The network for 'regulation of cell death' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of cell death

Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.

NameDescriptionProbabilityFunc Analog Organism
egl-18Protein EGL-180.679
par-5Protein PAR-50.437
eya-1Protein EYA-10.313
ceh-20Protein CEH-200.289
F36D4.5Protein F36D4.50.247
egl-46Protein EGL-460.212
cam-1Protein CAM-10.192
lmn-1Protein LMN-10.185
sem-5Protein SEM-50.181
hcp-3Protein HCP-30.149
mab-31Protein MAB-310.145
hsp-1Protein HSP-10.142
nhr-67Protein NHR-670.126
bar-1Protein BAR-10.125
drp-1Protein DRP-10.123
hum-6Protein HUM-60.119
unc-70Protein UNC-700.119
inx-13Protein INX-130.110
unc-9Protein UNC-90.107
pha-4Protein PHA-40.105
ftt-2Protein FTT-20.105
F36A2.13Protein F36A2.130.100
hum-5Protein HUM-50.099
rlbp-1Protein RLBP-10.099
mel-11Protein MEL-110.095
K10D6.4Protein K10D6.40.095
C28H8.3Protein C28H8.30.093
sax-7Protein SAX-70.093
fkh-2Protein FKH-20.092
rnr-2Protein RNR-20.092
mat-3Protein MAT-30.090
soc-2Protein SOC-20.085
vab-3Protein VAB-30.085
trim-9Protein TRIM-90.084
CELE_Y41E3.7Protein Y41E3.70.078
erm-1Protein ERM-10.077
pdfr-1Protein PDFR-10.076
inx-3Protein INX-30.075
F39B2.1Protein F39B2.10.075
xbp-1Protein XBP-10.074
eef-1A.1Protein EEF-1A.10.073
unc-52Protein UNC-520.073
ceh-44Protein CEH-440.070
vhp-1Protein VHP-10.069
lst-4Protein LST-40.069
sma-6Protein SMA-60.069
lin-17Protein LIN-170.069
exc-5Protein EXC-50.068
egl-30Protein EGL-300.067
F59E12.9Protein F59E12.90.065
unc-86Protein UNC-860.064
sym-4Protein SYM-40.064
unc-73Protein UNC-730.064
let-756Protein LET-7560.064
syg-1Protein SYG-10.063
scd-1Protein SCD-10.063
zyg-9Protein ZYG-90.063
CELE_F14E5.2Protein F14E5.20.062
ttx-1Protein TTX-10.061
rme-4Protein RME-40.060
age-1Protein AGE-10.060
sos-1Protein SOS-10.060
lig-4Protein LIG-40.059
unc-43Protein UNC-430.058
gex-3Protein GEX-30.058
nhr-34Protein NHR-340.058
ets-4Protein ETS-40.058
F44E7.4Protein F44E7.40.057
tag-260Protein TAG-2600.056
cey-1Protein CEY-10.055
CELE_Y52B11A.10Protein Y52B11A.100.054
atp-2Protein ATP-20.054
skp-1Protein SKP-10.054
zip-7Protein ZIP-70.054
clic-1Protein CLIC-10.053
T28C6.7Protein T28C6.70.053
gpb-2Protein GPB-20.053
pal-1Protein PAL-10.053
mef-2Protein MEF-20.053
tra-3Protein TRA-30.052
nhr-45Protein NHR-450.052
egl-27Protein EGL-270.051
T05E8.3Protein T05E8.30.051
T23F4.2Protein T23F4.20.050
dcr-1Protein DCR-10.050
amph-1Protein AMPH-10.050
egl-5Protein EGL-50.050
rgs-7Protein RGS-70.050
F31C3.3Protein F31C3.30.050
hpo-34Protein HPO-340.049
eat-6Protein EAT-60.049
ifg-1Protein IFG-10.048
tbx-8Protein TBX-80.048
act-5Protein ACT-50.048
mig-5Protein MIG-50.048
egl-13Protein EGL-130.048
aap-1Protein AAP-10.047
R90.1Protein R90.10.047
vav-1Protein VAV-10.047
lag-1Protein LAG-10.047
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
fgfr1afibroblast growth factor receptor 1a0.943
trpm7transient receptor potential cation channel, subfamily M, member 70.902
gata3GATA-binding protein 30.891
gcm2glial cells missing homolog 2 (Drosophila)0.842
fgf3fibroblast growth factor 30.836
pitx3paired-like homeodomain transcription factor 30.744
cmybtranscription factor cmyb0.677
shhasonic hedgehog a0.676
baxabcl2-associated X protein, a0.631
tp53tumor protein p530.617
bdnfbrain-derived neurotrophic factor0.611
fgf8afibroblast growth factor 8 a0.610
tbx1T-box 10.594
hif1abhypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b0.557
efnb2aephrin B2a0.542
rargaretinoic acid receptor gamma a0.541
evx1even-skipped homeobox 10.534
lmx1b.1LIM homeobox transcription factor 1, beta 10.533
chdchordin0.511
tbx20T-box 200.506
runx2brunt-related transcription factor 2b0.506
hey1hairy/enhancer-of-split related with YRPW motif 10.496
xbp1X-box binding protein 10.494
sfrp5secreted frizzled-related protein 50.489
flt4fms-related tyrosine kinase 40.488
ef1aelongation factor 1-alpha0.476
ndr2nodal-related 20.460
arnt2aryl hydrocarbon receptor nuclear translocator 20.447
kitakit receptor a0.439
plcg1phospholipase C, gamma 10.436
pax2apaired box gene 2a0.420
atp6v1baATPase, H+ transporting, lysosomal, V1 subunit B, member a0.410
bbc3BCL2 binding component 30.397
tnfrsfatumor necrosis factor receptor superfamily, member a0.393
smc3structural maintenance of chromosomes 30.393
bmp2bbone morphogenetic protein 2b0.390
pcdh17protocadherin 170.386
bactin1bactin10.384
ptf1apancreas specific transcription factor, 1a0.382
ascl1aachaete-scute complex-like 1a (Drosophila)0.379
dusp6dual specificity phosphatase 60.374
hoxb1bhomeo box B1b0.373
dkk1bdickkopf 1b0.367
nadl1.2neural adhesion molecule L1.20.360
fn1fibronectin 10.359
col14a1collagen, type XIV, alpha 10.353
bcl2l1bcl2-like 10.342
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.336
tyrtyrosinase0.334
bocbrother of CDO0.321
cav1caveolin 10.315
metmet proto-oncogene (hepatocyte growth factor receptor)0.313
mcl1amyeloid cell leukemia sequence 1a0.308
gli1GLI-Kruppel family member 10.300
jag1ajagged 1a0.298
ptpraprotein tyrosine phosphatase, receptor type, A0.296
piwil2piwi-like 2 (Drosophila)0.295
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.294
nrg2aneuregulin 2a0.291
atp6v0caATPase, H+ transporting, lysosomal, V0 subunit c, a0.288
rag1recombination activating gene 10.288
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.287
thtyrosine hydroxylase0.285
fgfr4fibroblast growth factor receptor 40.285
cdh1cadherin 1, epithelial0.280
spry4sprouty (Drosophila) homolog 40.277
tp63tumor protein p630.274
bnc2basonuclin 20.273
gata4GATA-binding protein 40.272
csnk1dacasein kinase 1, delta a0.272
rorcaRAR-related orphan receptor C a0.270
nadl1.1neural adhesion molecule L1.10.269
rbb4lretinoblastoma binding protein 4, like0.269
cadcarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase0.267
rasl11bRAS-like, family 11, member B0.267
alcamaactivated leukocyte cell adhesion molecule a0.266
ptgs2aprostaglandin-endoperoxide synthase 2a0.264
notch1anotch homolog 1a0.263
col12a1collagen, type XII, alpha 10.259
hspa5heat shock protein 50.256
six3bsine oculis homeobox homolog 3b0.253
foxp2forkhead box P20.248
myod1myogenic differentiation 10.247
tbx16T-box gene 160.247
wnt4awingless-type MMTV integration site family, member 4a0.246
klf4Kruppel-like factor 40.246
esr2aestrogen receptor 2a0.243
sulf2lsulfatase 2, like0.242
otpaorthopedia homolog a0.240
wnt11rwingless-type MMTV integration site family, member 11, related0.238
barhl1.2BarH-like 1.20.234
stmn1bstathmin 1b0.229
cdh23cadherin-like 230.226
cct6achaperonin containing TCP1, subunit 6A (zeta 1)0.226
tshbthyroid stimulating hormone, beta subunit0.225
epb41l5erythrocyte membrane protein band 4.1 like 50.225
sema3aasemaphorin 3aa0.222
tnctenascin C0.217
notch2notch homolog 20.217
badBCL2-antagonist of cell death0.216
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
nejnejire0.999
slmbsupernumerary limbs0.993
wgwingless0.990
tkvthickveins0.989
EcREcdysone receptor0.986
Akt1CG4006 gene product from transcript CG4006-RA0.977
dmdiminutive0.973
MadMothers against dpp0.959
Ras85DRas oncogene at 85D0.952
cicubitus interruptus0.936
Atg1Autophagy-specific gene 10.935
kaykayak0.935
rprreaper0.914
lealeak0.837
hephemipterous0.834
shishibire0.833
RbfRetinoblastoma-family protein0.809
Pi3K92ECG4141 gene product from transcript CG4141-RB0.807
CG11347CG11347 gene product from transcript CG11347-RE0.791
EgfrEpidermal growth factor receptor0.784
kibrakibra ortholog0.777
chicoCG5686 gene product from transcript CG5686-RB0.774
panpangolin0.770
S6kRPS6-p70-protein kinase0.758
Dcp-1Death caspase-10.727
emsempty spiracles0.717
drkdownstream of receptor kinase0.693
twstwins0.684
hthhomothorax0.676
foxoforkhead box, sub-group O0.672
CtBPC-terminal Binding Protein0.641
Gyc76CGuanylyl cyclase at 76C0.611
mrnmarionette0.603
rapretina aberrant in pattern0.601
giggigas0.599
Trf2TATA box binding protein-related factor 20.596
PtenCG5671 gene product from transcript CG5671-RB0.592
p53CG33336 gene product from transcript CG33336-RB0.590
cutletCG33122 gene product from transcript CG33122-RA0.590
TorTarget of rapamycin0.585
CadNCadherin-N0.581
PakPAK-kinase0.575
Src42ASrc oncogene at 42A0.566
dadaughterless0.564
pAbppolyA-binding protein0.564
trptransient receptor potential0.559
UbxUltrabithorax0.559
sdscalloped0.557
Atx2Ataxin-20.556
kiskismet0.553
Top2Topoisomerase 20.549
brmbrahma0.547
Aos1CG12276 gene product from transcript CG12276-RA0.542
CG9772CG9772 gene product from transcript CG9772-RB0.538
WWrinkled0.534
belbelle0.532
agoarchipelago0.531
ththread0.524
crolcrooked legs0.523
Fmr1CG6203 gene product from transcript CG6203-RC0.522
miltmilton0.520
Mekk1CG7717 gene product from transcript CG7717-RB0.514
Gp150CG5820 gene product from transcript CG5820-RA0.505
flwflapwing0.504
InRInsulin-like receptor0.503
Hnf4Hepatocyte nuclear factor 40.501
shnschnurri0.500
DrefDNA replication-related element factor0.499
Hel25EHelicase at 25E0.494
edechinoid0.486
DadDaughters against dpp0.486
elavembryonic lethal abnormal vision0.482
mpmultiplexin0.473
dshdishevelled0.471
DAAMDishevelled Associated Activator of Morphogenesis0.459
armarmadillo0.459
eIF-4EEukaryotic initiation factor 4E0.451
cazcabeza0.447
jarjaguar0.442
nkdnaked cuticle0.441
SoxNSoxNeuro0.440
Trxr-1Thioredoxin reductase-10.440
zipzipper0.427
Arr2Arrestin 20.425
msnmisshapen0.424
trpltrp-like0.424
trioCG18214 gene product from transcript CG18214-RA0.422
exexpanded0.421
TBPHCG10327 gene product from transcript CG10327-RC0.421
drlderailed0.419
Nop60BNucleolar protein at 60B0.418
Su(H)Suppressor of Hairless0.413
FsFollistatin0.408
AntpAntennapedia0.404
Dsp1Dorsal switch protein 10.403
witwishful thinking0.402
Trx-2thioredoxin-20.398
beta-Specbeta Spectrin0.397
alpha-AdaptinCG4260 gene product from transcript CG4260-RA0.395
wtswarts0.393
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
HYP2Hyp2p0.011
SLT2Slt2p0.011