The network for 'negative regulation of cellular protein catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of cellular protein catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein catabolic process.

NameDescriptionProbabilityFunc Analog Organism
gpr-2Protein GPR-20.048
spdl-1Protein SPDL-10.031
his-45Protein HIS-450.030
imb-2Protein IMB-20.027
gpr-1Protein GPR-10.027
ZK1127.5Protein ZK1127.50.025
npp-11Protein NPP-110.023
F15D4.2Protein F15D4.20.022
his-6Protein HIS-60.022
bmk-1Protein BMK-10.022
goa-1Protein GOA-10.021
let-502Protein LET-5020.021
hcp-1Protein HCP-10.021
spk-1Protein SPK-10.020
lmn-1Protein LMN-10.019
his-42Protein HIS-420.019
ZK507.6Protein ZK507.60.018
C49H3.9Protein C49H3.90.018
bli-1Protein BLI-10.018
W09D10.1Protein W09D10.10.017
ani-1Protein ANI-10.017
rnr-1Protein RNR-10.017
gex-3Protein GEX-30.017
R11A8.7Protein R11A8.70.017
air-1Protein AIR-10.016
math-33Protein MATH-330.016
abl-1Protein ABL-10.016
ntl-4Protein NTL-40.016
tba-2Protein TBA-20.016
sac-1Protein SAC-10.016
lin-13Protein LIN-130.015
cls-2Protein CLS-20.015
lin-23Protein LIN-230.015
mus-101Protein MUS-1010.015
him-10Protein HIM-100.014
htz-1Protein HTZ-10.014
cyp-31A2Protein CYP-31A20.014
F25B3.6Protein F25B3.60.014
tsp-14Protein TSP-140.014
mrck-1Protein MRCK-10.014
uaf-1Protein UAF-10.014
asd-1Protein ASD-10.014
csn-5Protein CSN-50.014
CELE_E01G4.6Protein E01G4.60.014
cul-2Protein CUL-20.013
rpb-2Protein RPB-20.013
pptr-2Protein PPTR-20.013
CELE_F02E9.10Protein F02E9.100.013
hgrs-1Protein HGRS-10.013
syx-17Protein SYX-170.013
snr-2Protein SNR-20.013
gmn-1Protein GMN-10.013
CELE_C36A4.4Protein C36A4.40.013
pac-1Protein PAC-10.013
mel-11Protein MEL-110.012
CELE_C24H12.5Protein C24H12.50.012
csn-1Protein CSN-10.012
his-32Protein HIS-320.012
CELE_K08F4.1Protein K08F4.10.012
unc-116Protein UNC-1160.012
col-111Protein COL-1110.012
lin-5Protein LIN-50.012
wht-7Protein WHT-70.012
prp-21Protein PRP-210.012
CELE_ZK1025.3Protein ZK1025.30.012
gck-1Protein GCK-10.012
apc-10Protein APC-100.012
mig-15Protein MIG-150.012
B0336.3Protein B0336.30.012
grd-2Protein GRD-20.012
oac-30Protein OAC-300.012
D1081.8Protein D1081.80.012
cyk-4Protein CYK-40.012
T12B3.4Protein T12B3.40.012
hat-1Protein HAT-10.011
cyn-4Protein CYN-40.011
ubq-1Protein UBQ-10.011
bah-1Protein BAH-10.011
col-172Protein COL-1720.011
smc-3Protein SMC-30.011
sop-3Protein SOP-30.011
hda-3Protein HDA-30.011
T22C1.1Protein T22C1.10.011
zyg-9Protein ZYG-90.011
F44E2.8Protein F44E2.80.011
rpt-5Protein RPT-50.011
mlt-10Protein MLT-100.011
Y55F3BR.8Protein Y55F3BR.80.011
rpb-7Protein RPB-70.011
exos-1Protein EXOS-10.011
C02B10.5Protein C02B10.50.011
rsd-6Protein RSD-60.011
hmp-1Protein HMP-10.011
noca-1Protein NOCA-10.011
grd-1Protein GRD-10.011
CELE_C25A1.4Protein C25A1.40.011
B0491.1Protein B0491.10.011
sec-31Protein SEC-310.011
his-47Protein HIS-470.011
gld-1Protein GLD-10.011
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
IswiImitation SWI0.020
IncenpInner centromere protein0.014
fzyfizzy0.012
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.924
CDC27cell division cycle 27 homolog (S. cerevisiae)0.819
ANAPC5anaphase promoting complex subunit 50.532
CDC20cell division cycle 20 homolog (S. cerevisiae)0.456
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.455
ANAPC1anaphase promoting complex subunit 10.447
BUB1budding uninhibited by benzimidazoles 1 homolog (yeast)0.353
SKP1S-phase kinase-associated protein 10.320
BUB3budding uninhibited by benzimidazoles 3 homolog (yeast)0.224
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.195
FASFas (TNF receptor superfamily, member 6)0.187
TP53BP1tumor protein p53 binding protein 10.133
CCNA2cyclin A20.132
MRE11AMRE11 meiotic recombination 11 homolog A (S. cerevisiae)0.119
TP53tumor protein p530.115
MED15mediator complex subunit 150.114
RAD21RAD21 homolog (S. pombe)0.111
CCT8chaperonin containing TCP1, subunit 8 (theta)0.111
SP100SP100 nuclear antigen0.104
TPBGtrophoblast glycoprotein0.100
CDK2cyclin-dependent kinase 20.098
H2AFXH2A histone family, member X0.096
ANAPC4anaphase promoting complex subunit 40.092
BRCA2breast cancer 2, early onset0.089
ASF1AASF1 anti-silencing function 1 homolog A (S. cerevisiae)0.088
ZNF263zinc finger protein 2630.086
CCND1cyclin D10.084
CASC5cancer susceptibility candidate 50.080
MDC1mediator of DNA-damage checkpoint 10.078
FANCD2Fanconi anemia, complementation group D20.077
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme0.075
NBNnibrin0.073
PSEN1presenilin 10.072
MLLT6myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 60.070
SOD1superoxide dismutase 1, soluble0.068
CCNB1cyclin B10.067
PSMD12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.065
ZNF207zinc finger protein 2070.063
TINF2TERF1 (TRF1)-interacting nuclear factor 20.063
SKP2S-phase kinase-associated protein 2 (p45)0.063
NBR1neighbor of BRCA1 gene 10.062
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.060
FXR2fragile X mental retardation, autosomal homolog 20.058
RBCK1RanBP-type and C3HC4-type zinc finger containing 10.057
CDC5LCDC5 cell division cycle 5-like (S. pombe)0.055
GABARAPL1GABA(A) receptor-associated protein like 10.054
ANKRD52ankyrin repeat domain 520.054
SMAD2SMAD family member 20.051
BRCA1breast cancer 1, early onset0.051
PAXIP1PAX interacting (with transcription-activation domain) protein 10.050
HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 10.050
COPS8COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)0.050
ANAPC11anaphase promoting complex subunit 110.049
BAG2BCL2-associated athanogene 20.048
DAXXdeath-domain associated protein0.048
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.048
CD2BP2CD2 (cytoplasmic tail) binding protein 20.047
PSEN2presenilin 2 (Alzheimer disease 4)0.047
UBE2D4ubiquitin-conjugating enzyme E2D 4 (putative)0.046
KPNA3karyopherin alpha 3 (importin alpha 4)0.046
TRIM39tripartite motif containing 390.045
MAP3K5mitogen-activated protein kinase kinase kinase 50.044
STX5syntaxin 50.043
TOR1Atorsin family 1, member A (torsin A)0.043
ORC2origin recognition complex, subunit 20.042
C19orf39chromosome 19 open reading frame 390.042
CENPEcentromere protein E, 312kDa0.042
DOT1LDOT1-like, histone H3 methyltransferase (S. cerevisiae)0.041
PRPF6PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)0.040
MAP1LC3Bmicrotubule-associated protein 1 light chain 3 beta0.040
MAD2L1MAD2 mitotic arrest deficient-like 1 (yeast)0.039
SMC3structural maintenance of chromosomes 30.039
RFWD2ring finger and WD repeat domain 20.038
SYVN1synovial apoptosis inhibitor 1, synoviolin0.038
MED1mediator complex subunit 10.038
HUWE1HECT, UBA and WWE domain containing 10.037
FBXO5F-box protein 50.037
GFI1Bgrowth factor independent 1B transcription repressor0.037
EP300E1A binding protein p3000.037
CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1)0.036
CREBBPCREB binding protein0.036
TRIM26tripartite motif containing 260.035
ZC3HAV1zinc finger CCCH-type, antiviral 10.035
TERF1telomeric repeat binding factor (NIMA-interacting) 10.035
GFERgrowth factor, augmenter of liver regeneration0.035
RAD51RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)0.034
PRNPprion protein0.033
NCSTNnicastrin0.033
HERC2hect domain and RLD 20.033
NDC80NDC80 homolog, kinetochore complex component (S. cerevisiae)0.033
SMARCB1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 10.033
ANAPC7anaphase promoting complex subunit 70.033
PPP1CCprotein phosphatase 1, catalytic subunit, gamma isozyme0.033
CHD4chromodomain helicase DNA binding protein 40.033
CDKN3cyclin-dependent kinase inhibitor 30.032
TRIM21tripartite motif containing 210.031
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.031
TRIM5tripartite motif containing 50.031
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.031
LMNAlamin A/C0.030
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 530.997
Ctnnb1catenin (cadherin associated protein), beta 10.913
Cdk1cyclin-dependent kinase 10.726
Pax2paired box gene 20.699
Psen1presenilin 10.672
Ccnb1cyclin B10.660
Notch1Notch gene homolog 1 (Drosophila)0.587
Ccna2cyclin A20.520
Ptenphosphatase and tensin homolog0.449
Trp73transformation related protein 730.423
Amhr2anti-Mullerian hormone type 2 receptor0.324
Fgfr2fibroblast growth factor receptor 20.315
Prc1protein regulator of cytokinesis 10.313
Brca2breast cancer 20.311
Ccnb2cyclin B20.298
Gli3GLI-Kruppel family member GLI30.296
Birc5baculoviral IAP repeat-containing 50.271
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.255
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.235
Rb1retinoblastoma 10.231
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.225
Notch2Notch gene homolog 2 (Drosophila)0.218
Ncstnnicastrin0.193
Mdm2transformed mouse 3T3 cell double minute 20.191
Shhsonic hedgehog0.189
Kif22kinesin family member 220.187
Kif20akinesin family member 20A0.186
Pax8paired box gene 80.180
Cdk2cyclin-dependent kinase 20.176
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.170
Ptch1patched homolog 10.166
Wnt3awingless-related MMTV integration site 3A0.157
SkilSKI-like0.153
Dkk1dickkopf homolog 1 (Xenopus laevis)0.144
Cdca8cell division cycle associated 80.139
Lhx1LIM homeobox protein 10.136
Wnt4wingless-related MMTV integration site 40.124
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.123
Hmmrhyaluronan mediated motility receptor (RHAMM)0.123
Sap18Sin3-associated polypeptide 180.121
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.119
Arid1bAT rich interactive domain 1B (SWI-like)0.116
Sgol2shugoshin-like 2 (S. pombe)0.112
C330027C09RikRIKEN cDNA C330027C09 gene0.105
Aurkbaurora kinase B0.104
Ooepoocyte expressed protein homolog (dog)0.101
Cdkn2ccyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)0.100
Cdkn1bcyclin-dependent kinase inhibitor 1B0.092
Aimp1aminoacyl tRNA synthetase complex-interacting multifunctional protein 10.091
Cops6COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana)0.090
Emx2empty spiracles homolog 2 (Drosophila)0.082
Axin1axin 10.082
Leprleptin receptor0.080
Arandrogen receptor0.075
Vdac3voltage-dependent anion channel 30.070
Gsk3bglycogen synthase kinase 3 beta0.069
Kif11kinesin family member 110.069
Foxc1forkhead box C10.069
Spag5sperm associated antigen 50.066
Tbrachyury0.065
Kntc1kinetochore associated 10.061
Aph1aanterior pharynx defective 1a homolog (C. elegans)0.060
Ckap2cytoskeleton associated protein 20.057
Ube2cubiquitin-conjugating enzyme E2C0.056
BrafBraf transforming gene0.056
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.055
Cks2CDC28 protein kinase regulatory subunit 20.052
Mki67antigen identified by monoclonal antibody Ki 670.051
Bub1budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)0.051
Ror2receptor tyrosine kinase-like orphan receptor 20.050
Socs1suppressor of cytokine signaling 10.050
Klklotho0.049
Nek2NIMA (never in mitosis gene a)-related expressed kinase 20.049
Cbx1chromobox homolog 1 (Drosophila HP1 beta)0.049
Bmp7bone morphogenetic protein 70.049
Dll1delta-like 1 (Drosophila)0.049
Acdadrenocortical dysplasia0.047
Wnt1wingless-related MMTV integration site 10.047
Wnt10bwingless related MMTV integration site 10b0.046
Sox9SRY-box containing gene 90.045
Smarcb1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 10.045
Rrm2ribonucleotide reductase M20.045
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.045
Hoxd11homeobox D110.044
4632434I11RikRIKEN cDNA 4632434I11 gene0.043
Fzd10frizzled homolog 10 (Drosophila)0.043
Nf1neurofibromatosis 10.043
Ube2tubiquitin-conjugating enzyme E2T (putative)0.042
Hoxa13homeobox A130.042
Drap1Dr1 associated protein 1 (negative cofactor 2 alpha)0.042
Hist1h2bmhistone cluster 1, H2bm0.042
Arid1aAT rich interactive domain 1A (SWI-like)0.042
Kif4kinesin family member 40.041
Rararetinoic acid receptor, alpha0.041
Ccnfcyclin F0.041
Dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.041
Fgf18fibroblast growth factor 180.040
DaxxFas death domain-associated protein0.040
Col2a1collagen, type II, alpha 10.039
Wnt9awingless-type MMTV integration site 9A0.039
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
MAD2Mad2p0.641
PPH22Pph22p0.603
CDC55Cdc55p0.514
PPH21Pph21p0.466
HHF2Hhf2p0.404
CTF13Ctf13p0.397
RTS1Rts1p0.383
SLK19Slk19p0.353
YPI1Ypi1p0.305
CDC20Cdc20p0.285
SLI15Sli15p0.171
KIP1Kip1p0.162
IML3Iml3p0.155
MAD3Mad3p0.143
CHL4Chl4p0.142
PIG2Pig2p0.129
NBL1Nbl1p0.122
FMP48Fmp48p0.121
TIP41Tip41p0.116
NSL1Nsl1p0.112
SDS22Sds22p0.081
DSN1Dsn1p0.080
CTF3Ctf3p0.079
MAD1Mad1p0.075
BUB1Bub1p0.074
GIP2Gip2p0.067
PCL10Pcl10p0.064
BRN1Brn1p0.063
GLG1Glg1p0.056
MTW1Mtw1p0.056
ASE1Ase1p0.055
MLC1Mlc1p0.045
HTA1Hta1p0.043
SMC4Smc4p0.042
CSL4Csl4p0.042
TID3Tid3p0.041
CIN8Cin8p0.041
CBF1Cbf1p0.040
RAD23Rad23p0.038
PRS2Prs2p0.038
NTO1Nto1p0.037
PSP1Psp1p0.036
VIK1Vik1p0.035
MPH1Mph1p0.033
RAD24Rad24p0.033
TAF7Taf7p0.032
IRC15Irc15p0.031
SFI1Sfi1p0.031
CSE4Cse4p0.031
RPT6Rpt6p0.031
PPQ1Ppq1p0.031
CDC28Cdc28p0.031
HHT1Hht1p0.030
BIR1Bir1p0.030
YOL038C-Ahypothetical protein0.030
YML053Chypothetical protein0.030
RAD61Rad61p0.030
STB2Stb2p0.030
LEU2Leu2p0.029
MER1Mer1p0.029
SRD1Srd1p0.029
YLR162Whypothetical protein0.029
YBP2Ybp2p0.029
YLR264C-Ahypothetical protein0.028
YIL151Chypothetical protein0.028
CIN1Cin1p0.027
CRP1Crp1p0.027
PRP28Prp28p0.027
GAC1Gac1p0.027
HAL5Hal5p0.026
SWD3Swd3p0.026
ZDS2Zds2p0.026
HHT2Hht2p0.025
YAR068Whypothetical protein0.025
BDF2Bdf2p0.025
YNL144Chypothetical protein0.025
TAF11Taf11p0.025
ZDS1Zds1p0.024
PSK1Psk1p0.024
SET4Set4p0.024
CUP1-1Cup1-1p0.024
CDC48Cdc48p0.024
PRE10Pre10p0.024
NUP49Nup49p0.023
URA3Ura3p0.023
ARG8Arg8p0.023
HYM1Hym1p0.023
SPO12Spo12p0.023
SPL2Spl2p0.023
YGK3Ygk3p0.023
SYN8Syn8p0.023
OKP1Okp1p0.022
YLR042Chypothetical protein0.022
ZPS1Zps1p0.022
FRA2Fra2p0.022
PCT1Pct1p0.022
YDL012Chypothetical protein0.022
TAH11Tah11p0.022
BUB3Bub3p0.022
JLP2Jlp2p0.022