The network for 'anterior posterior axon guidance' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

anterior posterior axon guidance

The process in which the migration of an axon growth cone is directed to a specific target site along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.

NameDescriptionProbabilityFunc Analog Organism
cdh-3Protein CDH-30.468
lin-17Protein LIN-170.371
unc-5Protein UNC-50.245
trim-9Protein TRIM-90.239
cwn-1Protein CWN-10.159
chd-7Protein CHD-70.155
plx-2Protein PLX-20.153
ceh-20Protein CEH-200.094
igcm-3Protein IGCM-30.089
fmi-1Protein FMI-10.081
syd-9Protein SYD-90.077
R10E12.2Protein R10E12.20.077
gap-2Protein GAP-20.068
unc-9Protein UNC-90.057
ptp-3Protein PTP-30.056
T02E9.5Protein T02E9.50.056
T24B8.3Protein T24B8.30.054
unc-129Protein UNC-1290.054
ain-1Protein AIN-10.052
cam-1Protein CAM-10.050
ceh-6Protein CEH-60.046
jmjd-3.1Protein JMJD-3.10.046
sdn-1Protein SDN-10.044
kal-1Protein KAL-10.039
unc-41Protein UNC-410.037
unc-6Protein UNC-60.035
psa-3Protein PSA-30.034
F28E10.1Protein F28E10.10.030
rig-6Protein RIG-60.027
cogc-2Protein COGC-20.026
efl-3Protein EFL-30.026
cutl-16Protein CUTL-160.024
ast-1Protein AST-10.024
C43H6.4Protein C43H6.40.024
lin-25Protein LIN-250.023
nlr-1Protein NLR-10.021
kin-32Protein KIN-320.020
tbb-4Protein TBB-40.020
F35D2.3Protein F35D2.30.020
ten-1Protein TEN-10.019
agr-1Protein AGR-10.019
zoo-1Protein ZOO-10.019
lin-12Protein LIN-120.018
hmg-11Protein HMG-110.017
cdh-4Protein CDH-40.016
R02D5.1Protein R02D5.10.016
swan-2Protein SWAN-20.016
ZK54.1Protein ZK54.10.015
F53B3.5Protein F53B3.50.015
C56G2.4Protein C56G2.40.015
CELE_F47G4.4Protein F47G4.40.015
hlh-1Protein HLH-10.015
F11D5.1Protein F11D5.10.015
Y71F9B.9Protein Y71F9B.90.014
F58H1.5Protein F58H1.50.014
C03A3.1Protein C03A3.10.013
pxd-1Protein PXD-10.013
klp-11Protein KLP-110.012
eor-2Protein EOR-20.012
ncam-1Protein NCAM-10.012
sup-17Protein SUP-170.012
nhr-25Protein NHR-250.012
alg-1Protein ALG-10.011
ddr-2Protein DDR-20.011
K05F1.5Protein K05F1.50.011
ceh-32Protein CEH-320.011
hhat-2Protein HHAT-20.010
pqn-55Protein PQN-550.010
T24H10.1Protein T24H10.10.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
lhx2bLIM homeobox 2b1.000
bocbrother of CDO0.998
robo3roundabout homolog 30.990
shhasonic hedgehog a0.922
smosmoothened homolog (Drosophila)0.831
tbx1T-box 10.817
robo2roundabout homolog 20.811
evx1even-skipped homeobox 10.808
tbx2bT-box 2b0.766
ptch2patched 20.755
fgf3fibroblast growth factor 30.639
msxcmuscle segment homeobox C0.635
fgfr3fibroblast growth factor receptor 30.575
slit2slit (Drosophila) homolog 20.535
dladeltaA0.465
dzip1DAZ interacting protein 10.427
slit3slit (Drosophila) homolog 30.406
lef1lymphocyte enhancer binding factor 10.391
pax2apaired box gene 2a0.387
tcf7transcription factor 7 (T-cell specific, HMG-box)0.333
prdm1aPR domain containing 1a, with ZNF domain0.309
twist1atwist1a0.306
wnt3wingless-type MMTV integration site family, member 30.269
foxd3forkhead box D30.232
gli1GLI-Kruppel family member 10.227
hoxa13bhomeo box A13b0.214
znf503zinc finger protein 5030.211
ntn1anetrin 1a0.200
tnctenascin C0.191
ndr2nodal-related 20.188
foxp2forkhead box P20.186
nrp1aneuropilin 1a0.178
irx1airoquois homeobox protein 1, a0.177
sox9aSRY-box containing gene 9a0.174
epha4aeph receptor A4a0.174
cdh2cadherin 2, neuronal0.171
tfap2atranscription factor AP-2 alpha0.171
fzd9bfrizzled homolog 9b0.166
zgc:158603zgc:1586030.164
disp1dispatched homolog 1 (Drosophila)0.163
twist3twist30.160
sema3dsemaphorin 3d0.158
robo1roundabout homolog 10.153
scube2signal peptide, CUB domain, EGF-like 20.133
cdoncell adhesion molecule-related/down-regulated by oncogenes0.133
neurog1neurogenin 10.127
msxdmuscle segment homeobox D0.117
dbx1adeveloping brain homeobox 1a0.114
wnt5bwingless-type MMTV integration site family, member 5b0.112
sec24dSEC24 family, member D (S. cerevisiae)0.112
gli2aGLI-Kruppel family member GLI2a0.111
gli2bGLI-Kruppel family member GLI2b0.109
arxaristaless related homeobox0.103
bmp2bbone morphogenetic protein 2b0.102
ephb4beph receptor B4b0.101
dlx2adistal-less homeobox gene 2a0.098
emx3empty spiracles homeobox 30.090
bmp2abone morphogenetic protein 2a0.089
foxa1forkhead box A10.089
nkd1naked cuticle homolog 1 (Drosophila)0.088
emx1empty spiracles homeobox 10.086
wnt8bwingless-type MMTV integration site family, member 8b0.082
efnb3bephrin B3b0.082
notch3notch homolog 30.082
slit1aslit homolog 1a (Drosophila)0.082
nova2neuro-oncological ventral antigen 20.081
efnb2aephrin B2a0.079
hhiphedgehog interacting protein0.077
edn1endothelin 10.074
hoxa11bhomeo box A11b0.073
bmp4bone morphogenetic protein 40.072
six3bsine oculis homeobox homolog 3b0.072
wnt4awingless-type MMTV integration site family, member 4a0.071
neurod4neurogenic differentiation 40.069
rereaarginine-glutamic acid dipeptide (RE) repeats a0.063
fgf10afibroblast growth factor 10a0.060
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.058
axin1axin 10.055
igfbp3insulin-like growth factor binding protein 30.055
spry4sprouty (Drosophila) homolog 40.055
nr2f2nuclear receptor subfamily 2, group F, member 20.053
sp8asp8 transcription factor a0.053
ephb4aeph receptor B4a0.053
cyfip2cytoplasmic FMR1 interacting protein 20.052
arnt2aryl hydrocarbon receptor nuclear translocator 20.052
cdkn1ccyclin-dependent kinase inhibitor 1C (p57, Kip2)0.052
elavl3ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)0.052
tbx5aT-box 5a0.051
fezf2FEZ family zinc finger 20.050
neo1neogenin 10.050
sfrp1asecreted frizzled-related protein 1a0.050
pbx4pre-B-cell leukemia transcription factor 40.048
hoxa13ahomeo box A13a0.048
tac1tachykinin 10.048
extl3exostoses (multiple)-like 30.047
skianuclear oncoprotein skia0.046
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.045
sema3aasemaphorin 3aa0.044
cyp26b1cytochrome P450, family 26, subfamily b, polypeptide 10.041
scrt1ascratch homolog 1, zinc finger protein a (Drosophila)0.040
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Robo1roundabout homolog 1 (Drosophila)0.879
Gli3GLI-Kruppel family member GLI30.864
Slit2slit homolog 2 (Drosophila)0.819
Unc5cunc-5 homolog C (C. elegans)0.702
Ntn1netrin 10.681
Slit3slit homolog 3 (Drosophila)0.673
Bhlhe22basic helix-loop-helix family, member e220.649
Dccdeleted in colorectal carcinoma0.595
Gli2GLI-Kruppel family member GLI20.477
Dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.305
Shhsonic hedgehog0.085
Slit1slit homolog 1 (Drosophila)0.083
Pcsk5proprotein convertase subtilisin/kexin type 50.067
Robo2roundabout homolog 2 (Drosophila)0.065
Fgfr2fibroblast growth factor receptor 20.064
Ror2receptor tyrosine kinase-like orphan receptor 20.063
Ephb2Eph receptor B20.043
Pbx1pre B-cell leukemia transcription factor 10.041
Msx1homeobox, msh-like 10.033
Grb10growth factor receptor bound protein 100.031
Sox11SRY-box containing gene 110.030
Efna2ephrin A20.027
Ptk7PTK7 protein tyrosine kinase 70.025
Fzd2frizzled homolog 2 (Drosophila)0.025
Smosmoothened homolog (Drosophila)0.023
Ebf3early B-cell factor 30.022
Fat4FAT tumor suppressor homolog 4 (Drosophila)0.021
Auts2autism susceptibility candidate 20.021
Tbx3T-box 30.020
Efnb1ephrin B10.020
Cachd1cache domain containing 10.019
En1engrailed 10.018
Fzd8frizzled homolog 8 (Drosophila)0.017
Fgfr1fibroblast growth factor receptor 10.017
Twist2twist homolog 2 (Drosophila)0.017
Myo10myosin X0.016
Tbx2T-box 20.015
Zfhx4zinc finger homeodomain 40.015
Gpc3glypican 30.015
Irs1insulin receptor substrate 10.014
Cacng4calcium channel, voltage-dependent, gamma subunit 40.014
Meis2Meis homeobox 20.013
Gpc6glypican 60.013
Hmx2H6 homeobox 20.013
Hoxa10homeobox A100.013
Gli1GLI-Kruppel family member GLI10.013
Hoxd3homeobox D30.013
Foxc2forkhead box C20.012
Capn6calpain 60.012
Fgf8fibroblast growth factor 80.012
Gfra3glial cell line derived neurotrophic factor family receptor alpha 30.012
Fgf10fibroblast growth factor 100.011
Hoxb3homeobox B30.011
Fgfr4fibroblast growth factor receptor 40.011
Nr2f2nuclear receptor subfamily 2, group F, member 20.011
Tbrachyury0.011
Igf1rinsulin-like growth factor I receptor0.011
Gas1growth arrest specific 10.011
Zfpm2zinc finger protein, multitype 20.011
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.011
Col9a1collagen, type IX, alpha 10.011
Fignfidgetin0.011
Tgfb2transforming growth factor, beta 20.010
Vstm2bV-set and transmembrane domain containing 2B0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism