The network for 'developmental induction' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

developmental induction

Signaling at short range between cells or tissues of different ancestry and developmental potential that results in one cell or tissue effecting a developmental change in the other.

NameDescriptionProbabilityFunc Analog Organism
lin-29Protein LIN-290.504
egl-36Protein EGL-360.417
wrm-1Protein WRM-10.291
bar-1Protein BAR-10.234
igcm-3Protein IGCM-30.159
egl-8Protein EGL-80.053
wdr-5.3Protein WDR-5.30.047
let-60Protein LET-600.042
pha-4Protein PHA-40.042
gck-2Protein GCK-20.040
ing-3Protein ING-30.038
unc-53Protein UNC-530.035
egl-13Protein EGL-130.035
let-756Protein LET-7560.034
sma-9Protein SMA-90.033
CELE_T04H1.2Protein T04H1.20.033
soc-2Protein SOC-20.033
pop-1Protein POP-10.033
pry-1Protein PRY-10.032
cyb-3Protein CYB-30.029
rpy-1Protein RPY-10.027
pept-3Protein PEPT-30.027
lin-36Protein LIN-360.026
snt-4Protein SNT-40.025
nhr-34Protein NHR-340.025
mef-2Protein MEF-20.025
lag-1Protein LAG-10.025
ain-1Protein AIN-10.024
egl-23Protein EGL-230.023
tag-260Protein TAG-2600.023
cfim-2Protein CFIM-20.023
egl-30Protein EGL-300.022
slr-2Protein SLR-20.022
saeg-1Protein SAEG-10.022
cfz-2Protein CFZ-20.021
sas-4Protein SAS-40.020
dsh-2Protein DSH-20.020
atg-18Protein ATG-180.019
R05G6.10Protein R05G6.100.018
shk-1Protein SHK-10.018
gei-4Protein GEI-40.018
dbl-1Protein DBL-10.017
duo-1Protein DUO-10.017
pde-4Protein PDE-40.017
somi-1Protein SOMI-10.017
K07B1.7Protein K07B1.70.016
swsn-2.2Protein SWSN-2.20.016
tag-298Protein TAG-2980.015
ceh-32Protein CEH-320.015
CELE_F59A6.5Protein F59A6.50.014
ZK507.6Protein ZK507.60.014
flh-1Protein FLH-10.014
sox-3Protein SOX-30.013
sdn-1Protein SDN-10.013
R02D5.1Protein R02D5.10.013
exp-2Protein EXP-20.013
R05D3.2Protein R05D3.20.013
T26A5.6Protein T26A5.60.013
F31C3.3Protein F31C3.30.013
ZK54.1Protein ZK54.10.013
clk-2Protein CLK-20.013
lgc-39Protein LGC-390.012
kcnl-2Protein KCNL-20.012
ptr-9Protein PTR-90.012
ergo-1Protein ERGO-10.012
tag-253Protein TAG-2530.012
din-1Protein DIN-10.012
plc-1Protein PLC-10.012
ccz-1Protein CCZ-10.012
dpy-27Protein DPY-270.012
nhr-46Protein NHR-460.012
tab-1Protein TAB-10.012
unc-10Protein UNC-100.011
F13C5.2Protein F13C5.20.011
F31E3.2Protein F31E3.20.011
trim-9Protein TRIM-90.011
unc-49Protein UNC-490.011
unc-73Protein UNC-730.011
pkn-1Protein PKN-10.011
axl-1Protein AXL-10.011
F35A5.4Protein F35A5.40.011
ksr-1Protein KSR-10.011
air-2Protein AIR-20.011
F21D12.3Protein F21D12.30.011
swsn-6Protein SWSN-60.010
F31B9.3Protein F31B9.30.010
lin-12Protein LIN-120.010
F38B6.2Protein F38B6.20.010
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
wnt10awingless-type MMTV integration site family, member 10a0.902
fgf3fibroblast growth factor 30.865
ndr2nodal-related 20.779
tbx1T-box 10.510
ventventral expressed homeobox0.453
gli1GLI-Kruppel family member 10.441
gbx2gastrulation brain homeo box 20.439
hmx4H6 family homeobox 40.424
bmp2bbone morphogenetic protein 2b0.414
chsy1chondroitin sulfate synthase 10.350
bmp4bone morphogenetic protein 40.349
flhfloating head0.306
wnt5bwingless-type MMTV integration site family, member 5b0.301
sfrp1asecreted frizzled-related protein 1a0.298
hmx1H6 homeo box 10.227
tbx18T-box 180.219
bmp2abone morphogenetic protein 2a0.217
wnt4awingless-type MMTV integration site family, member 4a0.196
wnt8bwingless-type MMTV integration site family, member 8b0.168
ndr1nodal-related 10.162
wnt8awingless-type MMTV integration site family, member 8a0.160
pcdh8protocadherin 80.157
hoxa11ahomeo box A11a0.144
eya1eyes absent homolog 10.134
fgf17fibroblast growth factor 170.130
eng2aengrailed 2a0.127
wnt11rwingless-type MMTV integration site family, member 11, related0.112
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.105
wnt2bbwingless-type MMTV integration site family, member 2Bb0.104
foxg1aforkhead box G1a0.087
wnt2wingless-type MMTV integration site family member 20.086
hoxa13bhomeo box A13b0.085
dkk1bdickkopf 1b0.082
dusp6dual specificity phosphatase 60.079
col2a1acollagen type II, alpha-1a0.079
wnt9awingless-type MMTV integration site family, member 9A0.079
frem3Fras1 related extracellular matrix 30.078
sox17SRY-box containing gene 170.076
sox32SRY-box containing gene 320.076
mespamesoderm posterior a0.076
rargbretinoic acid receptor, gamma b0.076
nipblbnovel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila)0.075
wif1wnt inhibitory factor 10.074
map2k4amitogen-activated protein kinase kinase 4a0.070
hoxd10ahomeo box D10a0.070
cdh2cadherin 2, neuronal0.065
pax2apaired box gene 2a0.064
lhx2bLIM homeobox 2b0.063
shhasonic hedgehog a0.061
hoxd11ahomeo box D11a0.059
ippkinositol 1,3,4,5,6-pentakisphosphate 2-kinase0.056
tbpl2TATA box binding protein like 20.054
wnt10bwingless-type MMTV integration site family, member 10b0.054
ntlano tail a0.054
igf1rbinsulin-like growth factor 1b receptor0.052
acvr2bactivin receptor IIb0.052
dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.051
tnfsf10l3tumor necrosis factor (ligand) superfamily, member 10 like 30.051
foxd3forkhead box D30.050
otx1aorthodenticle homolog 1a0.049
wnt1wingless-type MMTV integration site family, member 10.048
rx3retinal homeobox gene 30.048
spry4sprouty (Drosophila) homolog 40.048
oepone-eyed pinhead0.048
runx2brunt-related transcription factor 2b0.047
evx2even-skipped homeobox 20.046
foxi1forkhead box I10.044
her5hairy-related 50.044
mibmind bomb0.043
mxtx2mix-type homeobox gene 20.043
crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.043
axin1axin 10.042
prdm1aPR domain containing 1a, with ZNF domain0.041
wnt7aawingless-type MMTV integration site family, member 7Aa0.041
ptch1patched 10.040
voxventral homeobox0.039
msxcmuscle segment homeobox C0.038
six4bsine oculis homeobox homolog 4b0.036
tbx5aT-box 5a0.036
foxd5forkhead box D50.036
msxbmuscle segment homeobox B0.035
gdnfglial cell derived neurotrophic factor0.033
mespbmesoderm posterior b0.032
zfyve26zinc finger, FYVE domain containing 260.032
pdlim7PDZ and LIM domain 70.029
brd4bromodomain containing 40.029
wnt9bwingless-type MMTV integration site family, member 9B0.029
wnt3wingless-type MMTV integration site family, member 30.029
vsx1visual system homeobox 1 homolog, chx10-like0.029
nkx3.2NK3 homeobox 20.028
restRE1-silencing transcription factor0.028
msxemuscle segment homeobox E0.028
vax2ventral anterior homeobox 20.028
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
eyaeyes absent0.781
sogshort gastrulation0.539
stumpsCG31317 gene product from transcript CG31317-RC0.345
EgfrEpidermal growth factor receptor0.334
elavembryonic lethal abnormal vision0.141
Wnt2Wnt oncogene analog 20.130
dallydivision abnormally delayed0.096
toytwin of eyeless0.093
argosCG4531 gene product from transcript CG4531-RA0.089
nkdnaked cuticle0.080
slp2sloppy paired 20.059
Abd-BAbdominal B0.057
fz2frizzled 20.049
slp1sloppy paired 10.047
gcmglial cells missing0.045
Traf4TNF-receptor-associated factor 40.043
zfh2Zn finger homeodomain 20.041
vvlventral veins lacking0.041
wbwing blister0.039
cicubitus interruptus0.034
Wnt5Wnt oncogene analog 50.033
CG8965CG8965 gene product from transcript CG8965-RA0.032
opaodd paired0.031
GckIIIGerminal centre kinase III0.031
form3formin 30.030
lblladybird late0.029
ph-dpolyhomeotic distal0.026
salmspalt major0.026
MrtfMyocardin-related transcription factor0.023
mewmultiple edematous wings0.022
aopanterior open0.021
sosine oculis0.020
Bacebeta-site APP-cleaving enzyme0.020
Gef26CG9491 gene product from transcript CG9491-RB0.019
14-3-3zetaCG17870 gene product from transcript CG17870-RB0.018
NotumCG13076 gene product from transcript CG13076-RB0.018
pburspartner of burs0.017
HimHoles in muscle0.017
jebjelly belly0.017
OptixCG18455 gene product from transcript CG18455-RA0.016
nimC3nimrod C30.016
zfh1Zn finger homeodomain 10.016
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
FGFR1fibroblast growth factor receptor 10.665
FGFR2fibroblast growth factor receptor 20.626
CSNK1Ecasein kinase 1, epsilon0.491
SP1Sp1 transcription factor0.476
FGF1fibroblast growth factor 1 (acidic)0.396
CREBBPCREB binding protein0.350
DVL3dishevelled, dsh homolog 3 (Drosophila)0.246
APCadenomatous polyposis coli0.134
BMPR1Abone morphogenetic protein receptor, type IA0.126
NCOA2nuclear receptor coactivator 20.107
FOXD3forkhead box D30.099
LRP6low density lipoprotein receptor-related protein 60.072
FGF2fibroblast growth factor 2 (basic)0.071
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.067
DVL1dishevelled, dsh homolog 1 (Drosophila)0.065
SOX2SRY (sex determining region Y)-box 20.055
PAX3paired box 30.054
SOX10SRY (sex determining region Y)-box 100.050
NEDD4neural precursor cell expressed, developmentally down-regulated 40.048
POU5F1POU class 5 homeobox 10.045
BBS10Bardet-Biedl syndrome 100.040
CTNNBIP1catenin, beta interacting protein 10.038
MDFIMyoD family inhibitor0.035
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.033
AXIN1axin 10.029
WWP2WW domain containing E3 ubiquitin protein ligase 20.027
TCF7L2transcription factor 7-like 2 (T-cell specific, HMG-box)0.016
MYST2MYST histone acetyltransferase 20.016
WT1Wilms tumor 10.015
SMAD4SMAD family member 40.015
WNT5Awingless-type MMTV integration site family, member 5A0.014
FRS2fibroblast growth factor receptor substrate 20.014
LRRK2leucine-rich repeat kinase 20.014
FSTL1follistatin-like 10.013
PAX8paired box 80.012
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.011
SMAD1SMAD family member 10.011
RASSF5Ras association (RalGDS/AF-6) domain family member 50.010
SNIP1Smad nuclear interacting protein 10.010
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Fgfr2fibroblast growth factor receptor 21.000
Hoxd11homeobox D110.997
Fgf8fibroblast growth factor 80.997
Pax2paired box gene 20.997
Gli3GLI-Kruppel family member GLI30.989
Sall4sal-like 4 (Drosophila)0.980
Alx4aristaless-like homeobox 40.980
Otx2orthodenticle homolog 2 (Drosophila)0.974
Hand1heart and neural crest derivatives expressed transcript 10.956
Pou3f3POU domain, class 3, transcription factor 30.953
Hoxd13homeobox D130.952
Pax3paired box gene 30.948
Isl1ISL1 transcription factor, LIM/homeodomain0.901
Foxc1forkhead box C10.893
Rargretinoic acid receptor, gamma0.885
Lhx1LIM homeobox protein 10.879
Fgfr1fibroblast growth factor receptor 10.867
Hand2heart and neural crest derivatives expressed transcript 20.864
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.864
Fgf10fibroblast growth factor 100.855
Tcfap2atranscription factor AP-2, alpha0.828
Tbx1T-box 10.794
Hoxa13homeobox A130.793
Retret proto-oncogene0.774
Lhx3LIM homeobox protein 30.769
Dvl2dishevelled 2, dsh homolog (Drosophila)0.766
Sall3sal-like 3 (Drosophila)0.761
Sox2SRY-box containing gene 20.759
Pou5f1POU domain, class 5, transcription factor 10.754
Pax8paired box gene 80.751
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.750
Sox9SRY-box containing gene 90.716
Pitx2paired-like homeodomain transcription factor 20.703
Ror2receptor tyrosine kinase-like orphan receptor 20.690
Wnt3awingless-related MMTV integration site 3A0.687
Dok1docking protein 10.668
Ptk7PTK7 protein tyrosine kinase 70.652
Ascl1achaete-scute complex homolog 1 (Drosophila)0.639
Fgf3fibroblast growth factor 30.622
Fzd8frizzled homolog 8 (Drosophila)0.618
Vangl1vang-like 1 (van gogh, Drosophila)0.568
Hspg2perlecan (heparan sulfate proteoglycan 2)0.564
Nkx2-3NK2 transcription factor related, locus 3 (Drosophila)0.560
Smad6MAD homolog 6 (Drosophila)0.550
Atoh7atonal homolog 7 (Drosophila)0.539
NanogNanog homeobox0.539
Vangl2vang-like 2 (van gogh, Drosophila)0.538
Alx3aristaless-like homeobox 30.536
Grb2growth factor receptor bound protein 20.527
Insm1insulinoma-associated 10.505
Dkk1dickkopf homolog 1 (Xenopus laevis)0.495
Tbx2T-box 20.472
Gli2GLI-Kruppel family member GLI20.463
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.438
Wnt6wingless-related MMTV integration site 60.437
Dvl3dishevelled 3, dsh homolog (Drosophila)0.434
Inpp5dinositol polyphosphate-5-phosphatase D0.401
Dlx5distal-less homeobox 50.396
Msx1homeobox, msh-like 10.377
Fgf15fibroblast growth factor 150.372
Foxh1forkhead box H10.363
Sall1sal-like 1 (Drosophila)0.362
Vax1ventral anterior homeobox containing gene 10.357
Sox1SRY-box containing gene 10.354
Six3sine oculis-related homeobox 3 homolog (Drosophila)0.343
Ntf3neurotrophin 30.340
Zic3zinc finger protein of the cerebellum 30.339
Eya1eyes absent 1 homolog (Drosophila)0.339
Pou3f1POU domain, class 3, transcription factor 10.328
Fgf9fibroblast growth factor 90.317
Fgf4fibroblast growth factor 40.298
Sox3SRY-box containing gene 30.282
Gata4GATA binding protein 40.281
UncxUNC homeobox0.280
Tbx3T-box 30.280
Spry4sprouty homolog 4 (Drosophila)0.279
Tead3TEA domain family member 30.270
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.269
Foxb1forkhead box B10.266
Prrx1paired related homeobox 10.261
Sox10SRY-box containing gene 100.259
Pitx1paired-like homeodomain transcription factor 10.251
Pou4f3POU domain, class 4, transcription factor 30.245
Nkx6-1NK6 homeobox 10.245
Foxf1aforkhead box F1a0.243
Wnt9bwingless-type MMTV integration site 9B0.240
Foxd2forkhead box D20.239
Tlx2T-cell leukemia, homeobox 20.238
Pax6paired box gene 60.237
Hmx3H6 homeobox 30.236
Lmx1aLIM homeobox transcription factor 1 alpha0.235
Wnt4wingless-related MMTV integration site 40.231
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.229
Ror1receptor tyrosine kinase-like orphan receptor 10.226
Spry2sprouty homolog 2 (Drosophila)0.218
Tbx15T-box 150.212
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cxxc4CXXC finger 40.226
Foxc2forkhead box C20.209
Unc5bunc-5 homolog B (C. elegans)0.092
Fxyd7FXYD domain-containing ion transport regulator 70.087
Lipflipase, gastric0.087
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.086
Glg1golgi apparatus protein 10.086
Gja3gap junction protein, alpha 30.080
Pde3aphosphodiesterase 3A, cGMP inhibited0.080
Syt9synaptotagmin IX0.073
Olfml2bolfactomedin-like 2B0.071
P2rx6purinergic receptor P2X, ligand-gated ion channel, 60.070
Plb1phospholipase B10.065
Magi2membrane associated guanylate kinase, WW and PDZ domain containing 20.061
Kcnj5potassium inwardly-rectifying channel, subfamily J, member 50.057
Fgf5fibroblast growth factor 50.057
Fgf10fibroblast growth factor 100.056
Adamts13ADAM metallopeptidase with thrombospondin type 1 motif, 130.056
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.055
Slc5a1solute carrier family 5 (sodium/glucose cotransporter), member 10.055
Cela2achymotrypsin-like elastase family, member 2A0.053
Prrx1paired related homeobox 10.052
Cst12cystatin 120.049
Stmn4stathmin-like 40.049
Masp1mannan-binding lectin serine peptidase 10.048
Pga5pepsinogen 5, group I0.048
Tbr1T-box, brain, 10.046
Dact3dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)0.045
Ednraendothelin receptor type A0.044
Pmfbp1polyamine modulated factor 1 binding protein 10.043
Mycsmyc-like oncogene, s-myc protein0.043
Prok1prokineticin 10.043
Cpa3carboxypeptidase A3, mast cell0.042
Chrnb3cholinergic receptor, nicotinic, beta 30.042
Gucy2fguanylate cyclase 2F0.038
Cdh6cadherin 60.038
Pde7bphosphodiesterase 7B0.038
Cpxm2carboxypeptidase X (M14 family), member 20.037
Pclopiccolo (presynaptic cytomatrix protein)0.037
Slc22a2solute carrier family 22 (organic cation transporter), member 20.036
Neurl1Bneuralized homolog 1B (Drosophila)0.036
Kcnh5potassium voltage-gated channel, subfamily H (eag-related), member 50.035
Rpl3lribosomal protein L3-like0.035
Lcn5lipocalin 50.035
Mpripmyosin phosphatase Rho interacting protein0.034
A2bp1ataxin 2 binding protein 10.034
Lifrleukemia inhibitory factor receptor alpha0.033
Slc13a1solute carrier family 13 (sodium/sulfate symporters), member 10.033
Kcnh7potassium voltage-gated channel, subfamily H (eag-related), member 70.033
Gabrb3gamma-aminobutyric acid (GABA) A receptor, beta 30.031
Ryr2ryanodine receptor 2, cardiac0.031
Trim66tripartite motif-containing 660.031
Il23aInterleukin 23, alpha subunit p190.031
Sod3superoxide dismutase 3, extracellular0.031
Klrb1akiller cell lectin-like receptor subfamily B, member 1A0.031
Cercamcerebral endothelial cell adhesion molecule0.031
Kcns2potassium voltage-gated channel, delayed-rectifier, subfamily S, member 20.030
Erbb4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.030
Prokr1prokineticin receptor 10.030
Sox13SRY (sex determining region Y)-box 130.030
Tnni1troponin I type 1 (skeletal, slow)0.030
Slc10a2solute carrier family 10 (sodium/bile acid cotransporter family), member 20.029
Crybb2crystallin, beta B20.029
Hist1h1dhistone cluster 1, H1d0.029
Olr1867olfactory receptor 18670.029
Cyp1a1cytochrome P450, family 1, subfamily a, polypeptide 10.029
Akt2v-akt murine thymoma viral oncogene homolog 20.029
CebpeCCAAT/enhancer binding protein (C/EBP), epsilon0.029
Rab3il1RAB3A interacting protein (rabin3)-like 10.028
Acvr1activin A receptor, type I0.028
MrgprfMAS-related GPR, member F0.028
Gcm1glial cells missing homolog 1 (Drosophila)0.028
Fgf8fibroblast growth factor 80.027
MosMoloney sarcoma oncogene0.027
Il11interleukin 110.027
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.026
Ctsjcathepsin J0.026
Cav3caveolin 30.026
Ptgfrprostaglandin F receptor0.026
Ins2insulin 20.026
Slc3a1solute carrier family 3, member 10.026
Asb9ankyrin repeat and SOCS box-containing 90.026
Stk11serine/threonine kinase 110.026
Cacng7calcium channel, voltage-dependent, gamma subunit 70.025
Hcn3hyperpolarization-activated cyclic nucleotide-gated potassium channel 30.025
Gfi1growth factor independent 1 transcription repressor0.025
Adrb1adrenergic, beta-1-, receptor0.025
Hspb3heat shock protein 30.025
Hoxb7homeo box B70.025
Serpinb7serpin peptidase inhibitor, clade B (ovalbumin), member 70.025
Psgb1pregnancy-specific beta 1-glycoprotein0.024
RGD1564664similar to LOC387763 protein0.024
Fcer2Fc fragment of IgE, low affinity II, receptor for (CD23)0.024
Myoz1myozenin 10.024
Creb1cAMP responsive element binding protein 10.024
Ltalymphotoxin alpha (TNF superfamily, member 1)0.024
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism