.945
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.941
TGFB1transforming growth factor, beta 10.936
BMP2bone morphogenetic protein 20.924
NCF1neutrophil cytosolic factor 10.922
NOTCH1notch 10.915
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.878
FKBP1AFK506 binding protein 1A, 12kDa0.876
ZFP36zinc finger protein 36, C3H type, homolog (mouse)0.874
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.868
JUNjun proto-oncogene0.863
NRP1neuropilin 10.841
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.837
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.834
NOTCH3notch 30.818
KLF4Kruppel-like factor 4 (gut)0.809
BAG3BCL2-associated athanogene 30.799
FOSBFBJ murine osteosarcoma viral oncogene homolog B0.794
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.724
FGF1fibroblast growth factor 1 (acidic)0.672
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.660
NR4A1nuclear receptor subfamily 4, group A, member 10.651
FOSFBJ murine osteosarcoma viral oncogene homolog0.642
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.640
EGR1early growth response 10.636
MAP3K3mitogen-activated protein kinase kinase kinase 30.628
ACTBactin, beta0.620
SMAD7SMAD family member 70.618
PDLIM7PDZ and LIM domain 7 (enigma)0.611
EGR3early growth response 30.582
MEF2Cmyocyte enhancer factor 2C0.573
CYR61cysteine-rich, angiogenic inducer, 610.554
FGFR1fibroblast growth factor receptor 10.528
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.505
AMOTL1angiomotin like 10.484
LCKlymphocyte-specific protein tyrosine kinase0.457
NOXA1NADPH oxidase activator 10.414
GNAI2guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 20.413
MYH9myosin, heavy chain 9, non-muscle0.413
CRYABcrystallin, alpha B0.393
NR4A2nuclear receptor subfamily 4, group A, member 20.374
HDAC7histone deacetylase 70.349
NEDD4neural precursor cell expressed, developmentally down-regulated 40.342
EPHA7EPH receptor A70.337
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.316
THBS1thrombospondin 10.307
ACTN4actinin, alpha 40.300
ILKintegrin-linked kinase0.300
GRB7growth factor receptor-bound protein 70.295
FYNFYN oncogene related to SRC, FGR, YES0.291
PRKCAprotein kinase C, alpha0.288
FBLN1fibulin 10.281
PSEN2presenilin 2 (Alzheimer disease 4)0.262
SKILSKI-like oncogene0.261
POU3F2POU class 3 homeobox 20.235
TGFBR1transforming growth factor, beta receptor 10.230
HSPG2heparan sulfate proteoglycan 20.213
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.212
ACTN1actinin, alpha 10.198
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.193
PRKCDprotein kinase C, delta0.190
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.189
PTPRBprotein tyrosine phosphatase, receptor type, B0.188
LATlinker for activation of T cells0.188
EGR2early growth response 20.182
PTPN6protein tyrosine phosphatase, non-receptor type 60.180
FGAfibrinogen alpha chain0.179
TLN1talin 10.175
IER2immediate early response 20.174
PAX3paired box 30.171
LMNAlamin A/C0.169
POU5F1POU class 5 homeobox 10.168
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.163
TPM4tropomyosin 40.161
PLCG1phospholipase C, gamma 10.155
ANXA1annexin A10.149
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.148
JAG2jagged 20.147
CD3ECD3e molecule, epsilon (CD3-TCR complex)0.147
JUNBjun B proto-oncogene0.146
DUSP1dual specificity phosphatase 10.146
TIE1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.145
FHL2four and a half LIM domains 20.145
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Efnb2ephrin B20.997
Notch1Notch gene homolog 1 (Drosophila)0.966
Itgb1integrin beta 1 (fibronectin receptor beta)0.945
Nos3nitric oxide synthase 3, endothelial cell0.941
Jag1jagged 10.918
Sema3fsema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F0.916
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.903
Psen1presenilin 10.896
Vegfavascular endothelial growth factor A0.830
Apoeapolipoprotein E0.741
Kdrkinase insert domain protein receptor0.738
Ephb2Eph receptor B20.698
Cyr61cysteine rich protein 610.679
Tgfb2transforming growth factor, beta 20.640
Flt4FMS-like tyrosine kinase 40.627
Ptpn11protein tyrosine phosphatase, non-receptor type 110.607
Hey2hairy/enhancer-of-split related with YRPW motif 20.600
Gata4GATA binding protein 40.580
Gli3GLI-Kruppel family member GLI30.535
Fgfr1fibroblast growth factor receptor 10.524
Epha4Eph receptor A40.504
Flt1FMS-like tyrosine kinase 10.495
Meox2mesenchyme homeobox 20.459
Csf1colony stimulating factor 1 (macrophage)0.459
Notch2Notch gene homolog 2 (Drosophila)0.435
Ptk2PTK2 protein tyrosine kinase 20.409
Ntf3neurotrophin 30.407
Plxnd1plexin D10.403
Rb1retinoblastoma 10.374
Fgfr2fibroblast growth factor receptor 20.373
Slit2slit homolog 2 (Drosophila)0.343
Efna1ephrin A10.341
Dll1delta-like 1 (Drosophila)0.304
Smad3MAD homolog 3 (Drosophila)0.298
Adam19a disintegrin and metallopeptidase domain 19 (meltrin beta)0.285
Slit3slit homolog 3 (Drosophila)0.283
Efnb1ephrin B10.277
Pax1paired box gene 10.260
Dock1dedicator of cytokinesis 10.235
Tcte3t-complex-associated testis expressed 30.231
Mef2dmyocyte enhancer factor 2D0.221
Itga5integrin alpha 5 (fibronectin receptor alpha)0.213
Hif1ahypoxia inducible factor 1, alpha subunit0.209
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.194
Gata6GATA binding protein 60.189
Gli2GLI-Kruppel family member GLI20.184
Ephb3Eph receptor B30.183
Sox7SRY-box containing gene 70.169
Rag1recombination activating gene 10.169
Itga3integrin alpha 30.164
Cdh5cadherin 50.152
Foxf2forkhead box F20.148
Lrp1low density lipoprotein receptor-related protein 10.146
Adamts1a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10.141
Foxg1forkhead box G10.140
Lmnalamin A0.139
Gdnfglial cell line derived neurotrophic factor0.136
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.128
Klf2Kruppel-like factor 2 (lung)0.127
Pax3paired box gene 30.127
Vangl2vang-like 2 (van gogh, Drosophila)0.126
Actn1actinin, alpha 10.121
Plcg1phospholipase C, gamma 10.119
Itgb3integrin beta 30.116
Col4a2collagen, type IV, alpha 20.115
Bcl2B-cell leukemia/lymphoma 20.115
Wwtr1WW domain containing transcription regulator 10.114
HlxH2.0-like homeobox0.111
Egfrepidermal growth factor receptor0.109
Cdkn2acyclin-dependent kinase inhibitor 2A0.106
Prl7d1prolactin family 7, subfamily d, member 10.104
Emp2epithelial membrane protein 20.104
Tead1TEA domain family member 10.103
Tgfb1transforming growth factor, beta 10.100
Mmp15matrix metallopeptidase 150.099
Ctnnb1catenin (cadherin associated protein), beta 10.097
Ptk7PTK7 protein tyrosine kinase 70.095
Prl8a6prolactin family 8, subfamily a, member 60.092
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.092
Jupjunction plakoglobin0.091
Smad6MAD homolog 6 (Drosophila)0.090
Trp63transformation related protein 630.090
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.089
Myo1cmyosin IC0.088
Emx1empty spiracles homolog 1 (Drosophila)0.087
Tgfb1i1transforming growth factor beta 1 induced transcript 10.085
Cdc42ep1CDC42 effector protein (Rho GTPase binding) 10.084
Snai1snail homolog 1 (Drosophila)0.083
Robo2roundabout homolog 2 (Drosophila)0.082
Nkx2-1NK2 homeobox 10.082
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.082
Eya1eyes absent 1 homolog (Drosophila)0.079
Prl3d1prolactin family 3, subfamily d, member 10.077
Chd7chromodomain helicase DNA binding protein 70.074
F12coagulation factor XII (Hageman factor)0.073
Zfpm2zinc finger protein, multitype 20.073
Notch3Notch gene homolog 3 (Drosophila)0.072
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism