The network for 'pronuclear migration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

pronuclear migration

The directed movement of the male and female pronuclei towards each other prior to their fusion.

NameDescriptionProbabilityFunc Analog Organism
tbb-1Protein TBB-10.968
rnr-1Protein RNR-10.915
tba-1Protein TBA-10.901
pbs-2Protein PBS-20.899
rpt-3Protein RPT-30.863
gpr-1Protein GPR-10.827
rpn-1Protein RPN-10.823
pbs-5Protein PBS-50.808
spdl-1Protein SPDL-10.765
rpa-2Protein RPA-20.755
CELE_C38D4.4Protein C38D4.40.748
ZK418.9Protein ZK418.90.726
rpn-12Protein RPN-120.724
rpn-5Protein RPN-50.722
rpt-5Protein RPT-50.637
dli-1Protein DLI-10.625
pas-1Protein PAS-10.614
rpn-7Protein RPN-70.612
cyk-4Protein CYK-40.559
hcp-1Protein HCP-10.552
tba-2Protein TBA-20.540
mec-7Protein MEC-70.530
smo-1Protein SMO-10.518
egl-45Protein EGL-450.514
his-64Protein HIS-640.513
gars-1Protein GARS-10.509
pas-4Protein PAS-40.502
rpn-10Protein RPN-100.449
pfd-2Protein PFD-20.447
rpb-12Protein RPB-120.446
CELE_Y39E4B.5Protein Y39E4B.50.425
his-31Protein HIS-310.422
glh-4Protein GLH-40.414
gpd-4Protein GPD-40.405
his-46Protein HIS-460.396
his-45Protein HIS-450.385
pcn-1Protein PCN-10.380
his-47Protein HIS-470.354
pbs-1Protein PBS-10.350
daf-21Protein DAF-210.345
rpn-2Protein RPN-20.342
his-48Protein HIS-480.342
T28D9.4Protein T28D9.40.328
fars-1Protein FARS-10.327
lin-35Protein LIN-350.327
lmn-1Protein LMN-10.296
rars-1Protein RARS-10.296
puf-6Protein PUF-60.293
his-61Protein HIS-610.293
cmd-1Protein CMD-10.288
eif-3.DProtein EIF-3.D0.288
nars-1Protein NARS-10.280
his-30Protein HIS-300.280
mep-1Protein MEP-10.279
dlc-1Protein DLC-10.278
csr-1Protein CSR-10.275
cpg-2Protein CPG-20.274
pas-6Protein PAS-60.265
let-418Protein LET-4180.260
T11G6.8Protein T11G6.80.257
his-62Protein HIS-620.254
cey-2Protein CEY-20.253
T19H12.2Protein T19H12.20.253
let-754Protein LET-7540.246
rpn-9Protein RPN-90.246
cdk-1Protein CDK-10.245
cyb-2.1Protein CYB-2.10.243
oma-1Protein OMA-10.240
his-35Protein HIS-350.233
fzy-1Protein FZY-10.230
cra-1Protein CRA-10.229
CELE_C39E9.12Protein C39E9.120.229
Y55B1AL.2Protein Y55B1AL.20.229
pfd-3Protein PFD-30.221
C01G8.1Protein C01G8.10.214
gpr-2Protein GPR-20.214
W08E12.7Protein W08E12.70.212
klp-16Protein KLP-160.210
CELE_Y14H12B.2Protein Y14H12B.20.207
mcm-7Protein MCM-70.204
F48E8.6Protein F48E8.60.201
mcm-3Protein MCM-30.199
usp-14Protein USP-140.197
pept-1Protein PEPT-10.197
tbb-2Protein TBB-20.195
mex-6Protein MEX-60.183
lin-5Protein LIN-50.182
knl-3Protein KNL-30.182
eat-6Protein EAT-60.180
bag-1Protein BAG-10.178
brc-1Protein BRC-10.176
hsp-1Protein HSP-10.175
sqv-4Protein SQV-40.174
M88.5Protein M88.50.172
kars-1Protein KARS-10.171
cdtl-7Protein CDTL-70.167
mars-1Protein MARS-10.163
rpt-1Protein RPT-10.162
mlc-5Protein MLC-50.161
cif-1Protein CIF-10.160
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
ywhaqbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b0.989
ywhabatyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a0.954
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.927
ywhae1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 10.922
ywhabbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b0.882
gro1groucho 10.832
gnb1aguanine nucleotide binding protein (G protein), beta polypeptide 1a0.755
dynlrb1dynein, light chain, roadblock-type 10.739
pfn2lprofilin 2 like0.675
ywhaqatyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a0.672
ywhabltyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like0.651
fkbp1aaFK506 binding protein 1Aa0.600
pafah1b1aplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a0.571
calm3bcalmodulin 3b (phosphorylase kinase, delta)0.543
ccnb1cyclin B10.539
lsm4LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)0.534
cdc42cell division cycle 420.519
ephb4beph receptor B4b0.495
gro2groucho 20.491
psmc1aproteasome (prosome, macropain) 26S subunit, ATPase, 1a0.477
psmb2proteasome (prosome, macropain) subunit, beta type, 20.471
sass6spindle assembly 6 homolog (C. elegans)0.465
atp1b3bATPase, Na+/K+ transporting, beta 3b polypeptide0.446
lsm7LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)0.431
dynlt3dynein, light chain, Tctex-type 30.391
rabifRAB interacting factor0.378
actr1ARP1 actin-related protein 1, centractin (yeast)0.369
snrpesmall nuclear ribonucleoprotein polypeptide E0.364
dpysl5adihydropyrimidinase-like 5a0.363
psmb4proteasome (prosome, macropain) subunit, beta type, 40.331
uchl1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)0.287
lsm6LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)0.281
aurkbaurora kinase B0.268
tbx1T-box 10.265
atp6v0caATPase, H+ transporting, lysosomal, V0 subunit c, a0.254
ube2v2ubiquitin-conjugating enzyme E2 variant 20.246
pou5f1POU domain, class 5, transcription factor 10.245
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.239
ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.237
rae1RAE1 RNA export 1 homolog (S. pombe)0.235
rbpjarecombination signal binding protein for immunoglobulin kappa J region a0.235
psmb3proteasome (prosome, macropain) subunit, beta type, 30.223
ppp2r1bprotein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform0.220
cdc26cell division cycle 26 homolog0.209
pobpartial optokinetic response b0.209
mobkl3MOB1, Mps One Binder kinase activator-like 3 (yeast)0.196
dctn2dynactin 2 (p50)0.195
pgam1bphosphoglycerate mutase 1b0.183
psmc6proteasome (prosome, macropain) 26S subunit, ATPase, 60.177
gng7guanine nucleotide binding protein (G protein), gamma 70.177
ift88intraflagellar transport 88 homolog0.175
eny2enhancer of yellow 2 homolog (Drosophila)0.174
anp32bacidic (leucine-rich) nuclear phosphoprotein 32 family, member B0.173
cops8COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)0.171
psmd4bproteasome (prosome, macropain) 26S subunit, non-ATPase, 4b0.169
psmd4aproteasome (prosome, macropain) 26S subunit, non-ATPase, 4a0.162
ptpraprotein tyrosine phosphatase, receptor type, A0.161
snrpd3lsmall nuclear ribonucleoprotein D3 polypeptide, like0.153
dynll1dynein, light chain, LC8-type 10.145
ccna2cyclin A20.143
ywhaityrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide0.141
dctn1adynactin 1a0.135
ttc35tetratricopeptide repeat domain 350.130
pfdn6prefoldin subunit 60.127
tbcatubulin cofactor a0.126
skp1S-phase kinase-associated protein 10.126
rhoabras homolog gene family, member Ab0.123
ppialpeptidylprolyl isomerase A, like0.121
psmc3proteasome (prosome, macropain) 26S subunit, ATPase, 30.121
vps35vacuolar protein sorting 35 (yeast)0.118
atp1b2aATPase, Na+/K+ transporting, beta 2a polypeptide0.117
psma8proteasome (prosome, macropain) subunit, alpha type, 80.115
sf3b5splicing factor 3b, subunit 50.114
gng5guanine nucleotide binding protein (G protein), gamma 50.112
arpc3actin related protein 2/3 complex, subunit 30.107
fancd2Fanconi anemia, complementation group D20.104
ck2bcasein kinase 2 beta0.104
gle1GLE1 RNA export mediator homolog (yeast)0.100
kif23kinesin family member 230.100
polr2cpolymerase (RNA) II (DNA directed) polypeptide C0.099
pppde1PPPDE peptidase domain containing 10.099
wrbtryptophan rich basic protein0.098
lama1laminin, alpha 10.098
ptpn11aprotein tyrosine phosphatase, non-receptor type 11, a0.097
znf711zinc finger protein 7110.096
arf2ADP-ribosylation factor 20.096
snx12sorting nexin 120.096
erhenhancer of rudimentary homolog (Drosophila)0.095
hsbp1heat shock factor binding protein 10.095
cops3COP9 constitutive photomorphogenic homolog subunit 30.092
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
l(3)01239lethal (3) 012390.949
Fs(2)KetFemale sterile (2) Ketel0.935
ncdnon-claret disjunctional0.893
CycBCyclin B0.893
sanseparation anxiety0.687
Arp66BActin-related protein 66B0.600
JIL-1CG6297 gene product from transcript CG6297-RA0.596
sqhspaghetti squash0.594
Cks30ACyclin-dependent kinase subunit 30A0.576
Klp61FKinesin-like protein at 61F0.544
BubR1Bub1-related kinase0.474
Sop2Suppressor of profilin 20.414
14-3-3epsilonCG31196 gene product from transcript CG31196-RA0.384
gammaTub37Cgamma-Tubulin at 37C0.380
cpacapping protein alpha0.372
Arp87CActin-related protein 87C0.305
eastenhanced adult sensory threshold0.295
spn-Espindle E0.288
Klp3AKinesin-like protein at 3A0.273
Dhc64CDynein heavy chain 64C0.262
DlicDynein light intermediate chain0.243
poloCG12306 gene product from transcript CG12306-RA0.227
G-ialpha65AG protein alphai subunit 65A0.199
aspabnormal spindle0.196
CG7770CG7770 gene product from transcript CG7770-RA0.194
lkb1CG9374 gene product from transcript CG9374-RJ0.189
Ggamma1G protein gamma 10.175
dpadisc proliferation abnormal0.173
nodno distributive disjunction0.170
tacctransforming acidic coiled-coil protein0.158
alphaTub67Calpha-Tubulin at 67C0.154
marsCG17064 gene product from transcript CG17064-RB0.152
aPKCatypical protein kinase C0.151
RalaRas-related protein0.144
Cap-GCG34438 gene product from transcript CG34438-RF0.143
Syx13Syntaxin 130.140
Nek2CG17256 gene product from transcript CG17256-RA0.135
Eb1CG3265 gene product from transcript CG3265-RF0.129
Orc2Origin recognition complex subunit 20.126
CG4680CG4680 gene product from transcript CG4680-RA0.121
Mi-2CG8103 gene product from transcript CG8103-RA0.117
Mlc-cMyosin light chain cytoplasmic0.115
me31Bmaternal expression at 31B0.108
ari-2ariadne 20.092
XpdXeroderma pigmentosum D0.082
betaTub56Dbeta-Tubulin at 56D0.082
MybMyb oncogene-like0.077
par-6CG5884 gene product from transcript CG5884-RA0.074
Nipped-BCG17704 gene product from transcript CG17704-RI0.072
CG7048CG7048 gene product from transcript CG7048-RB0.067
mus304mutagen-sensitive 3040.063
Klp10ACG1453 gene product from transcript CG1453-RA0.061
Elongin-CElongin C0.055
Cdc37CG12019 gene product from transcript CG12019-RA0.055
Ard1Arrest defective 10.052
Hr39Hormone receptor-like in 390.050
CG4699CG4699 gene product from transcript CG4699-RJ0.049
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism